!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Curcumin
!smiles	COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
!pubchem_cid	969516
!cell_type	U937 cell line (monocyte)
!organism	human
!end_metadata
CXCL10	-0.173526
S100A9	0.168109
MMP9	0.160306
TIMP1	0.154449
FTL	0.142608
MMP3	0.130054
IFI30	0.114184
FTH1P5	0.113960
IL1B	0.111271
PPBP	0.111241
IFIT3	-0.109509
CCL2	0.106337
TUBA1A	-0.104327
MMP7	0.103703
CXCL8	0.098355
HLA-B	0.097865
MMP1	0.096872
S100A8	0.096462
GAPDH	0.096135
CMPK2	-0.093017
FTH1	0.089914
UBC	0.089500
CCL20	0.088500
ACTB	0.088380
PLAUR	0.086751
TPT1	0.086566
IFITM1	-0.084254
ALOX5AP	0.083519
LAP3	-0.083359
TMEM123	-0.080912
RPL41	0.080626
INSIG1	-0.077496
TNFSF13B	-0.074905
CD83	-0.072921
PLIN2	-0.072747
RGS2	-0.070898
B2M	0.069736
VSIG4	0.069341
SPP1	0.069255
HLA-C	0.067978
SQRDL	0.066228
TALDO1	0.065921
NCF2	0.065602
IRF2BPL	0.064527
IFITM2	-0.064210
ATP6V1F	0.064070
SLA	0.063121
GLO1	0.062972
TMEM158	0.062143
RPS10	0.060439
C20orf24	0.060433
LY6E	-0.060413
EEF1A1	0.060304
EEF1B2	-0.060186
IFIT2	-0.060041
LAPTM5	0.059790
IFIT1	-0.059614
RPS18	0.058872
TYROBP	0.058631
MCEMP1	0.058084
NOP10	0.057778
TRIM22	-0.056503
JTB	0.056107
ATP6V0B	0.055408
MRFAP1	0.054983
SSR4	0.054671
HLA-A	0.054189
MX2	-0.054130
FNIP2	-0.053898
PNPT1	-0.053640
EMP3	-0.053129
MSN	-0.052078
CXCL3	-0.051646
MRPS6	0.051619
MAPK6	-0.051601
STAT1	-0.051514
AP2S1	0.051470
RPL13A	0.051267
SRXN1	-0.050735
RPS17	0.049984
ACSL1	-0.049969
DYNLL1	0.049930
RPS8	-0.049702
LCP1	0.049602
USP18	-0.049177
VIM	0.048665
SLC7A11	-0.048178
SEC11A	0.048068
MSMO1	-0.047762
MIF	-0.047743
PMAIP1	-0.047719
UBE2L6	-0.047299
CD63	0.046913
ITGA6	-0.046864
SERPINB2	0.046319
HSPA1A	0.046021
LGALS1	0.045755
CKS2	-0.044688
SNHG5	-0.044518
MYD88	-0.044422
TPSB2	-0.044032
RALA	-0.043840
LINC00657	-0.043368
OASL	-0.043293
JUN	-0.043192
MYL12A	-0.042760
FABP5	-0.042445
CCR1	-0.041992
NSMAF	-0.041641
RPS3	0.041592
GPX1	0.041574
RPS20	0.041458
CLEC2B	0.041416
HMOX1	-0.040972
CXCL11	-0.040713
NPC2	0.040706
OAZ1	0.040139
TNFRSF21	-0.039402
RPL11	-0.039350
CEBPB	0.038803
PSAP	0.038749
RAP1B	-0.038623
MMP10	0.038532
SCD	-0.038225
S100P	-0.037910
ANXA2	0.037789
RPL3	-0.037727
RPL23A	0.037675
CD93	0.037438
TTC19	-0.037341
ARL8B	-0.037162
COX1	0.037058
RPL34	0.037028
ABRACL	-0.036757
ISG15	0.036612
SUCNR1	0.036550
RPS14P3	-0.036415
SLAMF8	0.036293
ANXA2P2	-0.036253
CYP51A1	-0.036237
CTSB	0.036233
MMP12	0.036110
RPL30	0.035633
DDIT4	0.035596
IFI35	-0.035546
HERPUD1	-0.035347
RPL36A	-0.035160
PRDX1	0.035026
RPL21	0.034945
PIM1	-0.034861
RPL23	0.034609
EIF3G	0.034504
TMA7	0.034444
PPIA	0.034434
OSBPL8	-0.034415
RPS15	0.034335
PSMA7	0.034146
RGS16	0.034103
CD14	0.034067
PCBP1	0.033889
POLR2J	0.033647
ATF3	-0.033400
TMEM230	0.033355
S100A4	-0.033348
NARS	0.033327
BIRC2	-0.033316
NFKBIA	-0.033032
FLNA	-0.033002
IL1RN	-0.032988
HNRNPK	-0.032895
CCL1	0.032430
MAFF	-0.032284
RPL32	0.032160
MIR22HG	-0.031986
YWHAZ	-0.031898
SRGN	0.031822
PDK1	-0.031733
TAP1	-0.031586
VEGFA	0.031431
ATP6V1E1	0.031188
BZW1	-0.031152
CAPNS1	-0.031028
UBA52	0.030939
CITED2	-0.030937
MEA1	0.030890
PPIF	-0.030845
TDO2	0.030586
TNFAIP3	-0.030351
DYNLT1	-0.030297
PPP1R15A	-0.029988
RPLP0	0.029805
OAS1	-0.029632
RGS1	-0.029603
RNASE6	0.029471
SMS	-0.029409
SPPL2A	-0.029207
GPR84	0.029101
EEF2	-0.029081
EIF1	-0.029011
MNDA	-0.028940
SEC61B	-0.028936
IFNGR2	-0.028874
TMBIM1	0.028866
KPNA2	-0.028844
MTHFD2	-0.028736
SLC25A3	-0.028518
MRPS24	0.028504
NACAP1	-0.028463
RPL37A	0.028442
RRAGC	-0.028358
DUSP1	-0.028351
LAPTM4A	0.028234
COL22A1	0.028062
FCER1G	0.028013
LRIF1	-0.028012
CDIPT	0.027895
IER2	-0.027890
ATF4	-0.027790
TUBA4A	0.027683
HMGN1	0.027679
METRNL	0.027631
CAPG	-0.027613
ATP1B3	0.027554
ALDOA	0.027468
KLF6	-0.027423
FXYD5	0.027392
CD52	-0.027146
DEDD2	-0.027130
RBM3	-0.027065
NACA	0.027031
PTDSS1	0.026971
TXNRD1	-0.026909
SEC13	0.026898
LGALS3	-0.026895
H2BFS	0.026794
PTX3	-0.026778
RHOA	0.026715
NDUFA13	0.026701
PPIB	0.026613
B3GNT2	-0.026610
NDUFB9	0.026597
MT1HL1	-0.026549
ISG20	-0.026489
MAP1LC3B	-0.026323
TIMMDC1	0.026302
CSTB	0.026237
CLIC1	0.026206
IFITM3	-0.026107
PSMD8	0.026033
HIST1H2BD	0.025788
DNAJB9	-0.025769
PSMA1	-0.025732
CCL8	0.025706
MESDC1	-0.025604
HS3ST2	-0.025588
RPS12	0.025558
CCL7	0.025543
NEU1	0.025520
GLA	0.025441
PYCARD	0.025424
HUWE1	0.025397
SRP9	-0.025362
SLC20A1	0.025342
ITM2B	-0.025112
TPSAB1	-0.025041
RPS9	-0.025032
RAB13	0.025010
GPR34	0.024861
STARD4	-0.024813
MRPL34	0.024743
CLEC5A	-0.024732
EIF4H	0.024725
PTTG1IP	0.024633
B4GALT5	-0.024615
NDRG1	0.024574
GPR183	-0.024347
SOD1	0.024247
RPS28	0.024242
RPL17	0.024230
PRDX4	-0.024091
OST4	0.024021
DTX3L	-0.023992
MGAT1	-0.023969
PFDN5	0.023934
SNRPG	0.023915
FAM96B	0.023821
CD164	-0.023759
FCGR1B	-0.023728
UFC1	0.023634
RPN2	0.023597
PLSCR1	-0.023535
RSAD2	-0.023495
NRAS	-0.023419
ITGB2	-0.023414
HSPB1	0.023398
SEPW1	0.023329
FCAR	-0.023285
TUBB2A	-0.023246
MRPL14	0.023219
NFE4	0.023130
DENND5A	-0.023121
FAM96A	0.022840
CFL1	0.022807
NFKBIZ	-0.022778
RPL26	-0.022657
SEP15	-0.022621
MIR155HG	-0.022503
NDUFV2	0.022282
UPP1	0.022252
SNRPD2	0.022250
PILRA	0.022150
COX6B1	0.022146
DPM1	-0.021989
TUBB	0.021895
PFDN2	0.021879
LASP1	-0.021844
MYADM	-0.021813
EFR3A	-0.021800
PEA15	-0.021719
IER3	0.021658
CHMP5	-0.021550
UBE2S	-0.021421
HK2	-0.021385
ABHD3	-0.021369
RAB11A	0.021355
TDP2	-0.021243
ABL2	-0.021242
PABPC3	0.021195
YRDC	-0.021177
COX3	-0.021034
PSMB5	0.020983
SLC17A5	-0.020951
UBE2E1	-0.020912
RPL27A	0.020905
DDX3X	-0.020900
NDUFA4	0.020818
CAP1	0.020790
HPCAL1	0.020753
LITAF	-0.020698
MOAP1	-0.020598
COX2	0.020543
CSTA	-0.020522
DPYSL2	-0.020518
DCSTAMP	0.020494
CDKN1A	-0.020478
RAC2	0.020431
IFI16	-0.020332
BCL2A1	0.020268
DUSP14	-0.020263
TMEM163	-0.020233
SNRPD3	0.020219
ZNFX1	-0.020208
TCEB1	-0.020158
FCGR2A	0.020135
HNRNPH1	-0.020134
C15orf37	-0.020125
CXCL2	-0.020104
SAMD9	-0.020103
CES1	0.020068
RPL39	0.020050
TMBIM6	0.020038
RPS27	0.020038
RPL5	-0.020035
SMIM3	-0.019984
RPL9	0.019935
NFE2L2	-0.019897
IARS	0.019810
SNX3	0.019712
ATP6	0.019624
C14orf166	0.019621
CRELD2	0.019597
COX6C	-0.019526
CCT4	0.019439
EMP1	-0.019391
GABARAP	0.019314
TXNDC12	0.019274
YWHAQ	-0.019259
IRS2	0.019246
TUBA1C	0.019214
KLF10	-0.019197
SP110	-0.019077
NOTCH2	-0.019057
ACADM	-0.019040
MRPL33	0.019002
BCAP31	0.018828
CSNK2B	0.018779
H2AFZ	-0.018742
IFI6	-0.018662
COA6	0.018533
FAM35A	-0.018440
APBB1IP	0.018392
PTPLAD1	0.018391
HLA-E	-0.018358
SLC5A3	0.018344
SLC7A7	0.018303
CHCHD2	0.018291
CHSY1	-0.018242
GPX4	0.018222
SNHG16	-0.018177
MRPL36	0.018127
IL4I1	-0.018125
FAU	-0.018083
RPS27A	-0.018077
ISCU	0.018044
CCNA1	-0.018041
HSPA6	0.017994
GMFB	-0.017971
VAMP8	0.017960
ACAT2	-0.017950
CHCHD1	0.017914
PLEK	-0.017903
C3	-0.017859
PSMD4	0.017842
DDX58	-0.017839
IRF7	-0.017788
TMBIM4	0.017782
PFN1	-0.017747
RGS13	-0.017626
SMAP1	-0.017607
GLRX	0.017563
NDUFB3	0.017551
NDUFAF1	0.017544
PPP1R15B	-0.017542
NABP1	-0.017487
DDX39A	-0.017474
CORO1A	0.017465
DAD1	0.017462
RASSF5	0.017437
OAS3	-0.017421
RPLP1	0.017384
CHI3L1	0.017298
SOD2	-0.017272
RPS2	-0.017266
DUSP6	-0.017264
RYBP	-0.017249
ANXA1	-0.017247
PARP12	-0.017191
IDI1	-0.017156
S100A6	0.017127
RPL28	0.017104
BEX1	0.017080
TPI1	-0.017077
DDX60	-0.017030
EIF2AK2	-0.017030
ANKRD28	-0.017020
CST7	-0.016980
SGK3	0.016955
SLC26A11	-0.016909
LACC1	-0.016864
CDC42EP3	-0.016857
MT1E	-0.016855
NPC1	-0.016849
IRAK1	-0.016774
EVI2A	0.016686
LAMTOR5	0.016667
COX7A2L	0.016661
NEDD8	0.016656
PSME2	-0.016640
THBD	-0.016635
COMMD7	0.016633
CYBB	-0.016626
NMB	0.016498
TMX1	-0.016491
NAA50	-0.016443
AHSA1	0.016395
GRN	0.016264
HCAR3	-0.016237
ATP2B1	-0.016221
EEF1G	0.016216
CALM2	0.016194
PSMD14	0.016140
ATP6V1D	0.016139
CSGALNACT2	-0.016096
UBL5	0.016089
BCL6	0.016074
QARS	0.016071
OLR1	0.016058
OLIG1	0.016039
LTA4H	0.015974
ZMPSTE24	0.015959
SRSF2	-0.015950
EGR2	-0.015933
RPN1	-0.015924
BTG1	-0.015905
CTSA	0.015885
C1orf122	0.015875
DPY30	0.015793
CTNNB1	-0.015787
PSMB8	-0.015746
MT1X	-0.015738
LEPROTL1	0.015724
METTL23	0.015712
PLEKHO2	-0.015687
SCARB2	-0.015588
NDUFS3	0.015548
SHOC2	-0.015535
ASS1	-0.015528
RHOQ	-0.015496
DAP	0.015490
KIAA0101	-0.015445