!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!drug_name	1-Piperonylpiperazine
!smiles	C1CN(CCN1)CC2=CC3=C(C=C2)OCO3
!pubchem_cid	94426
!cell_type	Hepatocytes
!organism	rat
!end_metadata
FADS1	0.106234
GPNMB	0.097240
HMGCS2	-0.086534
SLC10A1	-0.085346
CYP1A1	0.082836
RRAGD	0.078966
ACAT2	0.077166
G6PC	-0.071784
ANGPTL4	-0.069769
MSMO1	0.067756
IDI1	0.064047
SQLE	0.063524
ACSM5	-0.062276
BHMT	-0.060431
CYP8B1	-0.060061
LOX	-0.059275
BHMT2	-0.056259
HMGCS1	0.055581
LGALS3	0.055345
GLYAT	-0.054371
CYP51A1	0.054087
FDPS	0.052891
FTCD	-0.052230
PCSK9	0.052189
FDFT1	0.051952
BDH2	0.051803
IL1R2	0.051780
CSRP3	0.050649
FBP1	-0.049966
FAM111A	0.049236
TTC36	-0.049143
AASS	-0.048875
DPYSL2	0.048379
SAT2	0.047055
ABCB11	-0.046834
OTC	-0.046347
ACSM1	-0.044767
PLSCR1	0.044415
TM4SF4	-0.044360
LY96	0.044085
SULT2A1	-0.043686
CYP2E1	-0.043556
CD74	-0.043479
SLC37A4	-0.043465
MAFB	-0.043133
TMEM30B	-0.042808
MTTP	-0.042716
DDAH1	-0.042704
HSPB1	-0.042587
DPYD	-0.042309
DPYS	-0.041976
ENPP2	-0.041862
GADD45G	-0.041837
UAP1L1	0.041313
INSIG1	0.041106
COX6A2	0.040889
UGT2B17	0.040631
BBOX1	-0.040531
TTC39A	0.040343
FABP7	-0.039882
HSD17B7	0.039702
GCAT	0.039577
SLC27A5	-0.039509
ACOX2	-0.039505
ADH1C	0.039290
PQLC3	0.039268
CHAC1	0.039222
HYKK	-0.039191
GNMT	-0.038928
CA5A	-0.038675
LSS	0.038546
SCD	0.038530
HMGCR	0.038469
ALDH1A1	-0.038350
PHGDH	0.038233
RPRM	-0.038007
HAO2	-0.037747
YPEL2	0.037704
SLC13A5	-0.037643
KYNU	-0.037504
ECHDC1	0.037193
ROPN1L	0.036898
ANXA5	0.036857
PLIN3	0.036829
PAQR9	-0.036798
DMGDH	-0.036332
VEGFB	0.036234
PNPLA3	0.036182
SLC45A3	-0.035957
GPD1	-0.035764
GYS2	-0.035734
MTHFD2	0.035729
PDK4	-0.035633
PDIA5	0.035447
GSTK1	0.035387
FADS2	0.035247
ARHGAP22	0.035166
UPB1	-0.035165
DHRS3	-0.034993
IFT74	0.034989
CES1	-0.034840
APOBEC1	0.034831
SKAP2	0.034680
AGMO	-0.034441
FASN	0.034341
TCTEX1D2	0.034273
BHLHE40	0.034206
NPC2	0.034093
TLCD1	0.034082
NSDHL	0.033968
BCMO1	0.033950
CDKN3	0.033840
PEX11A	-0.033748
DHCR24	0.033735
ARMCX1	0.033732
MLLT11	-0.033622
ACSL3	0.033538
PXMP2	-0.033401
APOC2	-0.033317
ASNS	0.033163
GCKR	-0.032953
SLC6A12	-0.032734
AGXT	-0.032630
VCAM1	-0.032476
SEMA4A	0.032364
IRAK3	0.032318
WBP5	0.032301
LRP1	-0.032247
ZFAND2A	-0.031966
APOA2	-0.031959
FADS3	0.031882
HSPH1	-0.031720
HES6	0.031588
CLEC14A	-0.031544
CEMIP	-0.031512
PPAP2B	-0.031511
DNASE1L3	-0.031483
MLC1	-0.031463
AOX1	-0.031367
DUSP5	-0.031342
ARRDC4	-0.031039
LYVE1	-0.031022
FANCL	0.031003
DAO	-0.030973
GAMT	-0.030895
TBCC	0.030831
MMP15	-0.030778
CCRN4L	-0.030746
CYP7A1	-0.030686
BAX	0.030685
AGMAT	-0.030676
CRELD2	-0.030647
VNN1	-0.030591
AQP9	-0.030566
EHHADH	-0.030565
JUN	-0.030449
PMVK	0.030406
SULT1C2	0.030349
TM7SF2	0.030295
NMRK1	0.030260
MUM1	0.030233
TRIP13	0.030212
RSAD2	0.030079
RAB30	0.030030
THRSP	0.029958
ALDOB	-0.029927
SLC26A1	-0.029814
CPED1	0.029813
DECR2	-0.029770
MGMT	0.029763
TCEAL1	0.029712
FOSL1	-0.029586
TXNRD3	0.029558
ACAA2	-0.029489
NGFRAP1	0.029449
NAGK	0.029442
DPP7	0.029421
HSP90B1	-0.029360
PSAT1	0.029343
GJB2	-0.029265
FILIP1L	-0.029262
SLC25A25	-0.029142
MELK	-0.029102
PDIA4	-0.029024
IFIT3	0.028952
IGFBP3	0.028885
ELOVL3	-0.028863
SEC16B	-0.028854
PTER	0.028792
STARD4	0.028791
SLC4A4	-0.028773
FUCA2	0.028731
EEPD1	0.028690
FAM213A	0.028665
F2R	-0.028659
AMDHD2	0.028592
BHLHA15	-0.028591
ESM1	-0.028558
PAFAH1B3	0.028531
MASP2	-0.028520
DNAJB1	-0.028489
CLIC1	0.028222
SH2D4A	0.028175
TRHDE	-0.028085
WFDC2	0.028067
ITGB3BP	0.028064
KLF10	-0.027978
CNPPD1	0.027900
DCBLD2	0.027891
ATP6V1D	0.027843
DOK1	0.027598
XDH	-0.027292
CKAP2	0.027275
MGST3	-0.027176
CIB2	0.027159
INHBB	-0.027157
AADAC	-0.027103
RAB32	0.027057
AMPD3	0.027025
FBXO9	-0.026997
SDCBP2	0.026914
DCXR	-0.026897
MMD	-0.026881
PTRH1	0.026760
SLC27A2	-0.026647
CYP7B1	-0.026643
HSD17B6	-0.026599
ITPR1	-0.026549
ADORA2B	-0.026490
GPLD1	-0.026424
PKDCC	0.026404
TYMS	0.026275
GPX2	0.026252
CSTB	0.026246
CD63	0.026242
PMM1	0.026113
IRAK1BP1	0.025999
SERPIND1	-0.025992
NR1I3	-0.025974
IFI44L	0.025901
ARPC1B	0.025864
GSTA3	-0.025804
HSD17B2	-0.025793
SEL1L	-0.025766
ANGPTL3	-0.025720
GGH	0.025717
FABP5	0.025715
ASPA	-0.025650
PHYH	-0.025531
NAGS	-0.025530
LRP6	-0.025452
CTGF	-0.025446
ONECUT2	-0.025425
AHSG	0.025290
REEP3	-0.025238
GJB1	-0.025195
HEXB	0.025052
TTC8	0.025048
CPT1A	-0.024988
SERPINF2	-0.024986
CLSPN	0.024897
VIM	-0.024855
STEAP3	0.024853
DNMBP	-0.024813
DAK	-0.024810
PXMP4	-0.024793
CLDN1	-0.024785
FBXO30	-0.024698
PYCARD	0.024645
FST	0.024633
MEOX2	-0.024620
ANPEP	-0.024595
HNRNPH3	-0.024519
GRN	0.024503
TMEM256	0.024490
RAPGEF4	-0.024489
GADD45A	-0.024486
SVIP	0.024469
SDF2L1	-0.024466
CALR	-0.024307
EGR1	-0.024290
AACS	0.024202
CAMK1	0.024094
SOAT1	0.024090
IRS1	-0.024088
TMEM184C	0.024083
CCDC90B	0.024045
HSPA5	-0.024001
ACOX1	-0.023939
PROS1	-0.023932
IFIT2	0.023909
HBEGF	-0.023878
ATP6V0B	0.023877
MDH1	-0.023810
SC5D	0.023767
KLHL24	0.023750
DPM2	0.023691
LDHB	-0.023670
EPHA2	-0.023655
ARMCX3	0.023640
SEC14L2	-0.023593
NHEJ1	0.023573
TMEM39A	-0.023539
PDZK1	-0.023470
FMO5	0.023469
PSMB9	0.023467
CPEB4	-0.023424
MID1	-0.023417
NUFIP2	-0.023368
SLCO1B3	-0.023303
IDH2	-0.023295
NQO1	0.023293
PRSS23	0.023262
DUOXA1	0.023253
ELOVL2	-0.023187
ATP6V1F	0.023174
SERGEF	0.023166
COPRS	0.023130
STX17	0.023076
THYN1	0.022998
KLHL25	-0.022981
ZNF354A	-0.022919
ECI2	-0.022886
SHC4	-0.022878
C1QC	-0.022824
ABCC6	-0.022816
ZFAND2B	0.022795
MGP	0.022789
OSGIN1	-0.022789
EIF4EBP1	0.022762
ACY3	-0.022666
SLC1A2	0.022626
ACOT9	0.022616
PPCS	-0.022611
IL33	-0.022545
RASD1	0.022488
OPN3	0.022456
MCM4	0.022428
OPLAH	-0.022415
RUFY1	0.022392
SREBF1	0.022382
ENTPD5	-0.022284
SDS	-0.022242
IFITM3	0.022189
MPG	0.022186
HAAO	-0.022171
RBP7	-0.022153
DCN	0.022139
HTRA2	0.022136
PRDM1	-0.022114
PAOX	0.022105
PPM1H	0.022100
PECR	-0.022086
SPRR1A	-0.022051
IFIH1	-0.022042
RNASEH2B	0.022026
AVPI1	0.021964
SNX24	0.021935
FAM129A	0.021916
FAM118A	0.021914
SFN	0.021909
SLC7A11	-0.021784
HSPA4L	-0.021783
GPR64	-0.021760
MDM1	0.021756
NDRG2	-0.021741
TECPR1	0.021738
CEP152	-0.021735
TSPO	-0.021725
GDA	-0.021706
RPP40	0.021564
DAPK2	0.021510
TRIM59	0.021500
CASP7	0.021463
ALDOC	0.021448
TSPAN7	-0.021429
BBS7	0.021423
ASAH1	0.021422
CA14	-0.021420
KIAA1217	-0.021414
DNAJC18	0.021406
MIOX	-0.021334
HMOX1	-0.021323
SEPP1	-0.021289
TPD52	0.021282
ACAD11	-0.021271
CNDP1	-0.021220
SMIM22	0.021188
CCDC23	0.021161
ACADM	-0.021094
ANXA2	0.021092
LCAT	-0.021055
CMSS1	0.021036
MGAT2	-0.020991
GCFC2	0.020910
DSCR3	0.020871
ALDH1L2	0.020769
PRMT7	0.020761
FABP1	-0.020749
STX3	0.020742
RDH11	0.020702
SEC22B	-0.020696
SULT1E1	-0.020684
HOOK2	0.020649
SNX1	0.020626
CCNG2	0.020609
FUT1	0.020605
SLC30A1	-0.020599
GPT	-0.020598
LSM10	0.020589
ADSSL1	-0.020584
TOX	0.020576
DBNDD2	0.020568
GNPDA1	0.020541
HGD	-0.020531
NPRL2	0.020503
HINT3	0.020485
RNF115	0.020479
SERPINA6	0.020462
GALK2	0.020461
CEP83	0.020433
FAM46C	-0.020431
CSF1R	-0.020431
FMO1	-0.020400
SDR42E1	-0.020396
UAP1	-0.020362
TAF1B	0.020361
ABCG5	-0.020353
NGEF	-0.020343
ST8SIA3	-0.020334
SLC22A7	-0.020318
CRIM1	-0.020305
C9	0.020279
CDCA8	0.020277
LAMTOR1	0.020255
OSGEPL1	0.020165
DUSP19	0.020163
FOXA3	-0.020159
MRPL41	0.020084
MPPE1	0.020084
ARL6	0.020078
SH3GLB1	0.020061
GLOD4	0.020058
KCTD6	-0.020047
USP2	-0.020033
PPP1R3C	-0.020033
COMMD7	0.020032
SYTL2	0.020028
LZTFL1	0.020007
PON3	-0.019992
LRRC45	0.019988
PDP2	0.019971
ABCC2	0.019940
ACOT12	-0.019937
PFDN6	0.019910
CXCL3	-0.019904
HAL	-0.019872
CDS1	0.019851
PLG	-0.019846
FLCN	0.019819
CRP	0.019754
APOB	-0.019753
TEX264	0.019752
ENPP3	-0.019725
ACADVL	-0.019707
RHOQ	0.019694
MOSPD3	-0.019685
DTWD1	0.019657
AMY2B	0.019631
CYP1A2	0.019598
ERO1L	-0.019591
PLA2G15	0.019539
METRNL	0.019508
PIH1D2	0.019494
ACD	0.019472
MANBA	0.019444
PDE6D	0.019439
CST3	0.019350
NXT1	0.019349
DNASE2B	0.019340
ENTPD2	0.019328
ADCK3	-0.019310
DAP	0.019309
RMI1	0.019294
ABCB1	-0.019292
BBS2	-0.019284
CRY1	-0.019239
TUSC3	0.019208
HPS3	0.019199
SLC25A10	-0.019195
PSPH	0.019194
ACAT1	-0.019175
ATP8B1	-0.019166
SLC25A20	-0.019149
AP3S1	0.019132
RND3	-0.019131
ALDH18A1	0.019119
CREB5	0.019098
RELL2	0.019051
TYSND1	-0.019044