!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!cell	Hepatocytes
!perturbation	Rofecoxib  111 uM - 1 day
!end_metadata
UGT2B17	0.154529
CYP1A1	0.141140
UBD	0.113913
GPM6A	-0.098400
SLC28A2	-0.093398
P2RX5	0.089730
MST1	-0.089502
PLEK2	-0.086296
TMEM255B	-0.075802
NEFL	0.072924
DDR1	0.070995
DCN	0.069434
HMGCS2	-0.068913
LTB	0.068046
B3GALNT1	-0.067391
CD36	-0.063777
OLFML3	-0.063207
PLA1A	-0.062331
CLDN7	0.061340
SEC11C	0.060864
TNFRSF14	-0.058926
ISG15	-0.057949
ABCG2	-0.056509
SLC1A6	0.055687
FAM111A	0.054721
SLC44A4	-0.054039
AKR1B10	-0.053855
WFDC2	-0.052355
SCRN1	-0.050129
GBP6	-0.048271
LTBP1	0.048098
LGALS2	-0.047768
CCL13	0.047459
REXO4	0.047396
LOX	0.046808
TNC	-0.045461
MIS18A	-0.045405
HSD17B6	-0.044867
CPE	-0.044770
ATRNL1	-0.044649
ABCA1	0.044586
GRK5	0.044076
RUNX1	-0.043860
ANGPTL4	-0.043381
PIK3R1	0.043122
RTP4	-0.042540
EXOSC3	-0.042365
ABCC2	0.042197
SLC34A2	-0.041682
FMO1	-0.041625
HAL	0.041446
DYSF	-0.040592
SNX14	-0.040298
TMEM2	-0.040146
TOR3A	-0.039933
CYP2E1	-0.039117
ADAMTS1	-0.039028
SLCO2A1	0.038997
PPIC	0.038891
ZFP14	0.038880
JUND	0.038623
EDN1	-0.038522
TRIM59	-0.038450
SLCO3A1	0.037907
ITGAE	0.037823
FGFR1	0.037365
ADORA2B	-0.037334
TC2N	0.037310
NT5DC1	-0.036734
FAM102B	0.036664
RRM2	0.036512
RELN	-0.036353
SMPDL3B	-0.036223
EGR1	0.036131
TNFRSF11B	-0.036057
NEDD1	-0.035719
FLT4	0.035441
SLC7A11	0.035231
EPCAM	0.035208
GADD45B	0.035018
S100A6	-0.034991
TMEM252	-0.034936
DNASE2B	0.034809
VWA1	-0.034441
PROCR	0.034277
SEMA3B	0.034241
SERPINA7	-0.034208
TXNIP	-0.034118
LHFP	0.033716
IFIT3	-0.033654
AOX1	-0.033488
TGM1	0.033058
EVC	-0.032959
OAT	-0.032853
MTHFD2	0.032760
CRP	0.032659
FNTB	0.032609
GSTP1	0.032207
MYL9	-0.032109
CIB2	0.032064
CCDC77	0.032021
IGFBP1	0.031813
C15orf60	-0.031786
SLC10A1	-0.031756
MRC1	-0.031588
ABCA4	-0.031495
FAM13C	0.031391
ACSL3	0.031305
EHHADH	0.031052
CHDH	-0.030984
GOLT1A	0.030879
PKIB	0.030828
IL1R2	-0.030650
ALDH1A1	-0.030605
AGTR1	0.030582
OARD1	-0.030523
TMEM19	-0.030500
GSTA3	-0.030452
CHAC1	0.030418
COL4A2	0.030336
RASSF9	0.030336
ACOT1	0.030230
CCDC68	0.030227
MOCOS	-0.030003
PRND	-0.029570
LCP1	-0.029565
TCP11L2	0.029554
GCNT1	0.029514
PSD3	0.029459
LGALS1	-0.029440
DGUOK	0.029348
IKBKB	0.029303
C1QA	-0.029284
ARHGEF10	0.029232
KLHL24	0.029125
PKLR	-0.029048
ABLIM1	-0.029014
GCNT2	0.028938
APOM	-0.028830
CPT1A	-0.028666
SYNE4	-0.028604
SPSB4	-0.028339
CALR3	0.028338
P2RY2	0.028321
A2M	-0.028290
SDR16C5	0.028264
BCKDHB	0.028185
SHC4	0.028184
ABCB1	0.028068
SGK2	-0.027941
TMEM45A	-0.027930
VOPP1	-0.027903
DNAJA3	0.027883
HYKK	-0.027835
CEP152	0.027829
IRF7	-0.027807
AQP11	-0.027740
USP4	0.027689
ASNS	0.027654
NUDT11	0.027523
KANK4	-0.027502
EMR1	-0.027440
ATF5	0.027346
PPP1R3B	-0.027273
LRRC8A	0.027143
DIMT1	0.026949
L2HGDH	-0.026932
SEMA3C	0.026882
ID3	-0.026852
FABP7	0.026830
DECR1	-0.026802
ARHGEF2	0.026734
SLC6A8	-0.026712
PSCA	-0.026633
PRIM1	-0.026609
C1QC	-0.026558
ADAMTS5	-0.026252
SAMD9L	-0.026205
CREB3L3	-0.026189
SGCB	-0.026150
PIK3R3	-0.026146
FASN	0.026144
ILF3	-0.026141
TXNRD2	-0.025941
HIP1	0.025917
MED22	-0.025768
IBA57	-0.025700
PRR15	-0.025698
PYCR1	0.025565
AASS	-0.025387
JAG1	0.025258
COL4A5	0.025196
SLC30A1	-0.025188
CCDC115	0.025113
GNA14	0.025084
EMP2	0.025044
YIPF1	-0.025035
FCER1G	-0.025029
ITGA1	0.025018
POLR1B	0.024957
PSMB10	-0.024845
ZNF280B	-0.024820
NR5A2	-0.024743
SLC2A2	-0.024737
COTL1	-0.024671
LY6E	-0.024667
ACADL	-0.024666
PPP2R1B	-0.024570
VIL1	-0.024452
MKI67	0.024446
MAPK9	-0.024395
PCED1B	-0.024345
MMD	0.024341
SEC16B	-0.024334
SERPINA6	-0.024307
CLEC10A	-0.024255
NME4	0.024249
TSPYL4	-0.024239
BBS1	0.024220
TM6SF2	-0.024024
FAM117A	0.024019
BHMT	-0.023961
GPR146	-0.023843
TRAF7	-0.023782
AGRN	-0.023750
AGAP1	-0.023683
AMHR2	0.023620
PROSER2	-0.023513
CCNB2	0.023509
GYS2	-0.023484
LPHN1	-0.023476
EIF4E3	-0.023452
DBP	-0.023450
GJB2	0.023443
CHPT1	-0.023416
SIGLEC8	-0.023378
METRNL	-0.023339
CDCA8	0.023328
BSPRY	0.023293
RRP8	0.023259
KLF10	-0.023230
PLA2G12A	0.023222
ETFDH	-0.023222
CDH17	-0.023195
SAT2	0.023110
SH2B2	0.023083
SLC43A1	0.023056
ASRGL1	0.023036
SLC3A1	-0.023024
OSCP1	0.023016
CX3CL1	0.023014
TMEM176B	-0.022956
CD9	0.022911
LMCD1	0.022881
SLC30A3	0.022859
NLN	-0.022849
PTPN13	0.022837
RTEL1	-0.022827
PNPO	-0.022791
FABP2	-0.022697
TINAGL1	0.022664
CUEDC2	0.022631
RETSAT	0.022621
SSBP2	0.022618
DOCK4	0.022560
CXCL10	-0.022559
RAB40B	-0.022537
TIFA	0.022496
ZNF426	0.022484
PLEKHB1	-0.022448
ARSB	0.022441
PRKAR2B	-0.022373
P2RY1	-0.022226
TSKU	0.022224
BOLA3	0.022180
SERPINE2	-0.022172
TDO2	0.022157
TRIM16	0.022129
ZNF503	-0.022108
NEK1	0.022088
RCN2	-0.022075
IFT80	0.022072
PFKM	-0.022060
MMP3	-0.022046
ARHGEF40	-0.022029
DMGDH	-0.021959
CD68	-0.021945
MGAT3	0.021941
HMGCR	0.021939
ABRACL	-0.021936
ERICH2	0.021913
HAO1	-0.021903
SNX10	0.021895
EBPL	-0.021895
CPT1B	-0.021882
SLC6A13	-0.021848
EMP1	-0.021840
ISG20	-0.021792
BCAT1	0.021782
UBE2C	0.021777
GBP2	-0.021764
DUSP6	0.021741
SLC7A14	0.021733
SREBF1	0.021701
TRIB3	0.021684
SGMS2	0.021669
P4HA1	0.021602
CHST14	-0.021591
TTLL1	0.021539
OAS1	-0.021507
NGF	0.021502
FDPS	0.021496
VKORC1L1	0.021463
SEMA6D	0.021445
TSPO	-0.021400
PLA2R1	0.021354
RPP38	-0.021336
VEGFB	0.021320
GPX3	-0.021291
FABP1	0.021283
TTC39A	0.021185
WARS2	-0.021171
GPT	-0.021167
BIRC7	0.021134
APOA2	-0.021130
ARG2	-0.021116
EFNA1	0.021114
CPT2	-0.021101
ABCC4	-0.021051
MBOAT1	0.021038
MGST2	-0.021035
FAM220A	0.021021
MLC1	-0.020986
FST	0.020985
SALL4	0.020983
BLVRB	-0.020979
SMIM1	-0.020962
GSTM1	-0.020953
CYB5A	0.020940
TCF19	0.020920
UHMK1	-0.020900
LTV1	0.020811
NUBPL	0.020798
GRIN2C	-0.020786
TATDN3	0.020776
AZGP1	0.020768
WTIP	0.020720
ARPC4	-0.020719
PKP3	-0.020655
FAM129A	0.020653
BCL2L14	-0.020650
ECI2	-0.020645
SNCG	0.020635
GSDMD	0.020618
SEMA4F	-0.020578
WIPI2	0.020560
GPD1L	0.020554
COX6A2	0.020499
SPATA33	0.020438
PDIA5	-0.020429
GCK	0.020407
IGFBP7	0.020323
GLUD1	-0.020297
CD3EAP	0.020290
CDKN3	0.020289
ALDH3B1	0.020234
VWA8	-0.020220
FABP4	-0.020207
CKAP4	0.020183
FILIP1L	0.020183
JAM3	-0.020176
MYL4	-0.020176
NMB	0.020156
EMILIN1	-0.020133
PHGDH	0.020133
TUBGCP3	-0.020120
ATP7A	0.020071
ACAT2	0.020063
PBX2	-0.020041
ASGR1	-0.020008
ACKR2	0.020006
LGALSL	0.020006
PCK1	0.020002
FOXO4	0.019988
LCAT	-0.019973
NEDD9	0.019961
YBX3	0.019941
GLS2	-0.019933
CDCA7	-0.019886
PMEL	-0.019882
CD44	0.019872
NPTXR	0.019868
CDK1	0.019862
ZNF395	-0.019860
SMYD2	0.019824
ZNF569	0.019805
CNKSR3	-0.019802
TMEM106A	-0.019795
VSIG10	-0.019753
STMN1	0.019695
GAL3ST1	0.019681
LAMA3	-0.019677
FGA	0.019674
PPIG	-0.019645
ACAT1	-0.019636
SH2D4A	0.019634
DEK	-0.019605
RASGRP4	0.019583
ALDH4A1	-0.019575
SMOC1	-0.019555
KCTD15	0.019553
SEPT4	0.019547
SOWAHC	0.019542
MTAP	0.019518
CIDEA	-0.019512
LCN2	-0.019488
SLC1A4	0.019457
DHFR	-0.019446
NDUFA4L2	0.019439
CYBB	-0.019389
LACTB	-0.019389
PSMB8	-0.019364
RRP15	0.019355
MYOF	0.019337
AGMO	-0.019333
ACADVL	-0.019327
USP1	0.019324
CLUAP1	0.019319
RNF6	0.019316
MYC	0.019310
CCDC66	0.019301
PCSK9	0.019284
TEKT1	-0.019267
DOK1	-0.019219
PDZK1	-0.019213
SPICE1	0.019204
ACOT4	-0.019199
CBR3	-0.019184
TMEM176A	-0.019135
TSPAN13	0.019132
VNN1	-0.019118
GUCY2C	0.019104
CLIP2	0.019078
FAM167B	-0.019072
POLL	0.019043
ABCB4	-0.019022
AGT	-0.019012
DHRS3	-0.019005
ARNT	-0.019004
RBP1	-0.018990
E2F5	0.018989
OSBPL3	0.018965
PIP5K1B	-0.018957
NCOA7	-0.018930
TRAPPC2	0.018923
PNO1	0.018919
MYLK	-0.018915
GSTZ1	0.018905
TMEM184C	0.018904
IFI44L	-0.018890
PIGL	0.018889
DIO3	-0.018880
DTX3L	-0.018878
CLCN6	-0.018857
IGSF11	-0.018847
POLR3G	-0.018803
MSH3	-0.018760
PPP3R2	-0.018754
SLC7A7	0.018730
TSPAN2	0.018713
DNAH17	0.018712
MMP19	0.018702
FAT4	0.018688
LPCAT1	0.018683
CCDC64	0.018652
CYP26A1	0.018627
IMPA2	-0.018617
PLK1	0.018579
TFPI	0.018552
PAK1	-0.018524
CMPK2	-0.018517
CEACAM1	0.018495
RCBTB1	-0.018487
DYRK1A	0.018485
ASPM	-0.018468
OLR1	-0.018459
HTR1D	0.018441
CLDN2	-0.018436
SLC46A3	0.018420
CCDC125	0.018419
ELOVL2	0.018382
HCK	-0.018381
YARS	0.018357
GRAMD1B	0.018355
COQ5	0.018312
DPT	-0.018296
PIR	-0.018290
CLIC1	-0.018284
NFAM1	-0.018260
CDHR1	0.018258