!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Doxorubicin
!smiles	CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
!drugbank_id	DB00997
!pubchem_cid	31703
!cell_type	A673
!organism	human
!end_metadata
HIST1H2BK	0.165957
HIST1H2BD	0.127361
NELL2	-0.120162
KRT18	0.111125
ASNS	-0.102449
ARL6IP1	0.090640
CES1	0.090205
MMP1	0.088608
YPEL5	0.088155
TMSB10	0.086764
HSPB1	0.085341
AKAP12	0.083503
HIST1H2AC	0.081866
GARS	-0.080215
MLLT11	-0.079884
FDFT1	-0.072872
MKNK2	0.071451
TUBB	-0.066949
PSMA1	-0.066949
EIF4EBP1	-0.066779
OAT	0.066306
ANP32B	-0.066253
IARS	-0.065043
EDF1	-0.064354
S100A10	0.063745
PSMD14	-0.062441
ANXA1	0.062226
NRD1	-0.062080
TOR1B	0.061227
SLIRP	0.060510
GLRX	0.059795
YARS	-0.059770
SSR2	-0.059473
CHST6	0.058436
CDC20	0.058222
OLFML3	-0.058153
ACAT2	-0.058026
NME4	-0.056971
HINT1	-0.055862
PFN2	-0.055364
ZNF280A	0.055310
GLO1	-0.055010
DHCR24	-0.054778
ARMCX6	0.054439
PDE1A	-0.053514
PTPRK	-0.053397
BTG1	0.053326
ATF4	-0.053187
PCNA	-0.053120
MSMO1	-0.052479
TRMT5	-0.052401
CKS1B	0.052030
ANXA2	0.051682
DHX15	-0.051677
TUBB2A	0.051464
TMEM97	-0.050611
ARHGAP29	0.050594
PCBP1	-0.050490
TPM1	0.050154
RPL3	-0.049789
FUCA1	0.049680
VIM	0.049638
TRIB1	0.048908
GINS1	-0.048712
EEF2	0.048649
KARS	0.048591
GMPS	-0.048021
XPOT	-0.047850
PTGES3	-0.047635
PSMD1	-0.047552
TUBA1A	-0.047524
BIRC2	0.047463
PSAT1	-0.047348
COX6A1	0.047102
RPL28	0.047091
PPIB	-0.046956
AURKA	0.046800
RND3	0.046791
PPA2	-0.046746
IDI1	-0.046454
CKB	0.046175
HIST1H4C	-0.046154
UBE2C	0.046009
LBH	0.045884
VCP	-0.045840
GMNN	-0.045837
KRT8	0.045705
LSM1	0.045629
COX6B1	0.045606
OAZ1	-0.045011
XRCC5	-0.044620
MRPL3	-0.044610
HCLS1	0.044534
PSMC3	-0.044350
CBS	-0.044228
SDCBP	0.044208
TMSB15A	-0.044088
CKS2	0.044015
PHGDH	-0.043410
PSMA5	-0.043308
CDIPT	0.043128
RPS18	0.043092
RPS27	0.042860
FABP5	0.042848
SCD	-0.042548
IDH1	-0.042222
PEA15	0.042114
ARPC5L	0.041897
TAGLN2	0.041856
PTTG1	0.041514
LASP1	0.041428
MTCH1	0.041406
IFRD1	0.041353
BLCAP	0.041183
HPRT1	-0.041085
TMA7	0.040955
CD63	0.040942
TUBB2B	0.040615
PODXL	0.040320
TMEM106C	-0.040033
SARS	-0.039872
TRIB3	-0.039749
FBN2	-0.039599
SHMT2	-0.039567
TIMM8B	0.039422
PBK	-0.039295
H2AFY2	-0.039225
MDK	0.039122
NR0B1	0.039003
STRA13	-0.038988
NPY1R	-0.038596
KIAA0907	0.038300
PPP1R15A	0.038263
HMGN2	-0.038182
UBE2E3	-0.038182
AP2S1	-0.038171
TBCB	-0.038094
DDIT3	0.037908
TFPI2	0.037905
EFNB2	0.037851
CARHSP1	-0.037791
PTMA	-0.037489
CLTC	-0.037311
MARS	-0.037001
SF3B5	0.036999
IRAK1BP1	-0.036898
ATP1B3	0.036727
DPM1	0.036446
KIAA0101	-0.036200
RPL6	0.036058
NHP2	-0.035927
ADI1	0.035890
SEC61B	0.035846
PHLDA2	0.035717
EIF3C	-0.035099
UBA1	0.034956
CEBPB	0.034929
FADS1	-0.034895
ACTG1	-0.034851
GNB1	-0.034806
LMNB1	-0.034764
TOP2A	0.034685
SLC25A6	-0.034672
HNRNPR	-0.034615
ITGB3BP	-0.034555
GINS2	-0.034536
KIF20A	0.034304
ROBO1	-0.034148
UQCR11	0.034130
HNRNPA2B1	-0.034033
EIF5	0.033842
CENPU	-0.033831
RTN4	-0.033829
PIR	-0.033801
CCNG1	-0.033731
GNPAT	-0.033617
AKR1A1	-0.033555
HAX1	-0.033528
DHCR7	-0.033519
TUBB6	0.033460
DCLRE1A	-0.033403
STX3	0.033314
FADS2	-0.033312
ITM2A	0.033280
IER3	0.033259
PPP1R14B	-0.033139
SRSF2	-0.033050
BASP1	-0.033021
FNBP1	-0.033019
TNFAIP6	0.032938
IMPDH2	0.032929
CDC37	0.032872
MAP1B	-0.032782
HIST2H2AA3	0.032710
RPA3	-0.032656
SRSF3	-0.032619
NCOA4	0.032564
IER5	0.032520
PLS3	0.032468
TPM2	0.032393
SLC24A3	-0.032345
CXADR	0.032288
FLNC	0.032240
CTSL	0.032217
IER2	-0.032180
CAPNS1	-0.031917
ACTN1	0.031828
RBBP8	-0.031781
POLR2I	-0.031756
CAPRIN1	-0.031747
HOOK1	-0.031710
B2M	0.031642
PRNP	0.031624
PSMA4	-0.031619
RPS26	0.031528
IGFBP4	0.031484
PARK7	0.031480
RPL9	0.031458
IFITM3	0.031127
ATP1A1	0.031113
MRPL17	-0.031023
PABPC1	0.030947
SQLE	-0.030944
BZW2	0.030875
COCH	-0.030799
LRRC47	0.030798
SNX3	-0.030759
EMG1	-0.030703
THY1	0.030411
CFL1	0.030378
CCNB1IP1	0.030373
UBA52	0.030242
IMMT	-0.030172
EPHB3	0.030108
FAM171A1	-0.029876
MAPK6	-0.029862
PNP	0.029809
SNRPA1	0.029785
IRS2	-0.029540
HSPA1A	-0.029469
HAT1	-0.029392
MATR3	-0.029302
ATP6V1G1	0.029301
FAM53C	0.029153
SSRP1	-0.029120
APEX1	-0.029104
APLP2	0.029092
SLC35F2	0.029041
CDK1	0.028869
MIF	-0.028864
HIRA	-0.028811
MMP3	0.028809
HMGN3	-0.028796
FADS3	0.028743
GLG1	-0.028736
BAG6	-0.028715
NAE1	-0.028658
MAFB	0.028614
PGD	-0.028513
ARPC2	0.028513
EPB41L2	-0.028418
PSME2	0.028380
GLA	0.028266
TALDO1	-0.028198
EPRS	-0.028128
AHCY	-0.028124
RBM39	-0.028076
MLH1	-0.028074
ATP5L	0.028030
GOLGA7	0.028008
POLR2G	-0.027969
CCT5	-0.027966
SLC5A3	0.027844
RAB13	0.027817
MORF4L1	-0.027815
USP11	0.027810
RPS16	-0.027732
LPCAT1	-0.027698
HSD17B4	-0.027664
HSPD1	-0.027587
RPL27	0.027543
EIF3D	0.027480
PLVAP	-0.027368
SAE1	-0.027367
HLA-A	0.027274
NUP107	0.027204
TCEA1	-0.027158
RPLP1	0.027133
MYL6	0.027048
PLA2G4A	-0.026969
RGS5	0.026938
SRI	-0.026888
NET1	0.026882
KPNA2	0.026864
CSRP1	-0.026832
MRPL39	-0.026796
CLU	0.026764
PHIP	-0.026743
RIN2	0.026722
EIF2B2	0.026709
MSX1	0.026679
SMG1P2	0.026666
PSMA7	-0.026622
PHB2	-0.026571
BMPR1A	-0.026554
RPL7A	0.026513
H1FX	-0.026492
ATP5E	0.026459
PSMC1	-0.026423
PLTP	0.026345
JAG1	0.026281
DLD	-0.026278
VPS35	0.026247
DNAJB6	0.026237
SOD1	-0.026195
LSG1	0.026180
RRM1	-0.026156
POLA1	-0.026090
PARP2	-0.026089
ALDOA	0.026072
RPL41	-0.025987
UQCRC1	0.025938
NPC2	0.025785
GOT1	-0.025731
RAE1	0.025703
MORF4L2	0.025698
ARMCX3	0.025692
GSTA4	-0.025577
POLDIP2	0.025554
GTPBP4	0.025502
PSMC4	-0.025475
SDC4	0.025410
MAN2A1	-0.025371
PTX3	0.025364
RPS29	0.025316
SRP14	0.025302
SHC1	0.025216
DCP2	-0.025194
HSD17B7	-0.025194
MAP1LC3B	0.025141
TOMM7	-0.025033
CST3	0.025032
CD24	0.025031
RBBP7	-0.024914
GADD45A	0.024868
LRPPRC	0.024868
MARCKS	-0.024867
TARS	-0.024857
EIF2B3	-0.024853
FAM21A	0.024830
NDUFC1	0.024781
VOPP1	0.024768
PTPLA	0.024747
PLK2	0.024743
NR2F2	-0.024703
SERPINH1	0.024683
MRPL49	-0.024679
HMGCR	-0.024648
ZFAND5	0.024494
CCT7	0.024446
PSMD7	-0.024436
SNAP23	0.024418
UROD	0.024411
ATP6V1D	0.024329
NSMCE4A	-0.024326
DAPK1	-0.024272
SH2B3	-0.024239
UPF3B	0.024236
TUFT1	0.024205
CLNS1A	0.024186
HADHB	0.024089
TPT1	0.024072
DDX5	0.024053
RNASET2	0.023935
CYP51A1	-0.023894
TAX1BP3	0.023785
HIST1H2BH	0.023715
FAU	0.023678
PSAP	0.023592
SOX11	-0.023540
FNTA	0.023524
PSMB1	-0.023462
RPL4	0.023411
TMEM59	0.023404
PACSIN2	0.023370
NDUFB5	0.023362
RPS9	0.023329
ATPIF1	0.023309
TUBA1C	0.023258
SSR4	0.023252
CHCHD3	-0.023251
PDIA3	-0.023242
NDUFS2	-0.023241
UFC1	-0.023183
CRY1	0.023130
WARS	-0.023097
RPSA	0.023083
RRAGC	0.023061
BTBD1	-0.023050
TRA2B	-0.023016
HEATR1	-0.022995
HMMR	0.022977
SNRNP25	-0.022939
NCKAP1	-0.022814
PABPC3	0.022813
NPY	0.022774
TYRP1	0.022722
GBAS	-0.022715
DPYSL2	-0.022707
ESD	-0.022697
DPF2	0.022678
EMC7	0.022637
HSPA9	-0.022635
RBM15	0.022586
PCCB	-0.022579
C20orf24	0.022572
HSD17B12	-0.022541
DSP	0.022532
RAB31	0.022459
HDAC1	0.022433
PRIM1	-0.022356
MXRA7	0.022349
NPM3	-0.022343
UCHL3	-0.022328
AIMP2	0.022306
USP14	-0.022303
FASN	-0.022292
TCEB2	0.022290
MARCKSL1	0.022278
METAP1	-0.022246
TXNDC5	-0.022205
SARAF	0.022191
NONO	-0.022188
HMGB1	-0.022128
FAF1	-0.022079
NOC3L	0.022018
MRPL12	-0.021957
DENR	0.021947
MCM6	-0.021894
GDI2	-0.021859
SYF2	0.021824
COX7B	0.021774
CKAP4	-0.021739
CSNK2B	0.021739
ATP5B	0.021730
CTCF	-0.021700
POGK	-0.021672
NUTF2	-0.021665
TWIST1	0.021663
DDX21	0.021663
LDHA	-0.021620
NOSIP	0.021607
SEC61G	-0.021589
BOP1	-0.021589
MAFF	0.021549
SHFM1	0.021544
APIP	-0.021502
CDH11	-0.021499
LY96	0.021438
EBNA1BP2	0.021410
MRPS35	-0.021406
SMAGP	0.021401
TUG1	0.021323
FTH1P5	0.021313
RTN3	-0.021304
HIST1H2BE	0.021295
CTGF	0.021248
WDR26	0.021213
BAMBI	0.021192
UBE2Q1	0.021180
LSM2	-0.021118
CSE1L	-0.021084
TXNRD1	-0.021057
CLTA	0.021051
SOX9	0.021047
CARM1	-0.021027
C11orf48	0.020959
FSTL1	0.020948
MDH1	0.020935
AKR1C3	-0.020915
WRB	-0.020913
F8A1	-0.020892
DUT	-0.020890
ZDHHC11	0.020883
GLRX5	0.020833
C14orf2	0.020830
HJURP	0.020827
MSN	-0.020745
CYC1	-0.020726
RPL10A	-0.020718
CORO1C	0.020704
P4HB	-0.020662
PLK1	0.020619
ITFG1	-0.020615
MMD	-0.020589
TRIB2	0.020580
IDH3B	0.020515
ASCC3	-0.020468
ISCU	0.020457
ATP5J2	0.020433