!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 12 Hour
!organism	rat
!end_metadata
GLUL	0.309974
RRAD	0.251794
TRIM54	0.209801
ATP2A1	0.177299
COX2	-0.171615
NDUFB9	-0.140228
HSPB1	0.139030
MGP	0.137528
MPC1	-0.124845
UBC	0.121974
CST3	0.120836
ACTG1	-0.109610
MYL2	-0.107750
TXNIP	0.107722
PDK4	0.106459
HSPB6	-0.102287
MYL12B	-0.101988
ACTN2	0.099909
CKM	0.098751
PYGM	0.097505
TSC22D1	0.094248
CYC1	-0.092745
TUBA1A	-0.089045
MYBPC1	0.088479
CRYAB	-0.085770
PKM	0.084386
CTSV	0.084179
G0S2	0.083919
RPL22	-0.082363
AMPD1	-0.080930
TNNT3	-0.080487
EIF4A2	0.080185
NDRG2	0.077157
HP	0.077000
ASB2	-0.076941
ACTB	-0.075759
CKMT2	0.074994
EIF4EBP1	0.074702
PPIA	-0.072961
ACADM	0.072936
MYF6	0.071009
COX7A2	-0.070539
SVIL	0.065728
MYBPH	-0.065060
PABPC4	0.065047
NR4A1	-0.064524
MYH7	0.064135
TUBA1B	-0.064082
ATP5B	0.062423
NDUFB4	-0.062387
PSME4	0.062058
MYBPC2	0.061563
PSAP	0.060766
COX3	-0.060467
KLHDC3	0.060420
ACTA1	0.059363
LUM	-0.058538
SLC25A3	-0.058085
ENO3	-0.057989
NDUFB2	-0.057399
ALDOA	0.056970
DDX3X	0.055771
GOT1	0.055760
MAP1LC3B	0.055476
CACNG1	-0.054514
PFKM	0.054166
CD36	0.054087
LDHB	-0.054069
OAZ1	-0.053904
SDHA	0.053589
NDUFA4	-0.052462
CHRNA1	-0.052058
NDUFB3	-0.051578
NEU2	-0.051004
LGALS1	-0.050903
ATP5F1	-0.050881
LYZ	0.050306
TMA7	-0.049297
FTH1	0.048827
TNNC2	0.048678
RPL26	-0.048650
ACAA2	0.048380
TPI1	0.048127
ATP5H	-0.048119
FAU	-0.047895
CYCS	-0.047792
NDUFS7	0.046583
XDH	0.046365
MAPK14	0.046345
YWHAH	0.046028
CSRP3	0.045584
PCBP4	0.045518
TNNI2	0.045412
NR1D1	-0.045156
CTSS	0.045094
SCHIP1	0.045020
DES	0.044997
RPL4	-0.044936
GPX1	-0.044211
RPS27L	-0.044173
ND5	0.043697
NR1D2	-0.043622
MDH2	0.043608
MAPK6	-0.043169
COX7B	-0.042381
CYTB	-0.041659
AK1	-0.041571
FLNC	0.041544
IFITM3	0.041198
CBFB	-0.040738
RPL39	-0.040564
PSMD11	0.040266
RPL3L	-0.039917
JPH2	-0.039331
CEBPB	0.039313
AKR1A1	-0.039003
RPS17	-0.038688
COL1A1	0.038603
KLHL41	-0.038195
GPX3	0.037324
MYH1	0.037307
POMP	-0.037282
AHNAK	0.037236
ATP6	0.037220
HPX	0.036759
RPL24	-0.036524
FABP3	0.036489
TOMM20	-0.036401
PDHA1	0.036187
EIF2B4	0.036095
MYH6	0.036046
MGST3	-0.035609
RPL10A	0.035418
CPT2	0.035263
MAP1LC3A	0.035190
TECR	-0.034883
LOX	0.034823
GAPDH	0.034463
CD63	-0.034337
H19	-0.034172
FSTL1	-0.033920
ND2	-0.033534
NDUFC1	-0.033438
ATP5O	0.033426
MYL3	0.033276
NDUFV2	0.033246
TXNRD1	0.032975
COX8A	-0.032428
RAF1	-0.032356
DBP	-0.032200
PPP1CB	0.032149
FABP4	0.032110
RPS3	-0.032039
RPS12	-0.032035
LDB3	0.032029
KCNC4	-0.032028
GOT2	0.031964
GRINA	0.031816
CA3	0.031633
RHEB	0.031174
RAB10	-0.031128
SLC3A2	0.030894
ND1	0.030889
PTP4A1	0.030773
PSMD2	-0.030645
ACTC1	-0.030342
TIMP2	0.030165
DUSP1	-0.030079
TUBA4A	-0.030001
TFRC	-0.029807
LCN2	0.029634
CD74	-0.029450
RPS21	-0.029328
VEZF1	-0.029298
PPP2CA	0.029280
RPS29	0.029212
C1QB	0.029074
UBR5	0.029060
LDHA	0.028934
SERPINH1	-0.028791
RPLP2	-0.028785
JUN	-0.028740
ALDH1A1	0.028590
ANKRD1	0.028327
TOM1L2	0.027956
NDUFA5	-0.027888
TCEB1	-0.027791
PARK7	-0.027324
CPT1B	0.027265
NDUFA3	-0.027223
MYL4	-0.026866
RPS15A	-0.026809
PRKAR1A	-0.026677
POSTN	-0.026580
FXYD1	-0.026567
RPS25	-0.026171
HSPD1	-0.026040
RPL27A	-0.025946
UQCR11	0.025701
NDUFA9	-0.025573
HADHA	0.025192
MYOD1	0.025184
TIMM17A	-0.024875
PRNP	-0.024862
NEXN	-0.024851
ATP1B3	-0.024800
HADHB	0.024653
ATP5A1	0.024629
ECH1	0.024609
SLC2A4	0.024540
CITED2	-0.024186
PGM2	0.023805
ACY1	0.023788
NDUFB6	-0.023778
ATP5C1	0.023726
ATP1A2	0.023657
PPP1CA	-0.023573
EMP1	-0.023537
RPS23	-0.023524
UBE2G2	0.023492
CPD	0.023422
RPL12	-0.023414
CFB	0.023400
CNBP	0.023347
RPS15	-0.023289
YBX3	0.023215
RPL23	0.023210
RPL19	-0.023019
MAP2K6	-0.022977
KNG1	0.022932
PKIA	-0.022747
MYL1	0.022724
MRPL45	0.022721
HSP90AA1	0.022690
TNFRSF21	-0.022490
CAP2	-0.022375
RPL27	-0.022341
DYNLL1	-0.022211
ACADL	-0.022117
SOD1	-0.022082
GSTP1	-0.021788
TUFM	0.021776
GABARAP	0.021682
S100A8	0.021631
NDUFA6	-0.021382
RPL10	-0.021245
COL15A1	-0.021162
RPL9	-0.021109
SERBP1	-0.021074
RPS13	-0.021041
UCP3	0.021034
CALU	-0.021008
TCP11L2	-0.020934
ANXA5	-0.020906
COL1A2	0.020892
MLLT3	-0.020765
HK2	0.020760
GNB2L1	-0.020664
RPL31	0.020598
MYL9	-0.020534
RPL7A	-0.020449
GNG5	-0.020428
DHRS7C	-0.020188
SERPINE2	-0.020127
GNPAT	0.020120
IDH3G	0.020098
CYP27A1	0.020069
CLU	0.020062
PSMB5	-0.019882
NDUFB8	-0.019856
JUNB	0.019833
SERPING1	0.019719
GPX4	-0.019516
UBXN1	0.019484
TMOD1	0.019427
HSD11B1	-0.019408
EGR1	-0.019334
LAMC1	0.019314
SLC37A4	-0.019263
SOCS3	0.019258
LOXL1	-0.019166
CAPN3	-0.018895
ACADVL	0.018733
GRB10	0.018659
ARNTL	0.018573
COX1	0.018494
CS	0.018458
TUBB	-0.018391
ECE1	0.018376
FGA	0.018294
BTG2	-0.018265
EEF1A2	-0.018261
CD81	-0.018230
UQCRC2	-0.018182
PDLIM1	-0.018086
GINM1	0.018066
RPL6	-0.018060
PLEC	0.018036
ME1	-0.018016
HDLBP	0.017972
PMEPA1	-0.017913
MMP14	0.017847
NACA	0.017568
PVALB	0.017515
LITAF	0.017495
SNRPB	-0.017400
LGALS3	0.017347
DCAF6	0.017322
PPP2CB	0.017285
NPHP1	-0.017284
RHOB	0.017201
P4HA1	-0.017194
ATF3	-0.017088
ACSL6	-0.017046
GAA	0.017033
CAPZA2	-0.017014
STAT5B	-0.016989
BTG1	0.016908
PCOLCE	-0.016879
CTDSP1	-0.016831
PAIP1	-0.016760
GRPEL1	0.016737
TLE1	0.016646
COX7A2L	-0.016641
RPL18	-0.016607
GNAS	0.016299
EIF3B	0.016214
PGK1	0.016093
CXCL14	-0.016067
IGFBP6	0.016061
NOL3	0.016044
FGG	0.016041
AUH	0.016033
CCNG1	0.015916
CACNA2D1	-0.015726
KTI12	0.015706
ATP6V0C	0.015671
TIMM23	-0.015620
CLCN1	-0.015493
GSTM2	0.015487
CPA1	-0.015445
RPL28	-0.015331
CDKN1A	0.015298
IDH2	-0.015281
CISH	0.015235
SUCLG1	0.015134
PTPN3	-0.015036
RPL11	-0.015029
CAV3	-0.014893
IRF1	0.014789
GAS6	0.014712
NME2	0.014701
EGLN3	-0.014690
UBE2B	-0.014678
HNRNPAB	0.014677
AP2M1	-0.014666
C3	0.014515
ANAPC16	0.014511
GPD2	-0.014471
PMP22	0.014464
YWHAG	-0.014413
AES	0.014405
ATP6V1F	-0.014391
ZFP36	0.014373
NDUFS4	-0.014316
PPM1A	-0.014308
NDUFB5	-0.014306
SLC25A11	0.014297
GMPR	-0.014296
TXN2	0.014254
TOR1AIP1	0.014244
TSPO	0.014230
RPL36AL	-0.014149
CTSB	0.014064
CHRNB1	-0.014050
KLC1	0.014038
SOD2	-0.013942
RABAC1	0.013934
HSPA9	0.013840
ASPH	0.013808
RPL17	-0.013783
CANX	-0.013765
EIF5B	0.013763
RPLP0	0.013738
MFGE8	-0.013731
PSMC4	0.013720
MAP2K1	-0.013458
CYB5R1	-0.013447
COX5A	0.013417
NEB	0.013403
EIF3D	0.013373
OXR1	-0.013317
NRBP1	0.013315
NDUFS8	-0.013289
ADK	-0.013268
PCNA	-0.013261
COX6A1	-0.013223
YBX1	0.013113
RPS10	-0.013100
GSTM1	-0.013019
KCNJ11	-0.012865
MYADM	-0.012863
CREG1	0.012862
RPSA	-0.012821
MRFAP1	0.012691
PHB2	0.012631
GTF2A2	-0.012629
FMOD	0.012547
IVD	0.012512
BLMH	-0.012506
UBE2J2	0.012478
SPP1	0.012358
NCL	0.012301
PEBP1	-0.012221
NEK7	-0.012204
AKAP12	-0.012203
BSG	0.012138
EIF2S1	0.012126
COL3A1	-0.012096
RPL37	-0.012089
MCRS1	0.012088
ARF4	-0.012066
ERCC1	0.012056
GDA	0.012032
PTTG1IP	0.011991
EEF1G	-0.011971
OAT	0.011970
PGAM2	0.011955
ATP5D	-0.011894
PPIB	-0.011892
TMEM59	-0.011859
KANK2	0.011834
H2AFX	0.011807
CAV1	0.011806
FBP2	0.011769
FTL	0.011652
HNRNPC	0.011647
PECAM1	0.011607
S100A4	-0.011588
TARS	0.011581
AGTPBP1	0.011549
RBBP7	-0.011536
SH3KBP1	-0.011500
ND4	-0.011423
BECN1	-0.011419
TMED2	0.011314
VDAC1	-0.011262
PLA1A	0.011253
MAOA	0.011237
MDH1	0.011219
SCARB1	-0.011201
BGN	-0.011193
FOS	-0.011140
SREBF1	-0.011077
FKBP1A	-0.011029
SLC28A2	0.011028
PTOV1	0.011017
TUBB4B	-0.011009
ATP5G1	-0.010994
CLTC	-0.010993
AGO2	0.010984
RPS6KB1	-0.010974
ARHGAP10	0.010945
RPL13A	-0.010931
PGAM1	0.010896
IGF2R	-0.010872
RNASE4	0.010808
ARFGAP2	0.010736
BIN1	-0.010734
H2AFZ	-0.010728
ABCC9	-0.010722
HUWE1	0.010701
RPL15	0.010680
IGFBP5	-0.010679
SLC25A5	0.010660
SFRP4	-0.010637
SCN1B	-0.010627
DAPK2	-0.010555
FDFT1	-0.010549
VMP1	0.010542
PRKCDBP	0.010534
CBX1	-0.010525
LAMTOR1	-0.010468
SPARCL1	-0.010455
CYB5A	-0.010436
DARS	0.010434
ARF5	0.010398
MTDH	0.010394
PDHB	-0.010375
COLQ	-0.010354
SH2B2	-0.010346
TRIM63	-0.010336
CAPN2	0.010331
ITGB1	0.010305
PRDX3	0.010230
PROS1	-0.010221
GRN	0.010220
VEGFA	0.010196
PSMB4	0.010167
EEF2K	0.010162