!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!cell	Kidney
!perturbation	Ibuprofen  263 mg/kg - 3 d - Male
!end_metadata
ALB	-0.186568
HMGCS2	0.114292
PCDH9	-0.103844
VNN1	0.098234
IGFBP1	0.096769
TMEM252	0.094728
ANGPTL4	0.092480
A2M	0.091598
FOSB	0.089097
S100A9	0.087074
LCN2	0.084627
AHSG	-0.077895
LAMC2	0.076181
FAM111A	0.068246
RESP18	0.066074
TTR	-0.065095
CCL13	-0.064853
MRAP	-0.064573
ATF3	0.064411
RARRES2	0.062812
EPO	0.061098
SLC25A25	0.061061
SNCA	-0.060063
NR1D1	0.058513
ADH1C	0.058300
SPP1	0.057810
GUCA2A	0.057769
FKBP5	0.057217
MATN1	0.056982
THRSP	-0.056541
SCD	-0.055340
CP	0.054867
BTG2	0.054171
TIMP1	0.053958
FADS1	-0.053197
CA3	-0.052720
MYC	0.051801
LOX	0.051692
DUSP5	0.051279
MAB21L3	0.049275
KRT19	-0.049002
FASN	-0.048909
PLA1A	0.048866
GPNMB	0.047678
FABP1	-0.047365
PDK4	0.047198
INHBB	0.046410
S100A8	0.046271
PSPH	-0.046075
DMBT1	0.045994
DDIT4	0.045553
PAMR1	-0.045420
EHHADH	0.045051
ITIH3	-0.044399
ATG10	0.043680
UBD	0.042896
STEAP4	0.042029
GDA	0.041816
ALOX15	0.041747
SEMA4B	0.041694
RASD1	0.041665
GADD45B	0.040450
HMGCS1	-0.040406
C3	-0.040276
STEAP1	0.039937
CYP27B1	0.039802
SERPINE1	0.039649
CXCL13	-0.039617
HP	-0.039610
TGIF1	0.039516
HPX	-0.039282
UCP1	-0.039070
MAFF	0.038892
CEBPB	0.038885
TRIL	-0.038769
CDKN1A	0.038559
FAM103A1	-0.038383
ZNF367	-0.038329
CYP2E1	0.038232
MRC1	0.038226
SERPINE2	-0.038222
PSMG3	0.038131
TSPAN8	0.037833
NPAS2	-0.037771
NFKBIA	0.037745
CCRN4L	0.037311
SPTA1	-0.037228
IGF1	-0.037197
DIO1	-0.036973
PPP1R1B	-0.036933
PER1	0.036811
RAMP3	0.036591
CCNG1	0.036509
ANGPTL2	-0.036505
MIS18A	0.036437
TCF19	-0.036387
EGR1	0.036343
FGG	-0.036252
TACSTD2	-0.035974
CLEC10A	0.035532
CLDN4	0.035214
PCSK6	-0.035140
COTL1	-0.035079
NR4A3	0.034960
BAALC	0.034868
DECR1	0.034555
DBP	0.034471
CRYGA	0.034437
BIRC3	0.034418
PHACTR1	-0.034230
GCGR	-0.034197
COL9A1	-0.034168
JAG1	-0.034147
BEX4	0.034125
PLG	-0.034062
HIST1H2BJ	-0.034025
SDS	0.033899
CMC1	-0.033892
MARC1	0.033888
ACE	0.033777
ARNTL	-0.033603
KLKB1	0.033548
CPT1A	0.033488
IER3	0.033350
PGM5	0.033323
BUB1	-0.033275
ITIH4	-0.032757
GAL	-0.032685
RPRM	0.032656
C1QC	0.032634
ACAA2	0.032610
CACNG5	-0.032556
C1QB	0.032524
PLK2	0.032495
GPX2	0.032457
ECH1	0.032451
LACTB2	-0.032415
TNFRSF12A	0.032155
SLC34A2	0.032112
CXCL14	0.031950
GRAMD1B	0.031877
SLC28A2	0.031848
NR1D2	0.031507
LRP4	0.031469
KCNK5	0.031419
FRZB	0.031416
TESC	-0.031258
LRAT	0.031043
KCNJ12	-0.030994
KCTD1	0.030929
KIF20B	-0.030726
ESM1	-0.030724
LDHA	0.030662
TNFRSF11B	-0.030604
IDI1	-0.030565
IGSF10	-0.030478
TEX101	-0.030327
SPRR1A	-0.030296
IMPA2	0.030241
DPT	-0.030107
PROCR	0.029720
CYP51A1	-0.029709
CPS1	-0.029681
SOSTDC1	-0.029677
ANPEP	-0.029677
ELF3	0.029637
ADA	-0.029481
OSBPL3	0.029303
MGMT	0.029189
PEX11A	0.029154
SMC2	-0.029092
ARL4A	0.029029
PDP2	-0.028986
MFAP4	-0.028815
PPARD	-0.028732
CCNA2	-0.028639
PBK	-0.028588
RUNX1	0.028497
ANKRD37	0.028478
MKI67	-0.028315
GC	-0.028229
APOA1	-0.028119
BHLHE40	0.028071
NDRG4	0.027928
SPC25	-0.027920
PTGS2	0.027918
LSS	-0.027730
VMP1	0.027664
PHLDA2	-0.027542
RNF6	0.027472
FAT3	-0.027451
C1QA	0.027427
RRM2	-0.027282
MALL	0.027280
TRIM59	-0.027278
JAM2	0.027245
TIMELESS	-0.027209
MSMO1	-0.027206
SLC6A6	0.027167
LRG1	0.027098
ERRFI1	0.027076
KRT8	0.027041
DBR1	-0.026918
LRIF1	-0.026791
ASNS	0.026683
MELK	-0.026609
ECHDC3	-0.026579
TNFRSF21	0.026462
CREB3L3	0.026420
APOBEC1	0.026347
SLC51A	-0.026304
ACTG2	-0.026298
NR0B2	-0.026277
PDE4DIP	-0.026241
AQP2	-0.026009
SKAP2	-0.025905
MEDAG	0.025840
ART3	0.025808
AADAC	-0.025730
INSIG1	-0.025708
DGUOK	-0.025646
VPS13C	0.025641
SLC16A7	-0.025577
CPNE8	0.025483
STYXL1	0.025471
CLU	0.025417
ARRDC4	0.025407
AVPR2	-0.025373
ACACA	-0.025370
CNR1	-0.025317
HSD17B2	0.025284
CPED1	0.025223
KRT18	0.025185
WFDC2	0.025174
AMBP	-0.025004
APLN	-0.024985
PTPRJ	0.024979
IER5L	0.024930
KCNS3	0.024917
CCL20	0.024791
EGFL6	-0.024771
VWF	0.024713
CEBPD	0.024643
TMEM144	-0.024609
UPP1	0.024598
AMOTL2	-0.024575
ITGB6	0.024556
SOD3	0.024502
TTC21B	0.024490
HSPA12A	-0.024454
ALX1	0.024441
COL15A1	-0.024380
HSD3B2	0.024324
PVR	0.024312
UPK3A	-0.024265
COL1A1	-0.024257
POLA1	-0.024250
DHX9	-0.024226
FAM151A	-0.024222
LRRC8B	-0.024060
CALB1	-0.024043
SCIN	0.024034
IFRD1	0.024032
SMPX	-0.024002
LILRB4	0.023967
SDF2L1	-0.023960
PXMP4	0.023923
MCOLN2	-0.023892
FANCL	-0.023887
VEGFB	-0.023841
SLC17A3	-0.023794
UPK1B	-0.023792
SLC2A4	-0.023778
BHMT	0.023735
CDKN3	-0.023674
IL1B	-0.023655
KIF11	0.023613
ARG1	-0.023603
DDX19A	-0.023561
ECI2	0.023525
ISG20	0.023519
LAMA1	0.023344
ASGR1	0.023329
SLC41A3	0.023314
USP2	0.023309
NEK6	0.023265
BCL6	-0.023235
GABRP	0.023225
KLF11	0.023204
TXNIP	0.023156
MAMDC2	-0.023130
ZFP36	0.023090
SCHIP1	-0.023088
PDE10A	0.023023
TOR3A	0.022993
FBXO32	0.022965
ADRA2A	0.022864
TUBA4A	-0.022817
NOX4	-0.022782
SULT1E1	-0.022729
ARL4D	0.022688
MMP9	-0.022677
GLIPR1	0.022607
SCARB2	0.022599
CTGF	0.022598
SULT1C2	-0.022584
CRY1	-0.022519
HAO1	-0.022513
CTSS	0.022495
ADAMTS4	0.022493
NETO2	-0.022468
G6PC	0.022468
ABCC8	-0.022442
HSD17B1	-0.022431
SLC4A1	-0.022424
FEN1	-0.022381
PPL	0.022264
LOC102723475	-0.022191
CRP	-0.022150
PIGR	0.022143
CDK1	-0.022138
SLC43A1	0.022089
CLEC11A	-0.021989
SERPINA3	-0.021938
APLNR	-0.021874
SREBF1	-0.021832
RIN2	0.021825
RIBC1	0.021712
ECI1	0.021700
NRIP3	-0.021687
IL6ST	0.021678
PENK	0.021636
GSTM2	-0.021586
CCDC64	0.021571
USP46	-0.021541
FGL2	0.021510
CLDN3	0.021478
GPAM	-0.021428
NRN1L	-0.021417
MYL9	-0.021407
GPR137B	-0.021376
CSRP2	0.021353
TNFRSF1A	0.021324
MCM6	-0.021315
CTHRC1	0.021292
CSRNP1	0.021273
TINAG	-0.021262
SQLE	-0.021240
ASPN	-0.021223
CYP26B1	0.021077
SLC22A7	0.020993
IL6	0.020975
GAS2	-0.020938
LEO1	-0.020909
DNAJA4	-0.020897
CYP2S1	0.020894
PRC1	-0.020881
NME7	-0.020873
PTPRQ	-0.020839
SAT1	0.020814
JUNB	0.020778
RBP4	-0.020769
CCDC141	-0.020732
CXCR4	0.020593
SMIM5	-0.020550
SDPR	-0.020541
KIF22	-0.020527
FAM115C	0.020513
IER2	0.020494
ANXA6	-0.020459
HMGCL	0.020449
SESN2	0.020394
CD44	0.020391
RDH16	-0.020385
TRPV1	-0.020337
RARRES1	-0.020329
STAT3	0.020299
ZFP14	-0.020285
LYRM7	-0.020241
MGP	0.020231
ISPD	-0.020174
VTCN1	0.020163
WIPI2	0.020149
ACMSD	-0.020134
CYGB	0.020128
LBP	0.020107
RGN	-0.020065
HEY2	-0.020013
GALNT11	-0.019982
GFRA4	0.019952
ASPM	-0.019950
GLTSCR2	0.019936
ANXA1	0.019925
HMGCR	-0.019904
HERPUD1	0.019865
WNT5B	0.019857
BDH1	-0.019855
PAPSS1	-0.019854
TEF	0.019853
DNAJC6	-0.019813
TFDP1	-0.019745
SPICE1	0.019728
SMTN	-0.019725
CEMIP	0.019721
DFNB59	-0.019711
AEN	0.019693
NINJ2	0.019686
PLD1	0.019680
SLC16A6	-0.019674
SKA1	-0.019671
RAD51	-0.019618
MAP2K6	-0.019608
SLC44A4	0.019595
TSPAN1	0.019575
CDCA3	-0.019563
TSKU	-0.019559
SCRN1	0.019556
PPCS	0.019540
SEMA6A	0.019506
MIS12	-0.019490
PAFAH1B3	0.019471
CTSF	0.019469
CSGALNACT1	-0.019435
TMEM204	-0.019429
MPPED2	-0.019415
CYFIP2	-0.019406
RGS4	0.019405
ABCC3	0.019394
ZAK	0.019389
MLPH	0.019364
CIRBP	0.019339
CPT2	0.019320
CRYL1	-0.019307
ACER2	0.019287
REXO4	-0.019243
ITGB4	0.019228
TPRKB	-0.019209
ECT2	-0.019207
GJA1	0.019203
CYP20A1	-0.019199
GLRX	0.019190
TRIM37	-0.019148
ACOT2	0.019067
CD14	0.019021
ELL	0.019020
IRF6	0.018914
PLAU	0.018869
PDE1A	-0.018868
CLEC7A	0.018860
DMTN	-0.018825
CDA	0.018821
DLAT	-0.018799
MYPN	0.018773
PCDH18	-0.018768
POU2AF1	0.018762
TFPI2	0.018757
SLC6A12	-0.018757
WFDC1	-0.018714
S100A4	-0.018617
CLDN5	0.018608
ABHD3	0.018598
SLC27A5	0.018590
TUBB	-0.018583
FAM105A	0.018580
FHOD3	-0.018573
NAMPT	0.018567
FBLIM1	0.018523
SPP2	-0.018502
TIGD3	-0.018488
DMXL2	-0.018463
SNTA1	-0.018460
PIK3R1	0.018437
MAP3K8	0.018422
FOSL2	0.018414
KLF10	0.018399
HNF1B	-0.018398
SSFA2	0.018397
SLC13A1	0.018384
MMP15	-0.018366
COMT	-0.018343
RPP25	-0.018333
CFI	0.018330
BAAT	-0.018327
PDE9A	0.018325
KIFC1	-0.018318
LUM	-0.018314
FBN1	0.018305
GATSL3	0.018263
PTGES	0.018244
TSC22D3	0.018218
KANK4	-0.018156
APOH	-0.018142
DHFR	-0.018138
OSR2	-0.018131
F3	0.018101
FAM101B	-0.018092
E2F1	-0.018070
GNAI1	-0.018021
FKBP4	-0.018018
NOS3	0.017974