!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!ligand_name	Interleukin 1β
!ligand_id	3553
!cell_type	insulinoma cell line (Pdx1 overexpression)
!organism	rat
!end_metadata
CXCL2	0.543479
NFKBIA	0.284315
CXCL3	0.261595
NFKB2	0.194378
SEMA4A	0.182279
SOD2	0.151010
PDZK1IP1	0.122643
IRF1	0.105071
ALCAM	0.097993
IAPP	0.093789
RIPK2	0.075889
SLC37A1	0.075806
ALDOB	-0.075729
NFKB1	0.069380
STAP2	0.068376
RRAS2	0.068302
SDC4	0.064081
RELT	0.063647
EXOC6	0.062502
F11R	0.061988
BTG1	0.061874
MAPKAPK2	0.060096
MSMO1	-0.057543
LRRC42	0.057380
MICALL2	0.055326
NFKBIZ	0.054252
TMEM206	0.053922
RAPGEF5	0.053155
EZR	0.052239
SYNJ1	0.051363
SLC25A4	0.050250
CXCL10	0.050108
UBD	0.049983
BIRC3	0.049500
PIM2	0.048536
SWI5	-0.047711
SPINT1	0.047523
ARG1	0.047150
DYNLL1	-0.046159
HMGB2	-0.046157
GADD45A	0.045148
AP1S2	-0.044531
ODC1	0.044518
STX7	0.044472
DZIP1L	0.043722
PSMA6	0.043545
UBA2	0.043380
LTB	0.043190
TACC2	0.042341
ZC3H12A	0.041888
MVP	0.040945
RPL31	0.040707
FOXA2	-0.040647
GBP2	0.039885
UBE2S	-0.039591
MID1IP1	-0.039346
IGFBP3	0.039249
OXR1	-0.039176
LGALS3BP	0.038894
MAPK6	0.038546
S100A5	0.038485
TNIP1	0.037479
NKX2-2	-0.037463
INSIG1	-0.036825
HSP90B1	-0.036431
CCL20	0.036299
GRAMD3	0.036116
MCM6	-0.035905
RPL27	0.035701
RPS13	-0.035676
PSMB9	0.035548
B2M	0.035523
BACE2	0.035513
RPS29	0.035251
NFKBIE	0.035112
UGDH	0.035007
ALDOA	0.034760
S100A10	0.034689
CSTF2T	0.034658
CLIC1	0.033980
NPDC1	0.033958
LRP4	0.033955
PSME2	0.033874
FAS	0.033769
SETD8	-0.033684
CGRRF1	0.033196
DTX2	0.033051
CKS2	0.033003
RCL1	0.032464
SNX11	0.032391
SLC39A1	0.031906
JAK2	0.031864
NDUFA1	0.031815
SMIM3	0.031617
OPN3	-0.031583
PRNP	-0.031044
BCL10	0.030942
LMBRD1	0.030792
PPP4R2	0.030658
RPL27A	0.030429
TMEM56	0.030399
PARP14	0.030151
MRPL22	0.030126
SQLE	-0.029944
CSRP2	-0.029827
PCBD1	-0.029823
CXCL16	0.029775
HADH	-0.029774
RBM3	-0.029333
CD164	-0.029306
ENO1	0.029181
CYP51A1	-0.028854
QDPR	-0.028368
RIPK4	0.028340
TRAFD1	0.028149
MCL1	0.028141
TRIM2	-0.028048
RPS19	0.027785
CYTB	0.027711
TMEM27	-0.027693
MAPRE1	-0.027654
PSAP	-0.027495
GHITM	0.027210
PBX3	-0.026728
GLRX3	0.026687
HNRNPH1	0.026675
PCNA	-0.026611
SPINT2	0.026366
RBM47	0.026332
RAB5A	0.026257
TMEM173	0.026247
HNRNPU	-0.026184
CHMP2A	0.026147
HMGCR	-0.026139
FTL	-0.026130
HSPA5	0.026040
MRPL18	-0.025922
ATP5C1	-0.025798
PLCXD3	-0.025728
RNF115	0.025724
TXNRD1	0.025575
ATP1A1	-0.025532
UBE2H	0.025424
DDX39B	0.025411
CABLES2	0.025316
TPT1	-0.025140
RASSF6	0.025132
NONO	-0.025027
HN1L	0.025016
TFRC	0.024932
FOXJ3	-0.024777
APP	-0.024769
LSR	0.024634
MAPT	-0.024607
SMPD3	0.024456
CHGB	0.024412
SAT1	0.024407
NPY	-0.024405
NR4A2	-0.024327
TMEM252	0.024160
TNKS1BP1	0.024064
PHC2	0.023981
UBE2QL1	-0.023914
ASPM	-0.023718
SEMA4B	0.023657
HSPD1	-0.023624
SPTAN1	-0.023601
GDE1	-0.023539
G0S2	-0.023427
COX2	0.023416
FAM98A	0.023300
TOMM7	0.023120
ND3	0.023119
MARK3	-0.023117
COX7B	0.023112
HSD17B12	-0.023079
NKX6-1	-0.023047
ACTG1	-0.023046
UBC	0.023028
DHX9	-0.022984
PDAP1	-0.022932
TYK2	0.022891
RPL10	0.022887
RPL13A	0.022868
ATP5G3	-0.022820
IER3	0.022755
HMGCS1	-0.022721
BEX4	-0.022629
DNAJC6	-0.022614
RNF14	0.022506
CCNH	0.022482
RPS20	0.022343
G3BP1	0.022284
CDC42EP3	0.022225
RPS25	0.022179
TIAL1	0.021960
RAD21	-0.021771
SUN2	0.021744
GNAS	-0.021708
CHCHD10	-0.021681
PRKAR2B	-0.021675
FNDC3B	0.021607
CEBPG	0.021599
CYCS	-0.021594
LRP11	0.021591
DHCR24	-0.021569
NINJ1	0.021546
RPL35	0.021499
RPL23	0.021475
PRDX1	-0.021313
GRINA	0.021304
FAM135A	-0.021292
ICAM1	0.021252
NRSN1	-0.021188
PSMB2	0.021156
RPLP0	0.021101
DTX3L	0.020953
PTGES3	-0.020872
FAM115C	0.020802
IL13RA1	0.020781
FAU	0.020612
PPP1CA	-0.020522
FUCA1	0.020471
SLC2A2	0.020469
ISG20	0.020415
STAT3	0.020343
ATP8B1	0.020200
RTN3	-0.020164
DDIT3	0.020131
CORO1C	-0.020114
IGF1R	0.020078
TAX1BP1	-0.019983
KDELR1	-0.019968
LASP1	0.019748
NDUFB6	-0.019682
FAT1	0.019666
SLC25A5	-0.019654
PARP8	0.019652
NPM1	-0.019605
KIT	-0.019585
PRPH	-0.019556
CCND2	-0.019522
LMO4	-0.019471
UBQLN2	-0.019471
SNRPD3	-0.019395
RASSF3	0.019346
ENC1	0.019335
UBE2E3	0.019203
ARRDC1	0.019051
CCNA2	-0.018994
PPP2R2B	-0.018814
EFCAB14	0.018709
SSBP3	0.018691
PDCD5	-0.018670
CCT4	0.018654
TSHZ1	-0.018637
ENTPD3	-0.018634
SEZ6	0.018610
SLMO2	-0.018579
WRNIP1	0.018569
CNBP	0.018565
ATP5G1	0.018564
RPS5	0.018561
TSPAN3	-0.018503
MAP2K3	0.018475
FAM111A	-0.018428
PLEKHM1	0.018349
H2AFZ	0.018300
PHTF2	-0.018236
GTF2IRD1	-0.018234
SHFM1	0.018227
CCDC61	-0.018197
DDX26B	-0.018172
ELF3	0.018169
RPS24	0.018166
STX6	0.018160
RHOA	-0.018149
HS2ST1	0.018083
RRM2	-0.018057
CHGA	-0.017954
AKR1A1	0.017945
GDAP1	-0.017870
PSMB4	0.017830
NUP205	-0.017799
MFN2	0.017723
TRIT1	0.017681
TM2D1	-0.017660
HDAC2	-0.017657
RTN4	-0.017652
NAP1L5	-0.017650
HOPX	0.017597
GLUD1	-0.017595
MTMR14	0.017574
ACSL5	0.017572
PDIA3	-0.017460
CDK1	-0.017442
HDAC11	0.017429
CACNA2D1	-0.017358
IFI44L	0.017354
VLDLR	-0.017311
TRAF4	0.017257
TES	0.017209
AKAP7	-0.017184
ATP11A	0.017177
DUSP5	0.017130
SEC61G	0.017039
RPL17	0.017028
SEC24D	-0.017014
CCNG1	-0.016893
RAP1GAP2	0.016872
NEURL3	0.016837
GAPDH	-0.016813
LPPR4	-0.016753
KLHL7	-0.016688
DEK	-0.016638
USP3	0.016625
PPP1R15A	0.016575
USMG5	0.016529
ANKRD10	-0.016519
RCAN2	-0.016502
PNRC1	0.016497
TRIM35	-0.016493
SDF4	0.016468
NSMCE4A	-0.016382
ATF4	0.016380
DCAF7	-0.016371
IL15	0.016344
PDCD10	0.016329
RAPGEF2	-0.016313
NDUFA12	-0.016296
ADH5	-0.016294
DYNLL2	-0.016212
NT5E	0.016211
GLUL	0.016187
TXNDC15	-0.016178
EEF1E1	0.016175
RPL10A	0.016135
NDUFA4	0.016081
MKI67	-0.016062
ZMIZ1	0.015963
CCK	-0.015946
PCSK2	0.015941
MPND	0.015929
TMEM130	0.015898
SRSF1	-0.015897
VDAC3	-0.015860
RPL12	0.015841
HNRNPA0	-0.015832
RPS6KA6	0.015801
ID1	-0.015740
NUCB2	-0.015739
ATP6V1B2	-0.015735
GRN	0.015696
DAB2IP	0.015637
SNCB	-0.015610
RPS12	0.015598
PDE9A	0.015558
SLC11A2	0.015529
CDH1	0.015517
CEACAM1	0.015515
CITED2	0.015410
PPP1R14B	-0.015346
OXCT1	-0.015319
NEUROD1	-0.015275
RPS14	0.015227
PPIP5K1	0.015224
RPA3	-0.015222
CDK8	0.015219
ATP5H	-0.015206
SQSTM1	0.015203
PKDCC	0.015201
ETNK1	-0.015186
GUCY2C	0.015160
TRIM5	0.015133
LRRC73	-0.015111
CTSB	0.015106
RPL18A	0.015102
RAB3A	-0.015096
CNKSR3	0.015063
ARPC5	0.015011
GNB2L1	0.014993
CHIC1	-0.014988
LITAF	0.014988
NUB1	0.014971
MICU3	0.014965
EIF4A1	-0.014962
HMGN1	-0.014941
CIB1	0.014891
HTRA2	0.014875
TSR1	0.014861
PSMA5	0.014837
KIF20B	-0.014835
UBE2Z	0.014786
LY6E	0.014779
XBP1	0.014733
SUOX	-0.014697
ATP5A1	-0.014672
ATP2A3	0.014657
RPL21	0.014648
NRP1	0.014642
ZNF367	-0.014641
OGFR	0.014632
PREPL	-0.014626
IFITM2	0.014532
YWHAH	0.014425
SND1	0.014425
TJP3	0.014384
DHCR7	-0.014380
CASP4	0.014375
TMEM180	0.014364
CHCHD2	0.014362
NDUFB9	-0.014331
ATP5J2	-0.014275
RAB21	0.014261
GPSM2	-0.014247
GNB2	-0.014235
UMPS	-0.014203
GADD45B	0.014195
SSR4	0.014186
RAB6A	-0.014141
WDR6	-0.014125
CIC	-0.014103
RNF10	-0.014037
USP14	-0.014028
PGRMC1	-0.014004
USP1	-0.014000
FIS1	-0.013997
FOPNL	0.013997
NSUN2	-0.013983
PMVK	-0.013978
ATP5F1	-0.013885
KRT7	0.013879
MDH1	-0.013831
OCIAD1	-0.013823
GRB14	0.013813
HNF1A	-0.013809
AGRN	0.013769
RPS21	0.013759
CHMP5	0.013721
BCKDK	-0.013716
FABP5	-0.013676
FRMD8	0.013659
GCGR	0.013560
PELI1	-0.013535
EMB	0.013514
GOT1	-0.013490
BTBD3	-0.013478
TFDP1	-0.013457
TFCP2L1	-0.013439
BTG3	-0.013425
EIF6	0.013417
SPCS3	-0.013409
BCAS2	-0.013376
PSME1	0.013358
ARF4	0.013357
IFNGR2	0.013351
LXN	0.013321
PARP1	0.013293
FHL2	0.013263
GLB1L2	0.013233
TBRG1	0.013207
DLG1	0.013176
PAK4	0.013168
PDE3B	-0.013127
MPV17L	0.013120
MYCBP2	0.013108
MATR3	-0.013106
XRN2	-0.013072
PAFAH1B1	-0.012983
CDK2AP1	-0.012952
AMBP	-0.012950
MBD1	0.012890
WBP11	-0.012889
HIVEP1	0.012871
PNMAL2	-0.012854
TNRC6C	0.012852
EID1	-0.012801
LDB1	-0.012788
GPRASP1	-0.012785
PSMB8	0.012741
YBX1	0.012713
TNKS2	0.012710
APLP1	0.012689
CALML4	-0.012637
CETN2	-0.012610
WARS	0.012592
LRRN2	-0.012578
PRRC2B	0.012543
MTMR7	0.012538
TMX1	-0.012538
SEC31A	0.012538
HNRNPA2B1	-0.012501
ATL2	-0.012501
EMC2	-0.012479
SH2B3	0.012473
COX17	0.012460
UQCR11	0.012457
TRMT112	0.012427
FGL2	0.012424
NMT1	0.012419