!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Caerulein
!smiles	CC(C(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C5CCC(=O)N5)O
!pubchem_cid	16132921
!cell_type	Pancreas
!organism	mouse
!end_metadata
KRT8	0.272493
KRT18	0.250854
ACTG1	0.230765
CHAC1	0.217062
RCAN1	0.193709
IFRD1	0.186213
REG3A	-0.172009
REG3G	-0.156356
PNLIPRP1	-0.156268
DSTN	0.148881
ACTB	0.142507
RPL4	-0.140287
HERPUD1	0.130504
SEPP1	-0.118041
DMBT1	-0.114333
NUPR1	0.111771
EGR1	0.105205
RPS3	-0.104057
HSPA5	0.103836
GGH	-0.103293
SLC3A2	0.100762
RPS27A	-0.100619
RNASE1	-0.099501
NDRG1	0.098934
GCLC	0.090967
JUND	0.084935
BTG2	0.084582
RPS2	-0.084139
GJB2	0.080078
TMED6	-0.079062
TP53INP1	0.077865
CLPS	-0.077257
ATF3	0.076271
FDX1	0.075701
EFHD2	0.075635
DDIT4	0.073530
RPS23	-0.072885
EEF1A1	-0.070190
RPL26	-0.069565
CCKAR	-0.066841
P4HB	-0.066145
RPS12	-0.064968
SSFA2	-0.064952
REG1B	-0.063857
CELA2A	0.063093
SQSTM1	0.062261
KEL	0.061750
CALR	-0.061014
GNB2L1	-0.060646
DAP	-0.060280
RPS14	-0.059814
SERPINI2	-0.059429
SLC41A1	0.058338
SPINK1	-0.057428
CDH1	0.056147
CTRC	-0.055200
CELA3B	-0.052776
CTSV	0.052435
PRSS2	-0.051478
RPL10A	-0.051026
ASNS	0.050882
IER2	0.049990
RPL27A	-0.048579
RPL38	-0.048219
CHKA	0.046647
RPS28	-0.046402
TPT1	-0.045749
PNLIPRP2	-0.045734
SAT1	0.045496
RPS29	-0.044966
FTH1	-0.044663
RPL7A	-0.044056
CSRP1	0.043997
GARS	0.043778
RPS24	-0.043222
PAH	-0.043217
RNASE4	-0.042742
RPS17	-0.042333
ACTN4	0.041984
SLC7A5	0.041859
TNFRSF12A	0.041697
REG1A	-0.041364
CDKN1A	0.040826
RELA	0.040761
TSC22D1	0.040037
DSP	0.039963
NFIL3	0.039900
AHCY	-0.038722
RHOB	0.038597
RPL3	-0.038391
SERPINB6	0.038266
RPL23	-0.038173
NARS	0.038167
EEF1G	-0.038109
PHF10	0.037681
IGJ	-0.037573
RPL7	-0.036595
ATF4	0.036025
CHCHD2	-0.035707
CEBPB	0.035402
FBXW11	0.034654
ARHGDIG	0.034189
RPS7	-0.033851
SERP1	-0.033621
ITIH4	-0.032789
RPL6	-0.032626
RPS27L	-0.032364
RPS26	-0.031421
JUNB	0.031248
KLF6	0.031194
SRSF6	-0.030990
SEL1L	-0.030646
H1F0	-0.030453
YWHAH	0.029890
TMED2	-0.029726
COL3A1	-0.029485
RPL10	-0.029460
CLIC4	0.029331
CLU	0.029276
ATF5	0.029176
TOB1	-0.029145
RPS15A	-0.028774
HSPB1	0.028439
MAP2K3	0.028424
DUSP1	0.028395
CPB1	-0.028339
RPL9	-0.028050
SLC7A3	0.027784
RPL14	-0.027627
HBEGF	0.027627
IER3	0.027384
ITGA6	0.027278
PNLIP	-0.027107
SERINC3	-0.026833
EIF5	0.026805
RPL19	-0.026494
PPIB	-0.026255
RTN4	0.026160
HIST1H1C	-0.026120
SEC61B	-0.026018
RPL28	-0.025337
MAN2A1	-0.025049
GP2	-0.024952
OSBPL2	0.024839
MID1IP1	0.024769
RPL13	-0.024716
TAGLN2	0.024623
HMGCS2	-0.024503
TRIB3	0.024447
B2M	-0.024407
APPL2	-0.024159
RPL37A	-0.024036
RGS2	0.023886
TRAM1	-0.023841
COX7A2	-0.023824
CTH	0.023790
LARP1	-0.023701
HSPD1	0.023671
RRAS2	0.023569
SSR3	-0.023554
MRFAP1	-0.023329
CCRN4L	0.023176
FGL2	-0.023152
HSP90AA1	0.023070
MSRB1	-0.023057
RPL5	-0.022828
TGIF1	0.022758
SPARC	-0.022673
RALGDS	0.022660
RPS10	-0.022638
RPL24	-0.022502
SYCN	-0.022394
PCBD1	-0.022291
RPS15	-0.022215
OAZ1	0.022067
VDAC2	-0.021991
EIF4A2	-0.021879
ETFB	-0.021813
SLC7A8	-0.021762
RPS25	-0.021736
FAU	-0.021361
CEP85	0.021276
RPL35	-0.021230
PDCD4	-0.021179
PDCD6	0.021017
RPS8	-0.020821
GATM	-0.020667
FGF21	0.020652
ARPC2	0.020649
SEPHS2	-0.020612
SLC41A3	0.020455
SNX17	0.020319
WBP5	-0.020289
HSPA8	0.020160
STARD7	-0.020134
GTPBP2	0.020108
ATP5G3	-0.020097
SMIM14	-0.020047
RPS13	-0.019576
RARS	0.019560
IVNS1ABP	-0.019546
ZYX	0.019292
ARMCX2	-0.019218
RPL13A	-0.019112
PHGDH	0.019004
RPS21	-0.018909
RNF11	0.018809
QDPR	-0.018737
CLIC1	0.018616
CNPPD1	0.018515
FAM46C	-0.018338
EIF4EBP1	0.018315
MDFIC	0.018315
SUCLG1	-0.018283
SLC38A2	0.018155
SOCS2	0.018056
MCFD2	0.018012
MYO1C	0.017796
RNH1	0.017796
SLC38A5	0.017714
TMEM131	-0.017674
TMEM147	-0.017512
RPL8	-0.017446
USP36	0.017369
NBR1	-0.017323
SPHK1	0.017314
EPN1	0.017289
PYCR1	0.017221
RPS19	-0.017183
IQGAP1	0.017132
RPL21	-0.017007
TMA7	-0.016922
YWHAG	0.016811
AARS	0.016734
SLC38A1	0.016701
COX4I1	-0.016690
POR	-0.016596
PLEC	0.016538
OCLN	0.016399
RPL15	-0.016331
SDCBP	0.016321
SFT2D2	0.016300
MAT2A	0.016233
GABARAP	-0.016147
BRD2	0.016092
EEF1B2	-0.016092
IFITM2	-0.016058
AGO2	0.016009
AZIN1	-0.016008
RPS4Y1	-0.015918
GHITM	0.015848
CLPTM1	-0.015722
PSMD8	0.015695
CLDN7	0.015644
CEBPA	0.015625
CEL	-0.015624
RHOQ	-0.015622
TM9SF2	-0.015593
C3	-0.015580
EIF3C	0.015461
TFG	-0.015433
OSTC	-0.015423
GOT1	0.015418
DNAJB9	-0.015407
PPP1R15A	0.015365
M6PR	0.015356
MTHFD2	0.015321
SMDT1	-0.015277
CFD	-0.015197
HIST1H2BI	-0.015174
SUN2	0.015140
BHLHA15	-0.015130
SPCS3	-0.015126
CLDN10	-0.015095
RPLP0	-0.015093
TM9SF3	-0.015085
PIM3	0.015046
ITM2B	-0.015029
PSAT1	0.014889
DERL3	-0.014860
OXT	-0.014851
MORC4	0.014833
MFSD6L	0.014671
GADD45B	0.014662
HGFAC	-0.014601
GRB10	0.014587
MAP3K5	0.014520
LRRC59	0.014468
PFN1	0.014459
MARCH7	0.014306
LDHA	0.014287
AMY2A	0.014263
TSPAN13	-0.014260
ERO1LB	-0.014242
NFE2L2	0.014240
NRBF2	0.014235
TAC1	0.014234
TXN	0.014222
EDEM1	-0.014216
CCDC71L	0.014197
TBRG1	0.014181
ATP5J	-0.014161
FOXM1	-0.014137
PGK1	0.014133
TJP2	0.014099
RBBP7	0.014094
HADHB	-0.014086
NDUFB7	-0.013945
ZFP36	0.013918
PPP2CA	0.013911
KLK3	-0.013909
FAM134B	0.013822
CSTB	0.013756
SRM	0.013744
NT5DC3	0.013732
MAGT1	-0.013717
CCPG1	-0.013701
PPIA	0.013669
DESI2	0.013638
EDEM3	-0.013632
RPS6KA2	0.013562
RPL12	-0.013540
BSG	-0.013483
NUDT22	0.013461
ATP5J2	-0.013427
NEK7	0.013406
TNFRSF1A	0.013369
LGALS1	-0.013308
ELL2	0.013305
PGLS	-0.013303
TMBIM6	-0.013300
MGEA5	0.013203
FERMT2	0.013188
PLA2G1B	-0.013156
CA3	-0.013150
ATP5B	-0.013136
GCAT	0.013127
SPCS2	-0.013096
PICALM	0.013012
LNX2	0.012998
GSTM1	-0.012883
VTI1B	-0.012845
COX6A1	-0.012833
REXO2	-0.012828
PPT2	0.012805
BHLHE40	0.012666
ERRFI1	0.012612
EPPK1	0.012608
TUBA4A	0.012585
MORF4L2	-0.012562
HSD3B7	0.012537
SUMO2	-0.012517
GOLGA7	-0.012500
GPAM	-0.012495
CHIC2	0.012403
HP1BP3	-0.012401
SESN2	0.012340
HELZ	-0.012307
SNX3	-0.012303
STC2	0.012212
GCH1	0.012116
HEXA	-0.012095
CYB5A	-0.012068
FURIN	0.012050
RPS20	-0.012028
PDIA3	-0.011945
YPEL3	0.011945
KIF21A	-0.011943
NDUFA3	-0.011909
IVD	-0.011867
HSPA9	0.011838
ANXA5	0.011831
ANXA3	0.011786
MAT1A	0.011778
KIAA1522	0.011756
BCKDK	0.011746
ATP5H	-0.011721
TARS	0.011713
KDELR2	-0.011712
PDLIM1	0.011688
PGPEP1	-0.011678
APIP	-0.011662
ACTN1	0.011652
C20orf24	-0.011644
MYO1D	0.011579
SDHB	-0.011562
RPS9	-0.011555
EEF2	-0.011531
MCL1	0.011517
ARF6	0.011517
CHMP5	-0.011512
TMEM230	-0.011481
DAD1	-0.011436
CTSC	0.011431
NDUFA1	-0.011426
TNIP1	-0.011419
DUSP2	0.011401
PLP2	0.011399
NOP10	-0.011390
SLC30A5	-0.011381
REEP5	-0.011331
SSR1	-0.011299
CD9	0.011258
HADH	-0.011181
RPS11	-0.011179
RPL27	-0.011143
SEP15	-0.011131
DUSP16	0.011118
PROM1	-0.011114
PPP2CB	0.011105
SDHC	-0.011020
GSTP1	-0.011007
OSER1	0.011005
CISH	0.010990
ALDH6A1	-0.010924
HSP90B1	-0.010922
AK3	-0.010902
FOXA3	0.010889
ARHGEF18	0.010866
RAN	0.010851
KLF9	0.010841
GABARAPL1	0.010824
FN1	-0.010800
PSENEN	-0.010783
SLC7A11	0.010775
BRI3	-0.010775
SEC62	-0.010760
EIF3K	-0.010727
CTRL	0.010719
CGGBP1	-0.010699
PTBP1	0.010691
SERPINB1	0.010621
CABLES1	0.010602
PPRC1	0.010593
SLC25A22	-0.010590
BCL2L1	0.010587
RPL11	-0.010574
FLNA	-0.010571
BAIAP2L1	0.010530
ARC	0.010497
ATP5A1	0.010493
COL4A1	-0.010453
MROH1	-0.010443
HSP90AB1	0.010429
ADK	-0.010403
MKNK1	-0.010402
RAB1A	-0.010394
CLTA	0.010367
UBR4	0.010367
MYH9	0.010366
ADCK4	0.010351
CARHSP1	0.010344
C18orf32	-0.010332
ASNSD1	-0.010304
SLC35F5	0.010269
ARHGDIA	0.010263
WSB2	0.010252
TRABD	0.010241
NUCB2	-0.010232
MIF	-0.010207
NDUFB11	-0.010182
CXCL13	-0.010178
EMC10	0.010173
LIF	0.010173
HNRNPC	-0.010154
EIF6	0.010146
POLR2I	-0.010145
JUP	0.010143
GNMT	-0.010089
PTGER3	-0.010081
SPCS1	-0.010060
MIEN1	-0.010023
COL4A2	-0.009998
PSMB5	-0.009980
IARS	0.009963
SOSTDC1	-0.009963
SLC1A5	0.009953
CDC42EP5	0.009918
SH3BGRL3	-0.009915
COPA	-0.009898
UBALD2	0.009897
CRIP1	-0.009871
VKORC1	-0.009806
CLDN8	-0.009797
GNB2	0.009782
C1QA	-0.009764
ODC1	0.009744
GABARAPL2	-0.009713
FABP4	-0.009631
SRP19	-0.009616
CIC	0.009597
SF3B4	0.009589
SEC11C	-0.009555
HIBADH	-0.009543
FTL	0.009530
ADSS	0.009518
RBM7	-0.009515
RPS18	-0.009506
ORMDL2	-0.009476
NFYB	0.009459