!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Doxorubicin
!smiles	CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
!drugbank_id	DB00997
!pubchem_cid	31703
!cell_type	A673
!organism	human
!end_metadata
HIST1H2BK	0.182338
HIST1H2BD	0.167799
MMP1	0.167351
KRT18	0.133066
YPEL5	0.108099
HIST1H2AC	0.100157
ARL6IP1	0.093429
CES1	0.090093
NELL2	-0.080182
AKAP12	0.079996
MRPL3	-0.077896
ANXA1	0.076696
HMGN2	-0.075494
BTG1	0.075070
FUCA1	0.074304
SDCBP	0.074055
TRIB1	0.071856
MEST	0.069633
OAT	0.069603
CKS2	0.069528
ANP32B	-0.069446
PFN2	-0.067750
TFPI2	0.066525
PSMA1	-0.066346
TRMT5	-0.065659
PTGES3	-0.063986
TAGLN2	0.062985
LBH	0.062691
IARS	-0.062387
GNG11	0.061100
RAB13	0.060538
RND3	0.060301
HIST1H4C	-0.059566
CDK1	0.059324
UBE2C	0.059323
HINT1	-0.057436
EEF2	0.057303
PSMD14	-0.057248
TUBB	-0.055994
GLRX	0.055494
HIST2H2AA3	0.054866
SSR2	-0.054167
TNFAIP6	0.053616
TUBB2A	0.052898
SLC25A5	-0.052419
ITM2C	0.052379
IDH1	-0.052277
ARMCX3	0.052068
TOR1B	0.051731
GMNN	-0.051570
MKNK2	0.051555
PCBP1	-0.050868
B2M	0.050739
ACAT2	-0.050291
TXNDC5	-0.050278
VIM	0.050176
GINS1	-0.049997
DLK1	0.048867
GLO1	-0.048753
DHX15	-0.048325
CD63	0.048291
AURKA	0.048148
LMNB1	-0.047044
SRSF3	-0.047017
NRD1	-0.046428
GLA	0.046295
HSPD1	-0.046177
IFITM3	0.045893
TMEM97	-0.045866
NHP2	-0.045724
TUBB2B	0.045687
TUBB6	0.045619
ARMCX6	0.045611
HMGN3	-0.045595
MMP3	0.045503
PCNA	-0.045132
HMGB1	-0.044606
TIMP1	0.044561
GRP	0.044340
ITM2A	0.044156
PTMA	-0.044143
XRCC5	-0.044062
ATF4	-0.044052
ATP1B3	0.043889
HPRT1	-0.043601
PHB2	-0.043551
HSPA1A	-0.043250
EFNB2	0.043220
HNRNPA2B1	-0.043149
GARS	-0.043120
ZNF280A	0.042984
ARPC5L	0.042951
NR0B1	0.042884
SRSF2	-0.042778
SSRP1	-0.042577
BLCAP	0.042493
TMSB15A	-0.042437
NPY1R	0.042088
VCP	-0.042058
RGS5	0.042003
PNP	0.041846
RPL3	-0.041360
CCT7	0.041329
PKIG	0.041011
ASNS	-0.040967
CEBPB	0.040962
KIAA0101	-0.040926
PODXL	0.040877
PHLDA2	0.040818
NME4	-0.040796
MAFB	0.040661
LY96	0.040104
YARS	-0.039718
HSPB1	0.039405
FDFT1	-0.039378
HNRNPR	-0.039365
CCT3	-0.039300
MTCH1	0.039150
CCT5	-0.039052
PSMD1	-0.038971
HCLS1	0.038950
TMEM106C	-0.038939
HDAC1	0.038840
TGIF1	0.038751
SLC35F2	0.038694
JTB	-0.038507
PSMC3	-0.038506
ARHGAP29	0.038501
COX6B1	0.038383
MAP1LC3B	0.038355
ATP1A1	0.038117
PBK	-0.038096
TUBA1C	0.037973
CCNB1	0.037919
CXCR4	0.037862
IRAK1BP1	-0.037834
PPA2	-0.037596
MSX1	0.037533
IER3	0.037482
NCKAP1	-0.037463
CDC20	0.037415
EIF4EBP1	-0.037366
FADS1	-0.037221
OLFML3	-0.037026
KIF20A	0.036969
MLLT11	-0.036908
GCSH	-0.036902
KDM3A	0.036899
GINS2	-0.036833
NPY	0.036479
CHST6	0.036414
POLR3K	-0.036356
KRT8	0.036316
CTSL	0.036197
MAPK6	-0.036180
FTH1P5	0.036175
ZFAND5	0.036171
XPOT	-0.036152
PTPRK	-0.036140
DUT	-0.036075
RPS27	0.035981
SARS	-0.035715
UBE2E3	-0.035677
HIST1H2BH	0.035628
CXCL8	0.035267
IMMT	-0.035203
GCH1	0.035038
HAX1	-0.034955
EMG1	-0.034945
SRP14	0.034819
GMPS	-0.034347
EDF1	-0.034271
TBCB	-0.034202
SCD	-0.034192
H2AFY2	-0.034118
GJA1	0.034093
CHCHD2	-0.033951
MATR3	-0.033917
PTTG1	0.033624
CKS1B	0.033613
PSMA4	-0.033378
SGK1	0.033192
ITGB3BP	-0.032986
ANXA2	0.032976
PSMC1	-0.032968
RPL28	0.032957
EIF3H	0.032957
RPA3	-0.032940
DDIT3	0.032752
PDE1A	-0.032447
CDC37	0.032360
HIST1H2BE	0.032338
APLP2	0.032309
FLNC	0.032079
LITAF	0.031990
CLTC	-0.031933
MSMO1	-0.031927
NME2	-0.031802
SLC5A3	0.031505
MARS	-0.031449
MLH1	-0.031402
DPM1	0.031345
CAPRIN1	-0.031176
CORO1C	0.031167
RBBP7	-0.030812
UAP1	0.030767
PDCD6IP	-0.030665
TPM2	0.030559
BANF1	-0.030558
CBS	-0.030513
CKB	0.030362
ODC1	-0.030361
PTTG1IP	0.030335
TRIB2	0.030290
NDUFAB1	-0.030248
DNAJB6	0.030093
IGFBP2	0.030093
SNAP23	0.030057
P4HB	-0.030038
IDI1	-0.029987
PSME2	0.029928
NSA2	-0.029894
THY1	0.029790
PSMC6	-0.029777
HMMR	0.029738
ARF4	0.029710
STX3	0.029652
HJURP	0.029569
UBA1	0.029469
CENPE	0.029435
OAZ1	-0.029409
AKR1A1	-0.029408
SEH1L	-0.029263
DKK2	0.029085
CXADR	0.029052
POLR2I	-0.029031
GTF2E1	0.028951
HYOU1	-0.028943
HIRA	-0.028896
ZNF146	-0.028876
LSM1	0.028857
TOP2A	0.028751
ANP32E	-0.028747
SNX3	-0.028730
KARS	0.028729
PABPC3	0.028720
LRPPRC	0.028709
FOS	0.028681
STRA13	-0.028679
HADHB	0.028648
S100A10	0.028597
EIF4A2	0.028548
MRPL39	-0.028446
CSRP1	-0.028418
NET1	0.028382
PEA15	0.028291
FAM171A1	-0.028259
SRI	-0.028141
PIR	-0.028088
RPS16	-0.028068
NPC2	0.028036
SDC4	0.028022
HLA-A	0.027996
RPL39	0.027944
RPL21	0.027879
HOOK1	-0.027753
VBP1	-0.027747
PSAP	0.027704
ATP6V0D1	0.027686
CKAP4	-0.027600
MRPL49	-0.027547
C20orf24	0.027450
KIAA0907	0.027378
RPS18	0.027357
PLS3	0.027293
GLG1	-0.027209
KLF10	0.027162
COX6A1	0.027149
CCNB2	0.027130
C1QBP	-0.027118
PRNP	0.027051
BZW2	0.026953
ATP6V1G1	0.026924
PSMD7	-0.026892
GPX4	-0.026756
ASNSD1	-0.026706
PARK7	0.026543
SNRNP25	-0.026538
GNPAT	-0.026473
UBA52	0.026454
COX7B	0.026426
BASP1	-0.026385
ZWINT	-0.026329
RIN2	0.026286
STEAP1	0.026239
TPT1	0.026158
ARL8B	0.026143
CCNB1IP1	0.026073
RFC4	-0.026072
FAM53C	0.026066
HSPA8	-0.025998
TSPAN13	0.025975
RBBP8	-0.025912
HN1	0.025911
ACTG1	-0.025900
PPIB	-0.025873
PLK2	0.025868
SEC61G	-0.025861
FADS3	0.025832
SERINC1	0.025826
TRA2B	-0.025824
CYC1	-0.025818
CCNG1	-0.025744
ITM2B	0.025710
PPIF	0.025697
WDR26	0.025684
MTHFD1	-0.025681
BIRC2	0.025649
RPL10A	-0.025574
HEXB	0.025546
MGST3	0.025517
IER5	0.025462
TMSB10	0.025440
PFDN5	0.025426
PRIM1	-0.025409
LASP1	0.025402
DLD	-0.025337
GNB1	-0.025292
ARPC2	0.025285
ACTB	-0.025281
CYP51A1	-0.025277
CAPNS1	-0.025264
TOMM7	-0.025244
FTH1	0.025240
UBE2A	0.025178
FAM21A	0.025117
RAN	-0.025115
MIF	-0.025085
SKP1	0.025064
S100P	0.025018
SNRPB2	0.025003
GSTA4	-0.024993
HSD17B4	-0.024962
NSMCE4A	-0.024925
RPL6	0.024904
DENR	0.024847
AHCY	-0.024770
TCEA1	-0.024769
TAF9	0.024768
ATP6V1D	0.024765
CDK2AP1	-0.024761
RCC1	-0.024694
C8orf4	0.024631
ESD	-0.024584
NPTN	0.024582
CENPU	-0.024546
CS	-0.024509
H1FX	-0.024445
FAM35A	-0.024433
CTCF	-0.024307
CECR5	-0.024134
FAT1	0.024026
UBAP2	0.024010
SLC24A3	-0.023942
SAC3D1	-0.023921
WBP5	0.023912
RPL12	0.023869
ACTN1	0.023859
RPL11	0.023824
VAMP3	0.023810
RPL32	0.023731
UQCRH	0.023635
MOAP1	0.023630
AP2S1	-0.023620
SOD1	-0.023612
DARS	-0.023594
GTF3A	-0.023573
PTX3	0.023552
TUBB3	0.023535
RRM1	-0.023530
PACSIN2	0.023415
TAX1BP3	0.023362
FBN2	-0.023328
PPP1R14B	-0.023290
CDKN1A	0.023280
H3F3B	-0.023267
SHMT2	-0.023257
ATP5C1	-0.023244
USP33	0.023166
RPL36	-0.023154
FAM136A	-0.023089
RCOR1	0.023062
HIST2H2BE	0.023037
GOT2	-0.022970
NUCKS1	-0.022913
SOX9	0.022877
TWIST1	0.022859
ATP5B	0.022845
RBM39	-0.022837
SSR4	0.022811
ENY2	0.022796
APIP	-0.022733
KPNA2	0.022722
IFRD1	0.022605
LSG1	0.022548
PHIP	-0.022539
GNG12	0.022529
PFKP	-0.022494
PARP2	-0.022483
UCHL1	0.022431
POLA1	-0.022392
DDX1	-0.022359
VWA5A	0.022352
UBE2L6	0.022352
PPT1	-0.022341
CARM1	-0.022308
ID3	-0.022301
HIST3H2A	0.022251
EIF2B2	0.022238
PPID	-0.022206
CISD1	-0.022118
PRDX4	-0.022112
ADRM1	-0.022060
EPRS	-0.022048
MYL6	0.022001
HNRNPAB	-0.021927
FTL	0.021833
RRAGC	0.021831
RUVBL1	-0.021813
SNRPA	-0.021800
CSE1L	-0.021786
LRRC47	0.021777
COL4A2	0.021746
DHCR7	-0.021710
HNRNPA3	-0.021707
ATP6V1B2	0.021690
LAPTM4A	0.021688
HK1	0.021681
MAP1B	-0.021674
U2AF1	-0.021673
FSTL1	0.021661
UNG	0.021641
SMAGP	0.021634
JAG1	0.021626
CD164	0.021621
SEC61B	0.021616
CALM2	0.021609
SRSF9	-0.021582
PXDN	0.021499
HSPA9	-0.021498
AKIRIN1	0.021489
UCP2	-0.021439
FKBP1A	0.021420
UCK2	-0.021412
LSM3	0.021393
FNTA	0.021300
ATP5H	0.021273
RPS9	0.021168
SHC1	0.021108
NDUFB6	-0.021053
FDPS	-0.021026
GLRX5	0.021025
BBS4	0.021024
CD81	0.021023
TTK	0.020974
AMD1	0.020944
TMEM59	0.020937
CKAP5	0.020910
RPS29	0.020907
DCLRE1A	-0.020900
PSMA5	-0.020898
RNF114	0.020893
EPHB3	0.020890
CDC34	0.020837
PDIA6	-0.020821
RPL29	-0.020762
SRSF1	-0.020753
ALDH18A1	-0.020752
RNASET2	0.020719
SLC39A14	-0.020701
DCXR	-0.020668
GMFB	-0.020645
CLNS1A	0.020626
HAT1	-0.020619
HDLBP	0.020605
HSPA4	-0.020594
CLTA	0.020585
CLDN5	0.020557
MRPL12	-0.020509
TRIM28	-0.020482
TALDO1	-0.020411
SRM	-0.020408
PHGDH	-0.020406
RPS13	-0.020398
HSD17B7	-0.020334
NAT10	-0.020325
EIF3D	0.020292
BAG6	-0.020268
ATIC	-0.020235
PAPSS1	0.020226