!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Ursodeoxycholic acid
!smiles	CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
!drugbank_id	DB01586
!pubchem_cid	31401
!cell_type	colon epithelium
!organism	mouse
!end_metadata
FXYD4	-0.160825
HIST1H2BI	-0.142685
TGM3	-0.120039
IER2	-0.118463
SPINK1	0.114995
WFDC2	-0.113063
ATF3	-0.111512
H1F0	-0.106127
NR4A1	-0.103502
HSPA8	0.100465
TXNIP	-0.100253
SYCN	-0.098758
REG4	0.097489
IFIT1B	-0.096375
DMBT1	-0.095147
ZFP36	-0.093237
SEPP1	0.090839
CYP2C18	-0.090271
RHOB	-0.089983
AREG	-0.089001
HSPA5	0.088885
AQP8	0.088376
SLPI	0.087615
HIST1H1C	-0.087169
KRT18	-0.084586
JUN	-0.082389
CYCS	0.081258
HSP90AA1	0.080260
USMG5	-0.079040
CA4	-0.078914
HSPD1	0.078740
HSP90AB1	0.078604
DYNLL1	0.077727
BTG2	-0.076831
EGR1	-0.075203
NUPR1	-0.073572
IL18	-0.071982
UBC	-0.070501
LDHA	0.069936
SLFN12L	-0.068755
CA2	-0.068655
KLF4	-0.068235
UQCRHL	0.067975
ABCB1	-0.067105
MFSD4	-0.065906
S100A10	0.065471
S100G	0.064606
KLF6	-0.063070
INSL5	0.062144
GSDMC	-0.061429
RSAD2	-0.061389
SLC20A1	-0.061257
PSMB7	0.061193
TPI1	0.061019
LGALS9B	-0.060937
HMGCS1	-0.060456
CLDN8	-0.060332
CALR	0.059372
OAS1	-0.058415
PRDX6	-0.058277
TMIGD1	0.058267
WBP5	-0.057766
CELA1	-0.057680
MANF	0.057445
GAS6	-0.057197
OAT	-0.056268
HBEGF	-0.055947
SGK1	0.055656
SLC26A3	-0.055583
SLC5A8	-0.055347
PFN1	0.055152
TMEM30B	-0.054416
S100A14	-0.054205
PMP22	-0.053826
HSPH1	0.053612
SLC37A2	-0.053172
MDH2	0.051911
PTP4A2	-0.051906
KRT19	0.051105
FAM162A	0.050609
IFIT2	-0.050500
RETNLB	0.049811
DUSP1	-0.049709
RASD1	-0.049434
IRF1	-0.049396
DNAJA1	0.049120
FOS	-0.048437
PARP12	-0.048050
MKI67	-0.048040
PGAM1	0.047907
GPI	0.047309
H2AFV	-0.046977
ITIH5	-0.046398
MRPL12	0.045244
PYY	0.045142
CCNI	-0.044923
CD9	-0.044719
NDUFB10	0.044358
CRELD2	0.044282
JUNB	-0.043723
SLC6A14	-0.043651
TFF3	-0.043521
SCD	0.043359
PGK1	0.043340
GPX2	0.043266
HSP90B1	0.042514
TMEM45B	-0.042275
CRIP1	-0.042100
SLC25A3	-0.041986
PSMC4	0.041859
ANXA1	0.041729
GAPDH	0.041561
GUCA2A	-0.041498
CHORDC1	0.041169
EMP1	0.040979
SMPDL3A	-0.040907
MUC13	-0.040742
PIGR	-0.040462
ACSM3	-0.040321
AGR2	0.040320
THBS4	-0.040152
TMA7	0.040087
IFIH1	-0.039912
EIF5A	0.039761
SNX3	0.039658
P4HB	0.039370
ZG16	0.039356
CXCL10	-0.039217
TM4SF20	-0.039146
PGLYRP1	0.038987
NDUFA11	0.038970
COX4I1	0.038862
PHLDA1	-0.038859
B2M	-0.038766
THBS1	-0.038707
CYC1	0.038401
FAM3D	-0.037792
CLCA1	0.037753
CEPT1	-0.037723
ZFAND5	-0.037567
MIF	0.037530
ID1	-0.037529
FHL1	0.037414
NME1	0.037231
IFIT3	-0.037196
ERRFI1	-0.036822
MAPK13	-0.036534
PCBP1	0.036248
CLDN23	-0.036178
EIF4A1	0.036021
PSME2	-0.035723
JUND	-0.035289
KLF5	-0.035254
IVNS1ABP	-0.034824
PROM1	0.034645
CCND2	-0.034573
TIMM23	0.034440
NT5C3A	-0.034253
UQCR11	0.034035
CCT5	0.033958
CHMP4B	-0.033910
SAA1	0.033395
SERP1	0.033320
FCGBP	0.033293
DIO1	-0.033153
EPPK1	-0.032973
GLUL	-0.032785
ABCG2	0.032626
SHISA5	-0.032573
CCT6A	0.032535
UPP1	-0.032520
RHPN2	-0.032483
DDC	0.032474
IFI30	-0.032211
GADD45A	-0.032095
TCP1	0.031725
FKBP4	0.031649
RAN	0.031593
USP18	-0.031517
KRT8	-0.031456
ANXA3	0.031455
CACYBP	0.031419
EDN2	-0.031266
PCBP2	-0.031156
PARP9	-0.031101
IRF7	-0.030961
CLINT1	-0.030947
CTSS	-0.030765
CCNL1	-0.030677
SMAGP	-0.030510
LGALS3BP	-0.030449
RPS3	-0.030260
RPL26	-0.030160
CD177	0.030110
HSPE1	0.029984
CHCHD10	0.029967
COX5A	0.029915
RBM3	-0.029893
ENO1	0.029847
CYP4F12	0.029833
ALDH1B1	-0.029784
RNASEL	-0.029761
SLC9A3R1	-0.029645
GSN	-0.029610
SLC26A2	-0.029481
NET1	-0.029311
SCAMP1	-0.029264
SLC35B1	0.029223
C20orf24	0.029189
MEP1B	0.029187
YBX3	0.029180
UBALD2	-0.028909
SLC16A1	-0.028895
ARL4A	-0.028835
IRGM	-0.028821
STIP1	0.028792
WSB1	-0.028780
PSME1	-0.028768
ELF3	-0.028699
AOC1	-0.028681
AHSA1	0.028643
HES1	-0.028592
ETS2	-0.028479
PDZK1IP1	-0.028251
SGK2	0.027959
NDUFA1	-0.027873
EEF2	-0.027829
ACTA1	-0.027773
RPS8	0.027622
RPL27A	-0.027578
RTP4	-0.027305
PDE9A	0.027299
LYPD8	-0.027275
C1QBP	0.027167
SKP1	0.027107
PAIP2	-0.027098
SLC6A8	-0.027017
SELM	-0.026960
MS4A8	-0.026916
TMBIM1	-0.026899
SMAD4	-0.026830
FAM134B	-0.026654
ATP5G3	0.026389
FKBP5	0.026381
SAMM50	0.026276
IFITM3	-0.026241
SNX2	-0.026163
COX7A2	0.026135
LAPTM4A	-0.026077
SEMA4G	-0.026065
PLGRKT	-0.026010
FAU	-0.025951
EEF1G	0.025804
PSMD2	0.025741
MIEN1	0.025699
DNAJB1	-0.025654
APOC2	0.025652
ANXA4	0.025614
DYNC1H1	-0.025490
ST14	-0.025437
BMP2	-0.025384
PPTC7	-0.025363
ADH1C	-0.025361
TAX1BP3	0.025324
DPEP1	0.025319
ATP6V0C	-0.025308
BAG1	-0.025286
METTL7B	0.025258
UQCRC1	0.025191
CREB3L1	-0.025151
FUT8	-0.025094
WASF2	-0.025068
CCNG2	-0.025057
CSRP2	-0.025047
UQCRFS1	0.024959
ABCD3	0.024945
EDF1	0.024942
RAB6A	-0.024898
GBP2	-0.024859
POF1B	-0.024791
COX6A1	-0.024699
ACOX1	0.024620
TFRC	0.024550
SET	0.024536
SULT1C2	-0.024442
SELENBP1	-0.024418
TRIM25	-0.024331
COX7A1	-0.024252
PTPRF	-0.024176
NDUFS3	0.024163
EIF2S2	-0.024149
SYAP1	-0.024040
GPX4	0.024007
CLK1	-0.023987
ARPC2	-0.023897
PERP	-0.023836
SDF2L1	0.023775
PPP2R5A	0.023746
RPLP0	0.023696
SPTBN1	-0.023543
ATP5G1	0.023496
UQCRC2	0.023431
MRPS34	0.023381
RPL6	0.023308
ANO1	-0.023303
CYP2S1	-0.023291
TIMM13	0.023261
OASL	-0.023255
SUCLG1	-0.023216
PTGES3	0.023191
SLC12A2	-0.023009
EIF4A2	-0.022979
MDH1	0.022956
UAP1	-0.022942
PLAC8	-0.022894
PARP14	-0.022787
TAPBP	-0.022754
FAM107B	-0.022710
CMPK2	-0.022618
EIF3G	0.022593
SAR1B	0.022531
PSMD6	0.022510
VCP	0.022494
COA3	0.022449
TMX2	0.022403
ST3GAL4	0.022384
CTSE	-0.022367
RPL7	0.022336
ELF1	-0.022334
HIST3H2A	-0.022326
TMEM126A	0.022239
PSMB3	0.022229
MSMO1	-0.022173
SLMO2	0.022090
SERPINB1	-0.022071
DBP	-0.022050
CYFIP1	-0.022044
GCSH	0.022026
HSD11B2	0.021990
DRAM2	-0.021955
KLF9	-0.021951
SAT1	-0.021948
APPL2	-0.021930
CDH17	0.021929
FKBP9	-0.021922
TRIM2	-0.021904
ARHGAP21	-0.021888
STAT1	-0.021871
ODC1	0.021831
MYO1D	-0.021729
MTM1	0.021725
DUSP6	-0.021711
MYH9	-0.021683
MID1IP1	0.021668
SLC44A4	-0.021620
FABP6	0.021555
CASP1	-0.021535
RARS	0.021529
PELI1	-0.021474
CLPTM1L	0.021422
CD74	0.021345
CYBA	-0.021333
TRIM31	-0.021280
TSPAN13	-0.021267
EDN1	-0.021263
NDUFC1	0.021215
DDIT4	0.021205
GSTM1	-0.021146
CLDN3	-0.021122
OXCT1	-0.021073
TAX1BP1	-0.021003
RPL10	0.020930
ATP2A3	-0.020917
MBOAT1	-0.020891
OSBPL2	-0.020854
PSMC2	0.020816
CDHR5	-0.020802
ACSS2	-0.020779
NOP10	0.020761
HID1	-0.020684
ALDOB	0.020646
CHCHD4	0.020639
STARD4	-0.020604
MPC2	0.020543
TMEM147	0.020515
CYR61	-0.020513
GALE	0.020461
NADK	0.020438
PGP	0.020384
RPS15A	0.020349
NHP2	0.020270
RPL24	-0.020208
ENO3	-0.020183
MRPL20	0.020120
MARCH7	-0.020100
SDCBP2	0.020085
BSPRY	-0.020059
TMBIM6	-0.020036
BHLHE40	-0.020012
ALDOA	0.020011
HNRNPD	-0.019982
SPCS3	0.019960
RFK	0.019908
RHOA	-0.019817
VDR	-0.019793
UBE2C	-0.019779
ATF4	-0.019776
TUBA4A	0.019774
ACTN4	-0.019635
PSMD14	0.019635
POLR2K	0.019628
CANX	0.019616
ACLY	-0.019611
VASP	-0.019606
PIM3	-0.019602
PSMB9	-0.019601
ATP5F1	0.019588
SLC35A1	-0.019579
TMEM14C	0.019553
TMCC3	-0.019545
DSTN	0.019495
CALML4	0.019476
CISD1	0.019434
DSP	-0.019420
HNRNPAB	0.019394
PSMB8	-0.019345
IDH1	0.019318
PHB2	0.019271
FBL	0.019235
PNPO	-0.019157
SLC34A2	0.019138
ARFGAP3	-0.019087
OSTC	0.019079
ASAH1	-0.019074
FOXA1	-0.019024
MAOA	0.019019
CCT2	0.018973
CLDN4	-0.018941
ABRACL	-0.018919
SPCS2	0.018918
PSMA3	0.018881
ATP5J	0.018869
DBI	0.018796
EIF4G2	0.018770
SMC4	-0.018768
BSG	0.018740
TUBA1B	0.018733
GSTM3	-0.018716
SLC25A24	-0.018715
ERBB3	-0.018712
MGST3	0.018702
CD2AP	-0.018699
TSPAN7	-0.018515
HNRNPC	0.018490
CCT7	0.018487
UCP2	-0.018461
SYPL1	-0.018459
ACTR3	0.018444
TFG	0.018425
CHDH	-0.018412
F11R	-0.018246
PPDPF	0.018239
YWHAZ	0.018226
GNPNAT1	-0.018213
TRIB1	-0.018157
LSM3	0.018151
RDX	-0.018140
VMP1	-0.018062
NDUFAB1	0.018046
SASH1	-0.018038
CCNB2	-0.018036
PGD	0.018026
PRELID1	0.017981
ABAT	-0.017981
P2RX4	-0.017955
NDUFA8	0.017934
PLLP	-0.017878
ST6GALNAC6	0.017864
NAA38	0.017857
SELT	0.017856
DEGS2	0.017812
POLR2F	0.017805
FABP2	0.017761
LSR	-0.017723
CPT1A	-0.017703
PHB	0.017689
CLCN2	-0.017685
SRM	0.017671
NARS	0.017669
ESRP1	-0.017634
YWHAQ	0.017584
MGAT4C	0.017575
PYGB	-0.017521
RPN1	0.017463
GNAI2	-0.017452
RPL38	0.017410
RPL23	-0.017373
CDK1	-0.017307
LYPLA1	0.017293
LAD1	-0.017278