!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Cadmium dichloride
!smiles	Cl[Cd]Cl
!pubchem_cid	24947
!cell_type	H4-II-E-C3 LIVER-derived cell line -  0.2 uM
!organism	rat
!end_metadata
APOA1	0.071507
SLC17A3	0.062083
CD36	0.057014
PLA2G1B	0.052016
TGFBI	0.049417
SLC2A2	0.048725
ALDH1A1	0.048589
GDA	0.047785
CYP39A1	-0.047702
LYST	0.046857
SULT1C2	0.046230
C3	0.045175
ATF3	0.044398
MEX3B	0.042465
CDKN1B	-0.041841
GDE1	0.041572
ALDH3A1	0.041397
AADAC	0.041310
CITED1	0.040045
AOX1	0.039835
ATF5	-0.038893
EMP1	0.038631
AHNAK	0.038603
LRP5	-0.037961
USP29	-0.037497
ACKR4	-0.037226
FAM180A	-0.037050
KCTD15	0.036964
KIF20B	-0.036659
CTSE	0.036333
HSPA4	-0.036095
P2RY2	0.035675
GNAQ	-0.035533
HEBP1	0.035302
E2F8	-0.034264
SH3TC1	-0.034215
CCNA2	-0.034198
CUTC	0.034034
ABCC2	0.033362
MIS18A	-0.033287
BIRC5	-0.032762
ISLR	-0.032702
FOXQ1	0.032629
CLOCK	0.032516
CDKN3	-0.032511
GRHL1	0.032212
CXCL2	0.032210
ACSM5	0.032175
GADD45G	0.032144
CDYL2	0.032127
IDNK	0.032032
UHRF1BP1	0.031512
AMPD3	0.031291
APOC2	0.031170
PRPF19	-0.030919
AXIN2	-0.030850
SHPK	0.030788
TCF19	-0.030591
ZNF778	0.030367
UMOD	-0.030340
ALDH1L1	0.030150
ALDH3B1	0.030142
KIF18A	-0.029649
MXD3	-0.029628
CSAD	0.029590
UBE2T	-0.029450
PCSK6	0.029375
ZC3H6	0.029320
SLC29A1	0.029305
GSTA3	0.029238
F12	0.029220
ITIH4	0.029041
MIS12	-0.029007
FUT9	0.028992
DHX9	-0.028924
EML2	-0.028768
RPS6KA5	-0.028688
MMP15	0.028628
SYT11	-0.028537
TBR1	-0.028454
SLC7A11	0.028422
GJA4	-0.028381
THNSL1	0.028311
GADD45A	0.028309
FAM83D	-0.028229
MMP19	-0.028220
TIMELESS	-0.028193
AGRN	0.028146
KIF5B	-0.028111
FAH	0.027977
SGOL2	-0.027967
SLC38A9	0.027862
TMEM150A	0.027809
HMGB2	-0.027727
AGXT2	0.027721
CXCR2	-0.027601
TNFRSF21	0.027594
ITGBL1	0.027509
NDC80	-0.027205
AURKB	-0.027193
INO80B	-0.027189
SMC2	-0.027180
PRSS36	0.027158
ZFP37	-0.027133
ID1	0.027128
SETBP1	0.027092
SPATC1	0.026691
UHRF1	-0.026689
OSGIN1	0.026620
PDGFA	-0.026590
SPP2	0.026553
CXXC4	-0.026516
STARD8	-0.026496
TOP2A	-0.026439
CCL17	-0.026410
SAMD8	-0.026281
CDCA2	-0.026140
P2RX6	0.026123
ADIPOR2	-0.026093
NEU2	-0.026080
AQP6	-0.025927
MANSC1	-0.025879
KMO	0.025815
HJURP	-0.025779
TIE1	-0.025777
XKR5	-0.025765
RAPGEF1	-0.025756
MSRA	-0.025678
SCN11A	0.025660
MYC	0.025652
TLE2	0.025607
PPY	-0.025547
CCDC61	0.025525
PLA2R1	-0.025520
SLC12A6	0.025487
CDO1	-0.025394
SLC17A1	0.025358
EGR1	0.025332
BAK1	-0.025206
APOB	0.025158
MACROD1	0.025137
ACER1	0.025126
SPRR1A	-0.025092
TRIM62	-0.025090
SMARCA1	0.024960
KCNK4	-0.024949
CASP4	0.024940
GBP6	0.024931
RUNX1	0.024914
PFKP	0.024914
HNRNPUL1	-0.024910
SPSB4	-0.024839
FAM129A	-0.024738
SEP15	-0.024732
AMFR	-0.024700
ASCL3	-0.024693
BPIFB2	-0.024671
IDUA	0.024588
JAG1	0.024572
FAM216B	-0.024529
IDH1	0.024507
SPINK4	-0.024500
PRC1	-0.024470
RHOH	0.024418
MAPK12	-0.024413
ADIPOQ	-0.024392
CYP4B1	0.024381
INF2	0.024373
BUB1	-0.024371
RIOK3	0.024362
PARM1	-0.024350
SP2	-0.024331
CNDP1	0.024270
BAMBI	0.024210
SLC7A6	0.024188
AQP11	0.024124
TXNRD1	0.024040
GNG7	-0.023989
CENPU	-0.023988
RAD51AP1	-0.023968
ME1	0.023949
ANKRD37	-0.023949
DLX1	0.023940
MMS22L	-0.023821
CHAC1	-0.023798
AGPS	0.023677
SLC48A1	0.023631
MAPK6	0.023579
TACC2	0.023546
ISOC1	0.023484
PTH2R	-0.023467
CHRNA5	-0.023410
SLC44A4	-0.023402
CHRNA2	-0.023385
UBALD2	0.023367
MYO9A	0.023338
SIAH2	0.023337
PPFIA2	0.023332
TIFA	0.023313
HYKK	0.023291
AKR1B10	0.023282
FAM129B	0.023242
ZC3H12A	0.023237
FAM167A	-0.023176
SAPCD2	-0.023165
NFATC1	0.023141
FUOM	0.023141
DBN1	0.023105
RELL2	0.023103
PLK4	-0.023083
ZNF775	0.023071
ERCC6L	-0.023065
MMAA	0.023044
ENTPD5	0.023037
PCDH7	-0.023033
KNSTRN	-0.023030
SPATA5	0.023029
FABP2	-0.023015
HMOX1	0.023006
SLC38A4	0.022978
ACYP2	0.022962
CLCF1	0.022960
HAS2	-0.022929
MKI67	-0.022928
ARL2	0.022905
MEP1A	-0.022839
UBE2C	-0.022834
ONECUT2	0.022831
RGS7	-0.022820
KIF23	-0.022815
MGARP	-0.022805
FCER1A	0.022794
PRSS22	-0.022792
RTN4	-0.022715
PSTPIP1	-0.022661
HDDC3	-0.022644
LGALS3BP	0.022638
REEP6	0.022610
ARHGAP11A	-0.022561
COMT	0.022546
KL	-0.022537
ACAD10	0.022524
CA6	0.022520
ZNF367	-0.022515
NAPB	0.022515
GJB2	-0.022461
SGCG	-0.022461
UGDH	0.022437
SIL1	0.022429
ZNF365	-0.022395
CRYM	-0.022365
RPRM	-0.022345
L3MBTL2	0.022345
HEXB	0.022321
SLC41A2	0.022289
CREB3L2	-0.022253
VTN	0.022214
H6PD	0.022210
IL2RA	-0.022202
FOXRED1	0.022164
BAIAP2	0.022144
TH	-0.022140
TRPV4	-0.022123
GOT1L1	-0.022113
ZFAND2A	0.022108
CHRM1	-0.022104
IGSF21	-0.022052
ERCC6	0.022036
FAAH	0.022027
PTTG1	-0.022000
DLGAP5	-0.021998
NHEJ1	0.021938
CLCNKB	-0.021937
NUBPL	-0.021934
XK	0.021844
NACC1	-0.021837
NR3C1	0.021813
ARMCX5	0.021782
MICALCL	0.021764
ST3GAL6	0.021760
PARPBP	-0.021757
ZNF585A	0.021754
SAMD10	0.021754
PSD	-0.021753
IRAK2	0.021724
ABCC6	0.021720
MCM5	-0.021665
CYP2S1	-0.021653
CCDC107	0.021652
ABCA7	0.021636
S100A5	0.021617
DNASE1	-0.021614
ECT2	-0.021614
PGLYRP1	-0.021600
GLT8D2	-0.021588
TJP3	0.021521
MAZ	-0.021506
BTG3	0.021492
PTPRN2	-0.021459
DSN1	-0.021458
RAP2A	-0.021456
FDXR	-0.021445
NAGLU	0.021443
LY86	-0.021440
ABCC4	0.021419
ATRNL1	-0.021387
CDCA3	-0.021384
DNM1L	0.021328
MAX	-0.021312
PLEKHH1	0.021272
ARHGAP24	-0.021252
SLC26A8	0.021236
PRKG2	-0.021232
GZMK	-0.021227
IL1R2	0.021225
MBIP	-0.021206
PPAP2B	-0.021204
DLG2	-0.021180
NIPSNAP1	0.021179
IQGAP3	-0.021113
ATN1	-0.021081
ZHX2	-0.021074
GTF2E1	0.021064
LAP3	-0.021064
PTPN3	0.021054
LRRN3	-0.021038
SLC4A2	-0.021025
PCDH19	-0.020989
CD37	-0.020971
POLR2L	-0.020959
DCN	0.020949
CSPP1	0.020947
PTGR1	0.020941
KIF2C	-0.020937
GPR37L1	-0.020902
TMEM179	-0.020883
TMEM70	-0.020882
MAFF	0.020879
KPRP	-0.020871
ZSWIM6	0.020869
PWWP2B	-0.020843
PRLH	0.020826
TMEM140	0.020825
NUFIP2	-0.020811
FUK	0.020789
KXD1	0.020789
MAFB	0.020788
GPR162	-0.020777
CA7	-0.020765
FAHD2B	0.020762
TINAG	0.020748
SERTM1	-0.020747
AFP	0.020743
TRIM14	0.020739
TSTD2	-0.020725
LGALS3	0.020722
VWF	-0.020710
PRMT9	0.020694
TTR	0.020675
TGFBR1	0.020674
TPD52L1	-0.020669
STAB2	-0.020666
CGREF1	0.020659
AXL	-0.020651
BBS2	0.020651
FAM151A	-0.020645
CDH2	-0.020633
YPEL5	0.020594
PDZK1	0.020592
C8G	0.020531
NKRF	0.020508
SYN1	-0.020474
IFNK	0.020460
PDE6H	-0.020421
CENPQ	-0.020416
ITPR3	0.020391
ALDH1B1	-0.020377
TNIK	0.020355
GTPBP2	0.020348
NUP133	0.020333
TAF8	0.020317
CACNA1S	0.020309
TMEM130	-0.020308
DYNC2H1	0.020298
HSD3B1	-0.020294
CD163	-0.020274
CD14	0.020270
GCH1	0.020264
TMEM231	0.020243
CENPA	-0.020201
KLF5	0.020193
ZFYVE9	-0.020184
AHCYL1	0.020180
ACAD11	0.020156
HDC	-0.020139
KCNH4	-0.020128
OXLD1	0.020125
TULP2	-0.020117
SELENBP1	0.020082
RP1	0.020021
MAP3K8	0.020018
RIN1	-0.020004
EGLN3	-0.019989
SYT16	0.019986
PDE12	0.019984
TXLNA	-0.019976
ACSS2	0.019964
NOTCH3	-0.019949
LYSMD2	0.019947
DDAH1	0.019932
TM7SF2	0.019905
POLE2	-0.019895
MYL2	-0.019887
FAM210A	0.019884
LTB	0.019829
FKBP9	-0.019799
MIA3	-0.019783
CHRNE	0.019761
PUS10	0.019746
FBXL17	0.019725
GPD1	0.019723
LECT2	-0.019720
LIPC	0.019713
FXYD7	-0.019688
TTC9B	-0.019678
FOXJ2	-0.019655
YTHDF3	0.019620
NHLRC2	0.019619
MND1	-0.019608
GPT2	-0.019595
DDX58	0.019575
NEU3	-0.019572
RNF122	0.019571
SLC6A7	-0.019552
SNRPD3	-0.019538
YPEL4	0.019533
TRIB3	0.019523
HSD17B14	-0.019520
SASS6	-0.019507
ANGPTL3	-0.019503
H2AFX	-0.019489
GIF	-0.019485
AGO2	-0.019470
USP27X	0.019460
NOP9	0.019460
GSS	0.019456
RHOBTB1	0.019441
ZDHHC20	-0.019433
CKS2	-0.019401
CHTF18	-0.019398
PARP9	0.019392
CPB1	-0.019391
JDP2	-0.019380
COQ10A	0.019366
TMEM106A	0.019351
TINAGL1	0.019345
FBXO46	-0.019339
TEK	-0.019327
VPS54	-0.019320
TBC1D31	-0.019319
FAM178A	-0.019301
H2AFJ	0.019294
ANKRD11	-0.019293
CCL4	-0.019286
LSM12	-0.019271
ANKEF1	-0.019268
HELT	-0.019266
SLC27A2	-0.019255
FGL1	0.019244
ZFP90	0.019232
VAV3	0.019217
WNT4	0.019214
COL9A3	-0.019204
ESR1	-0.019202
PLEKHG2	0.019194
PKM	-0.019178
HTATIP2	0.019150
SMIM3	0.019146
CTGF	0.019134
SCRG1	-0.019122
TBC1D17	0.019116
TRIM46	-0.019114
C9	-0.019098
TAS2R13	-0.019095
SEPT4	0.019090
PVR	0.019068
G2E3	0.019064
NR3C2	0.019057
IFT122	0.019056
AQP7	-0.019023
TBC1D10C	0.019019
SHC4	0.019017
ARF5	-0.018980
ST6GALNAC3	-0.018975
MTAP	0.018967
STEAP2	-0.018941
RACGAP1	-0.018921
KAZALD1	-0.018921
NUDT13	-0.018918
TRAPPC6A	0.018911