!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estrogen
!ligand_id	CHEBI:50114
!cell_type	MCF-7 cells
!organism	human
!end_metadata
AGR3	0.081300
SGK3	0.077890
SGK1	0.075374
STC2	0.062548
NRIP1	0.061058
RASGRP1	0.059748
AMD1	0.058875
GALNT4	0.057515
PLOD2	0.056306
HCK	0.053430
AP5B1	-0.052488
PKIB	0.052054
C1orf226	0.051880
DDX21	0.051821
OTUD6B	0.050361
RERG	0.050249
WDR43	0.049601
CXCL12	0.046940
IGFBP4	0.046864
CEBPZ	0.046624
PGR	0.046584
KIF21A	0.045747
B3GALNT1	0.045637
PAK1IP1	0.043968
NPY1R	0.043180
CA2	0.043103
HIF1A	0.043033
PPIF	0.042988
TRMT10C	0.042033
PMAIP1	0.041755
HEY2	0.041668
NUP35	0.041325
CA12	0.041232
SIGLEC15	0.040640
NOC3L	0.040432
RHOBTB1	0.039740
MREG	0.039632
SLC38A2	0.039376
GREB1	0.038874
POC1B	0.038590
ABCE1	0.038437
RET	0.038162
TIPARP	0.037834
RAB31	0.037408
SIAH2	0.037226
NMD3	0.036953
TIFA	0.036859
USP31	0.036569
WDR3	0.036340
RAPGEFL1	0.036170
HCAR3	-0.035428
FOS	0.035243
UGCG	0.034529
HS3ST3A1	0.034472
KIAA0226L	0.034174
PUS7	0.034141
ZNF267	0.034003
PCDH8	-0.033996
RPF2	0.033991
RLN2	0.033813
SOX9	-0.033795
MYB	0.033779
AP1S1	0.033726
C10orf2	0.033697
LOC653602	-0.033685
ASNSD1	0.033506
ARHGEF26	0.033217
NOP58	0.033208
BLNK	-0.033009
ZNF146	0.032954
TMED8	0.032905
IFI6	-0.032786
SNAPC1	0.032338
TPD52L1	0.032314
PUS1	0.031982
FREM2	0.031773
FAM216A	0.031586
GRHL3	-0.031558
MYC	0.031269
GEMIN5	0.031051
RAMP3	0.031003
SLC22A5	0.030863
SMIM5	-0.030776
ELF1	0.030692
NOL11	0.030648
SYBU	0.030605
SUCO	0.030487
ORC3	0.030221
STC1	0.030155
RPS24	0.030055
C6orf211	0.030050
BRINP3	-0.029926
RNF43	-0.029668
TMA16	0.029320
DNAJB14	0.029291
ABHD2	0.029267
EGR3	0.029123
SLC26A2	0.029096
TFF1	0.028960
OXR1	0.028935
MAP4K3	0.028803
ZNF600	0.028751
BRIX1	0.028666
EIF1AX	0.028558
MBOAT1	0.028555
C10orf10	-0.028520
LONRF2	0.028481
SNHG15	0.028455
TSPYL5	0.028411
FAM46B	-0.028377
GPER1	-0.028342
SLC25A32	0.028323
LOC400099	-0.028312
ZBTB41	0.028308
RB1CC1	0.028239
NYNRIN	-0.028222
PTRH2	0.028197
SEMA3C	0.028192
PNPT1	0.028139
GNL3	0.028097
IFI27	-0.027964
THAP9-AS1	0.027838
AMMECR1	0.027471
ANKRD46	0.027463
ZBTB11	0.027390
ZNF239	0.027340
KIAA1033	0.027326
PSCA	-0.027305
HEXIM2	-0.027230
HSP90AA1	0.027219
RPP40	0.027218
MSH2	0.027162
DKC1	0.027135
C6orf141	0.027125
DKK1	0.027014
HOOK1	0.026983
NOL8	0.026933
BCAR3	-0.026707
USP35	0.026530
PSRC1	-0.026438
OLFML3	0.026329
BYSL	0.026311
FAM60A	0.026203
BST2	-0.026201
CIPC	0.026025
CBX3	0.025882
ASB13	0.025829
FBXO6	-0.025822
GNL2	0.025658
PIK3R1	0.025637
ZNF12	0.025617
OAS1	-0.025599
CTR9	0.025576
PHLDA1	0.025525
NUAK1	-0.025404
TBK1	0.025369
KCNK6	0.025307
SLC16A6	0.025267
NIP7	0.025248
CHD1	0.025142
ELOVL2	0.025100
B3GALT4	-0.025033
TCERG1	0.025028
KCNK5	0.024881
FABP5	0.024859
CISH	0.024855
FJX1	0.024817
UBL7-AS1	-0.024776
BMF	-0.024724
DDX18	0.024696
LRRC58	0.024674
HSPA13	0.024646
TMEM64	0.024623
BAK1	-0.024607
DFNB31	0.024484
SHOC2	0.024476
ZNF680	0.024327
CCT2	0.024196
CAND1	0.024112
SPOPL	0.024098
NIFK	0.024037
EMC2	0.023943
MAPK6	0.023923
E2F6	0.023903
NDUFAF4	0.023796
ARRDC4	0.023794
RANBP6	0.023773
TMEM45A	-0.023765
ICE1	0.023758
USP16	0.023754
IRF7	-0.023740
GNE	-0.023721
KLF4	0.023718
MTERF3	0.023661
TMEM140	-0.023651
LYAR	0.023589
PPRC1	0.023561
USP1	0.023486
EFNA1	-0.023474
SELL	-0.023438
HMMR	0.023411
SLK	0.023385
FFAR2	-0.023308
WDR75	0.023292
SRFBP1	0.023279
BTAF1	0.023263
DYNLT3	0.023249
TXLNG	0.023211
RBM24	0.023207
HILPDA	-0.023065
NEK7	0.023034
DEK	0.022999
C1orf106	-0.022962
PPAT	0.022962
RAB30	0.022908
RRS1	0.022893
LMBR1	0.022890
LRP8	0.022877
SLC9A3R1	0.022855
RND1	-0.022835
GSKIP	0.022829
HLTF	0.022828
NBPF1	0.022779
SLMO2	0.022757
EGLN3	-0.022669
ZNHIT6	0.022609
DBF4	0.022608
STAG2	0.022554
TAX1BP1	0.022547
EIF3J	0.022506
WDR36	0.022480
WDR12	0.022467
DLST	-0.022451
CHSY1	0.022417
SLC7A5	0.022367
MPHOSPH10	0.022364
NR4A2	0.022320
WWP1	0.022311
MAK16	0.022297
FYTTD1	0.022292
SSB	0.022265
CHAC2	0.022216
EPB41L4A-AS2	-0.022179
TAF1D	0.022109
EIF2S1	0.022093
CALCR	0.022074
ID1	-0.022051
ZNF516	0.022039
EDEM3	0.022023
NUDCD1	0.021994
SLC39A6	0.021992
ZNF423	-0.021981
PNPLA8	0.021977
PCDHB10	-0.021951
ZHX1	0.021913
POLR1B	0.021897
MIF-AS1	-0.021879
C12orf66	0.021799
EN2	0.021780
GTPBP4	0.021750
RECQL	0.021715
PALB2	0.021683
RANBP2	0.021662
ARFGEF1	0.021656
SMTNL2	0.021646
HMOX1	-0.021574
SELT	0.021532
BTG2	-0.021511
BDKRB2	-0.021466
KBTBD6	0.021466
RIOK1	0.021451
TOPBP1	0.021358
URB2	0.021357
EPN3	-0.021320
BAZ1A	0.021316
HAUS1	0.021280
GLA	0.021140
SOCS4	0.021139
BCL9L	-0.021137
ATP13A3	0.021098
DDX20	0.021075
PRPF38B	0.021024
TFRC	0.021012
MYBL1	0.020990
DTX4	-0.020979
PPM1K	0.020979
BZW1	0.020952
CHUK	0.020878
PPIP5K2	0.020872
FZD2	-0.020869
APOBEC3B	-0.020863
SP6	-0.020852
SLC39A10	0.020849
RRM2B	0.020818
PLAU	-0.020752
RPS6KB1	0.020726
FOXC1	0.020700
GIN1	0.020692
TSKU	0.020670
PRKRIR	0.020662
IL10RB	-0.020608
CNOT8	0.020520
ZNF14	0.020507
PRR15	-0.020496
GTF2IRD1	-0.020494
NOLC1	0.020463
CXorf24	-0.020442
COPS2	0.020438
NBN	0.020410
C2orf69	0.020399
SIDT1	-0.020395
ZNF354A	0.020386
ULK1	0.020362
DCUN1D4	0.020322
XPOT	0.020322
TMPO-AS1	-0.020268
VPS37A	0.020239
ZFYVE19	-0.020238
LINC01137	-0.020230
C2orf54	-0.020220
CTPS1	0.020207
COA7	0.020186
NEMF	0.020155
TAF9	0.020153
PRRT2	-0.020148
TIGD1	0.020117
NOP2	0.020076
SRSF7	0.020071
TMEM79	-0.020039
CRYZ	0.020016
CSE1L	0.020016
EP300-AS1	-0.019985
SUCLA2	0.019951
IFITM1	-0.019932
EPHB3	-0.019925
C6orf120	0.019921
KLF5	-0.019918
PSMB9	-0.019909
UAP1L1	-0.019901
SLC37A3	0.019894
POT1	0.019853
CCNH	0.019836
TPBG	0.019823
TOB1-AS1	-0.019805
MRPL1	0.019805
POLR1C	0.019803
TUBB2A	-0.019799
CMPK2	-0.019791
SELM	-0.019788
FAM198B	0.019773
CENPK	0.019754
ZUFSP	0.019748
PRPF4B	0.019720
SLC31A2	-0.019712
LOC643072	-0.019712
FASTKD3	0.019678
TMEM164	0.019672
FEM1C	0.019670
GRB7	-0.019638
RARA	0.019634
MKNK2	-0.019605
PLS1	0.019597
TIAM1	0.019592
KCNJ8	-0.019568
EXOC5	0.019567
MISP	-0.019557
NXT2	0.019550
XBP1	0.019548
GNA13	0.019519
CSRNP1	-0.019501
FRMD6-AS1	-0.019473
GATA6	-0.019470
GLCE	-0.019462
WLS	-0.019455
MSMB	0.019433
ABCB10	0.019414
LYPD3	-0.019405
CCDC86	0.019377
IFI35	-0.019353
C15orf37	-0.019349
ANKRD36B	0.019335
RASA4	-0.019316
ZC3H8	0.019301
RCL1	0.019285
RHPN2	0.019204
AKAP1	0.019200
KPNA3	0.019199
NEURL1B	-0.019163
CMTR2	0.019163
LRRC10B	-0.019146
PDCD2L	0.019135
SCYL2	0.019132
AHCTF1	0.019109
HNRNPU-AS1	0.019103
SHISA2	-0.019078
TOP2B	0.019064
FZD6	0.019058
FAM35A	0.019016
PRSS23	0.019007
ST8SIA4	-0.018989
PRPF40A	0.018983
CBWD1	0.018973
GTF2E1	0.018957
TTC37	0.018949
ATF1	0.018937
SLC19A2	0.018936
METTL8	0.018924
QSER1	0.018905
TOPORS	0.018900
NKRF	0.018871
LOC642361	-0.018870
MICB	0.018851
DHX36	0.018849
ATR	0.018827
HSPA4L	0.018785
ZNF823	0.018727
PTPLB	0.018692
NXN	-0.018692
SNX4	0.018687
HK2	0.018683
MAP4K5	0.018676
DNAJC2	0.018670
GEMIN4	0.018655
NFXL1	0.018646
VPS9D1	-0.018642
GPR133	-0.018632
SAT2	-0.018631
ZWILCH	0.018604
NUPR1	-0.018586
ZNF644	0.018579
ADO	0.018550
PPP4R2	0.018540
KCNN4	-0.018522
DHX33	0.018509
ABCD3	0.018464
LOC101927746	0.018442
PPAN	0.018413
UTP3	0.018409
TROVE2	0.018401
MORF4L2	0.018393
RIPPLY3	-0.018360
EIF4A2	0.018349
TOX2	-0.018337
SYNDIG1	0.018317
SACM1L	0.018314
SSTR5-AS1	-0.018272
LOC100190986	0.018258
DDIT4	-0.018248
GPRC5C	-0.018183
KISS1R	-0.018159
CLDN9	-0.018152
EXOSC9	0.018149
KLK11	0.018124
GMFB	0.018085
CCDC88C	0.018083
DMXL1	0.018083
INAFM2	0.018079
LOC100129129	-0.018074
MPND	-0.018057
SNX10	0.018043
POLR3F	0.018043
TTC3	0.018021
ZCCHC7	0.018021
IPO7	0.018017
C15orf48	-0.018006
THAP1	0.018001
TSEN2	0.017981
S1PR3	-0.017957
SCOC	0.017956
ZBTB21	0.017944
OSCP1	-0.017941
FAM83A	-0.017918
TMEM121	-0.017906
HIST2H2AA3	-0.017885
ENKD1	-0.017867
ZNF367	0.017849
NKX2-3	-0.017840
NAA50	0.017839
ZC3H15	0.017798
CYSRT1	-0.017780
HSPH1	0.017736
NBPF10	0.017729
AIMP1	0.017714
C5orf30	0.017713
UCK2	0.017706
DDX47	0.017680
RBM25	0.017671
SPAG4	-0.017664
ZNRF3	0.017663
SLC38A1	0.017637
SF3B1	0.017630
PIK3C2B	-0.017618
DLL1	-0.017610
ARID3A	-0.017609
SUOX	-0.017606
SLC6A14	0.017604
CIRH1A	0.017602
SLC20A1	0.017598
SFXN2	0.017588
SLC2A1	0.017583