!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Cisplatin
!smiles	N.N.Cl[Pt+2]Cl
!drugbank_id	DB00515
!pubchem_cid	441203
!cell_type	A549
!organism	human
!end_metadata
CDKN1A	0.288015
RPS27L	0.241494
SFN	0.196756
S100A6	0.134784
TP53I3	0.126496
PCNA	0.115930
ALDH3A1	0.111264
PTTG1	-0.103820
AURKA	-0.103597
HSPA8	-0.101208
TYMS	0.095824
CCNG1	0.093074
TGFBI	-0.091976
DKK1	0.085803
DDB2	0.085017
SFPQ	-0.084440
CCNB2	-0.083047
TUBB4B	-0.082069
ASPH	-0.080265
PPM1D	0.076596
ODC1	-0.075187
ACTG1	-0.074546
RPL30	0.073964
RPLP2	0.072358
SRSF2	-0.072025
BTG2	0.069641
NME1	0.069420
RPL39	0.068676
CKS2	-0.068481
TOP2A	-0.067414
TNFRSF10B	0.067360
RPS12	0.067294
KRT81	-0.066504
YBX3	0.065427
CBX3	-0.063667
TAX1BP3	0.063225
IRAK1	-0.062859
SEPT9	-0.062048
CDC25B	-0.061605
AREG	-0.061556
CFL1	0.061167
EEF1B2	0.060075
MYC	-0.059994
FDXR	0.059640
MRPL33	0.059334
RPL27	0.058970
RPS8	0.058855
RPS3	-0.058473
ACTB	-0.057887
HMGA2	-0.057577
RPS28	0.056790
CDKN3	-0.056772
RACGAP1	-0.056346
KIF20A	-0.056014
RPL35	0.055773
KPNA2	-0.055558
TRIM16	-0.055173
RPS19	0.055014
MT2A	0.054485
RPL11	0.053253
SLC7A5	-0.053124
HN1	-0.052817
HDGF	-0.052058
FTH1	0.051662
CDC20	-0.051641
TPT1	0.051426
FAU	0.051286
S100A4	0.050886
KIF5B	-0.050658
C12orf5	0.050514
FAS	0.050475
PRC1	-0.050112
UBE2S	-0.049975
ALCAM	-0.049780
MDH2	0.049631
EIF5A	-0.049609
SRP14	0.049313
UBE2C	-0.048947
TPX2	-0.048937
AKR1B1	0.048812
RAB1A	0.048787
RPS3A	0.048310
ENO1	-0.047515
RPS10	0.047421
PFN1	-0.047367
SAT1	0.046954
ATP5G3	0.046392
NRG1	0.046323
RRM2	0.046156
SLC7A11	-0.045875
SCD	-0.045846
KRT7	-0.045832
MID1	-0.045070
PARK7	0.044969
RPS27	0.044932
YWHAZ	-0.044836
TXN	0.044779
RPS18	0.044778
LGALS1	-0.044738
XPC	0.043162
ZWINT	0.042608
ANXA2	-0.042395
RPL9	0.042305
PODXL	-0.042253
DUSP14	0.042075
RPL22	0.041863
NUSAP1	-0.041846
ZNF207	-0.041844
HPGD	-0.041378
LDHA	-0.041363
NDUFB1	0.041294
UQCRQ	0.041169
PRKCA	-0.041028
CCT7	-0.040769
SMS	-0.040470
DKC1	-0.040426
SERPINE2	0.040162
CES2	0.039495
ERH	0.039419
RPL32	0.038700
SNRPC	0.038657
GNG10	0.038427
COX7A2	0.038126
PRDX1	0.037905
TNS3	-0.037802
TUBA1A	0.037768
NUTF2	0.037760
HNRNPH1	0.037697
RPS16	0.037425
MRPL49	0.037273
EI24	0.037258
VCL	-0.037016
EREG	-0.036886
RPS14	-0.036857
XPO1	-0.036811
CENPA	-0.036763
COX4I1	0.036529
RPL13A	0.036492
DDX3X	-0.036331
TRAF4	0.036288
SRRT	0.036217
AKAP12	-0.035977
HIST1H2BK	-0.035961
TRA2B	-0.035926
SND1	-0.035809
PLAU	0.035694
TPM1	-0.035234
DHX15	-0.035230
RRM1	0.035088
RPL19	0.035075
CA12	-0.034829
GINS2	-0.034738
PPP2CB	0.034612
GIPR	0.034495
SHC1	0.034105
RTN4	-0.034032
CLIC1	-0.033920
VIM	-0.033750
TMED2	0.033716
RPL27A	0.033643
SOD1	0.033635
MCM6	-0.033631
ANXA1	0.033556
NCOR2	-0.033240
PFKP	-0.033090
PKM	-0.033032
JAG1	-0.032854
PGAM1	0.032834
TOP1	-0.032741
HNRNPAB	-0.032453
IMPDH2	-0.032446
GPRC5A	0.032324
DYNLT1	0.032321
RBBP7	0.032293
RBM14	-0.032221
ADM	0.032211
CD63	0.032168
ATP6AP2	0.032107
PFKFB3	-0.031897
RPL17	0.031867
RPS13	0.031518
H2AFZ	-0.031451
GADD45A	0.031284
UGDH	-0.031238
ZNF146	-0.031140
MCM3	-0.031138
DDX17	-0.031093
TUBG1	0.031076
CYP27A1	0.031073
TOB1	0.031063
B2M	0.030989
HSP90B1	-0.030619
GAPDH	-0.030225
HSP90AB1	-0.030213
NDUFA1	0.029999
HNRNPA2B1	-0.029941
CENPF	-0.029784
SRSF6	-0.029677
SDC1	0.029546
ID2	-0.029486
MTHFD2	0.029483
NDUFC2	0.029328
PRKAR1A	0.029187
PBK	-0.029155
CRYZ	-0.029082
RPL21	0.029082
DEK	-0.029054
TOP2B	-0.029047
EEF1D	0.029040
GNB2L1	0.028937
ATP5E	0.028688
MYL12B	0.028582
RUVBL2	-0.028485
MCM5	-0.028399
STRAP	-0.028359
H3F3B	-0.028355
IER2	-0.028307
ANXA4	0.028234
PCBP2	-0.028143
FLNB	-0.028109
RBMX	-0.028100
PTPRD	0.028098
HMGN2	0.028067
CCT3	0.028039
AKR1B10	0.027961
C14orf2	0.027505
CCT8	-0.027464
DUSP1	0.027397
SMC4	-0.027372
UBE2D3	-0.027358
PCBP1	-0.027327
COX6B1	0.027305
FHL2	0.027274
SNRPD1	-0.027082
OPHN1	0.027024
HMGN1	0.026960
EEF2	0.026951
PLK2	0.026818
MYL6	0.026817
RAC1	-0.026747
PPP1R3C	0.026575
MIF	-0.026530
SEPT7	-0.026526
CDK2AP1	0.026271
PRDX4	0.026219
TALDO1	0.026192
RPL18	-0.026130
NDUFAB1	0.026042
SLAMF7	0.025725
STK17A	0.025650
CTSL	0.025588
TNFAIP8	0.025433
KRT10	0.025382
LSM1	-0.025337
ITM2B	0.025332
TRIB3	-0.025307
PLP2	-0.025295
LPP	-0.025264
RPS21	0.025233
GPX1	0.025199
EIF3E	-0.025135
PLK1	-0.025035
PSME2	0.024990
KRT18	-0.024891
AURKB	-0.024869
RBM39	-0.024866
EIF2S2	-0.024727
ACTN4	-0.024704
LMO4	-0.024533
RPS15A	0.024415
NEK2	-0.024266
TRIP10	0.023973
BTG3	0.023970
CAV1	0.023966
SRGN	0.023881
AATF	-0.023807
EIF3H	-0.023791
TCEB1	0.023782
CD59	-0.023738
HPCAL1	-0.023623
ACKR1	0.023612
STAT3	0.023518
MT1X	0.023443
ABCC4	-0.023323
COX7B	0.023244
PRMT1	-0.023219
TSG101	0.023203
ALDH3A2	0.023190
ATP2B1	-0.023172
MAT2A	-0.023151
ANKRA2	0.022930
SNRPF	0.022916
NCL	-0.022782
KCNMA1	-0.022777
RUVBL1	-0.022635
RPS17	0.022567
CCT4	-0.022548
NGFRAP1	0.022520
WSB2	0.022512
C1QBP	0.022445
PTGES3	-0.022345
TXNL4A	0.022274
KRT8	-0.022259
RPL36A	0.022139
GYG1	0.022135
ARPC3	0.022132
AP1S1	0.022110
RAB13	0.022077
NT5E	-0.022072
NDUFA6	0.022056
NDUFS6	0.022024
ALX1	-0.021993
CHORDC1	-0.021830
EIF4A1	-0.021744
CNBP	-0.021731
SDHAP1	0.021657
DAD1	0.021576
TKT	0.021568
ACP1	-0.021419
PAWR	-0.021398
DBI	0.021393
BUB1B	-0.021371
NOP2	-0.021363
FKBP4	-0.021244
SQSTM1	-0.021150
RPL4	0.021143
ORC6	0.021134
YBX1	0.021014
ETF1	-0.021011
TUBB3	-0.020805
PDGFA	0.020768
VCP	-0.020654
PON2	-0.020626
KIF23	-0.020559
HNRNPDL	-0.020555
SNRNP70	0.020547
RPA1	0.020494
VDAC3	0.020476
SET	-0.020411
SF1	-0.020404
USP22	-0.020388
ATP5J2	0.020357
CHP1	0.020323
TACC3	-0.020270
UQCRH	0.020257
CDX1	0.020239
GLA	0.020191
EIF3I	0.020108
RPS25	0.020100
PPA1	0.020074
MCM2	-0.020001
ATP5G2	-0.019967
CTNNB1	0.019956
AARS	-0.019956
PROCR	0.019949
ARL4C	-0.019884
CD47	0.019869
HSPD1	-0.019865
TNFRSF12A	-0.019845
LGALS3	0.019828
TP53	0.019826
KYNU	-0.019772
G3BP1	-0.019765
CLTC	-0.019752
CTCF	-0.019741
PFDN5	0.019721
TNFRSF1A	-0.019716
ABCC3	-0.019665
HSP90AA1	0.019620
RPLP1	0.019604
POP7	-0.019587
RFX5	0.019536
ARF6	-0.019530
RPL14	-0.019527
TMSB10	-0.019486
EPAS1	-0.019485
IFITM3	0.019453
KLHDC2	0.019438
P4HA2	0.019400
TOMM20	-0.019383
POP4	0.019255
NDUFB2	0.019217
UBE2L3	-0.019202
HINT1	0.019155
PRPF8	-0.019111
PTP4A1	0.019108
SHFM1	-0.019026
ACTR2	0.019014
SARS	0.018913
DDX21	-0.018877
ZFR	-0.018870
JAK1	-0.018858
CCNF	-0.018853
CDIPT	0.018844
PPM1A	0.018829
TBCA	0.018812
HIF1A	-0.018789
UCP2	0.018746
CCPG1	0.018721
FAF1	-0.018712
CNIH1	0.018662
WDR1	-0.018655
RBM3	-0.018639
SEC62	-0.018551
ALDH1A3	0.018539
ABCB8	0.018537
PSMA2	0.018473
CYB5R3	0.018438
NEDD8	0.018382
HSBP1	0.018350
TRAP1	-0.018341
BLCAP	0.018334
MTHFS	0.018328
TIMM17A	-0.018295
SSR4	0.018290
ACTA2	0.018290
NDUFB6	0.018289
KLF10	-0.018273
BRD3	0.018272
OAZ1	-0.018246
SNRPA	-0.018240
HNRNPD	-0.018229
CD99	0.018158
TIMM13	-0.018114
YARS2	-0.018082
PTDSS1	-0.018038
LBR	-0.018034
EPHA2	0.018033
NRP1	-0.018013
ARL4A	-0.018000
MKNK2	0.017967
LAPTM4B	0.017965
CAV2	-0.017901
RHOA	0.017864
DAB1	0.017850
RSRC2	-0.017795
TGIF1	-0.017730
KIF4A	-0.017705
CDC123	-0.017700
SEC61G	0.017607
STK24	-0.017584
RRAS2	0.017575
CREG1	0.017569
TXNRD1	0.017547
TGFBR2	-0.017489
WBP5	0.017470
DNAJB1	-0.017458
HMMR	-0.017448
MAD2L1	0.017362
GRSF1	-0.017350
KIF11	-0.017326
HEBP1	0.017286
TMED10	0.017265
TCEA1	-0.017182
SLC25A15	0.017167
SESN1	0.017161
AKR1C3	0.017114
LIPA	0.017109
LASP1	-0.017101
ANXA3	-0.017057
EIF3F	-0.017030
CRLF3	-0.017026
ALPI	0.016976
RPL23A	-0.016963
PABPC3	0.016937
NCOA3	-0.016933
TIMM9	-0.016926
EIF4E2	0.016872
EIF1AY	-0.016864
ITGA6	-0.016842
RPL38	0.016761
HNRNPK	-0.016730
RSL24D1	-0.016673
PSMC2	0.016664
PIM2	0.016636
AIMP2	-0.016571
SUPT16H	0.016554
RAD51C	0.016545
SARAF	0.016543
NUP88	-0.016468
FECH	0.016352
PRR13	0.016318
PGK1	0.016302
RCN2	0.016282
TSPAN6	0.016202
ALDH9A1	0.016194
GNPAT	0.016175
RANBP1	-0.016151
UBAP2	-0.016142
EIF1	-0.016141
TMED9	-0.016088
REPIN1	-0.016037
STARD7	-0.016035
CPLX2	0.016016
NR2F6	-0.016001
GTF2A2	0.015989
WWTR1	-0.015982
UQCR11	0.015950
HSPA4L	0.015910
TFAP2A	-0.015907