!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Mesalazine
!smiles	C1=CC(=C(C=C1N)C(=O)O)O
!drugbank_id	DB00244
!pubchem_cid	4075
!cell_type	colon
!organism	human
!end_metadata
UGT2B17	0.125499
FOSB	-0.077693
INSL5	-0.077618
RPS4Y1	0.073597
CRIP1	-0.064011
GHR	-0.062883
CD177	-0.061650
FAM3B	0.059688
TMEM200A	-0.058444
REG1B	0.057723
ATF3	-0.057625
SLC6A14	0.057460
GBP3	-0.056906
CYP2S1	-0.055968
PTPRR	-0.053768
GREM1	-0.052742
BAMBI	-0.052139
EPHA2	-0.051400
FLVCR1-AS1	-0.051020
CTGF	-0.050975
PPP1R14A	-0.050083
SSUH2	-0.049686
AQP11	-0.049241
HSD3B2	-0.048747
DMBT1	0.047665
HMOX1	-0.046984
C4BPA	0.046322
DUOX2	0.046281
PPP1R15A	-0.046046
RHOU	-0.046016
MCOLN2	-0.045882
CCL8	0.045446
TMED6	-0.044740
SVOPL	-0.043730
EIF1AY	0.043672
SERTAD3	-0.043040
TMEM220	-0.042908
ERAP2	-0.042817
BCO1	-0.042790
HSPB3	-0.042646
SECTM1	-0.042409
MMP3	0.042141
BTNL8	-0.041699
BTG2	-0.041541
HIST2H2BE	-0.040844
EYA2	0.040830
MYL9	-0.040547
TRPM6	-0.040517
NR1D2	0.040514
DUSP5	-0.040489
CDKN2B-AS1	-0.040466
ZFP36	-0.039542
CD14	-0.039378
HOXB13	-0.039334
PYY	-0.039005
SMIM6	-0.038927
REG1A	0.038562
PRAP1	-0.038506
ABCB1	-0.038265
FOS	-0.038006
CYP1A1	-0.037807
RARRES3	-0.037753
UGT2B15	0.037660
CTSE	-0.037480
NAALADL1	-0.037361
KDM5D	0.037306
TMEM140	-0.037275
CCL11	0.037192
CYP3A4	-0.037158
TCL1A	0.037117
LOC100190986	0.037062
CSRNP1	-0.036906
HIST1H2BC	-0.036667
CLDN8	-0.036635
LOC100134445	0.036553
SNHG5	0.036361
LGALS2	-0.036242
MAFF	-0.035997
CXCL8	-0.035963
L1TD1	0.035860
SERPINA3	0.035768
TUBB2A	-0.035664
ADM	-0.035459
SLC46A1	-0.035367
CLEC3B	-0.035300
TMEM37	-0.035229
GZMK	-0.035198
TLR3	-0.035148
USF1	0.035136
NPTX2	0.034999
CCL18	-0.034987
DNAJC3	0.034952
NQO1	-0.034889
PRSS23	-0.034611
ABCG2	-0.034558
PDZK1	-0.034150
MOSPD1	-0.034133
CDKN2B	-0.034123
HAVCR1	-0.034121
PIM1	-0.034051
FZD7	-0.034010
PRAC1	-0.033950
DPP4	-0.033919
DUSP1	-0.033909
F13A1	-0.033781
SLC22A4	-0.033647
SMIM5	-0.033641
PADI2	-0.033564
ABCC6P1	-0.033548
TFPI2	0.033464
NUF2	0.033195
HBB	-0.033137
FAM83D	0.033105
LINC00483	-0.033068
TRIM58	0.032996
EDN3	-0.032891
RHOBTB1	-0.032860
JUND	-0.032858
LYZ	-0.032800
HKDC1	-0.032743
MT1M	-0.032703
GREM2	-0.032629
CYR61	-0.032615
CHST5	-0.032411
DDX60	-0.032375
TLDC2	-0.032175
HLA-DQB1	0.032083
NR4A2	-0.032079
CBX5	0.031995
TNFRSF1B	-0.031931
HIST1H1C	-0.031920
SCNN1B	-0.031829
PSRC1	0.031729
BDKRB1	-0.031708
HIST1H3E	-0.031661
PCK1	-0.031661
GCOM1	-0.031497
CTHRC1	0.031431
CAPN13	-0.031397
TARP	0.031378
TXLNGY	0.031339
BCHE	-0.031290
SLC1A1	-0.031261
VLDLR	-0.031224
ARNTL	-0.031185
GPRIN2	-0.031161
RIPK4	-0.031109
SLC30A10	-0.030969
AXDND1	0.030928
S100P	-0.030891
NLRP2	-0.030887
SPAG4	0.030881
NTN4	-0.030849
FAM86B1	0.030619
TNIP3	0.030530
CD38	0.030506
ANKRD22	0.030482
CPT1A	-0.030452
RPP40	0.030233
NPAS2	-0.030205
IGFBP3	-0.030108
TTC22	-0.030076
RGS2	-0.030041
CENPE	0.029987
CLC	-0.029955
OAS1	-0.029904
LINC01268	-0.029804
SCGN	-0.029626
NDN	-0.029501
C21orf88	-0.029463
EPDR1	-0.029282
CA4	-0.029156
CNKSR3	-0.029100
KIF18B	0.029083
MAX	-0.028988
GPR128	-0.028834
VNN1	-0.028778
ZNF879	0.028753
CXCL10	-0.028733
SRD5A3	0.028710
KCTD4	-0.028597
HSD17B2	-0.028528
CECR1	0.028469
PDK4	-0.028462
ARG2	0.028461
RHOF	-0.028232
DUSP2	-0.028221
NR4A1	-0.028180
OLFML3	-0.028139
RASSF2	-0.028125
NKG7	-0.028117
ATG14	-0.028107
JUNB	-0.028096
TRMT2B	-0.028053
KLF10	-0.028049
PSPH	0.028024
FOSL1	-0.027978
TPX2	0.027917
CLCA1	0.027912
TOB1	-0.027681
BTNL3	-0.027647
EMC9	0.027624
DLGAP5	0.027479
TNFRSF17	0.027413
CYP27A1	-0.027403
SHCBP1	0.027395
OTC	0.027379
ZNF383	0.027377
MZB1	0.027360
SLC35G1	-0.027316
CDHR2	-0.027302
OCEL1	-0.027283
XIST	-0.027278
EEF2K	-0.027271
GAA	-0.027217
CH25H	-0.027188
HLA-DRB4	-0.027159
MEIS3P1	0.027152
EGR1	-0.027039
MYBL2	0.027019
AOC3	-0.026990
GUCA2B	-0.026905
C19orf33	-0.026869
SLC6A19	-0.026860
TMEM35	-0.026848
ABHD12	-0.026730
IGFBP6	-0.026697
RASSF10	-0.026688
NMU	0.026682
RBP2	-0.026679
IL2RG	-0.026632
LPCAT1	0.026629
CCDC146	-0.026552
MGMT	0.026472
ASPN	-0.026444
HMGCS2	-0.026418
CYP1B1	-0.026362
ACP5	-0.026274
PRKG2	-0.026251
MANF	0.026215
MST1L	0.026201
ENPEP	0.026193
SLC25A20	-0.026163
C1orf210	-0.026114
PDK2	-0.026081
TRIM59	0.026079
TRHDE	-0.026066
SLC20A1	0.026044
CXCL11	-0.025998
LGMN	-0.025977
AQP7	-0.025976
SGK223	-0.025947
FN1	-0.025941
ITGA2	0.025938
NFIL3	-0.025839
CXCR4	-0.025817
FKBP5	0.025670
NEAT1	0.025639
CHRDL1	-0.025586
ZNF674-AS1	-0.025547
CYP4X1	0.025529
RND1	-0.025499
SIK1	-0.025492
LOC145837	-0.025451
VEGFA	-0.025406
HMMR	0.025350
TINAGL1	-0.025331
C17orf97	-0.025272
GSPT2	0.025271
LINC00960	0.025252
APOBEC3A	-0.025198
SHROOM2	-0.025178
CCDC58	0.025161
SLC22A5	-0.025131
FAM150B	-0.025098
PAG1	-0.025075
LINC00540	0.025059
PARP12	-0.025029
FLNA	-0.025020
RAI14	-0.024979
FAM57A	0.024937
SLC25A37	0.024922
NDC80	0.024905
ENTPD7	0.024826
DEFB4A	0.024789
NCAPG	0.024757
IL32	-0.024745
OPHN1	0.024733
LAX1	0.024682
HIST1H2BE	-0.024591
TAGLN	-0.024563
ST6GALNAC3	-0.024529
MMP12	-0.024473
TEKT4P2	-0.024460
BCL2A1	-0.024436
LRP4	-0.024425
TULP4	0.024420
MIR21	0.024413
HSPH1	0.024324
PILRB	-0.024255
APOBEC1	0.024159
NHEJ1	-0.024141
H2BFS	-0.024133
SLC19A3	-0.024123
RRM2	0.024118
MALAT1	0.024117
ZFYVE26	-0.024113
C4BPB	0.024099
SST	-0.024066
ACSL1	-0.023987
KMT2E	0.023977
TICAM1	-0.023970
HIST1H3H	-0.023952
LTF	0.023899
PRPF38B	0.023819
ADRA2A	0.023738
RIMKLA	-0.023736
RPL10L	-0.023711
EFEMP1	-0.023708
CCL20	0.023693
DUOXA2	0.023671
HHLA2	-0.023652
IL1B	-0.023632
TGFBR3	-0.023543
CHAC2	0.023499
IGLV1-36	0.023485
TCN2	-0.023484
TIMP2	-0.023460
P2RY2	-0.023414
RAB3B	-0.023364
PDK3	0.023338
MMP1	0.023325
IER2	-0.023295
FICD	0.023292
MELK	0.023290
HMGB3P1	0.023287
CD69	-0.023268
GZMB	-0.023245
ISG15	-0.023218
CCNJL	-0.023165
NPY4R	-0.023132
C10orf2	0.023130
MYH11	-0.023125
MS4A1	0.023076
AMOTL2	-0.023026
LGALSL	-0.022974
ADH1C	0.022929
MKI67	0.022929
SLC28A2	-0.022924
PMM1	-0.022923
TAC1	-0.022878
CEP55	0.022865
PPCDC	-0.022854
IL7R	0.022851
CRELD2	0.022851
HBEGF	-0.022850
NDRG1	-0.022789
NEURL1B	-0.022751
CPNE5	-0.022732
NTS	0.022674
KIF20A	0.022667
KLHL13	-0.022659
EPHX1	-0.022641
GAS2L3	0.022635
LINC00115	-0.022631
CYP4F2	-0.022631
ZNF14	0.022601
CCNA2	0.022572
VSIG4	-0.022556
PRUNE2	0.022540
DEFA5	0.022540
FBXO32	-0.022500
BUB1B	0.022498
SPSB2	-0.022452
PEX26	-0.022437
SLC5A11	-0.022437
SLC7A7	-0.022423
B4GALNT2	0.022404
NCF4	-0.022393
IL15RA	-0.022390
MMP28	-0.022371
C10orf54	-0.022346
EGLN3	-0.022327
FCAMR	0.022318
PRSS8	-0.022279
COL4A3BP	0.022227
CDC6	0.022200
BRI3	-0.022189
PLAGL2	-0.022166
HIST1H2BD	-0.022123
SDF2L1	0.022103
BHLHE40	-0.022100
ZBTB25	-0.022093
PPP1R14C	0.022064
LCN2	0.022050
PRC1	0.022040
SGK1	-0.022035
STAP1	0.022013
SFTPA2	0.022001
NR1H4	0.021962
SH2B2	0.021956
CNN1	-0.021950
C8orf33	-0.021945
IRF6	-0.021922
HPGD	-0.021921
MAP1LC3B	-0.021909
AMACR	-0.021908
CXCL16	-0.021867
AMFR	0.021851
PBK	0.021831
GABRA2	-0.021782
ATF7IP2	0.021764
AOAH	-0.021760
CASP5	0.021745
HIST1H2BH	-0.021732
FAM110C	-0.021717
RSAD2	-0.021699
KLK1	-0.021666
IGLV3-19	0.021630
SLC36A4	0.021609
MUC12	-0.021604
P2RY1	-0.021603
PPAP2A	-0.021568
RBM24	-0.021565
CTH	-0.021545
ASB13	-0.021542
LINC01123	-0.021530
HINFP	-0.021515
APOL1	-0.021504
CCDC86	0.021460
KIF15	0.021449
CTPS1	0.021441
GADD45A	-0.021365
S100A4	-0.021350
CFI	0.021349
RALGDS	-0.021312
SGK2	-0.021306
CIPC	-0.021300
HCAR3	0.021280
USP30-AS1	-0.021270
CD163L1	-0.021265
TM4SF20	0.021242
C2orf54	-0.021239
IGLJ3	0.021210
UHMK1	0.021169
MTMR3	-0.021155
CDCA5	0.021143
C11orf96	-0.021132
C9orf24	-0.021129
HSBP1L1	-0.021111
COL17A1	-0.021109
PCSK9	0.021084
C1orf116	-0.021079
TPSB2	0.021071
C3	-0.021071
FGF13	-0.021066
CDK1	0.021055
RASA2	0.021050
FOXF2	-0.021024
EP300-AS1	0.021007
ZFY	0.020998
PI15	-0.020997
ILF3-AS1	-0.020918
LEPREL1	0.020915
RRS1	0.020895
ZBTB8A	0.020891
IL13RA2	-0.020862
PLA2G7	-0.020857
SPIB	-0.020852
CREB1	0.020827
NOP58	0.020824
FAM198B	-0.020810
GJA1	0.020809
MMP10	0.020785
MYO15B	-0.020780
PPAT	0.020776
B3GNT5	-0.020761
FOXA1	0.020708
CLEC10A	-0.020706
VIP	-0.020692
ZSCAN26	0.020683
SPRYD7	-0.020676
MT1F	-0.020675
C14orf93	-0.020649
HIST1H2AC	-0.020633
SPC25	0.020625
HIST1H2AE	-0.020600
STAT4	0.020596
PIK3R1	0.020581
CKAP2L	0.020532
LINC01082	-0.020494
SLC25A34	-0.020475
WBSCR27	-0.020467
CIRH1A	0.020444
BDKRB2	-0.020438
PDCD4	-0.020423
RAB17	-0.020405
SCGB2A1	-0.020376
NEU1	-0.020366
SOWAHA	-0.020359