!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!cell	heart
!perturbation	isocitrate dehydrogenase 2 R140Q mutant
!disease	cardiomyopathy
!end_metadata
ANKRD1	0.208021
ACTA1	0.187794
PDK4	0.158559
SFTPC	0.136874
CTGF	0.125529
MYL4	-0.125143
THBS1	0.113536
CHRM2	-0.102738
ABRA	0.101199
SERPINE1	0.097343
ENO3	-0.095712
TUBA4A	-0.092998
RGS5	0.091179
NUAK1	0.089965
ATF3	0.088361
CES1	-0.087245
COX7A1	-0.085203
PAM	0.084984
FHL2	-0.083490
LY6E	0.081183
PPARGC1A	0.079532
XIRP1	0.079278
PICALM	0.078059
FLNC	0.075557
ADAMTS1	0.075091
IGFBP7	0.075033
HERPUD1	-0.074630
GSTK1	-0.073813
CYR61	0.072947
DGAT2	-0.072831
TNNI3	-0.071806
ETFB	-0.068114
UGP2	0.067661
SERINC3	0.066854
XIRP2	0.065643
HADH	-0.064960
CASQ1	-0.064760
CS	-0.064243
CACNA2D1	-0.064108
PTGDS	0.063045
PPIP5K2	-0.062731
CLU	-0.061950
BTG2	0.060237
FABP4	0.059865
APOBEC2	-0.058518
ART3	-0.058345
OTUD1	0.058092
AGTPBP1	-0.057859
PDLIM5	0.057255
SPARC	0.057133
TCAP	-0.056907
TMEM182	-0.056685
GSN	-0.056573
TECRL	-0.056326
MYL2	-0.056214
NPPA	-0.055996
PFKM	-0.055991
UQCRC1	-0.055934
JAM2	0.055884
SORBS2	0.054429
GOT1	-0.054122
SPARCL1	0.053644
RCAN1	0.052595
CANX	-0.052163
IVD	-0.051653
CD36	0.050681
ANXA5	0.050062
HSPB7	0.050002
S100A10	0.049819
MYLK4	0.049688
IFNGR2	-0.049570
BDH1	0.049566
ANGPTL7	-0.049562
PYGM	-0.049353
RPL3L	-0.049224
ENAH	0.048755
CORIN	-0.048743
TNNI3K	-0.048633
CAV1	0.048347
CDH5	0.048295
NDUFB9	-0.048103
COX6A2	-0.047854
NDUFV1	-0.047850
DNAJB4	0.047431
PIK3R1	-0.047422
COMT	0.047406
GSTP1	-0.046865
ZNF106	-0.046705
OGN	-0.046680
GOT2	-0.046605
GBAS	-0.046584
ACOT2	0.046537
ACTB	0.046380
ATP1A2	-0.046380
LRRC8C	0.045681
TUBA8	-0.045665
SLC38A2	0.045441
KIF5B	0.045389
HBEGF	0.045271
CYTL1	-0.045033
AKR1B1	-0.044541
LMOD2	0.044337
FITM1	-0.044029
TXNIP	-0.043893
CST3	-0.043815
DUSP1	-0.043682
EEF1A2	-0.043674
AQP1	0.042408
DUSP7	-0.042290
NAMPT	-0.042289
B2M	0.042261
GABARAPL1	0.042068
GHR	-0.041563
LAMB2	-0.041491
NUDT4	0.041469
CCND2	0.041171
SGCA	-0.040996
GPR56	0.040951
UBC	-0.040891
PPP2CA	0.040859
NR4A1	0.040783
CTSD	0.040645
PPIF	-0.040147
HHATL	-0.040099
CALR	-0.039870
PPP1R3C	0.039576
ELTD1	0.039348
MYL7	-0.039273
FAM96A	0.039006
PALLD	-0.038957
PRKAR1A	0.038925
TP53INP2	0.038913
HSPA5	-0.038878
CHPT1	-0.038835
MDH2	-0.038544
ASB2	-0.038295
EGLN3	0.038233
NR4A3	0.038190
TMTC1	-0.038183
NDUFS4	-0.038118
PRUNE2	0.038116
MAOB	-0.037994
CDKN1A	0.037817
ADH1C	0.037549
POPDC2	0.037341
CRAT	-0.037324
S100A1	0.037251
ATP5J2	-0.036902
MB	-0.036376
CA3	-0.036002
PSAP	-0.035671
NDUFA8	-0.035159
APLP2	0.035021
ANTXR2	-0.034694
COX7B	-0.034677
MGST3	-0.034264
HSPA9	0.034052
EIF4A1	0.034013
UCK2	0.033927
SFTPB	0.033576
ACTG1	0.033537
HSPB8	0.033438
PTPRB	0.033426
ISCA1	-0.033407
FSD2	-0.033335
TSPAN7	0.033179
RPS5	-0.033153
NCEH1	0.033074
MYL3	-0.032956
ESAM	0.032834
ACSS1	-0.032706
LPL	-0.032623
AFG3L2	0.032428
KIAA1551	0.032425
IDH3G	-0.032269
HOPX	-0.031846
TRAK2	0.031756
MYBPC3	0.031584
AS3MT	-0.031583
SLC20A2	-0.031527
PTTG1	0.031442
NDRG2	-0.031403
PGAM2	-0.031165
PRNP	0.031040
TMEM65	-0.031029
ATPIF1	-0.031008
GATA6	-0.030913
PTP4A1	0.030698
GPR116	0.030562
SH3RF2	-0.030529
HIF1A	0.030354
LRRC10	-0.030276
SFTPA1	0.030273
PPP1R3A	-0.030220
SLC25A5	0.030113
MYOZ2	-0.030070
HFE2	-0.029518
RBP7	-0.029364
PABPC1	0.029352
SNTB1	0.029314
UQCRQ	-0.029205
RYR2	-0.029116
TFPI	-0.029007
ALDH2	-0.028987
MYLK3	-0.028937
CDS2	0.028921
NABP1	0.028864
VWA8	0.028845
IFITM2	0.028798
TIMP4	0.028586
NDUFB6	0.028517
CYYR1	0.028441
IVNS1ABP	-0.028348
LCN2	0.028219
DHRS7C	-0.028164
RPL10A	-0.028071
CD34	0.028041
DBT	-0.027995
LRRC14B	-0.027937
HDLBP	-0.027817
SMIM20	-0.027799
ADAMTS9	0.027724
SLC16A1	-0.027668
SDHC	-0.027654
SLC4A3	-0.027455
ASB14	-0.027450
NDRG4	0.027410
PERP	-0.027350
RRAS	0.027317
VIM	-0.027282
PCDH7	-0.027226
SPTAN1	0.027183
LDHA	-0.027123
PARK7	0.027010
HSP90B1	-0.026955
TMOD4	-0.026947
SF3B1	0.026939
CLIP4	-0.026925
RBM24	-0.026896
MYO10	0.026881
WFS1	-0.026758
FYCO1	-0.026669
MUT	-0.026596
ELL2	0.026461
COQ3	0.026421
HIPK1	0.026342
C10orf107	-0.026325
NQO1	0.026309
PINK1	-0.026265
SLC9A3R2	0.026191
AK1	-0.026188
CD300LG	0.026185
KCNJ3	-0.026111
SLFN5	0.026108
MYOM2	-0.025969
PHKA1	0.025894
PDK2	-0.025835
NDUFA3	0.025799
ISOC1	-0.025791
GNB1	0.025747
CLTC	0.025704
HSPB6	0.025603
SLC31A2	-0.025466
TXN	0.025438
DPT	-0.025398
AKAP2	0.025354
CFL1	0.025353
CYFIP2	0.025294
IL13RA1	-0.025198
DHDH	-0.025186
MPV17	-0.025075
VDAC1	-0.024966
SSPN	-0.024965
TIMM23	0.024958
NDUFAF1	0.024953
ITGA6	0.024921
ARL8A	0.024857
IDH2	-0.024787
DCN	-0.024779
KCNJ5	-0.024778
ACTA2	-0.024755
APP	0.024748
ACTN4	0.024712
SLC25A3	-0.024686
TFRC	-0.024657
PHYH	-0.024562
PPM1K	-0.024447
KLHL38	-0.024445
SPTBN1	0.024303
FXYD5	0.024240
HSD17B7	0.024229
LYVE1	-0.024183
RPL12	-0.024174
MSRB1	0.024127
CCDC141	-0.024108
PSME1	-0.024102
PYGB	-0.024075
FBLN1	-0.024005
SDCBP	0.023922
TMEM189	0.023905
IDH3A	-0.023741
LAMA2	-0.023726
RPS15	-0.023711
CA4	0.023489
POLR2L	0.023418
LDHB	-0.023401
IFITM3	0.023276
CSDC2	-0.023263
PARM1	-0.023078
CNIH4	0.023067
GRB14	-0.023007
RBM3	0.022950
PSME4	-0.022935
SLC44A2	-0.022931
ITGA5	0.022889
CHCHD10	-0.022858
CDV3	0.022828
ACADL	0.022824
EIF4G1	0.022726
ATP5C1	-0.022690
ROMO1	0.022652
PKIA	-0.022646
PPM1A	0.022624
ATF7IP	-0.022591
USP2	-0.022527
KLHL41	-0.022475
TNFRSF12A	0.022472
GLG1	-0.022457
ACO2	-0.022412
TAX1BP3	0.022389
EIF4G2	-0.022380
RPLP0	-0.022360
GHITM	0.022358
REEP5	-0.022238
PLA2G5	-0.022214
TRIM63	-0.022172
MICAL2	0.022148
PLXNA2	0.022035
RPL18	-0.021977
ACAA2	0.021917
LRRC8A	0.021902
OSMR	0.021866
BCAT2	-0.021846
ITGA1	0.021801
TTN	-0.021783
THRSP	0.021636
EMC2	0.021628
CTSV	0.021603
XDH	0.021597
PRELP	-0.021580
NARS	0.021567
TECR	-0.021512
COX6B1	0.021506
BNIP3	0.021465
NDUFB8	-0.021425
CDH13	-0.021422
COA5	0.021407
FKBP5	0.021376
TP53I11	0.021361
EGR1	0.021352
TRIM55	-0.021308
GPX4	0.021299
STRIP2	-0.021271
TMEM242	-0.021142
TUBA1B	-0.021077
NDUFB5	-0.020913
TMBIM4	0.020873
ARHGAP20	-0.020859
CTNNA1	-0.020858
SESN1	-0.020833
RAP1B	0.020818
TFB2M	0.020776
ADCY6	-0.020771
GPC1	-0.020547
UBE2D3	0.020539
MDH1	-0.020520
ISCU	0.020489
BSG	0.020472
GPR22	-0.020459
HADHA	0.020456
PRDX1	0.020450
MPI	-0.020446
TMEM50B	-0.020406
TSPAN13	0.020397
TMEM106B	-0.020337
DLD	0.020335
FH	-0.020305
EDNRB	0.020266
MLF1	-0.020247
IFNGR1	0.020202
ZCRB1	0.020127
NDUFA4	0.020079
FXYD1	-0.020078
CLYBL	-0.020019
NUS1	0.019998
AQP7	0.019900
PPP2R3A	-0.019878
PEX19	0.019853
PENK	-0.019847
CAPZA2	-0.019798
PSMD2	0.019786
ATP6V1D	0.019714
TMEM144	0.019670
ECHDC2	-0.019650
CSRP3	-0.019642
SYNGR2	-0.019615
SLC25A34	-0.019577
GLUL	0.019556
NDUFB4	-0.019551
C3	-0.019486
C7orf55	-0.019462
PRDX2	-0.019425
SLC34A2	0.019351
UCP2	0.019342
CRIPT	0.019245
TNNC1	-0.019242
LRTM1	0.019241
TBX5	-0.019199
LRRC2	0.019144
SEMA7A	0.019138
SLC27A1	-0.019128
ARHGEF12	0.019092
CD93	0.019074
HNRNPAB	0.019058
FAM117B	0.019009
CAT	0.019003
GAPDH	0.018953
RHOA	0.018938
FAM134B	0.018922
TPT1	-0.018902
SCD	-0.018865
NOP10	0.018857
SLC2A4	-0.018830
BLOC1S1	-0.018799
CAP2	-0.018778
ASB15	-0.018771
GSTM2	-0.018748
VTN	0.018730
PPFIBP1	0.018652
VEGFA	0.018611
UQCRHL	-0.018583
ECHS1	-0.018575
CHURC1	0.018568
CDH2	-0.018550
C4orf29	-0.018528
PITPNA	0.018512
ATP1B1	-0.018477
FBXO40	0.018475
AES	-0.018401
ADRA1A	-0.018380
ABLIM3	0.018373
APOE	-0.018372
DSP	-0.018368
MYL1	-0.018356
RAB12	-0.018329
ATP5H	-0.018296
GNAS	-0.018288
ATP5O	-0.018267
RTN3	0.018124
MRPL3	0.018118
ADIPOR2	0.018066
MPC1	-0.018062
PLIN3	-0.018046
ANKH	-0.017965
NFIX	-0.017957
LGI1	-0.017950
IMPACT	0.017939
TTC12	-0.017876
RAB10	-0.017867
GSTM1	-0.017801
EPAS1	0.017768
TMEM47	-0.017755
POLDIP2	0.017746
ATP5D	-0.017740
ZNF706	0.017630
ADPRHL1	0.017620
S1PR1	0.017601
OXA1L	-0.017569
SLC47A1	-0.017559
ME1	0.017559
PRDX6	0.017558
ARPC1B	0.017520
FAM107A	0.017517
PSMB10	0.017515
FNDC5	-0.017505
DUSP3	0.017412
RTN2	-0.017410
ATP5G1	-0.017396
AGL	-0.017363
JUP	-0.017362
DNAJA2	0.017353
NFIL3	0.017323
ASB11	-0.017230
RPS10	-0.017190
TMEM141	-0.017182
RPL10	-0.017154
NDUFV2	-0.017118
TESC	-0.017085
C10orf71	-0.017065
RPL9	-0.017053