!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Curcumin
!smiles	COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
!pubchem_cid	969516
!cell_type	HL-60 leukemia cells
!organism	human
!end_metadata
PRTN3	-0.124621
IGLL1	-0.112351
LY96	0.111231
FTH1	0.088752
HMOX1	0.080705
SERPINB10	-0.079015
BLVRB	0.075703
SAT1	0.074230
ANXA2	0.073082
MPO	-0.072481
PIR	0.066769
MS4A3	-0.066135
ELANE	-0.062303
YPEL5	0.061547
FTH1P5	0.056729
IFT57	-0.055806
MLC1	-0.055336
DENND4B	0.054564
CCL2	0.052949
NQO2	0.052940
MYC	-0.050426
PUS7	-0.049787
CCDC86	-0.048525
PRG2	-0.048174
DNAJC12	-0.048109
DLEU1	-0.047939
SPP1	0.047430
GAL	-0.046434
AZU1	-0.046221
MRPL4	-0.045752
DCXR	-0.045426
ANKRD55	-0.045335
CLC	-0.045152
GCLM	0.044903
ANXA1	0.044420
P2RY2	-0.044278
ABHD3	0.044108
MEST	-0.044006
LGALS1	0.043848
TRDV3	-0.043824
SRM	-0.042913
PMS1	-0.042755
MCM7	-0.042639
SLC7A11	0.042347
EBNA1BP2	-0.042014
RPIA	-0.041519
NFKBIA	0.041321
NRIP3	0.040984
FAM216A	-0.040686
ANKRD27	-0.040372
HEATR2	-0.039591
LPL	-0.039467
BEX1	-0.039292
IPO4	-0.038782
PFAS	-0.038666
PDZD8	-0.038666
LASP1	0.038652
QDPR	-0.038394
MRTO4	-0.038394
EXOSC5	-0.038315
FIBP	-0.038029
CTSG	-0.037897
RNASE2	-0.037885
CIB1	-0.037729
NOC3L	-0.037688
GPD1L	-0.037676
NEFH	-0.037625
MTHFD1	-0.037546
PNP	-0.037443
NQO1	0.037367
TXNRD1	0.037350
PRMT1	-0.037288
RABEPK	-0.037274
ASUN	-0.037144
CCL4	0.037101
TNF	0.036971
GSR	0.036946
ALOX5AP	0.036907
MACROD1	-0.036739
BAHCC1	-0.036671
C1orf54	0.036595
DDX10	-0.036479
ME1	0.036478
FUT4	-0.036374
C1QBP	-0.036167
WBSCR22	-0.035997
SDCBP	0.035995
SQRDL	0.035800
PSAP	0.035657
XYLT1	-0.035644
WDR3	-0.035358
CYB5R1	0.035240
GLIPR1	0.035228
SLC43A3	-0.035164
PRMT3	-0.035007
RIT1	0.034953
MTR	-0.034863
SEH1L	-0.034759
CARS2	-0.034523
SLC5A6	-0.034484
PCID2	-0.034395
MARCKSL1	-0.034096
UNG	-0.034017
SMS	-0.033993
MAD1L1	-0.033798
NHP2	-0.033796
PEBP1	-0.033757
WDR18	-0.033730
SERINC5	-0.033626
HSPA14	-0.033536
LTB	0.033299
TPM4	0.033279
TNFAIP8	-0.033086
HCK	0.033041
NUP155	-0.033041
TIMM10	-0.033027
TFE3	0.032909
TRAP1	-0.032871
MYD88	0.032859
RUVBL2	-0.032859
LPXN	0.032843
NCF2	0.032506
MRPL24	-0.032376
MDN1	-0.032350
FARSA	-0.032221
NME1	-0.032220
SACS	-0.032206
PRDX4	-0.032104
MT2A	0.032102
TCFL5	-0.032064
SEL1L3	0.032031
ZNF222	0.031943
FABP5	-0.031934
TMEM147	-0.031894
ATP5G1	-0.031750
FTL	0.031744
NARS2	-0.031634
BZRAP1	-0.031581
CEBPB	0.031541
NDUFAF4	-0.031504
LDHA	-0.031113
CAD	-0.031060
POLR2I	-0.031049
PSMG1	-0.031023
GPR125	-0.030956
BCL11A	-0.030935
HIST1H2BK	0.030930
FKBP4	-0.030814
TFB2M	-0.030788
PRKCB	0.030663
PTPRC	0.030603
DPH2	-0.030514
ACAT1	-0.030386
IMP4	-0.030332
TFRC	-0.030246
BIN2	0.030188
RUVBL1	-0.030138
SLC2A3	0.029997
NIP7	-0.029851
C6orf48	0.029849
PLP2	0.029705
GBP2	0.029693
PTGER2	-0.029667
PHB	-0.029662
NFIL3	0.029614
CD53	0.029379
NPM3	-0.029317
MAP1LC3B	0.029282
STOML2	-0.029225
ARFGAP3	0.029212
WDR12	-0.029212
DPAGT1	-0.029081
TYROBP	0.029068
MAK16	-0.028991
IFRD2	-0.028952
TMCO6	-0.028898
ATP6V1A	0.028898
VIM	0.028896
DDX21	-0.028770
SUPV3L1	-0.028680
HSPE1	-0.028652
TRIP13	-0.028600
IARS2	-0.028482
ZNF593	-0.028470
C10orf2	-0.028456
NEU1	0.028442
PSTPIP2	-0.028442
ILF2	-0.028328
FAR2	-0.028261
ABHD14A	-0.028221
SLC27A2	-0.028216
PYGL	-0.028170
COQ10B	0.028117
TMEM39A	0.028117
VKORC1	-0.027975
PMAIP1	0.027966
TIMM13	-0.027961
TTC27	-0.027935
CFD	-0.027777
GRPEL1	-0.027716
GAR1	-0.027675
PTPRE	0.027649
PSMC4	0.027622
ACTL6A	-0.027610
YWHAH	-0.027429
CCND3	0.027336
PA2G4	-0.027330
KBTBD11	-0.027322
TFDP2	-0.027310
SCO2	-0.027284
GSPT1	-0.027263
RCBTB2	0.027245
KIAA0020	-0.027220
DCTPP1	-0.027166
PAXIP1	-0.027166
SERBP1	-0.027157
SRPX	-0.027088
CA8	-0.027038
TES	0.027036
GAB2	0.027022
SLC25A20	0.027010
NDUFV1	-0.026854
PSMB4	0.026852
TAF9	-0.026822
PSMD1	0.026801
RABAC1	0.026748
NAA15	-0.026724
PGD	0.026695
ADI1	0.026671
SMCO4	0.026565
TUBB2A	0.026555
BZW2	-0.026555
ARHGAP25	0.026554
UFD1L	0.026541
HOXA1	0.026527
CD3EAP	-0.026501
ANPEP	0.026501
GABARAPL1	0.026450
PUS1	-0.026308
LAS1L	-0.026269
CXCR4	-0.026260
SARAF	0.026255
ACBD3	0.026229
PBK	-0.026217
PRPS2	-0.026215
SH3BP5	0.026177
EMP3	0.026071
RRP9	-0.026059
EIF1AX	-0.025955
CAPN2	0.025942
GLRX5	-0.025929
SLC39A4	-0.025916
CCNB1	-0.025892
LGALS3	0.025772
SMARCC1	-0.025673
TRIM5	0.025564
SLIRP	-0.025500
PSMB8	-0.025358
AMD1	-0.025344
PSMB6	0.025264
MFSD10	-0.025250
PWP2	-0.025174
MPV17	-0.025162
CECR5	-0.025136
CDC45	-0.025122
GRAMD4	-0.025122
TSPAN13	0.025108
PSMD2	0.025108
BCS1L	-0.025095
PRKRA	-0.025086
UROS	-0.025032
C12orf29	-0.024979
FAM46A	-0.024939
KCTD7	0.024913
SSH1	0.024907
THYN1	-0.024862
EIF4EBP1	-0.024862
IFRD1	0.024854
TNFAIP2	0.024842
MRPS30	-0.024837
APEH	-0.024823
MT1X	0.024776
GINS2	-0.024758
TRIAP1	-0.024693
ITM2A	-0.024680
MIF	-0.024667
HILPDA	-0.024667
MGLL	-0.024587
TMEM123	-0.024577
KRCC1	0.024563
SLC25A15	-0.024537
FAM35A	-0.024535
NEK4	-0.024509
CETN3	-0.024483
SLC38A10	-0.024469
CCND2	-0.024458
PLAC8	-0.024407
SLC4A2	-0.024407
RGS2	0.024404
ADSS	-0.024367
WDR26	0.024312
GNL2	-0.024277
DDX46	-0.024197
HS1BP3	0.024158
SQSTM1	0.024125
LAP3	-0.024030
ACN9	-0.024002
SLC29A1	-0.023957
MICAL2	-0.023932
LYN	0.023909
ATP5D	-0.023905
HEATR1	-0.023892
FAHD2A	-0.023873
KATNB1	-0.023801
MRPL16	-0.023782
TMEM33	-0.023756
MPZ	0.023730
PPP1R14B	-0.023716
AK2	-0.023710
URB2	-0.023688
TUBA4A	0.023688
NR2F2	-0.023663
ADSL	-0.023651
SIGMAR1	-0.023625
CARM1	-0.023598
DBF4	-0.023560
SSB	-0.023534
RFC3	-0.023515
NAT10	-0.023442
CCL20	0.023363
UNKL	0.023351
SYNCRIP	-0.023319
VARS	-0.023318
POLR2H	-0.023286
NEK7	0.023272
CHPF2	0.023253
VAMP8	-0.023247
UBE2N	-0.023230
ACYP2	0.023219
MIPEP	-0.023175
TMEM41B	0.023149
SREK1	-0.023142
ODC1	-0.023117
APOL2	0.023110
POLR1E	-0.023091
CTPS1	-0.023077
NELFCD	-0.023051
RNMTL1	-0.023037
S100A11	0.022979
UCK2	-0.022975
LSM7	-0.022961
HSD17B10	-0.022961
SAC3D1	-0.022947
NINJ1	0.022907
CCNH	-0.022845
KIAA0930	-0.022842
HADH	-0.022826
MRPL3	-0.022805
CKS2	-0.022805
NUCB2	-0.022791
CITED2	-0.022772
SMYD3	-0.022765
MZB1	-0.022751
LRP10	0.022738
NCL	-0.022661
STAR	-0.022661
GBAP1	0.022647
OXCT1	-0.022621
PIH1D1	-0.022621
TM7SF3	-0.022596
RSAD1	-0.022582
PFDN2	-0.022545
NOP16	-0.022508
ITGA4	-0.022492
ATP5J2	-0.022491
C21orf59	-0.022479
FCGR1B	-0.022479
POLD2	-0.022454
PHF10	-0.022440
SNRPA1	-0.022344
BOP1	-0.022270
MAD2L1	-0.022258
ABCE1	-0.022257
SSRP1	-0.022205
STRA13	-0.022166
IFT88	0.022166
TOP2B	-0.022166
IFITM1	-0.022160
GTF3A	-0.022153
C20orf24	0.022152
DAZAP1	-0.022126
ZNF652	0.022050
ESYT1	-0.022010
CMTM6	0.022010
APEX1	-0.021998
DNAJA3	-0.021996
EVI2A	0.021943
TRAPPC2	-0.021904
MRPL12	-0.021880
ABCC4	-0.021880
CD320	-0.021854
ATR	-0.021853
PARP4	0.021840
SH3GLB1	0.021817
QTRT1	-0.021814
MRPL15	-0.021738
NUDT1	-0.021710
LMNA	0.021673
DDT	-0.021634
HECA	0.021592
CORO1B	-0.021587
ARF4	0.021585
MRPS2	-0.021568
HSPD1	-0.021561
TMEM251	-0.021542
LOC440434	0.021541
GLRX	0.021494
IMPA2	-0.021463
ENOPH1	-0.021399
TMEM109	-0.021385
AASDHPPT	-0.021372
FAM111A	0.021371
CD81	-0.021333
SMPDL3B	-0.021319
PLEK	0.021306
TOMM40	-0.021268
PITPNC1	-0.021255
SEC31A	0.021253
FAM173A	-0.021243
UQCR11	-0.021241
IL2RG	-0.021231
COQ2	-0.021229
UBA2	-0.021215
NTHL1	-0.021203
CLU	0.021202
RCN2	-0.021157
SYNRG	0.021097
U2SURP	-0.021085
RASSF2	0.021071
RNASET2	-0.021066
ARMCX3	0.021059
MTCH2	-0.021059
PPP1R11	0.021057
LGALS8	0.021047
SLC22A4	-0.021045
TFB1M	-0.021019
BSCL2	0.021005
VCP	0.020987
LITAF	0.020966
OGFOD1	-0.020929
UQCRC1	-0.020903
VPS39	0.020889
ANXA5	0.020887
PRMT5	-0.020877
NOC4L	-0.020862
ZDHHC3	-0.020838
MRPS7	-0.020787
NOL11	-0.020759
TIPIN	-0.020759
DDX41	-0.020733
CTDSP1	-0.020720
MOSPD3	-0.020720
FASTKD1	-0.020720
ZNF331	-0.020720
TRIP4	0.020706
C21orf33	-0.020662
CCR1	0.020654
TRIB1	-0.020629
CYCS	-0.020604
KIAA0232	0.020590
MT1HL1	0.020590
TRAM1	0.020542
CAPG	0.020536
NUP37	-0.020527
CSNK2A2	0.020483
PPM1G	-0.020448
S100A8	0.020447
DNPH1	-0.020434
GNL3	-0.020434
CNBP	-0.020434
MSRB1	0.020420
MCM6	-0.020420
BCKDHA	-0.020408
OSTF1	0.020406
UBXN4	0.020376
PSMC2	0.020348
CCT2	-0.020337
UBE2G2	-0.020291
RXRA	0.020291
GLOD4	-0.020278
APITD1	-0.020264
TUBA1A	0.020262
S100A4	0.020250
NOLC1	-0.020208
MPHOSPH6	-0.020134
CD58	0.020123
DUT	-0.020122
ATP5B	-0.020108
SRI	-0.020108
STUB1	-0.020108