!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	estrogen
!ligand_id	CHEBI:50114
!cell_type	alpha null aorta
!organism	mouse
!end_metadata
FOSB	0.100376
FOS	0.085456
CYR61	0.082561
CISH	-0.061551
ACSM3	-0.055455
CLSTN3	-0.054919
RASD1	-0.054695
MYL7	-0.052393
ZFP36	0.051979
SGK2	-0.047697
IMMP2L	-0.046719
PPP1R1A	-0.046636
MRS2	-0.046489
JUNB	0.046398
TMEM79	-0.045392
TTC25	-0.045068
ADTRP	-0.045014
PON1	-0.044692
NR4A1	0.044635
CEBPA	-0.044084
PROCA1	-0.043857
PEX11A	-0.043648
DSE	0.043553
ASPG	-0.042840
NUBPL	-0.042687
LIPT2	-0.042262
CLYBL	-0.042187
PTGS2	0.042173
CXCL2	0.042042
EGR2	0.042003
ABCB8	-0.041690
BTG2	0.041658
SLC2A4	-0.041421
TUBA8	-0.041326
PPP1R15A	0.040841
PFKFB1	-0.040736
CFD	-0.040504
ELOVL3	-0.040475
ACACA	-0.040092
SOCS3	0.040006
AQP7	-0.039898
CMBL	-0.039841
MME	-0.039742
RETN	-0.039351
ALKBH7	-0.039183
LRG1	-0.039148
SLC25A34	-0.038816
TST	-0.038748
STAT5A	-0.038638
PLBD1	-0.038593
AGPAT2	-0.038568
EGR1	0.038160
GMPR	-0.037972
PSMB9	-0.037829
FOXRED1	-0.037691
C11orf54	-0.037539
SLC27A2	-0.037147
GYS2	-0.036849
FUOM	-0.036793
ZNF317	0.036672
ATF3	0.036624
CYP2F1	-0.036566
GSTZ1	-0.036502
PLIN5	-0.036496
DUSP1	0.036488
ACSF3	-0.036409
IER2	0.036080
ELOVL6	-0.036056
DNAJC15	-0.035691
FAM195A	-0.035682
NEGR1	-0.035674
MRPS27	-0.035649
FXN	-0.035543
COX7A1	-0.035535
PET100	-0.035420
UCP3	-0.035336
CHCHD10	-0.034946
LDHD	-0.034890
MMACHC	-0.034768
SLC36A2	-0.034726
NAT8L	-0.034661
LPAR6	-0.034619
FLAD1	-0.034587
PDHX	-0.034549
AKAP1	-0.034443
SLC22A3	-0.034382
AIFM2	-0.034304
UQCR10	-0.034195
KLB	-0.034192
TMEM182	-0.034191
AMY2A	-0.034093
SCARB1	-0.034016
EMC9	-0.033935
GSTO2	-0.033829
PDHB	-0.033805
PVRL2	-0.033800
LACTB2	-0.033676
MEX3C	0.033672
CDH2	-0.033659
ADCK4	-0.033655
EBF2	-0.033652
OPLAH	-0.033394
GMNN	-0.033390
LACE1	-0.033345
ASNS	-0.033324
ZSWIM7	-0.033272
ASPA	-0.033099
SLC22A23	-0.032997
C7orf55	-0.032984
KLHL29	0.032976
TDRP	-0.032870
ISCA2	-0.032850
NEIL1	-0.032767
CD274	-0.032725
BCL2L13	-0.032510
ACADS	-0.032348
CD1D	-0.032320
TMEM45B	-0.032164
DECR1	-0.032061
SBK1	-0.032026
KANK4	0.032019
KIAA1598	-0.031978
PHLDA3	-0.031918
PLIN2	-0.031701
C1QTNF9B	-0.031686
ALAD	-0.031686
ECHDC3	-0.031635
TOMM40	-0.031540
CIDEC	-0.031512
PM20D1	-0.031466
ACAA2	-0.031457
TF	-0.031371
PEX5	-0.031300
PDK2	-0.031252
CISD3	-0.031233
GPX3	-0.031225
AGMO	-0.031176
CYP2E1	-0.031051
NRG4	-0.031004
PPARA	-0.030888
ECHS1	-0.030859
LGALS12	-0.030806
ME3	-0.030711
PAOX	-0.030695
P4HA2	0.030572
GOT1	-0.030499
MAP3K8	0.030468
HEG1	-0.030440
KCNK3	-0.030354
HSPH1	0.030300
MECR	-0.030286
NFKBIZ	0.030253
HLX	-0.030235
PAQR9	-0.030219
TBC1D32	-0.030108
SLC27A1	-0.030053
ELTD1	-0.030011
TMEM120B	-0.029975
ATPAF2	-0.029916
CTGF	0.029877
PPIL4	0.029865
ECH1	-0.029838
CIDEA	-0.029821
GPAM	-0.029813
HSD17B12	-0.029777
PYGL	-0.029678
PC	-0.029600
FAM69B	-0.029591
DLAT	-0.029591
FBP2	-0.029462
PGD	-0.029448
ADAMTS1	0.029322
DGAT2	-0.029281
PPIF	-0.029252
MRPS2	-0.029250
EPHX2	-0.029226
ADIPOQ	-0.029226
ACAT2	-0.029161
DTNBP1	-0.029155
DCAF4	-0.029114
MRPS36	-0.029093
PLA2G12A	-0.029017
IL15RA	-0.029009
JUN	0.028990
HADHA	-0.028948
MCCC2	-0.028936
DDT	-0.028893
RETSAT	-0.028830
EBF3	-0.028805
PXMP4	-0.028743
ECHDC1	-0.028704
MTX2	-0.028643
NDUFS3	-0.028590
GNPAT	-0.028588
LGALS4	-0.028556
ADIPOR2	-0.028552
ACOT13	-0.028552
PTPLB	-0.028476
GADD45G	0.028473
MRPS35	-0.028393
CPN2	-0.028391
PNPLA3	-0.028319
CLIC5	-0.028291
NR1H3	-0.028234
CA3	-0.028150
HOXA7	-0.028093
NABP1	-0.028063
ENTPD4	-0.028058
DBT	-0.028023
CAAP1	0.028008
MLXIPL	-0.028000
KCTD15	-0.027989
SDHB	-0.027951
SMIM8	-0.027923
MPZL2	-0.027909
KLF4	0.027870
PHYH	-0.027825
GEM	0.027816
CRLS1	-0.027731
FBXO21	-0.027707
CA4	-0.027705
ETFB	-0.027694
CYC1	-0.027626
NDUFS6	-0.027567
C7orf43	0.027567
COX19	-0.027547
PPARG	-0.027541
SFT2D3	-0.027479
BCL3	-0.027453
PPCS	-0.027446
PTPMT1	-0.027398
MSRB2	-0.027379
PIM1	-0.027373
TMEM14C	-0.027350
GYS1	-0.027265
UCK1	-0.027250
OTOP1	-0.027250
CDS1	-0.027213
PCCB	-0.027167
ECSIT	-0.027163
GBE1	-0.027156
HIBCH	-0.027127
SLC25A20	-0.027080
TEFM	-0.026994
RNF152	-0.026927
PLA2G16	-0.026927
TPPP	-0.026895
KIAA1919	-0.026881
DNAJB1	0.026832
SLMO2	-0.026832
UQCR11	-0.026786
ACADVL	-0.026773
BIVM	-0.026625
BLVRB	-0.026535
POLDIP2	-0.026511
DSP	0.026495
DHCR7	-0.026447
UQCRFS1	-0.026389
MCEE	-0.026362
SLC25A33	-0.026320
C8orf4	-0.026297
AK2	-0.026262
NDUFS1	-0.026174
COQ5	-0.026156
PYURF	-0.026149
APLN	-0.026147
MYL1	-0.026130
FAM73B	-0.026060
TIMM10	-0.026040
SDHAF1	-0.025990
CCS	-0.025983
MPC1	-0.025962
HIST1H3C	-0.025938
ATP5O	-0.025874
PDHA1	-0.025859
C11orf71	-0.025816
ABHD11	-0.025803
SLC25A11	-0.025741
PEX7	-0.025716
LIPT1	-0.025662
ME1	-0.025618
NDUFA8	-0.025615
UQCRC1	-0.025604
FH	-0.025581
CHDH	-0.025572
AGPAT3	-0.025539
STAU2	-0.025503
KBTBD7	0.025463
GIMAP4	-0.025461
ACSL5	-0.025348
TMEM37	-0.025328
COQ7	-0.025318
TSPAN18	-0.025310
PEX3	-0.025305
CHKB	-0.025228
GADD45B	0.025225
TAMM41	-0.025222
MRPL39	-0.025197
CCBL2	-0.025184
TMEM120A	-0.025113
CBR4	-0.025101
SMUG1	-0.025048
PCYT2	-0.025031
GPRC5B	-0.025019
RUVBL2	-0.025019
NDUFV1	-0.025000
SIK2	-0.024983
S100A1	-0.024980
MTFP1	-0.024969
EIF4E3	-0.024965
TMEM53	-0.024962
CCRN4L	-0.024921
EMC6	-0.024900
FAHD1	-0.024858
PRKAR2B	-0.024853
FAM210A	-0.024848
DECR2	-0.024843
IMMT	-0.024829
APLNR	-0.024800
PPP6R1	-0.024790
CLUH	-0.024781
SUOX	-0.024757
DARS2	-0.024727
ACADL	-0.024727
PPP1R3B	-0.024704
MRPS33	-0.024697
TIMM23	-0.024668
C20orf27	-0.024646
OCEL1	-0.024620
TMEM192	-0.024600
CLEC1B	-0.024570
COA5	-0.024533
ADRBK2	-0.024502
GPC3	0.024498
THOC6	-0.024460
ATP5D	-0.024458
SGK1	0.024440
GRPEL1	-0.024436
NDUFC1	-0.024427
PRDX3	-0.024399
NPY	-0.024390
NIPSNAP1	-0.024384
ORMDL3	-0.024369
IMPA2	-0.024365
ETFA	-0.024349
NUDT7	-0.024346
TMEM88	-0.024344
LGALS3BP	-0.024336
MRPS16	-0.024278
COQ6	-0.024263
APOO	-0.024244
FFAR4	-0.024222
ATP8B1	0.024216
RGCC	-0.024126
SLC40A1	-0.024115
PLA2G7	-0.024102
DNAJC28	-0.023985
STAB1	-0.023956
FABP4	-0.023946
ZDHHC23	0.023940
NIT2	-0.023922
FDX1	-0.023919
SUCLG1	-0.023912
SLC25A35	-0.023905
ATP2B4	-0.023862
NDUFB5	-0.023836
CARHSP1	-0.023825
C19orf80	-0.023823
LDHB	-0.023822
DYNLL2	-0.023780
RGL3	-0.023763
DCTPP1	-0.023746
CITED2	0.023710
UBIAD1	-0.023706
PIK3R3	-0.023680
GYPC	-0.023665
EMB	0.023634
ENDOG	-0.023626
C6orf57	-0.023623
FKBPL	-0.023606
GPD2	-0.023584
CRAT	-0.023583
DUSP10	-0.023538
LPIN1	-0.023459
NDUFS8	-0.023446
ISOC1	-0.023442
BASP1	-0.023441
MRPL22	-0.023430
CCDC122	-0.023430
TFE3	-0.023402
CSRNP1	0.023399
MRPL46	-0.023396
AACS	-0.023378
ATP5S	-0.023356
MRPS34	-0.023338
CD36	-0.023329
MRPL44	-0.023329
SERPINE1	0.023288
ADCK3	-0.023250
ADSSL1	-0.023233
AGFG2	-0.023223
NDUFA10	-0.023178
RXRG	-0.023147
NDUFAF1	-0.023127
ERRFI1	0.023123
SLC4A4	-0.023115
SPSB3	-0.023109
IDH3G	-0.023106
KCNK6	-0.023103
SUV420H2	-0.023102
ACAD11	-0.023099
HIGD2A	-0.023067
UCP1	-0.023059
NDUFS7	-0.023054
HK2	-0.023022
MRPL43	-0.022980
MRPL16	-0.022959
SGPL1	-0.022951
MALSU1	-0.022951
NDUFA4	-0.022950
HP	-0.022936
GHITM	-0.022931
BCKDHA	-0.022924
CYB5B	-0.022920
TRAPPC1	-0.022885
MLYCD	-0.022872
TP53I11	-0.022869
ACO2	-0.022856
METTL20	-0.022842
DGAT1	-0.022837
BSCL2	-0.022781
TOMM40L	-0.022775
L3HYPDH	-0.022726
SLC37A4	-0.022698
KCTD1	-0.022649
NDUFA7	-0.022619
TSPAN12	-0.022618
CS	-0.022615
SIRT3	-0.022602
GCSH	-0.022591
CSAD	-0.022569
EHHADH	-0.022560
PDK1	-0.022510
G6PD	-0.022462
VEGFB	-0.022427
LDHA	-0.022411
MRPL32	-0.022358
AHCYL1	-0.022348
NDUFA9	-0.022337
IDH1	-0.022334
PSPH	-0.022332
MRRF	-0.022319
FAM63B	-0.022315
RAB1B	-0.022314
CES1	-0.022309
LPL	-0.022277
ADHFE1	-0.022211
PPA1	-0.022198
IDH3A	-0.022196
SIRT4	-0.022190
HYAL2	-0.022155
PIEZO1	-0.022137
TIMM13	-0.022121
LIPE	-0.022119
DPYD	-0.022109
HINT2	-0.022102
KDR	-0.022097
ABHD14B	-0.022053
NUDT19	-0.022031
TIMM44	-0.021989
PPDPF	-0.021976
ADCY3	-0.021939
GTF3C3	-0.021935
UQCRC2	-0.021919
CDC34	-0.021918
MRPL40	-0.021917
SDHD	-0.021911
USMG5	-0.021909
WDR24	-0.021893
MPEG1	-0.021852
PGLS	-0.021852
BCKDHB	-0.021847
MPDU1	-0.021833
NDUFV2	-0.021811
CHSY3	0.021767
FITM2	-0.021760
MCCC1	-0.021755
GP9	-0.021746
HSPA8	0.021733
HSPB1	0.021733
PSMA3	-0.021708
NDUFAB1	-0.021703
ALDH4A1	-0.021683
CD163	0.021662
TBRG4	-0.021660
DNAJB4	0.021631
SLC25A51	-0.021623
ADRB3	-0.021609
C6orf136	-0.021608
PCK1	-0.021607