!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	17beta-estradiol
!ligand_id	CHEBI:16469
!cell_type	prostate gland
!organism	mouse
!end_metadata
EGFL6	-0.107003
IL33	-0.088327
RXFP2	0.077625
PGR	0.076851
CA12	0.072404
KDR	-0.068762
DKK2	0.068683
FMO2	-0.066550
SPOCK3	0.064833
ADH1C	-0.060811
H19	-0.060462
IGFBP3	-0.060357
LRAT	-0.059968
GLP1R	0.059346
EMCN	0.058852
SFRP4	-0.057761
ITM2A	-0.057369
RGS4	0.057307
CAPN6	-0.056998
SFRP1	-0.056445
SPRR1A	0.055604
SLC27A6	-0.055059
NRK	-0.053882
GPR64	-0.053649
FGF18	-0.053388
TRPC6	0.052767
PI15	0.052066
IGFBP4	-0.051973
ANGPT2	0.051834
GLRB	-0.051331
SLC5A7	0.051140
STRA6	-0.050868
A2M	-0.050651
CLDN11	-0.050297
NOV	-0.049224
NDUFA4L2	-0.049157
SULF1	-0.048534
FAM213A	0.048467
CYP11B2	0.047668
LRRC55	0.047216
ITGA1	-0.046895
SEMA3D	-0.046513
ISLR	-0.046420
SERPING1	-0.046419
GREM1	0.046087
SMARCA1	-0.046007
PRSS35	-0.045223
SLITRK6	-0.045197
CLIP4	-0.044562
TLL1	0.044536
OSTN	-0.044345
LCN2	-0.044339
PLCE1	-0.043562
PENK	-0.043513
SULT1E1	-0.042942
CDC42EP3	-0.042825
FGF7	0.042353
ANO3	0.041564
BTBD3	0.041376
GRPR	0.041045
FBLN1	-0.040971
GDA	-0.040613
PAMR1	-0.040547
HIST1H2AD	0.040376
GREB1	0.039844
TMEM100	-0.039838
PERP	0.039667
GPC3	-0.039511
ENPP3	-0.039344
B4GALNT2	-0.039319
IGFBP5	-0.038432
C1QTNF7	-0.038409
HIST1H2AK	-0.038194
NQO1	0.038075
OR5B17	-0.037838
FMO1	-0.037792
SCN7A	0.037626
HIST1H2BI	0.037540
COL14A1	-0.036978
LYZ	-0.036862
HAVCR2	0.036834
GJA1	0.036814
DCHS1	-0.036291
ITGA4	0.035860
SPON2	-0.035838
CD109	0.035775
EPPIN	-0.035675
NKD1	-0.035518
GATM	-0.035373
C1QB	-0.035236
LBP	-0.034967
TEDDM1	-0.034738
GALNT18	0.034668
FAM110C	0.034650
IGFBP2	-0.034594
CFH	-0.034489
NCOA4	-0.033969
BRINP3	0.033965
ITGBL1	-0.033833
C11orf82	0.033619
RGS5	0.033461
CRISPLD2	-0.033380
LILRB4	-0.033241
FAM180A	-0.033110
CCK	0.033091
NPY1R	0.033035
CDON	-0.032957
LPL	0.032954
PLCB1	-0.032902
SSTR1	0.032694
CNTN6	-0.032472
CKAP2	0.032451
CACNA1G	-0.032409
PDGFRA	-0.032329
MGP	-0.032093
TAGAP	0.032057
EDIL3	0.032054
SLC7A2	-0.032022
LGI2	-0.031898
CCND1	0.031892
ELAVL2	0.031887
PCDH11X	-0.031728
CRABP1	0.031606
LGR6	0.031307
SNRPF	0.031294
OR6C3	-0.031151
PAPPA	0.031088
GDPD2	-0.031044
NPR3	0.030893
PRUNE2	0.030880
APOE	-0.030740
ALDOC	-0.030721
CD44	0.030436
TSPAN13	0.030419
FXYD1	-0.030394
SLC16A12	0.030382
XAF1	-0.030009
GUCY1A3	-0.029973
TNFAIP8L3	0.029672
MAOB	-0.029652
SBSPON	-0.029639
BEND5	-0.029595
OR8G2	0.029480
TNFSF18	0.029307
MATN2	-0.029279
FAT3	-0.029100
GRAMD1B	-0.028897
FAM78B	-0.028871
PCDHB15	-0.028494
CD36	-0.028484
EGLN3	-0.028312
SLC2A3	-0.028244
TMEM176A	-0.028189
GPD2	0.028158
ATP1B1	0.028107
ADAMTS9	-0.028097
FAM150A	0.028089
ZBTB8B	0.028053
CHCHD10	-0.028049
C2orf88	-0.027972
ENPP1	-0.027922
SGK223	0.027874
CENPW	0.027803
LIPH	0.027790
GABRA3	-0.027696
ARHGEF26	-0.027664
MMD	0.027611
LUM	-0.027607
PTPRN	0.027599
KANK4	-0.027588
ACOT2	-0.027565
POSTN	-0.027479
KRT18	0.027408
C1R	0.027383
UGCG	0.027354
MEST	-0.027250
TAC1	0.027201
SLITRK4	-0.027195
MPEG1	-0.027188
TSPAN18	-0.027178
C8orf4	-0.027121
PRRG3	-0.027113
NUDT11	-0.027042
ITGA9	-0.026906
OR4C6	0.026862
RAMP3	0.026815
TNFAIP6	-0.026608
ZNF518A	-0.026596
SLC26A7	-0.026568
CD38	-0.026536
SLC8A1	-0.026513
CNTFR	-0.026184
OAS1	0.026147
C11orf88	0.026109
PLA2G7	0.026090
SHOX2	0.026060
EPHX1	0.025973
RDH10	-0.025938
KCNMA1	-0.025905
SPATS2L	-0.025899
TGFBI	-0.025884
OLFML1	-0.025853
TGM5	-0.025822
OR5L1	0.025723
BOC	-0.025670
MFAP2	-0.025624
ESM1	0.025510
FABP7	0.025507
POU5F1	0.025491
NIPAL1	0.025451
CRLF1	0.025424
IGF1	-0.025363
C1QC	-0.025251
MOXD1	-0.025104
TRO	-0.025089
SLCO1A2	0.025065
PLAU	0.025020
OR5I1	0.024915
TXNIP	-0.024905
ALOX12	-0.024868
MDK	-0.024755
OLFML3	-0.024742
PDK1	-0.024705
CD80	0.024588
HEG1	-0.024565
JAM2	0.024499
DEPDC1	0.024459
ASB5	0.024457
SCUBE1	-0.024423
STEAP3	-0.024363
PLA2R1	0.024345
NALCN	-0.024264
PI16	-0.024148
LRRC8D	0.024108
PRICKLE1	-0.024041
EPHA7	-0.024018
CDKN1A	0.024009
ITGA2	0.024006
GDF15	0.023976
TMCO2	0.023962
TMEM176B	-0.023792
SEMA3A	0.023764
COL15A1	-0.023761
NRP2	-0.023760
SNCAIP	-0.023732
GTSE1	0.023633
CLDN24	-0.023629
STC2	-0.023606
LYZL6	-0.023605
ACSS3	-0.023549
ISOC1	-0.023519
SPARCL1	-0.023473
HMGCLL1	0.023367
PRELID2	-0.023292
IGFBP6	-0.023273
RSPO2	0.023225
C10orf11	-0.023157
AICDA	-0.023149
MGAT4A	-0.023137
LAMA2	0.023124
KIAA0408	0.023096
IGSF10	-0.023058
DOK2	-0.023045
BMP15	0.022984
DNASE2B	-0.022944
GRIA4	-0.022880
CTSS	-0.022843
SYNPR	-0.022804
RPTN	0.022793
CA6	-0.022763
ASIP	0.022749
OR4S2	-0.022727
SCN4B	-0.022711
MPZL2	-0.022627
SPP1	0.022627
OR7A5	0.022561
CMKLR1	-0.022540
AGTR2	-0.022475
WNT4	-0.022460
CCL13	-0.022372
CDH19	-0.022316
OR5B3	0.022298
PARM1	-0.022218
ZNF420	-0.022208
VNN1	0.022179
FMOD	-0.022156
ARHGDIB	0.022125
JADE1	0.022092
C19orf45	0.022077
CHODL	-0.022066
UNC119	-0.022063
MEOX1	-0.021968
CLEC11A	-0.021834
HS3ST1	-0.021825
HIST1H3G	0.021802
HAS2	0.021800
NDST4	0.021798
CPED1	-0.021789
MSR1	-0.021760
ST6GALNAC5	0.021754
PRSS23	0.021747
DCLK2	-0.021736
ANGPTL7	0.021715
ALCAM	-0.021704
CXADR	-0.021664
SDPR	0.021659
LRRC15	0.021627
LY75	0.021587
KLHDC7B	0.021561
SAMD5	0.021545
ADAM30	0.021495
ELMO1	-0.021436
TFRC	0.021400
CCNB2	0.021400
LTBP1	0.021364
ALDH1A1	-0.021341
CPE	0.021331
MBNL3	0.021330
OR2A12	0.021303
BIRC2	-0.021269
NEO1	-0.021252
MGST1	-0.021207
DPYD	0.021182
KCNT2	-0.021158
CCNB1IP1	0.021153
SLC6A15	0.021115
DOCK10	-0.021108
ZNF443	-0.021073
LAMA4	-0.021047
SLC16A7	-0.021033
NTF3	-0.021016
MYO16	0.020991
THBS2	0.020942
KCNJ2	-0.020882
DPT	-0.020868
VSTM2A	0.020865
ANGPTL1	-0.020852
MKX	-0.020810
TMEM30B	-0.020801
NT5E	-0.020726
MYOT	0.020713
MMP11	-0.020699
DFNB59	0.020651
PCDH15	-0.020646
NFIA	-0.020629
RPP25	-0.020625
TM4SF20	-0.020615
IDI1	0.020612
RBP3	0.020555
SPRY2	0.020553
GJC3	-0.020545
DDIT4L	0.020517
C10orf71	-0.020429
MB21D2	0.020423
KRT16	0.020374
C1orf168	0.020296
MTM1	-0.020249
P4HA3	0.020218
PCSK6	-0.020217
B9D2	-0.020216
PIP5K1B	0.020196
HMGCS1	0.020186
NCKAP1L	-0.020145
RTP2	0.020139
INHBB	0.020084
ZNF804A	0.020031
NT5C1B	0.019991
LXN	0.019991
SUSD2	-0.019990
LRRTM3	0.019923
ZNF559-ZNF177	-0.019907
MMP3	0.019860
C20orf141	-0.019852
CD53	-0.019838
CDH3	-0.019828
STMN2	-0.019811
F11R	-0.019803
CCDC81	0.019746
THBD	-0.019739
TUBB4A	-0.019711
TEX36	0.019707
DHCR24	0.019669
CD3D	0.019655
CD68	-0.019654
C2orf73	0.019647
CD79A	-0.019642
NEK1	-0.019607
RBP1	-0.019596
CCDC115	0.019577
PRSS2	-0.019554
DIO1	-0.019551
CKS2	0.019514
KCNK5	0.019461
CYP27B1	0.019401
RNF148	0.019378
PRKAA2	0.019375
PCDHB8	-0.019364
PLK2	0.019352
TFPI2	0.019341
ARRDC3	-0.019313
CIB3	0.019304
PTGS1	0.019282
LOC730159	0.019201
BICC1	-0.019138
TXNDC16	-0.019126
CLCN5	0.019073
ETV1	0.019046
UQCRHL	0.019017
GPR174	-0.019010
DHRS7	-0.018984
TMEM178B	-0.018956
SVIL	-0.018954
SPINK5	-0.018933
KRT17	0.018900
PCSK2	0.018889
COL8A2	-0.018859
OR3A2	0.018843
STEAP1	0.018842
DYNC1I1	0.018825
FAM111A	0.018824
ZNF286A	-0.018801
LPAR1	0.018794
LTBP2	-0.018782
IFI44	-0.018773
ZNF14	-0.018751
PDE8B	0.018751
TMX4	-0.018733
SVOPL	0.018733
NR4A2	0.018732
TMEM97	0.018711
FAM46D	0.018707
CEMIP	0.018676
AMTN	0.018674
NDST3	0.018661
DUSP4	0.018660
C1QTNF3	0.018659
PCDHB16	-0.018631
NABP1	0.018617
DHRS3	-0.018570
C1orf94	0.018549
GSN	0.018538
PPP1R9A	-0.018499
S100A4	0.018474
ZAK	0.018457
TBX5	-0.018438
HSD17B13	0.018427
INSIG1	0.018421
TRAM1L1	0.018410
MFAP3L	0.018394
B3GALT2	-0.018392
ZNHIT6	0.018389
PTH	0.018384
DTD1	-0.018376
PEAK1	0.018360
PTPLAD2	0.018338
ELOVL4	-0.018309
PLLP	0.018294
RRAD	0.018293
NMS	0.018286
SIPA1L1	-0.018275
HS6ST2	0.018270
OR6C2	-0.018263
HSD17B7	0.018227
C5orf63	-0.018221
SLC24A1	-0.018213
TCF21	-0.018212
PTPRK	0.018211
CABLES2	0.018208
CPNE2	0.018189
TMEM255A	-0.018178
PARD3B	-0.018175
WT1	-0.018173
WNT2	-0.018156
KIF11	0.018147
MMP15	-0.018144
ARAP2	0.018114
EPHA1	0.018105
MLLT11	0.018104
PCDH19	0.018099
UCHL1	0.018089
RERG	0.018073
LDLR	0.018062
DACT1	-0.018034
SESN1	-0.018014
CCDC63	-0.018008
GRK5	-0.017981
ABCA1	-0.017979
B3GALT4	0.017944
LAPTM5	-0.017942
CLEC5A	-0.017934
ITIH5	-0.017931
ARHGAP26	0.017927
ZNRD1	-0.017927
LY86	-0.017921
MGARP	-0.017914
MYO6	-0.017895
ENPEP	-0.017884
TENM4	-0.017810
SPINT4	0.017744
MEF2C	-0.017738