!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	MCF-7 cells
!organism	human
!end_metadata
LINC00341	0.128540
MN1	0.128239
P2RY2	0.126685
FST	0.115744
FOS	0.112620
PLAC1	0.095835
DKK1	-0.095209
RNF43	-0.093230
EPB41L3	0.093019
RASGRP1	0.092583
KCNK5	0.087150
HOXC6	0.084738
CYP26A1	0.084074
PLEKHO2	0.078816
PGR	0.078407
WNT5B	0.077680
PDZK1	0.076648
C8orf4	-0.076376
SERPINB9	0.076140
SGK1	0.074817
HOXC5	0.074726
MYBL1	0.073737
ID3	-0.072694
CBFA2T3	0.072082
ARID5B	-0.072068
FOXC1	0.071598
HOXC4	0.070401
EGR3	0.068099
WNT4	0.068012
CCNG2	-0.067086
TIPARP	0.066312
STC2	0.065537
PDP1	-0.064914
BCL11B	0.064461
VWF	0.063650
IL17RB	0.061603
KIAA0226L	0.061059
FADS1	0.060595
SAG	0.060368
SIAH2	0.059851
ID1	-0.059234
CLDN1	-0.058278
FCGR2B	0.057856
GNAI1	-0.057724
LRRC15	0.057489
TMPRSS3	0.057214
SEC14L2	0.057043
FZD7	0.056515
CREB5	-0.055800
FAM13A	-0.054650
REEP1	0.054190
ADRB1	0.053656
EDN2	0.053403
KITLG	-0.053397
EFNA1	-0.053102
PRSS23	0.052591
BIRC3	0.052262
HSD11B2	0.052013
GCNT1	-0.051953
GATA3	-0.051900
TNFRSF11B	-0.051597
CAV1	0.051484
SEMA3G	0.050610
TGFB2	-0.050442
SESN1	-0.050386
NCF2	0.050352
NRIP1	0.050341
RGS16	0.049835
FAM63A	0.049547
BCL6	0.049527
ANKRD2	0.049511
MEIS1	0.049503
ENC1	-0.049326
MYC	0.049300
VEGFC	-0.049080
ABTB2	0.049070
CHST8	0.048762
TRIM36	-0.048643
C14orf132	0.047707
ARL4A	-0.047575
SIK1	0.047368
NR5A2	0.046952
TSKU	0.046739
ASB13	0.046556
KLF4	0.046430
PALMD	-0.046368
ABCG2	0.046238
HEG1	0.046238
RAB31	0.046210
SH3TC1	0.045859
SLC22A5	0.045840
OTUB2	0.045253
TRIB1	-0.044843
DUSP10	-0.044747
WISP2	0.044711
PIM1	0.044383
TFF2	0.044264
PMAIP1	0.044106
SNAI2	0.044027
DDIT4	-0.043973
CYR61	0.043751
GNMT	-0.042960
RCL1	0.042958
BLNK	-0.042932
GADD45B	0.042901
RWDD2A	-0.042851
GRAMD3	-0.042770
IRX5	-0.042665
RARA	0.042610
HHEX	-0.042473
PITX1	0.042325
CASP7	0.042218
AMIGO2	-0.041875
GADD45G	0.041842
PLA2G16	0.041658
GAB2	0.041620
HILPDA	-0.041539
TSPAN5	0.041500
CCDC88C	0.041158
SSTR2	0.041124
TUBA3D	0.041120
UPF1	0.040832
RGCC	-0.040522
HEY1	-0.040400
OLFML3	0.040246
TBX2	0.039876
HSPB8	0.039597
KLF3	-0.039542
INTS6	-0.039489
HIVEP1	-0.039469
CA12	0.039050
IRS2	0.038997
SMOX	0.038940
MAMLD1	0.038882
SLC16A6	0.038882
TUBBP5	0.038593
PFKFB3	0.038538
SLK	0.038498
CRISPLD2	0.038288
PPP1R3C	-0.037869
SCG5	-0.037792
MTUS2	0.037492
PTPRH	0.037375
C10orf2	0.037243
DSE	-0.037242
TWF2	0.037227
MAP6D1	0.037061
WFS1	0.037034
RAB20	-0.036963
PXDC1	0.036793
HOXC10	0.036658
HIVEP2	-0.036163
OVGP1	0.036143
WWC1	0.035802
ACVR1	-0.035779
BMP4	-0.035463
NEDD9	-0.035435
PTPRE	0.035333
RASL11B	-0.035101
CXCL12	0.035084
TBKBP1	0.035061
ZNF552	0.034872
MMD	-0.034839
MICB	0.034788
CDC42EP1	0.034689
SBNO2	0.034664
MCF2L-AS1	0.034466
LMO4	-0.034278
SYBU	0.033949
PLAT	0.033859
INSM1	0.033830
MYO1E	-0.033703
ITGB6	-0.033631
GEM	0.033616
CCND1	0.033470
NEDD4	-0.033439
C3orf52	-0.033406
PLS1	-0.033359
MAF	0.033081
FJX1	0.032985
HK2	0.032754
RNF144A	0.032701
JARID2	0.032626
DDX58	-0.032577
KLF5	-0.032439
PTGES	0.032335
ANXA9	0.032331
LRIG1	0.032270
EPB41L4A-AS2	-0.032218
AKAP1	0.031997
TDRD1	0.031765
PPIF	0.031754
C6orf211	-0.031744
PIK3IP1	-0.031543
CSRNP2	-0.031476
TCF7L1	0.031302
OSTF1	0.031274
GRB14	-0.031216
SEMA4C	-0.030981
AREG	0.030973
SIX1	-0.030946
IGFBP4	0.030804
PPRC1	0.030793
ID2	-0.030653
CYP2R1	0.030442
BCOR	-0.030429
TUBA3C	0.030319
MAFF	0.030302
DHRS2	0.030221
NXT1	0.030154
CDKN1B	-0.030154
PPFIA4	0.030123
LRP4	0.030089
ZBED8	-0.030069
SOX4	-0.030052
FKBP14	0.029914
FHL2	0.029802
ZNF184	-0.029723
IL10RA	0.029710
HCP5	-0.029687
FAM69A	-0.029610
GAREM	-0.029554
SSFA2	-0.029535
KAZN	0.029516
B3GNT3	0.029394
LPHN2	-0.029340
C4orf19	0.029235
EGLN3	-0.029166
SNX24	0.029140
JAG1	-0.029048
LMO3	-0.029046
TTC9	-0.029037
SACS	0.028922
SLC7A5	0.028893
SPRY1	-0.028887
AEN	0.028820
CXCR4	-0.028744
PIK3R3	-0.028712
SNHG20	0.028705
TBX3	-0.028653
RET	0.028544
IL24	0.028536
FRY	-0.028508
SOCS1	0.028455
SPSB1	0.028395
USP36	0.028372
WEE1	-0.028308
SLC25A24	0.028258
CHSY1	0.028227
URB2	0.028221
TAZ	0.028216
SLC30A1	0.028200
ANG	0.028148
ARHGAP32	-0.028146
PPP1R3D	-0.028123
IRS1	-0.028113
NKX3-2	0.028072
TLN2	0.028027
CLN8	0.027993
SLC26A2	0.027978
EFNA4	-0.027961
SERTAD3	-0.027939
DLX2	-0.027890
OLFML2A	0.027868
SLA	0.027864
ELOVL2	0.027744
INPP5A	0.027714
TNS1	0.027647
MKNK1	0.027595
SOX9	-0.027580
SLC29A3	0.027543
HMOX1	-0.027488
AVPI1	-0.027411
KIAA0922	-0.027388
CALHM2	-0.027339
ARMCX6	0.027272
FZD2	-0.027239
REL	-0.027228
IRGQ	0.027011
MYLK	0.026963
ZKSCAN4	-0.026910
TLR2	-0.026802
USP2	-0.026757
GREB1	0.026746
CEMIP	0.026704
CHD1	-0.026682
MTCL1	-0.026641
KDM4B	0.026617
SMAD7	0.026601
ST3GAL5	0.026555
KCNJ3	-0.026530
EXO1	-0.026526
SLC25A28	0.026524
PARD6B	0.026377
BATF	0.026250
ACVR2A	-0.026225
KDM6A	-0.026191
ELF1	0.026138
ACTG2	-0.026013
WWTR1	-0.025993
HOXC11	0.025973
JADE1	0.025968
TNFAIP8	-0.025954
FZD4	-0.025850
KCNMB1	-0.025846
PLEKHF2	-0.025839
MAP3K1	0.025838
YEATS2	-0.025825
RHOBTB3	0.025812
TRIB3	-0.025742
SH2D4A	-0.025612
DAPK2	0.025612
RAB9A	-0.025550
VLDLR	0.025495
PNRC1	-0.025488
FAIM3	0.025466
INHBB	0.025370
S100PBP	-0.025355
SCYL3	-0.025221
OPN3	0.025195
CYP1B1	0.025126
FGD6	0.025022
FLVCR2	0.024815
MED23	-0.024777
RNASE4	0.024771
TGIF1	-0.024747
ARID4A	0.024738
RAB11FIP1	0.024680
LOC100272216	-0.024635
FAM134B	0.024614
LYRM1	0.024586
RAB30	0.024582
NUPR1	-0.024563
FOXJ2	-0.024448
FRAT1	-0.024438
BTG2	-0.024422
MREG	0.024401
DOCK2	-0.024316
HOMER2	0.024263
CARD14	-0.024204
ANGPTL4	-0.024120
VEGFA	0.024086
SLC36A1	-0.024015
SLC7A6	0.023868
CXADR	-0.023858
TRIB2	-0.023851
FAM216A	0.023787
SLC6A14	-0.023763
IGFBP3	0.023706
SH2B3	0.023703
SLC10A3	0.023671
DIO1	0.023634
GUSBP3	-0.023552
SHB	0.023369
RAD54B	-0.023341
TOB2	-0.023284
SWAP70	-0.023210
GEMIN4	0.023138
AMMECR1	0.023124
DDX10	0.023106
FBXO34	0.023103
WDR47	-0.023079
MISP	-0.023069
RGL1	-0.022959
DHCR7	0.022952
POLR3B	-0.022951
SOX3	0.022931
COA7	0.022900
RSRP1	-0.022802
HCRP1	-0.022790
SERPINE2	0.022779
MED24	0.022768
TGIF2	0.022658
PPARGC1A	-0.022645
C21orf91	-0.022628
LRP5L	0.022575
CCDC86	0.022561
TRIM45	-0.022520
IL19	0.022515
NIP7	0.022500
DHRS3	0.022494
ARHGEF10L	0.022488
PAWR	-0.022466
RNF38	-0.022416
CXCL8	0.022398
ARHGAP12	-0.022372
AHR	-0.022306
XYLT1	0.022278
CALD1	-0.022156
KCNF1	0.022113
OSTM1	-0.022105
BBC3	-0.022088
CUEDC1	0.022074
NMRK1	0.022047
TRIM38	-0.022038
LIMK2	-0.022015
TRPS1	-0.021998
GFOD1	0.021990
YAP1	-0.021839
ROCK2	-0.021782
MARCH3	0.021729
ZNF606	-0.021712
KLF9	0.021690
KDM7A	0.021643
FKBP4	0.021636
CLEC2D	-0.021622
NR2F1	-0.021611
FAS	-0.021608
NFATC1	0.021579
TIMP3	-0.021537
FERMT2	-0.021530
PIK3CA	-0.021523
E2F6	0.021513
IL10RB	-0.021508
ZCCHC24	-0.021496
ATXN1	-0.021448
PPAN	0.021413
NKX2-2	-0.021403
POLR1C	0.021400
FAM102A	0.021400
IFNGR1	-0.021386
CXCL3	-0.021164
CRKL	0.021156
STAM	0.021147
COLEC12	0.021123
GBP1	-0.021046
SOX2	-0.021039
CHST1	0.020991
BMI1	-0.020990
ATP2B1	-0.020988
POP1	0.020963
ZNF652	-0.020926
ZMIZ1	0.020911
LPIN2	-0.020834
EFNB2	0.020801
A4GALT	0.020749
ODAM	-0.020740
CDK17	-0.020667
HOXC8	0.020579
C12orf5	-0.020532
GNA14	0.020513
VPS54	-0.020511
RPS6KA2	0.020503
ZNF155	0.020480
MEIS3P1	0.020466
GPR126	-0.020444
DDX21	0.020366
MID1	-0.020358
FFAR2	-0.020335
TMEM104	0.020312
NAV2	0.020205
IER2	-0.020186
LMOD1	-0.020185
EHD1	0.020134
ZNF14	-0.020087
ACP6	0.020079
NXPE3	0.020053
TRAF5	-0.020052
OR7E14P	0.020035
PCYOX1	0.020022
XK	-0.019996
ZC3H12A	-0.019988
ZNF551	0.019985
SATB1	-0.019923
LIN37	-0.019881
TLE3	0.019832
MAX	0.019810
RNF39	-0.019779
ZBED4	0.019765
GAS1	-0.019688
CEBPD	-0.019660
MPP5	-0.019649
ABHD10	-0.019619
CHST11	0.019545
JUND	0.019529
ZNF185	0.019479
SIDT2	0.019459
TRIM62	-0.019429
PLK2	-0.019429
KIAA0040	0.019411
PLOD2	0.019409
IPPK	0.019401
BACE1	0.019396
PRUNE	0.019370
NFIC	0.019347
KIAA0895	-0.019318
OVOL2	0.019308
TNS3	0.019301
SLC17A5	-0.019255
B3GNT2	0.019252
PGM3	-0.019239
DNAJB4	-0.019236
H2AFJ	-0.019232
ZBTB10	-0.019220
RAB33B	-0.019206
FAM189A2	0.019192
JADE3	-0.019170
PTGER4	-0.019164
HJURP	-0.019144
CHPT1	0.019144