!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Mesalazine
!smiles	C1=CC(=C(C=C1N)C(=O)O)O
!drugbank_id	DB00244
!pubchem_cid	4075
!cell_type	Colon
!organism	human
!end_metadata
RPS4Y1	-0.170962
DEFA6	0.101811
EIF1AY	-0.100324
CLC	-0.081455
TXLNGY	-0.080142
XIST	0.079775
CYR61	0.076398
KDM5D	-0.074553
ERAP2	-0.073421
FOS	0.071511
USF1	-0.071488
FOSB	0.069339
INSL5	0.069311
EGR1	0.067494
DEFA5	0.064605
SPRR1B	-0.064565
SERPINA3	0.063955
RETNLB	0.063126
CXCL13	-0.061759
SAA4	-0.060157
BTNL8	-0.058975
PAX8-AS1	-0.058183
KLK10	0.057936
PTGS2	0.057812
S100A7	-0.057414
TFPI2	-0.053615
LTF	-0.053571
IL1B	0.053371
PCK1	0.053258
DSG3	0.053091
GZMK	-0.052706
BAMBI	0.052598
GPR171	-0.052087
PROK2	0.051662
CDH3	0.049708
DKK1	0.049215
SLC28A2	0.048988
SCNN1B	-0.046269
CCL21	-0.045739
TRIM40	0.045685
MS4A12	0.045462
VIP	0.045240
POMZP3	-0.045045
GIF	-0.044876
NR1H4	-0.044385
MMP10	-0.043980
CXCL8	0.043319
GREM1	-0.043307
C8orf4	0.043253
CA7	-0.042802
GPR18	-0.042738
IGHD	-0.042506
SLCO1B3	0.042388
ITK	-0.042091
MXRA5	0.041309
TM4SF20	0.041271
BEST2	-0.040917
IL2RB	-0.040855
IGFBP2	-0.039769
CD37	-0.039655
TYRP1	-0.039638
MT1M	-0.039517
ND6	0.039476
PCSK1	0.038976
CD52	-0.038674
CTGF	0.038134
SELL	-0.038078
HPGDS	-0.038029
PRAP1	-0.037929
APOD	0.037554
F3	0.037408
SPIB	-0.037191
CCL5	-0.036955
SLC16A9	0.036938
VSIG4	0.036888
SLC51A	0.036835
CD19	-0.036726
NR4A2	0.036713
CPB1	0.036484
PLA2G2D	-0.036329
NID2	0.036276
VSIG1	-0.036102
SFRP2	-0.035826
BEX5	0.035653
EYA2	-0.035361
REG1B	0.035176
TRBC1	-0.035130
GAS2L3	0.035127
PLAU	0.035061
ZFY	-0.034798
EGR2	0.034665
FAIM3	-0.034572
TPSB2	-0.033766
CCL22	-0.033731
MS4A1	-0.033462
LCK	-0.033197
NLRC3	-0.033055
PTX3	0.032980
IGLV4-60	-0.032629
MARCH2	-0.032611
TMEM220	-0.032550
STAT4	-0.032502
CCL11	-0.032426
LRMP	-0.032423
BTNL3	-0.032365
STMN2	0.032309
MAP4K1	-0.032222
CST7	-0.032185
DUSP4	0.032071
CD3D	-0.032061
MST1	-0.031987
KIT	-0.031804
SERPINB7	0.031681
BRINP3	-0.031613
IGLV3-19	-0.031345
MYL5	-0.030922
PLK2	0.030795
NPY1R	-0.030774
CORO1A	-0.030698
TARP	-0.030671
ELMO1	-0.030646
IER3	0.030446
LINC00520	0.030331
ALDH1A2	-0.030217
LINC01003	-0.030112
CYP4F11	-0.030038
SDR16C5	0.029918
JUN	0.029913
CPNE5	-0.029739
BTK	-0.029715
MS4A8	-0.029680
IGFBP3	0.029331
PHLDA1	0.029282
LOXL1	-0.029121
C10orf10	0.029081
MICB	-0.029010
RELT	-0.028982
ITLN1	-0.028977
SST	0.028975
ZBED2	-0.028891
CPXM1	-0.028852
CD7	-0.028821
LINC01279	-0.028806
CPA3	-0.028716
HLA-DQB1	0.028699
BANK1	-0.028672
IGKV3-20	-0.028635
PAIP2B	-0.028553
DUSP1	0.028547
TPSG1	-0.028526
CD2	-0.028491
TRDV3	-0.028484
CHMP4C	0.028430
RGS1	0.028420
CCR7	-0.028417
NPIPB15	0.028408
GABRP	-0.028387
PROS1	0.028282
PROCR	0.028090
BEST4	-0.027902
PSRC1	-0.027823
DDX3Y	-0.027817
MAP1B	0.027771
TLCD1	-0.027736
PTGDS	-0.027731
ZFP36	0.027586
KANSL1-AS1	-0.027584
CSRNP1	0.027569
ADH1C	-0.027476
IGKV1-5	-0.027351
CYP3A5	-0.027346
MEP1B	-0.027306
CEMIP	0.027183
ZFPM2	-0.027169
IL6	0.027043
ABHD14A	-0.027022
RAMP3	-0.026885
NBPF4	-0.026881
TRIM39	-0.026824
C1orf162	-0.026815
PLAT	0.026770
PPP1R15A	0.026723
HSPA6	0.026662
GCG	0.026656
ABI3	-0.026501
UGT2B17	-0.026478
CFI	0.026471
SNHG17	0.026228
GADD45A	0.026168
LILRA3	0.026131
CCDC107	-0.026101
TRAM2-AS1	-0.026079
ACSF2	-0.026055
PLTP	0.026049
KLRB1	-0.025923
TMEM56	-0.025890
SIK1	0.025870
RNF166	-0.025869
KRT12	-0.025835
SKAP1	-0.025791
TMEM176A	-0.025748
SECISBP2L	-0.025705
SGPP2	0.025599
CTSG	-0.025486
SULT1C2	0.025454
UHRF1	0.025449
AEBP1	0.025423
SOCS3	0.025390
ADA	-0.025382
STAP1	-0.025378
NKG7	-0.025368
IL32	-0.025366
PNPLA4	0.025351
NAPSB	-0.025324
GNA15	0.025300
SASH3	-0.025278
GIMAP4	-0.025273
PPP1R36	-0.025237
LAMP3	-0.025152
RGS18	-0.025142
CYP4F12	0.025126
RASGRP1	-0.025027
FUOM	-0.024997
PTGER4	0.024978
CCNO	0.024975
LINC00294	-0.024952
ZNF329	-0.024831
PPP1R18	-0.024809
IER2	0.024794
FAM78A	-0.024791
ZNF185	0.024771
HYAL1	0.024749
IGLV2-23	-0.024647
TRAT1	-0.024604
NEU4	-0.024481
ITGAL	-0.024416
HERC5	0.024362
ZNF322P1	-0.024339
AQP11	-0.024326
PNLIPRP2	-0.024299
C9orf91	-0.024189
CFH	0.024134
ERRFI1	0.024110
DEFB1	-0.024096
CXCL5	0.024078
CXCR2	-0.024052
KIF18A	0.024046
PKIB	-0.024039
SERPINE1	0.024007
CCL20	0.023976
CDC45	0.023887
CAPG	-0.023883
NMU	0.023863
CCR3	-0.023817
IGHV1-69	-0.023783
FAM149A	-0.023782
KRT6B	0.023776
YOD1	0.023766
CD160	-0.023740
HIST1H3H	-0.023716
TMEM39B	-0.023685
PLEKHG6	-0.023679
TRIM31	-0.023636
CD79A	-0.023607
P2RX5	-0.023606
FOXF2	0.023587
LOC153684	-0.023552
UCP2	-0.023495
HMOX1	-0.023440
AMN	-0.023415
LAMB1	0.023401
SLC7A11	0.023347
ABCA12	0.023323
AMFR	-0.023309
MEI1	-0.023271
EPHA2	0.023249
CCL4	0.023222
PAOX	-0.023197
PHF23	-0.023180
GOLGA7B	0.023175
LAG3	-0.023173
ZNF184	0.023137
BTLA	-0.023114
ZNF503-AS1	-0.023096
ADRA2A	-0.023093
S100A2	-0.022995
SLFN5	0.022977
LRRC66	0.022965
GBA3	-0.022937
PIK3CD	-0.022913
PPP1R14C	-0.022899
STX19	0.022847
NFE2L3	0.022812
PPL	0.022802
FCRLA	-0.022716
PTPRCAP	-0.022706
TMEM104	-0.022687
DOK3	-0.022669
CD38	-0.022661
PODXL	0.022596
ARRDC4	-0.022584
APOLD1	0.022540
SMIM6	-0.022531
FAM3B	-0.022526
BHLHE40	0.022517
MED22	-0.022439
ALOX5AP	-0.022432
CCDC125	-0.022329
TP53TG1	-0.022325
TNFRSF25	-0.022277
TUT1	-0.022271
TPRG1	0.022269
NCKAP1L	-0.022256
TIPARP	0.022230
IL1R2	0.022222
ECHDC3	0.022201
ARSE	0.022151
PRSS16	-0.022097
CDR2L	0.022048
SPON1	0.022043
MME	0.021986
ADAMTS1	0.021941
BAIAP2L2	-0.021938
CYBRD1	0.021931
OR7E14P	-0.021910
FAM98C	-0.021892
CIDEB	-0.021889
SAR1A	0.021826
TNIP3	-0.021809
SLC22A1	0.021793
LENG8	-0.021789
TNNI2	-0.021776
PCED1B	-0.021730
EVL	-0.021726
ACKR4	-0.021726
TMEM183A	-0.021711
CD27	-0.021705
SLC38A6	0.021703
KIAA0895	0.021604
ARHGAP9	-0.021578
REG1P	0.021558
PPM1M	-0.021553
ATL1	-0.021508
B4GALNT2	-0.021417
TMEM154	-0.021408
TFRC	0.021364
ANGPTL4	0.021332
TNFSF13B	-0.021309
CD83	-0.021309
TM4SF1	0.021302
PCDH18	0.021280
CTSLP8	0.021274
COLCA2	-0.021244
DNAJC6	0.021226
LCP1	-0.021215
COL5A1	0.021137
IL18RAP	0.021122
PDGFD	0.021084
GBP5	-0.021083
MATN2	0.021073
MDK	-0.021070
CAV1	0.021069
S100A9	-0.021038
INHBA	0.021030
PLA2G4F	0.021018
SLA	-0.020993
SHANK3	-0.020903
GMFG	-0.020900
HBEGF	0.020886
LIF	0.020858
NELL2	-0.020858
RELB	-0.020850
DNAJB2	-0.020850
TBC1D10C	-0.020824
MMP9	0.020822
RGS2	0.020735
CBFA2T3	-0.020688
SLC16A4	0.020688
ARMCX1	0.020636
HDHD1	0.020636
KLK11	0.020587
SYNGR3	-0.020586
CLDN8	-0.020585
CD3E	-0.020583
CHRDL2	-0.020569
HLA-DOB	-0.020516
CR2	-0.020507
CA4	-0.020482
GRINA	-0.020482
CEMP1	0.020481
LOC285628	-0.020469
MAFF	0.020447
LOC101927934	-0.020431
SCGN	0.020385
SELPLG	-0.020377
RSPO3	-0.020355
IGHM	-0.020352
TLR2	0.020345
FOXQ1	0.020341
DENND1C	-0.020327
HOXD10	-0.020315
METTL21A	-0.020307
NAMPT	0.020278
BCL7C	-0.020262
GCOM1	-0.020244
GPX3	0.020240
ARL15	-0.020231
MGC27345	0.020230
LINC00668	0.020206
CIPC	-0.020197
TRAC	-0.020180
GJA1	0.020154
HSD11B1	0.020108
ITM2A	0.020092
ATRIP	-0.020044
GNAI2	-0.020012
NR1H3	-0.020011
ATG14	-0.020000
FCRL3	-0.019992
CTAGE9	0.019941
LTBP2	-0.019900
LRRC37A2	-0.019898
IFFO1	-0.019886
GAPT	-0.019865
CLIP2	-0.019768
DDX60L	0.019723
P2RY14	-0.019685
PASK	-0.019684
JUNB	0.019676
GFI1	-0.019664
IL22	0.019646
ZNF764	-0.019643
LOC100131564	-0.019638
TPSAB1	-0.019633
SLC44A5	0.019606
ST6GALNAC2	0.019604
CRMP1	0.019592
CLDN2	-0.019560
MYO1G	-0.019560
C16orf74	0.019536
HCAR3	0.019513
FRZB	0.019512
IGSF6	0.019501
TLR10	-0.019496
FAAH	-0.019494
DENND3	-0.019471
STC1	0.019415
LSP1	-0.019380
ZNF580	-0.019375
FAM109B	-0.019365
RAC2	-0.019362
PNPT1	0.019359
C7orf31	-0.019327
ARHGAP4	-0.019323
BIN2	-0.019309
ART3	-0.019270
CD69	0.019269
SEPT6	-0.019248
NUDT2	-0.019248
RUNX3	-0.019248
TFPT	-0.019243
TIGD2	0.019232
YBX2	-0.019197
GPR37	0.019171
SPARCL1	0.019170
ZNF133	-0.019167
SDC2	0.019158
ZAP70	-0.019133
CCNJL	-0.019117
ARHGEF9	-0.019109
C10orf2	0.019091
SAMD5	0.019082
MAFB	0.019040
WNT5A	0.019011
TSPYL5	-0.019010
PLA2G3	0.019008
CD151	-0.018994
CHAC1	-0.018975
HES6	-0.018971
MFSD9	-0.018955
REG3A	0.018952
CD248	-0.018947
GOLGA4	0.018923
DOCK10	-0.018912
SPARC	0.018907
GUCA2B	-0.018864
ABHD14B	-0.018804
GIPC2	0.018801
SCAP	-0.018788
RSPH1	0.018777
SERPINB4	-0.018769
CCDC58	-0.018762
BAG3	0.018751
CTHRC1	0.018727
C2CD4A	0.018707
GRAMD2	0.018706
ARRB2	-0.018706
SOWAHC	0.018642
NUDT11	0.018639
SPRY2	0.018631