!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Cisplatin
!smiles	N.N.Cl[Pt+2]Cl
!drugbank_id	DB00515
!pubchem_cid	441203
!cell_type	breast cancer cell line MCF-7
!organism	human
!end_metadata
HSPA1A	0.138551
GATA3	-0.132202
IER5	0.114929
GADD45A	0.110686
HIST1H4C	-0.107717
USP32P2	-0.094146
DKK1	-0.086146
IRS1	-0.080166
BCAS3	-0.078732
AMIGO2	-0.076899
CXXC5	-0.075226
MT1X	-0.074400
MAPK6	-0.072893
NPTN	-0.071213
TRIAP1	0.069876
ACTB	-0.068854
KPNA2	-0.067872
SERTAD1	0.067711
FAM102B	-0.066432
MT2A	-0.065659
MT1F	-0.065025
MIR21	-0.063813
DYNLL1	0.063169
BASP1	-0.062905
IRF2BPL	-0.062775
MT1H	-0.059231
GOLPH3	-0.057886
WWP1	-0.057739
SFN	0.057310
LXN	-0.055477
SLC38A2	-0.055147
ZNF217	-0.054857
MT1HL1	-0.053796
MAL2	-0.053621
RAP1B	-0.053597
TUBA1C	-0.053509
GRB2	-0.053277
YWHAZ	-0.053275
NMD3	-0.053191
CD24	-0.051426
AURKA	-0.051260
SYTL2	-0.050900
UBA2	-0.050683
USP32	-0.050612
PRR11	-0.050520
NEK7	-0.050411
LPCAT1	-0.050118
PRR15L	-0.049536
GRHL2	-0.049355
APPBP2	-0.049248
PDCD10	-0.048983
RPS6KB1	-0.048810
CTBP2	-0.048245
TUBA1A	0.048073
SLC25A6	-0.047959
SEMA3C	-0.047469
LMNB1	-0.047380
SULF2	-0.047365
PLEKHF2	-0.047258
METRNL	-0.047008
BRIP1	-0.046535
SERINC5	-0.046222
C6orf211	-0.046174
RNF13	-0.046170
MORF4L1	-0.046080
YWHAQ	-0.045764
COX8A	-0.045751
CLIC1	-0.045704
EIF3E	-0.045579
PPP1CC	-0.045548
RXRA	-0.045408
AMOTL2	-0.044713
MRPS23	-0.044624
TUBB2A	0.044569
RPL3	-0.044196
NRIP1	-0.044190
PLK2	-0.044171
TRIM37	-0.043985
CA2	-0.043832
TPX2	-0.043772
SLC25A5	-0.043665
PTGES3	-0.043664
C12orf57	0.043655
SRP19	-0.043534
MIF	-0.043106
PMAIP1	0.043084
CTDSP2	-0.043028
ANP32B	-0.042509
NDUFAB1	-0.042335
LRP11	-0.042224
UBE2S	-0.042056
KRT8	-0.042051
ZFP36L2	-0.041937
EMP2	-0.041649
PTMA	-0.041423
NR2F2	-0.041416
STAU1	-0.040972
PUM1	-0.040669
PSMC6	-0.040591
NCOA3	-0.040548
AARS	-0.040011
HILPDA	-0.040008
SLC6A14	-0.039981
SPINT2	-0.039942
PRC1	-0.039914
HSPA2	0.039795
RPL8	-0.039635
UBE2C	-0.039609
HSPA5	-0.039564
PCBP1	-0.039545
SF3B4	0.039535
HIF1A	-0.039505
TRMT112	-0.039422
TPD52L1	-0.039185
CDH1	-0.038981
NET1	-0.038434
SLC39A6	-0.038334
BZW2	-0.038059
HK1	-0.038010
YEATS4	-0.037955
CDKN1A	0.037914
SAT1	0.037852
EMC2	-0.037706
G6PD	0.037652
KANSL1	-0.037490
SMIM14	-0.037458
DEK	-0.037382
TUBB	-0.037331
MREG	-0.037279
RPL36A	-0.037226
EEF1G	-0.037097
GNAI3	-0.036890
KYNU	-0.036858
SEC24B	-0.036847
MLPH	-0.036786
RACGAP1	-0.036731
PPP3CA	-0.036715
DPM1	-0.036653
ARRDC4	0.036483
TOP2B	-0.036451
YBX1	-0.036429
EIF4A1	-0.036378
PSMA6	-0.036309
JARID2	-0.036009
TERF2IP	0.035820
KLHDC2	-0.035812
ID2	0.035749
AMZ2P1	-0.035557
MARCKSL1	0.035553
CAV1	-0.035472
CSDE1	-0.035404
POTEKP	-0.035354
OAZ1	-0.035234
RPL29	-0.035172
CTCF	-0.035067
RAN	-0.035003
CENPA	-0.034998
MIR663AHG	0.034928
KRT18	-0.034852
ERMP1	-0.034809
LYPD3	-0.034765
RAB1A	-0.034743
GAPDH	-0.034741
SEPHS2	-0.034598
KLF10	0.034517
ANXA2	-0.034490
FUT8	-0.034472
UBA52	-0.034382
GPBP1	-0.034370
TUBA1B	-0.034317
MAEA	-0.034218
CHST15	-0.034085
GDI2	-0.034008
RSRP1	0.033846
IER2	0.033811
SPIN1	-0.033774
DNAJB11	-0.033754
TXNRD1	-0.033718
ARPC1A	-0.033499
SLC7A5	-0.033401
ATRAID	-0.033337
PSMB1	-0.033198
RPS14P3	-0.032911
NUCKS1	-0.032808
IER5L	0.032791
ARL6IP1	-0.032639
ANKRD27	-0.032625
NSMCE2	-0.032466
HSP90B1	-0.032458
SLC38A1	-0.032451
HNRNPK	-0.032434
BAMBI	-0.032401
TMEM258	-0.032375
TSG101	-0.032202
ARL8B	-0.031953
OSTC	-0.031926
UBE2E3	-0.031891
VAMP8	-0.031828
ASAP2	-0.031794
CYP1A1	0.031618
NIF3L1	-0.031589
FAM83D	-0.031518
S100P	-0.031475
NRARP	0.031467
SLC7A2	-0.031334
MESDC1	0.031270
ADRM1	0.031243
PSMB4	-0.031187
RAD51C	-0.031054
RPS8	0.030992
PTPRK	-0.030748
RPSA	-0.030629
POLR2J	-0.030600
KRT19	-0.030435
RBMS1	-0.030416
LDHA	-0.030273
HEATR6	-0.030269
HMGN2	-0.030249
EPC2	-0.030130
RBBP7	-0.030076
SRSF2	0.030027
PPM1D	-0.029996
AMZ2	-0.029972
MGST1	-0.029922
RPLP0	-0.029814
CMC2	-0.029731
ESRP1	-0.029726
ANLN	-0.029717
NUP35	-0.029676
TUBD1	-0.029673
PTP4A2	-0.029598
LINC01003	0.029566
ELOVL7	-0.029541
INSIG1	-0.029477
RPL21	-0.029363
SHOC2	-0.029257
SCAF8	-0.029185
VPS37C	-0.029182
SH3BP5	-0.029063
SDC4	-0.029028
CXorf40A	-0.028971
ANXA2P2	-0.028889
TMBIM4	-0.028857
GABARAP	-0.028750
RAB8A	-0.028733
TRIM33	-0.028709
PRDX1	-0.028659
SEC13	-0.028635
FAM83B	-0.028599
LGALS1	-0.028586
ATP9A	-0.028463
NHP2	-0.028457
MB21D2	-0.028411
HSPB1	-0.028382
TOP1	-0.028322
SLC25A3	-0.028318
KARS	-0.028310
MRPL49	0.028302
ENO1	-0.028288
PFN2	-0.028274
ATP1B1	-0.028267
APP	-0.028263
H3F3B	-0.028228
ZDHHC7	-0.028216
GINM1	-0.028215
TMEM14B	-0.028204
UQCRFS1	-0.028147
RPS3	-0.028121
NEAT1	-0.028092
HAT1	-0.028033
NUSAP1	-0.028008
NOP58	0.027846
TRIM24	-0.027836
KIAA0247	-0.027832
RPA3OS	-0.027775
ABL1	-0.027710
AKR1C2	-0.027673
TUBA3C	-0.027636
MOB4	-0.027580
COX7A2	0.027511
MRPL27	-0.027450
MTCH1	0.027445
BRD2	0.027360
ADNP	-0.027294
SELK	0.027271
BCAP31	-0.027261
GLRX5	-0.027122
XBP1	-0.027111
TRIQK	-0.027058
STAG2	-0.026972
PSMC4	0.026884
FAU	-0.026831
DYNLT1	0.026809
RPS5	-0.026809
DSTN	-0.026770
ATP6V1E1	-0.026716
COIL	-0.026697
CCT7	-0.026671
ACTG1	-0.026652
GNG10	-0.026631
PMEPA1	-0.026556
DHX15	-0.026542
DNAJA1	0.026513
PPA1	-0.026461
PRMT6	-0.026442
TBC1D9	-0.026413
SGMS1	-0.026385
RPN2	-0.026359
PSMC5	-0.026350
RTN4	-0.026347
TXNIP	-0.026340
ATP6V0D1	-0.026332
RNF149	-0.026305
PIM3	-0.026180
TUFT1	-0.026163
CACNG5	0.026050
TRIM16	-0.026044
PNRC2	-0.025906
SLC2A1	-0.025898
SUMF2	0.025813
ND2	0.025784
CXorf40B	-0.025707
NOL11	-0.025705
MIR22HG	0.025684
ZFAND2A	0.025667
SET	-0.025647
NDUFB9	-0.025616
OSBPL9	-0.025510
NRAS	-0.025503
PDIA6	-0.025500
MRFAP1L1	-0.025490
DSCAM	-0.025252
P4HB	-0.025204
PTBP1	-0.025187
PSMG2	-0.025165
NME1	-0.025151
CBX4	0.025076
RPS9	-0.025045
FAM53C	0.025031
HJURP	-0.025010
WRB	-0.024975
MAP4K3	-0.024961
C1QBP	-0.024900
CBX3	-0.024867
IER3	-0.024863
MELK	-0.024842
SYAP1	-0.024840
RPS26	-0.024829
XPO6	-0.024817
MEA1	0.024793
TOB1	0.024782
RPL13A	-0.024776
NR3C1	-0.024722
SYT1	-0.024714
FOXO3	-0.024712
SF3B5	-0.024641
TEX2	-0.024622
WAC	-0.024566
PKM	0.024515
MT1G	-0.024421
DHRS2	-0.024418
H2AFZ	-0.024393
PNRC1	-0.024364
FBXO34	-0.024324
CD9	-0.024264
SSR4	-0.024221
KCNJ3	-0.024211
MRFAP1	-0.024207
APEX1	-0.024203
MTDH	-0.024181
ZNRF1	-0.024121
DDIT4	-0.024107
GPRC5A	-0.024106
PSMC3	-0.024094
SETD1B	-0.024061
RARS	-0.024038
COX6C	-0.023992
TM9SF2	-0.023930
RAD23B	-0.023851
NIPSNAP3A	0.023839
GBE1	-0.023783
RPL4	-0.023772
UBE2G1	-0.023757
SPOPL	-0.023756
UBE2R2	-0.023733
GDF15	0.023703
TMEM14A	0.023695
WBP1L	-0.023685
PCNA	0.023654
SEC11A	-0.023608
ATXN7L3B	-0.023521
LURAP1L	-0.023478
TPD52	-0.023477
PHF5A	0.023476
PPL	-0.023444
ARHGAP17	-0.023359
NDUFB3	0.023359
RPL10A	-0.023328
PPP1CA	-0.023304
ATP8B1	-0.023287
VOPP1	-0.023255
SRSF3	-0.023197
NDUFB11	0.023092
MRPS28	-0.023056
GNA13	-0.023017
ZDHHC20	-0.022995
PFN1	0.022977
TNFRSF11B	-0.022948
TRIB3	-0.022939
NQO1	-0.022919
EMC4	-0.022897
SRSF6	0.022889
EEF1B2	-0.022823
ZC3H4	-0.022815
DHX40	-0.022803
PPIB	-0.022793
GPR160	-0.022770
PICALM	-0.022758
ZNF706	-0.022749
HSP90AB1	-0.022718
CLDN7	-0.022678
ATP5B	-0.022663
LYPD6B	-0.022621
LINC00623	0.022621
VAV3	-0.022609
TKT	-0.022600
BUB1B	-0.022572
PARN	-0.022464
CDKN3	-0.022424
PPP2R5E	-0.022365
GOLGA5	-0.022364
HNRNPC	-0.022292
HMGB1	-0.022245
RPL11	-0.022233
SAC3D1	0.022212
FDFT1	-0.022111
NDC80	-0.022103
DLGAP5	-0.021911
PTTG1IP	-0.021893
UBE2E1	-0.021874
MBTPS1	-0.021851
PSMD14	-0.021815
CBX1	-0.021730
MAP2K1	-0.021718
ACTR3	-0.021663
NT5C3A	-0.021620
PRMT1	-0.021615
KCTD3	-0.021604
ANKMY2	-0.021596
SLIRP	-0.021543
RDX	-0.021530
HMMR	-0.021426
SNHG8	-0.021424
SASH1	-0.021407
MTFR1	-0.021355
JTB	-0.021331
LEMD3	-0.021307
CHCHD3	-0.021294
CNOT6	-0.021274
AGR2	-0.021261
MMADHC	-0.021259
RHPN2	-0.021259
CSE1L	-0.021238
UXS1	-0.021200
PAPOLA	-0.021156
MICU2	-0.021082
GTF2IRD1	-0.021076
TTK	-0.021072
MRPL32	0.021048
NAA50	-0.021038
FBL	-0.021023
PSMD6	-0.021014
STK24	-0.021003
CPNE3	-0.020995
S100A10	-0.020967
MSL2	-0.020960
CAST	-0.020950
CCDC6	-0.020950
FNBP1L	-0.020929
RAB5A	-0.020885
PDHX	-0.020844
LCMT1	-0.020840
C14orf166	-0.020826
MTMR12	-0.020817
SRPK2	-0.020803
PRPSAP2	-0.020801
TLE1	-0.020794
SMG8	0.020769
PSMC2	-0.020761
VIMP	0.020693
TLK2	-0.020693
COX1	0.020683
CCNG1	0.020673
PCDH10	-0.020651
YWHAE	-0.020648
RPL23A	-0.020632
FOS	0.020623
PUM2	-0.020621
MED13	-0.020581
SNRPD2	-0.020569