!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Tretinoin
!smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
!drugbank_id	DB00755
!pubchem_cid	444795
!cell_type	NA
!organism	human
!end_metadata
TGM2	0.074523
CYTL1	-0.067045
BPI	0.063286
VIM	-0.061358
CCL24	0.060086
ALOX5AP	0.058033
SELL	0.053527
FGR	0.051276
MMP9	-0.049741
DHRS3	0.046177
PADI2	0.045948
SNORD41	-0.045222
EBF3	-0.043397
PSMB9	0.043171
FBP1	0.042958
LHFP	-0.042780
GNG2	0.042297
PRG2	-0.042182
HDC	-0.042128
PRAM1	0.041348
PSMB8	0.040729
SLC2A5	0.039648
CYP1B1	-0.039505
LYZ	-0.039326
C1orf186	-0.038797
IFITM10	0.037925
MS4A3	-0.037555
GPR97	0.037498
E2F5	-0.037380
ITGB7	0.037327
CDC42EP3	-0.036853
CD52	0.036724
RCSD1	0.036506
IRF1	0.036246
RNF125	-0.035782
S100A8	0.035408
PEA15	-0.035390
ECRP	-0.035249
PLCB2	0.035059
MIR142	-0.034877
SNORA71D	-0.034546
SERPINB1	0.034314
PADI4	0.034164
DEFA4	0.033974
AMICA1	0.033803
TNF	-0.033665
HK3	0.033593
ZEB2	-0.033442
KCNH4	0.033319
NQO1	-0.033278
TMEM173	0.032981
SMOX	0.032467
OCR1	-0.032339
SNORD14E	-0.032307
LRG1	0.032118
PARP14	0.032028
ARAP1	0.031988
FAM20C	0.031874
SNORA38B	-0.031811
MAP7D3	-0.031788
MCEMP1	0.031741
PKN1	0.031699
CXCR2	0.031587
CTSG	-0.031579
TAS2R4	-0.031528
RAB27B	-0.031396
ASS1	-0.031381
CA2	-0.031221
AHNAK	-0.031203
FCGR2A	-0.031042
SNORD13	-0.030868
SACS	-0.030818
SLC44A1	0.030812
NCF2	0.030791
VTRNA1-1	-0.030595
CA8	-0.030585
GPR84	-0.030574
GCA	0.030217
C12orf75	-0.029933
TNFAIP2	0.029877
CES1	0.029863
CHAC2	-0.029852
ERAP2	0.029655
FAM101B	-0.029637
FFAR2	0.029604
NCS1	-0.029592
TAF4B	-0.029536
CTSH	-0.029411
AFF2	-0.029261
CST7	-0.029220
CEP170P1	-0.029204
FLJ36840	-0.029175
RSU1	-0.029068
C1RL	0.029054
SLA	0.029015
NAF1	-0.028939
NLRC4	0.028799
SNORD14C	-0.028798
RNF130	-0.028756
HOMER1	-0.028620
LGALS1	-0.028611
TAS2R50	-0.028394
PCGF6	-0.028370
CHST11	-0.028352
CRTC3	-0.028342
ATP5G1	-0.028166
CD38	0.028154
CD44	-0.028037
IFI35	0.028031
CXCL10	-0.027952
CLEC5A	-0.027862
BCL2	-0.027824
RNU5D-1	0.027771
CHIC2	-0.027699
PAPD5	-0.027659
IL17RA	-0.027625
ITGAM	0.027612
OAS3	0.027505
CSF3R	0.027466
EBAG9	-0.027311
TNFAIP3	-0.027305
MT1F	-0.027128
BCL11A	-0.027102
LGALS3BP	0.027063
EMR2	-0.027019
ADA	0.026907
NARS2	-0.026894
PVRL1	0.026860
ZNF566	-0.026796
OGFR	0.026689
STK17B	-0.026637
ERRFI1	-0.026636
CYP4F3	0.026615
NAT8L	0.026608
SDC2	-0.026585
C10orf54	0.026463
GINS2	-0.026371
GM2A	0.026366
MORN2	-0.026225
DUSP10	-0.026220
ZNF718	-0.026182
CRISP3	0.026152
ZNF138	-0.026147
ASRGL1	0.026139
CAMKK1	0.025996
RARRES3	0.025899
SNORA24	-0.025862
FAM46C	-0.025783
ITGAX	0.025742
RNU4ATAC	-0.025735
GNG4	-0.025666
ITGA6	0.025564
ALAS1	0.025513
ASB2	0.025510
LFNG	0.025479
GBP5	0.025303
MRC2	-0.025292
DDX60L	0.025269
CFP	0.025265
DCP1A	-0.025194
CTSS	0.025075
TRAM2	-0.024991
ZRANB3	-0.024897
LRRC8B	-0.024842
CTSW	-0.024821
PTPRE	-0.024788
TMTC2	-0.024767
ICAM1	0.024763
COTL1	0.024754
PDE3B	-0.024750
CCNE2	-0.024741
SEMA6B	0.024738
RNU5A-1	-0.024685
USP17L6P	0.024662
MRPL13	-0.024610
PDCD4	0.024525
CDK5RAP3	0.024513
DAAM2	0.024412
ELOVL3	-0.024402
PSMB10	0.024372
MGST2	0.024323
MMP2	-0.024309
HLA-C	0.024296
GSAP	-0.024263
HLA-B	0.024261
RGS1	0.024255
MERTK	0.024251
GPR160	0.024219
DTD2	-0.024150
C15orf61	-0.024119
NCALD	-0.024092
AAED1	-0.024083
LOC100134822	-0.024068
TAS2R14	-0.024027
MT2A	-0.023954
DCUN1D4	-0.023951
MRPS11	-0.023873
DTWD2	-0.023836
HIP1	-0.023833
MINOS1	0.023732
UBA7	0.023721
ATMIN	-0.023682
PALLD	0.023652
SNORD59B	0.023641
PTPLB	-0.023626
FAM210A	-0.023617
SLC20A1	-0.023615
SNORA23	-0.023579
PARP9	0.023488
PRDX5	0.023446
KIAA1147	-0.023434
EMP3	-0.023418
RPP40	-0.023415
SLC7A2	-0.023368
NAGA	0.023350
SLC39A14	-0.023347
COX16	-0.023315
RPP38	-0.023299
CTSD	0.023294
SLC31A1	-0.023290
DDIAS	-0.023261
SLC7A11	-0.023250
INPP5A	-0.023249
UBXN8	-0.023238
RPPH1	0.023234
SNORA45A	-0.023181
HIST1H4D	-0.023033
SERPINB8	-0.023000
TBL1X	-0.022998
CD300A	0.022991
ASGR2	-0.022989
DCAF17	-0.022984
PIK3C2A	-0.022861
FYN	-0.022832
ARHGAP12	0.022798
PSMB6	-0.022718
FAM43A	-0.022714
ZNF578	0.022708
MOK	-0.022685
STAMBPL1	-0.022682
TGIF1	-0.022681
CASP7	0.022623
MIR181B1	-0.022600
PEAK1	-0.022591
GUSB	0.022578
RARB	0.022567
CMSS1	-0.022518
MRPL40	-0.022461
SNORA21	0.022439
ICAM4	0.022421
LGALS9	0.022411
ROR2	0.022407
ARSK	-0.022378
CAPN2	-0.022316
FCHSD2	-0.022312
DAPP1	0.022286
ALMS1	-0.022255
GEMIN5	-0.022212
SREBF1	0.022210
MYO9A	-0.022198
NT5DC2	-0.022198
PSD3	-0.022193
HLA-A	0.022179
TAS2R19	-0.022179
ROPN1L	-0.022146
CD101	0.022138
POP4	-0.022126
CTNNAL1	-0.022115
TULP4	-0.022110
PHACTR4	-0.022092
FAM118B	-0.022076
HCLS1	0.022051
CD58	-0.021997
CCR1	0.021954
RAB38	-0.021896
ANXA2	-0.021835
ANKRD12	-0.021834
P2RY13	0.021791
CCDC88B	0.021782
HLA-G	0.021736
TMEM254	-0.021730
P2RY2	-0.021715
BNIP3L	-0.021708
LAMB3	0.021673
TAF9B	-0.021661
SLC10A5	-0.021654
MARC1	-0.021633
METTL9	-0.021605
PPP2CB	-0.021605
DUSP6	0.021602
ST3GAL6	-0.021569
MYO1B	-0.021549
RDH10	-0.021514
NT5DC3	-0.021494
ITPR2	0.021483
HEXB	-0.021478
HVCN1	-0.021443
RYBP	-0.021431
SLC7A5	-0.021421
ZNF675	-0.021413
SLC1A4	-0.021406
NETO2	-0.021372
RBBP9	-0.021357
AGO1	0.021347
HAUS1	-0.021318
ZDBF2	-0.021289
CDC34	-0.021289
TXNL1	-0.021278
SASS6	-0.021277
TULP3	-0.021257
ADI1	-0.021257
SGOL1	-0.021208
FKBP2	0.021205
HS6ST1	-0.021126
ZNF429	-0.021126
WT1	-0.021088
LRRC37B	-0.021084
THBS1	-0.021077
NPM3	-0.021034
UFSP2	-0.020986
PLEK	0.020868
ABHD2	0.020857
GTPBP10	-0.020830
MDK	0.020819
MAML2	-0.020817
ZNF480	-0.020791
SSBP2	-0.020784
HEBP1	-0.020772
MNAT1	-0.020761
FNTB	-0.020737
PSMD10	-0.020731
GTF2A2	-0.020724
MIR186	-0.020710
HCG8	-0.020688
SNORD4B	-0.020686
EPAS1	0.020681
CPSF4L	0.020679
PARGP1	-0.020673
CEBPE	0.020670
RASAL2	-0.020667
USP13	-0.020561
OSBPL11	-0.020552
H3F3C	-0.020550
NUFIP1	-0.020508
CCDC59	-0.020491
PSMG2	-0.020479
DIAPH2	-0.020455
SNORD115-21	0.020449
SDS	0.020417
TNFSF10	-0.020417
LINC00266-1	-0.020395
FSCN1	-0.020386
FBN2	-0.020372
SAMD9L	0.020345
TNIK	-0.020326
MT1X	-0.020322
DRAM1	0.020321
RPAP2	-0.020287
HYLS1	-0.020280
UBR3	-0.020263
WSB2	0.020261
TMEM160	-0.020240
SNORD115-3	0.020214
DNAAF2	-0.020194
PAK1	0.020192
DOCK10	-0.020184
IKZF5	-0.020147
ASIC1	-0.020146
ATXN7L1	-0.020144
CSPP1	-0.020116
MYO1F	0.020113
GNA11	-0.020074
ZBTB16	-0.020066
TMC8	0.020064
JMY	-0.020062
TPTE2P3	-0.020061
NOL7	-0.020047
APOL1	0.020038
STRADB	-0.020035
NUDT7	-0.020035
LSM12	-0.020032
KIAA2026	-0.020008
APBB1IP	0.019988
CCDC112	-0.019987
ZNF841	0.019965
PTGER4	-0.019952
NCOA3	0.019950
LRRC8C	-0.019943
SNAPC3	-0.019941
ZEB1	-0.019914
TMEM261	-0.019911
IRX3	-0.019907
MIR32	-0.019896
ATP1B1	-0.019880
ZNF706	-0.019863
F3	-0.019855
CBLL1	-0.019837
NEDD4L	-0.019835
PCMT1	-0.019822
POLE2	-0.019815
KCNQ5	-0.019812
FAM117B	-0.019795
CLOCK	-0.019791
ATP2A1	0.019781
EMR3	0.019757
PACRGL	-0.019740
PSG8	0.019735
SNORD45A	-0.019733
CCL5	-0.019732
GIN1	-0.019725
LIPN	0.019703
CDC42EP4	0.019700
METTL7A	0.019696
MRPL50	-0.019694
EPX	-0.019689
SELP	0.019660
CYP2R1	-0.019624
SNORA76A	-0.019605
USP3	-0.019604
NDUFA13	0.019579
MCAM	-0.019571
SYT11	-0.019570
SPRY4	-0.019568
SNORD4A	-0.019568
TCF12	-0.019537
ZNF385A	0.019521
MGST1	-0.019506
LOC100131581	-0.019500
CHRNA5	-0.019466
HEBP2	-0.019450
GTF2H1	-0.019427
TAS2R31	-0.019422
CNOT4	-0.019422
PLD4	0.019377
ABI2	-0.019333
TMEM156	0.019324
ACBD4	0.019319
SLC8B1	0.019291
OXNAD1	-0.019284
MALAT1	0.019282
SNORD115-48	0.019280
SNORA13	-0.019280
MRPL35	-0.019237
C15orf41	-0.019228
QSER1	-0.019223
STX2	-0.019222
CYBA	0.019205
NFE2L3	-0.019195
GLIPR2	-0.019178
PDP2	-0.019153
IQGAP2	-0.019141
POLR3G	-0.019134
VAV2	-0.019119
MTA3	-0.019115
BTN3A3	0.019094
UGCG	-0.019082
ADD3	0.019080
THEMIS2	0.019071
TRMT61B	-0.019067
COQ3	-0.019043
TMEM184C	-0.019023
UNC5C	-0.019015
HIST1H2BK	-0.019012
HMGA2	-0.018999
SPNS2	-0.018985
STS	-0.018975
ANPEP	-0.018963
REEP5	-0.018960
CCNT1	-0.018944
TMC6	0.018941
ZFAND2A	-0.018919
TXNL4A	-0.018910
FAIM	-0.018905
PTGS1	0.018885
PLXND1	-0.018846
MINA	-0.018842
MLC1	-0.018841
DDHD1	-0.018840
TMEM147	-0.018835
SCARNA9L	-0.018831
CCR3	0.018825
NIT1	0.018818
BRI3	0.018802
IFT57	-0.018793
TFEC	0.018785
IFI6	0.018784
CD300LB	0.018765
TMEM87B	0.018762
IFT74	-0.018759
LMLN	-0.018755
GNA15	-0.018726
ZBTB11	-0.018720
COX5B	-0.018685
IFNGR1	0.018678
CGRRF1	-0.018672
PIK3CG	0.018668
TMED10P1	-0.018667
CCDC34	-0.018666
IRAK3	-0.018648
HSP90AA6P	-0.018645