!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Cobalt dichloride hexahydrate
!smiles	O.O.O.O.O.O.[Cl-].[Cl-].[Co+2]
!pubchem_cid	24643
!cell_type	MH1C1 liver cell line - 160 uM
!organism	rat
!end_metadata
SLC2A2	-0.090899
PIK3C2G	-0.088131
HPD	-0.087171
MIA	-0.084493
IGFBP6	0.082332
ALDH1A1	0.079630
DMRT1	-0.076877
GSTA3	0.076603
ALDH3A1	0.073564
DYNC2LI1	-0.072261
GNAT3	0.072249
CITED1	0.070114
COL9A1	-0.069634
SPTA1	0.068912
ENTPD5	0.067871
HMOX1	0.065155
PIR	0.063764
ITIH4	-0.062728
PTPRM	-0.061962
SLC38A4	-0.060638
C5	-0.059664
MAFF	0.057710
AQP8	-0.057305
CDH17	-0.057227
CREG1	0.055640
GCLC	0.054117
SLC7A11	0.053974
AOX1	0.053708
SLC17A3	0.053513
LPCAT1	-0.053121
ITIH3	-0.052656
FAM102B	-0.052102
ARL11	0.051908
ABCG5	-0.051198
KCNE4	0.050030
PTGR1	0.048872
SBSN	-0.048755
FGA	-0.048541
DIXDC1	-0.048247
PDE11A	-0.048034
DYNC1I1	-0.047622
DCXR	0.047300
NQO1	0.045617
TFF3	-0.045526
ITIH1	-0.045184
ADTRP	-0.044947
CNDP1	-0.044928
PLG	-0.044872
GYS2	-0.044849
MYLK	-0.044742
LMCD1	-0.044333
ANGPTL4	-0.044179
ADAMTS4	-0.043887
ZBTB7B	0.043769
SNN	-0.043661
GSTA5	0.043202
ABCG8	-0.043153
TGFB3	-0.043116
AKR1B10	0.042988
STEAP1	0.042877
CES1	0.042875
ABCC4	0.042505
ADH1C	0.042369
GSR	0.041841
LTBP1	-0.041564
SLC48A1	0.041420
ILDR2	-0.040780
RASSF6	0.040748
HMGCS2	-0.040613
CLDN2	-0.040396
ATP1A2	-0.040284
SERPINA11	-0.040137
UGDH	0.040058
RUFY1	-0.040026
MYH14	-0.039705
SERPINA6	-0.039584
MATN3	-0.039328
MBOAT1	-0.039136
TTR	-0.039029
AFMID	-0.038862
DNASE1L3	-0.038853
EHF	-0.038563
NPAS2	-0.038317
NR0B2	-0.038142
FAM129A	-0.037946
AZGP1	-0.037929
SLC2A1	0.037797
FUT4	-0.037518
KCNE3	0.037481
SPP2	-0.037445
ELOVL6	-0.037394
CSPG5	-0.037287
BCAS1	-0.037215
PROC	-0.037174
GCLM	0.036994
FASN	-0.036780
TSKU	0.036445
TXNRD1	0.036339
VTN	-0.036116
GNG3	-0.035922
FILIP1L	-0.035658
TPPP	0.035657
VCAN	-0.035384
P4HA1	0.035301
TNFRSF12A	-0.035243
ESYT3	-0.035188
ABCB1	-0.035089
ABCC3	0.034765
MACROD1	0.034756
AREG	-0.034706
SCCPDH	0.034656
MAP2K3	0.034597
EPB41	0.034537
CASQ1	-0.034485
MYOF	-0.034415
TMEM205	0.034391
TGM2	-0.034230
OLFML3	-0.034228
BCS1L	0.034180
GPX1	-0.034138
ABCB6	0.034136
ALDOA	0.034068
KIFC3	-0.034010
CP	-0.033966
FMO1	0.033864
TBC1D5	0.033719
NAMPT	0.033615
PAK1	-0.033415
FN1	-0.033301
HP	-0.033297
LIMD2	-0.033290
UGT2B17	0.033221
CHP1	-0.033039
WNT4	0.032693
PLEKHB1	-0.032500
SHPK	0.032453
PDE4DIP	-0.032398
PSCA	-0.032205
CLIP1	0.032202
PGC	-0.032105
BLVRB	0.032045
PLAT	-0.032001
KNG1	-0.031933
ERO1L	0.031862
CPEB1	0.031764
TRIM2	-0.031748
DHCR24	-0.031697
TSGA13	-0.031532
RSAD2	-0.031523
COQ6	0.031491
ID4	-0.031224
ANKRD37	0.031015
MAN2A1	0.030751
YPEL4	-0.030596
SERPINA10	-0.030569
SPO11	-0.030525
ADH7	0.030515
PTPRG	-0.030465
HACL1	-0.030412
SV2A	-0.030390
AIM1L	-0.030217
RCAN2	0.030205
RTN4R	0.030187
PKDCC	-0.030185
CXADR	-0.030106
ADAMTS1	0.030059
UGGT1	0.029991
MMP7	-0.029920
HAP1	0.029905
ME1	0.029564
TMEM50B	-0.029562
ALCAM	0.029490
C8A	-0.029401
SLC17A1	0.029345
JMJD8	-0.029177
GPR88	-0.029121
THEM5	-0.029105
THADA	-0.029032
CTGF	-0.028965
AK4	0.028727
SRXN1	0.028721
CLIC5	-0.028717
STYXL1	0.028671
RND1	-0.028665
PFKL	0.028559
FAM72A	0.028548
CAMKMT	-0.028479
PALMD	-0.028430
RND3	0.028341
CYR61	-0.028223
HSPB6	0.028218
ITIH2	-0.028217
SEMA6A	0.028182
TRPM3	-0.028168
BHLHE40	0.028096
DDC	-0.027980
TBCE	0.027888
CYP1A2	-0.027855
PLA2G16	-0.027844
RBP4	0.027840
SNX10	0.027824
CAV2	-0.027781
NRP1	-0.027769
CROT	-0.027654
SHANK3	-0.027629
SYTL3	-0.027556
RHPN2	-0.027548
CHD3	-0.027508
CDYL2	0.027476
CXCL10	0.027390
PDGFA	-0.027216
MANSC1	-0.027197
EPHX1	0.027187
KDM3A	0.027184
TNFRSF9	-0.027116
SH3BP5L	-0.027067
PDK1	0.027043
RTP4	-0.026953
CHPF2	0.026926
PAQR8	-0.026902
CIDEC	-0.026871
HDDC3	0.026856
PRKAG3	0.026762
UBE2C	0.026710
LMNB2	0.026523
FAM110B	0.026517
KIF18B	0.026433
HTRA1	-0.026423
CTSD	0.026375
CD55	-0.026313
LYST	0.026278
PQLC1	-0.026175
PTGES2	0.026156
GPR126	-0.026151
HIGD1A	0.026057
TSPAN17	0.026043
EIF2B3	0.026038
DECR2	0.025851
ANKRD1	-0.025755
CDKN2D	0.025752
ANXA4	-0.025737
TPMT	-0.025662
C8G	0.025648
ABCB4	-0.025640
CDH3	-0.025632
SLC3A1	-0.025622
HGFAC	-0.025591
TDRP	-0.025590
FAM83D	0.025552
LIM2	-0.025463
PIGR	-0.025455
ZFAND2A	0.025425
RWDD2A	-0.025388
SLC22A18	0.025386
PKIA	-0.025326
CPLX2	0.025011
FBXO5	0.024920
GAMT	-0.024919
HDAC11	-0.024906
TESC	-0.024894
HIST1H2BJ	-0.024875
ACOT2	-0.024831
CCDC96	0.024830
KDSR	-0.024773
SERPINB9	-0.024740
PYCARD	0.024709
PRND	-0.024706
MXD3	0.024671
CRYAB	-0.024615
UBE2O	0.024603
ARHGAP22	-0.024540
NEDD9	-0.024537
MYZAP	-0.024402
CGRRF1	0.024307
FOXM1	0.024294
BACH1	0.024237
BAMBI	0.024217
TIFA	-0.024204
TNIK	0.024198
PORCN	-0.024186
CCRL2	0.024184
NR1D1	-0.024164
JUN	-0.024164
CXCR1	-0.024157
TMCC3	-0.024156
B4GALNT1	-0.024039
GSTM1	0.024034
SLC7A7	-0.023996
KIF12	-0.023964
DNAJC12	0.023957
NEDD1	0.023954
CPM	-0.023934
RABL3	-0.023765
LDHA	0.023757
SAPCD2	0.023724
MYO16	-0.023716
SPP1	0.023665
ALDOB	-0.023646
LRP2	-0.023644
CUBN	0.023598
MARC1	0.023588
UGT2A1	0.023581
CREM	-0.023431
INHBB	-0.023393
LNX2	0.023372
APLN	0.023370
ACACA	-0.023300
HMMR	0.023230
STAU2	-0.023228
HBEGF	-0.023202
RUSC2	0.023156
EEPD1	0.023135
L3MBTL2	0.023134
NUSAP1	0.023127
FAM227A	-0.023068
VNN1	-0.023062
SQSTM1	0.023051
GSTM5	0.023014
SH3TC1	0.023012
HERC6	-0.022967
SCPEP1	0.022952
AGMAT	-0.022922
PGK1	0.022918
DIO1	-0.022903
HECTD3	0.022859
AHSG	-0.022800
G6PC	-0.022785
ORC1	-0.022750
HPSE	0.022726
PTGS1	0.022696
SEMA5A	-0.022681
MAP1LC3A	-0.022521
DDIT4	0.022501
TENM3	-0.022499
KLF5	0.022488
SULT1C2	-0.022479
TXK	-0.022473
RBP7	-0.022443
CXCR3	-0.022441
SHISA4	-0.022428
GADD45B	-0.022397
HSPA2	-0.022340
RTN1	0.022320
TFRC	0.022313
PRR15L	-0.022304
VEGFA	0.022280
TNFAIP6	-0.022267
C2CD5	-0.022261
CCDC141	-0.022195
ZKSCAN5	0.022145
CPB2	-0.022130
DUSP6	-0.022127
PCCA	-0.022099
FOS	-0.022092
ADAMTS7	-0.022076
SYTL2	-0.022071
KIF26B	0.022037
RASL11B	-0.021957
UNC5CL	-0.021941
ARL6IP6	-0.021916
CFB	-0.021908
TRIM16	0.021901
CYB561D2	-0.021865
COL15A1	0.021828
TMOD4	-0.021827
ANPEP	-0.021817
GCKR	-0.021803
CRYL1	0.021788
COL4A3BP	-0.021784
MYL4	-0.021754
INPP5A	-0.021729
APCS	-0.021701
P2RY2	0.021679
NCOA7	-0.021675
PRICKLE1	0.021653
CCDC125	-0.021644
PSMB3	0.021633
F5	-0.021632
NOSTRIN	-0.021628
KEAP1	0.021610
PBX3	-0.021592
HSPH1	-0.021589
CALML4	-0.021574
RBKS	-0.021548
WEE1	0.021539
ZNF654	0.021483
PSMD5	0.021475
GBE1	0.021448
INHBE	-0.021420
TOP2A	0.021413
CYP26A1	0.021404
CCDC77	0.021340
SLPI	0.021307
BARD1	0.021289
CNTLN	0.021269
HIST3H2A	-0.021260
GPHN	0.021252
FRS3	0.021241
GPNMB	-0.021235
ACOX2	-0.021216
CSRP1	0.021192
VPS4A	0.021185
PPIP5K1	0.021150
ERCC1	0.021132
ICAM1	-0.021112
ARHGAP11A	0.021102
BNIP3	0.021101
OCRL	0.021056
PFKFB1	-0.021025
WNT16	0.021010
PTPRE	-0.020987
PGRMC1	0.020973
ENDOU	0.020968
NMRK1	0.020955
WFDC1	0.020923
KRT36	-0.020917
KIF20B	0.020911
ISPD	-0.020894
RHOH	-0.020857
CKAP2	0.020853
KIF22	0.020753
TRAIP	0.020695
PSPH	-0.020687
TCEAL8	0.020686
CCDC80	-0.020630
SSX2IP	0.020616
HSF4	0.020613
SSBP3	0.020571
BLNK	-0.020540
ASF1B	0.020539
SOD2	0.020535
GNA14	-0.020528
ALDH1L1	0.020527
DGKA	-0.020490
SLC40A1	0.020488
MOCS2	0.020482
KIFC1	0.020479
NAT8	-0.020439
SLC22A3	0.020419
CDS2	0.020394
C2CD3	-0.020317
ZNF416	0.020211
MGST2	0.020183
CXCL2	-0.020174
RASGRP3	-0.020168
WWC1	-0.020135
PPARGC1B	0.020129
OLFML1	0.020095
NCOA4	0.020090
TROAP	0.020086
TMEM106A	-0.020049
CDC14A	-0.020041
CHDH	-0.020013
FAM171B	0.019941
ACKR3	-0.019894
FZD8	0.019893
ITPR1	-0.019886
OSGIN1	0.019882
XRCC6BP1	0.019880
ABR	-0.019854
POLD4	-0.019845
AURKA	0.019822
HTATIP2	0.019820
ADH5	0.019806
PBK	0.019799
EGLN3	0.019777
RAD52	0.019741
ARL4C	-0.019714
C9	-0.019638
ACYP1	0.019629
NUDT12	0.019618
UBE2T	0.019615
ETNK1	-0.019589
PFDN5	0.019576
TINF2	0.019571
CPA2	-0.019564
MMP19	0.019493
MAP3K8	-0.019485
PLIN2	-0.019468
CAPN6	-0.019435
HSPB8	0.019431
SNED1	-0.019409
LAMA3	0.019395
PLS1	-0.019391
TPI1	0.019382
ACO1	-0.019362
TRMT10A	-0.019356
SMS	-0.019332
MYH10	-0.019238
WIF1	-0.019208
TOM1L1	-0.019175
HOXA5	0.019160
SELM	0.019116
TGFA	0.019116
MYOM1	-0.019059
VPS13C	-0.019059
ZBTB4	-0.019031
DEPDC1B	0.019025
ESPL1	0.019021
POSTN	-0.019016