!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!gene	LRRK2
!cell	iPSC
!perturbation	Parkinson's disease  homozygous LRRK2 mutation
!disease	Parkinson's disease
!end_metadata
CHCHD2	0.165155
DLK1	-0.153104
LEFTY1	0.131410
ACTA1	0.124730
PEG3	-0.103438
SIX3	-0.097150
NTS	0.091079
ZEB2	-0.090573
PAX6	-0.083228
DACT1	0.083213
ZNF492	-0.082860
ZIC1	-0.079064
FLRT3	-0.076778
HIST1H2AC	0.073155
MOCOS	-0.071287
FRZB	-0.070716
CRYZ	0.068905
LMO1	-0.066175
ANXA1	0.065354
EPHA4	-0.065077
LGI1	-0.063376
HIST1H2BK	0.063069
ANXA3	0.062965
CYP26A1	-0.060916
ARHGAP15	-0.059437
PAMR1	-0.058687
LEFTY2	0.057544
POMZP3	-0.057215
TAGLN	0.056690
LMO3	0.056483
ANO1	-0.055736
SOHLH2	-0.055361
HESX1	-0.055188
PIEZO2	0.054627
SLFN12	0.052835
PCDH8	-0.050385
GSAP	-0.050104
TRPC4	-0.049952
LHX2	-0.049786
SRY	-0.049304
CAV1	0.049224
SPP1	0.048738
ID4	-0.048491
IER3	0.048370
IRX5	-0.048314
CHODL	0.047421
COL6A3	0.047322
FEZ1	-0.046761
GNA14	0.046708
BCHE	0.046344
SERPINB4	0.045990
MAP3K8	-0.045834
ACTG2	0.045826
CDH6	-0.045819
FST	-0.044808
NLRP2	-0.044561
SNHG17	0.044444
KLHL4	0.044194
FAM189A2	0.044138
COL5A2	0.044134
RAB17	0.043911
AHNAK2	-0.043488
TNIK	0.043352
ID2	-0.042790
ELP5	-0.042708
MUC4	-0.042508
EOGT	0.041974
ORM1	-0.041792
H2BFS	0.041518
SOAT1	-0.040961
CTSK	0.040916
ENC1	-0.039854
NCAN	-0.039730
TRIM22	-0.039649
NLGN4Y	0.039346
PDGFD	0.038873
PDLIM3	-0.038810
CDKN1A	-0.038783
LCP1	0.038575
PITX2	0.038530
CSRP1	0.038409
LIMCH1	-0.038351
KAT2B	-0.038080
SLIT2	0.038043
DDIT4	-0.038006
NR2F2	-0.037989
CDH9	-0.037914
HEY2	0.037490
HIST1H1C	0.037425
MEIS2	-0.037353
MLLT4-AS1	-0.037316
TAC1	0.037287
GPC3	-0.037186
MYH2	0.036853
PDE4B	0.036732
AMIGO2	0.036587
FJX1	-0.036542
ARID5B	0.036399
VWF	-0.036380
GLTP	0.036286
TNFAIP6	0.036217
TIMP4	0.036054
CHGA	0.035877
OGFRL1	0.035714
ACTN3	-0.035505
DKFZP564C152	0.035437
RARRES3	-0.035332
SLC39A4	0.035262
FHOD3	-0.035035
BBS9	-0.035032
SERPINB3	0.034934
TMEM158	-0.034860
DDX58	-0.034699
CXCL3	0.034601
FBN2	-0.034323
DDB2	-0.034273
LPAR6	0.034240
VIL1	0.034191
RWDD2B	0.034085
PLEKHB1	-0.033876
BST2	-0.033856
ZNF257	-0.033601
DUSP6	0.033589
ADRA2A	-0.033582
SOX3	0.033571
CXCL5	0.033570
SMAD7	0.033349
SPINK2	-0.033132
AMOTL2	0.033032
TTN	0.032975
GALNT12	-0.032752
SLC7A5	0.032328
ELTD1	0.032268
FOS	-0.032161
CHP2	-0.031861
GATA6	0.031799
LGR4	-0.031488
LRRC2	0.031452
AKR1C3	0.031449
FOXL2	0.031420
AFP	0.031404
ZBBX	-0.031361
PCSK1	-0.031353
MYL9	0.031161
DUSP5	0.030981
GCNT1	-0.030840
TM7SF3	-0.030797
TIMM22	0.030763
ZIC3	-0.030613
ARSJ	0.030408
PDZD2	0.030393
TMEM255A	-0.030137
GREB1L	-0.030121
CELSR2	-0.030036
PLA2G7	-0.029913
PRKCQ	0.029807
S100A11	0.029648
PPP1R17	0.029476
CRYBB2P1	0.029333
CCNG2	-0.029310
PPP1R16B	0.029205
STRN3	0.029140
SOX11	-0.029013
MYO1D	0.029011
RBM47	0.028975
EGR3	-0.028923
SLC8A2	-0.028863
CAV2	0.028811
HIST3H2A	0.028761
LOC389906	0.028579
CCDC177	-0.028545
EIF1AY	0.028295
SAMHD1	-0.028055
NID2	-0.027915
CHRNA9	0.027887
FGFR3	-0.027688
TGFB1I1	0.027654
MFHAS1	-0.027552
PRR16	0.027527
TUBBP5	0.027507
MDFIC	0.027482
PSMB9	-0.027479
OSGEP	0.027475
CYBRD1	0.027449
KLKB1	-0.027365
NT5E	0.027348
NR5A2	0.027256
CXCL6	0.027221
JAKMIP2	0.027122
DNALI1	-0.027099
PRPH2	0.027074
CNTNAP2	-0.026850
PILRB	-0.026848
APOBEC3B	-0.026822
NEDD9	0.026767
ITGB5	0.026675
WLS	-0.026675
CXCL2	0.026643
ZBED8	-0.026617
ASS1	-0.026571
FBXO2	-0.026551
PDYN	-0.026522
AOC3	-0.026494
LEPREL1	-0.026471
ACTC1	0.026450
PAPOLG	-0.026422
STMN2	-0.026256
KCND2	0.026239
KCNN2	-0.026215
CACNB3	-0.026198
CPNE1	-0.026059
ANPEP	-0.026021
MAF	-0.025881
SCG3	0.025858
CD52	-0.025812
HIST1H2BD	0.025790
ST6GALNAC5	-0.025783
USP3	0.025701
ZHX2	0.025666
CYTL1	0.025602
PPFIA4	-0.025572
GSTM2	-0.025532
CYR61	0.025530
FAM189A1	0.025525
EFNB2	-0.025490
COLEC12	0.025415
RAB3B	0.025408
MICA	-0.025392
AK4	0.025381
MMP9	0.025374
TEX14	0.025323
TTYH1	-0.025322
BRINP1	0.025315
PLSCR4	0.025310
PPIC	0.025307
GNG11	0.025293
ITM2A	0.025279
GAD1	-0.025199
FGF13	0.025096
DKK1	-0.025064
PHLDA3	-0.025047
PCDHA2	-0.025012
LRP2	-0.025011
PRR5L	-0.024948
MYL7	0.024935
LDHC	-0.024908
MN1	-0.024874
SERPINE1	0.024858
FOSL1	-0.024798
PWAR5	-0.024779
CES1	0.024765
HYAL4	0.024743
ADAMTS5	0.024721
EGR1	-0.024688
ABCA1	-0.024612
NQO1	0.024584
USP36	-0.024566
LOC100272216	-0.024532
LRP10	0.024518
MME	0.024493
SALL1	-0.024459
VCAM1	-0.024438
OXTR	0.024374
DPY19L4	-0.024367
KLF4	-0.024317
NPTX2	-0.024255
CLCN2	-0.024196
GLS2	-0.024146
ZNF682	-0.024137
EFS	-0.024027
SNX16	0.024005
CST1	0.023994
CNKSR2	-0.023931
TES	0.023921
WDHD1	-0.023879
DENND1A	0.023756
GNMT	-0.023747
SESN1	-0.023699
CTNNA2	-0.023681
DPEP3	0.023679
MXRA5	-0.023610
LYN	0.023498
ANKHD1	-0.023481
OXSM	0.023478
CXCL14	0.023376
MAFF	0.023310
ICAM3	0.023307
BTG2	-0.023295
HNMT	0.023277
NPPB	0.023109
SLC24A3	0.022991
ADAMTS1	0.022990
INPP5D	-0.022980
LRRN3	-0.022934
ATP1A2	-0.022903
LOC730101	-0.022867
NNAT	-0.022834
PEA15	0.022800
HLA-DRB1	-0.022756
SYN3	-0.022742
GPC4	0.022703
RAPGEF2	0.022689
COL13A1	-0.022664
FAM149A	-0.022663
IFI16	-0.022661
TJP3	-0.022632
JAK1	0.022617
RHOH	0.022607
GPR3	0.022600
ST8SIA3	0.022556
APLP1	-0.022515
CTGF	0.022478
IGFBP4	0.022468
MTHFD2L	0.022439
MYC	0.022381
ADCY7	-0.022364
KCNN3	-0.022359
CREB5	0.022344
MUTYH	-0.022332
TAF1A	-0.022298
MYBPC2	-0.022277
PAAF1	-0.022255
GSTM5	-0.022237
GSTO1	0.022235
PLBD1	0.022206
DPP6	-0.022144
ANKRD36	-0.022127
DND1	-0.022102
GUSBP3	-0.022088
MDK	-0.022059
CSAD	-0.022054
MCOLN3	-0.022051
FUT8	-0.022039
TIMP3	0.022033
UPK1A	-0.021993
PTPN4	-0.021969
PLA2G16	-0.021964
IGFBP7	0.021950
DTX2	0.021938
CLC	-0.021894
EVA1B	0.021882
VSNL1	0.021866
ETNPPL	0.021808
GOLGA8B	-0.021804
ANKRD7	-0.021698
NLGN1	0.021685
ST20	0.021675
OTUB2	-0.021669
BMP7	-0.021666
PLA2G4C	0.021643
GALR1	0.021642
BOLA1	-0.021626
GDAP2	0.021612
CLU	-0.021583
TFAP2C	-0.021542
TRMT1L	-0.021531
ACTA2	-0.021520
ZNRD1-AS1	-0.021509
ZNF208	-0.021481
CPS1	-0.021375
DPYSL3	-0.021375
LPL	0.021367
GYPC	0.021367
PLP1	-0.021349
RASL11B	0.021324
MCM3AP-AS1	-0.021269
LHFP	0.021257
CER1	0.021203
ALDH6A1	-0.021155
INPP5F	-0.021134
MIR22HG	0.021122
RND3	0.021073
ENO2	-0.021069
SIRT1	-0.021066
USP9X	-0.021037
BZRAP1	-0.021023
SLC39A8	0.020994
GSE1	-0.020990
SPON1	-0.020950
FAM129A	0.020907
DHRS2	0.020878
CEMIP	0.020832
TRBC1	0.020810
SYN1	0.020809
TWIST1	0.020804
SLC1A1	0.020765
TESC	-0.020649
ADAMTS8	0.020647
DAB2	0.020533
ZFHX4	-0.020530
AHNAK	-0.020509
FDXR	-0.020484
GPR153	-0.020462
JAG1	-0.020434
GNAZ	-0.020324
GDF3	0.020303
KAL1	0.020294
GEM	-0.020277
MBD5	-0.020257
YPEL1	-0.020253
TXN	0.020250
SLC4A8	-0.020249
THBS2	0.020206
TMEM2	-0.020196
NLGN4X	0.020106
ITPR2	0.020091
ROR2	-0.020088
FZD5	-0.020056
WIF1	0.020020
IL12RB2	-0.020016
PRSS23	-0.020014
NFE2L3	0.020006
CTNND2	-0.019988
MPP6	0.019956
MPHOSPH9	-0.019952
ADCY6	-0.019931
FBXO22	-0.019882
ELK3	0.019871
NLRX1	-0.019822
BCL2L11	-0.019771
SLC35A1	-0.019751
P2RY1	0.019682
ABHD4	0.019669
SPIB	0.019636
SLC6A8	-0.019624
ITGB1BP1	-0.019565
KCNMB1	0.019553
RND2	-0.019546
PAN2	-0.019531
GJC1	0.019495
NEBL	-0.019457
TAC3	-0.019454
HIST1H2BJ	0.019381
MMP2	0.019374
FERMT2	-0.019373
SYNJ2	0.019319
BNIP3	-0.019305
GNG12	0.019298
AOX1	-0.019266
ATP1B1	0.019228
MTHFSD	-0.019227
CRABP2	-0.019217
LAMB1	-0.019196
PDE6B	-0.019188
ADCY2	0.019181
CDK5RAP3	-0.019114
EFR3A	0.019106
GNG4	0.019102
LEF1	-0.019099
ARL4C	-0.019089
RIPK4	-0.019088
ROBO1	-0.019083
ZNF813	0.019079
NME5	-0.019047
ATP2B4	-0.019007
SEPP1	0.019004
GTF2H5	-0.018989
PPP3CA	0.018930
DOCK3	-0.018928
TRHDE	-0.018917
LPPR4	0.018909
NRCAM	-0.018873
AP3M2	-0.018869
RORA	-0.018849
GSTM1	-0.018833
MTL5	-0.018827
RBM19	0.018791
FAM69A	-0.018762
ZMAT3	-0.018751
CACNA2D2	-0.018747
LCK	0.018742
CITED2	-0.018740
PTPN20B	-0.018740
TNFRSF10C	-0.018721
CA4	-0.018719
MYOZ1	-0.018717
ZNF322P1	-0.018695
PIGF	-0.018687
GMCL1	-0.018665
IL2RB	0.018645
WSB1	-0.018634
HPGD	0.018632
NACAD	-0.018627
LITAF	-0.018594
H1F0	-0.018563
GABRA3	0.018500
SLC25A12	0.018475
THNSL1	-0.018472
NAGPA	0.018430
SLC12A1	0.018428
VASH2	0.018394
ZSCAN18	-0.018387
BEX1	0.018374
TRAPPC6A	-0.018364
SERPINE2	0.018334
WDR33	-0.018328
AASS	-0.018327
RBL1	-0.018267
TMEFF1	-0.018265
MAGI1	-0.018263