!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Leptin
!drugbank_id	DB05098
!cell_type	Gallbladders (from leptin-deficient obese females following daily treatment with 5 ug/g recombinant leptin for 4 weeks)
!organism	mouse
!end_metadata
SCD	-0.210418
APOA1	0.180826
SAA1	0.173712
LCN2	0.169617
PIGR	0.155767
IGJ	0.149602
CD74	0.144200
SGK1	-0.115843
LY6D	0.110429
SLC25A47	-0.107739
ALDOB	-0.105510
C3	0.093758
KRT8	-0.093232
THRSP	-0.093107
FABP1	0.092017
APOA4	-0.090991
ADH1C	-0.090005
REG1A	-0.085857
CTGF	-0.084285
HLA-DRB5	0.083497
MMP7	-0.083298
GAPDH	-0.082466
NDUFA4	-0.081017
PLIN2	-0.079071
HLA-DQA1	0.078619
SFTPD	0.078575
GNMT	-0.077799
TNFRSF12A	-0.076336
DMBT1	0.074450
HPX	0.072145
RETSAT	-0.068481
ACTG1	-0.068360
KRT18	-0.067802
HMGCS1	-0.066587
OLFM4	0.066215
IFITM3	0.066166
KRT19	-0.065486
LTF	0.065056
RNASE4	0.064833
EFHD2	-0.064281
CRIP1	-0.063109
CYP2F1	-0.062779
ALDH1A1	-0.062125
ANXA3	-0.061119
CXCL6	0.060994
AHCY	-0.060534
ITIH4	0.060479
PGRMC1	-0.059353
INSIG1	-0.058259
CTSS	0.058149
ANG	0.057440
ANGPTL3	-0.057363
FBP1	-0.057332
PDZK1IP1	0.057090
AQP1	0.054790
ACTG2	-0.054622
INSIG2	-0.054406
ELOVL2	0.053155
RPS23	0.052898
TMBIM6	-0.052810
B2M	0.052668
KHK	-0.052544
GCLC	-0.051611
ST3GAL4	-0.051226
KRT7	-0.051136
P4HB	-0.051063
EIF4A2	0.050611
STARD10	-0.049230
HSPB1	-0.048828
LGALS1	-0.047989
RPS12	0.047952
S100A6	-0.047536
CORO2A	-0.047524
REEP6	-0.047384
CSRP1	-0.047019
RPL10	0.046731
SLC2A2	-0.046603
ALB	0.046368
SERPINA1	0.046354
EPHX1	-0.046194
ANXA13	-0.044660
S100A10	-0.044583
TMEM176B	0.044566
CYP8B1	0.044366
TKT	-0.044353
IDH1	-0.044350
LPL	-0.044250
RPS5	0.044233
ACSL5	-0.044159
RGN	0.044112
PLET1	0.044051
FABP4	-0.043983
EHHADH	0.043314
LAD1	-0.042979
GSTA5	-0.042862
PGK1	-0.042723
COX7A2	-0.042237
FAM134B	-0.042121
PGLYRP1	0.042113
PSMB7	-0.042099
ALDH1L1	-0.042058
EGR1	-0.041705
ACTN4	-0.040267
GABRP	0.039805
HERPUD1	-0.039739
MAN2A1	-0.039726
EIF4A1	-0.039709
BNIP3	-0.039295
MAT1A	0.039248
CAV1	-0.039234
S100A8	0.039008
SLC25A5	-0.038912
XBP1	0.038738
DSTN	-0.038668
ACTR3	-0.038611
ASS1	-0.038611
GPX4	-0.038329
UGT2B10	-0.038214
HP	0.038110
TFF2	0.038061
HPRT1	-0.037855
SLC10A1	-0.037272
RPS29	0.037185
RPL26	0.037156
GLRX5	-0.037110
ADIPOQ	-0.037109
RPS28	0.037066
TTPA	-0.036813
AGPAT2	-0.036721
AKR1A1	-0.036624
TUBB2A	-0.036246
BGN	0.036010
FASN	-0.036002
LGALS2	-0.035952
GSTM5	-0.035855
GSTO1	0.035718
NME2	-0.035687
RPLP2	0.035536
TFF3	0.035305
C15orf48	0.035288
SELENBP1	-0.035284
LRG1	-0.035255
PDCD6	-0.035233
ASPA	-0.035179
SDHB	-0.034771
CBR3	0.034646
COL3A1	0.034415
SQLE	-0.034344
CIRBP	-0.034114
IDI1	-0.034048
APOA5	0.033603
MDH2	-0.033598
INMT	-0.033497
GLUD1	-0.033327
MGP	0.033229
TDO2	-0.032988
CYP1A2	0.032972
NDUFA8	-0.032957
MSMO1	-0.032760
HMGN1	-0.032740
HRSP12	-0.032728
WFDC2	-0.032547
CRP	0.032462
C11orf54	-0.032313
APOC4	-0.032166
TIMM23	-0.032055
GPT2	-0.032049
SAR1B	-0.031991
TUBA1B	-0.031448
ATP5G3	-0.031446
QDPR	-0.031421
RPS19	-0.031412
ASAH1	-0.031360
DGAT2	-0.031184
RPL38	-0.031047
PFN1	-0.031041
FGL1	0.030904
VNN1	0.030885
PLIN4	-0.030812
CCND1	-0.030759
TMEM30B	-0.030751
APOE	0.030741
APOC2	-0.030670
S100A9	0.030631
RHEB	-0.030194
IGFBP2	0.030152
RPL28	0.030078
ABCB1	-0.030074
SLCO2A1	-0.029965
EIF5A	-0.029959
TYROBP	0.029838
GPI	-0.029832
CYP2C8	-0.029767
CST3	-0.029695
ACADM	-0.029506
POSTN	0.029406
ISCU	-0.029124
GSTA3	-0.029106
CAPNS1	-0.029097
NDUFV2	-0.029083
CYBA	0.028871
SNX17	-0.028763
HSD17B10	-0.028727
PSMB4	-0.028694
UBALD2	-0.028595
MYL9	-0.028577
C1S	0.028552
SULT1E1	-0.028318
ATP5A1	-0.028316
FMO5	-0.028307
VDAC1	-0.028298
EZR	-0.028283
TUBA1A	-0.028171
CPS1	0.028120
GSN	-0.028065
SPP1	0.027852
DBI	-0.027812
COX6B1	-0.027781
UBE2D3	-0.027778
F3	-0.027778
EGLN2	-0.027768
ENPEP	-0.027717
CSF1R	0.027686
PLG	0.027671
COL4A1	-0.027605
FGA	0.027544
RPL3	0.027414
SERPINB1	-0.027407
LAMP1	-0.027383
GSTZ1	-0.027370
CNN1	-0.027342
ATP5B	-0.027303
ST3GAL5	-0.027281
SNX7	-0.027272
FOS	-0.027094
ECI2	-0.027093
S100G	0.027088
FKBP5	-0.027019
CHPT1	-0.026866
SLC25A24	-0.026835
SLC4A4	-0.026787
HSP90B1	0.026589
DUSP1	-0.026579
AMY2A	-0.026534
TTR	0.026454
MPZL2	-0.026396
ABCD3	-0.026390
LYZ	0.026374
AHSG	0.026297
CA2	-0.026194
ANO6	-0.026109
C1QA	0.025912
CDH1	-0.025757
DEGS2	-0.025728
RPL9	0.025719
CYC1	-0.025669
RNF149	-0.025451
CIDEC	-0.025443
CLDN7	-0.025392
UQCR11	-0.025362
AJUBA	-0.025291
MPC1	-0.025286
SORD	-0.025283
SLC27A2	0.025185
SLC35G1	-0.025097
SCNN1A	-0.025080
SCARB2	-0.025063
CEP85	0.024942
MFSD2A	-0.024897
SLC9A3R1	-0.024788
C1QBP	-0.024670
DPT	0.024661
CD14	0.024641
TECR	-0.024522
PEBP1	-0.024505
RPS11	0.024497
ATF5	0.024317
ACAT2	-0.024220
SERPINB6	-0.024209
LGALS4	-0.024028
SULT1C2	-0.024013
C9	-0.023974
PRDX1	0.023911
ZFP36L1	0.023705
EFEMP1	0.023673
ARHGEF5	-0.023660
CFL1	-0.023649
ACOX1	-0.023581
ONECUT2	0.023499
ZMPSTE24	-0.023345
ETFA	-0.023276
RPS24	0.023275
TBCB	-0.023211
RBM3	-0.023137
FGB	0.023130
HMGCS2	0.023088
FDPS	-0.023052
STARD4	-0.023026
MBOAT1	-0.023017
DAK	-0.022997
AKR1C4	0.022972
VCP	-0.022944
VDAC2	-0.022897
CCKAR	0.022885
APOB	-0.022874
PLAC8	0.022829
ZFP36	-0.022814
AZGP1	-0.022769
PPA1	-0.022742
HADH	-0.022715
MGAM	-0.022672
SLC27A5	-0.022606
CBR1	0.022583
HLA-DQB1	0.022508
CDKN1A	-0.022449
SLC37A4	-0.022354
PCBD1	-0.022320
PAMR1	0.022243
APRT	-0.022190
ECHS1	-0.022083
CSTB	-0.022064
PEX11A	-0.022051
DMGDH	-0.021939
UGP2	-0.021850
ATP6V0C	-0.021798
MYL12B	-0.021796
TSTD1	-0.021613
PAH	0.021590
H19	-0.021437
TOMM20	-0.021434
SCPEP1	0.021420
RPLP0	-0.021332
CLU	0.021315
NDUFS2	-0.021182
APOM	0.021093
GCHFR	-0.021088
RPL22	0.021054
TPT1	0.021018
PPP2CA	-0.020862
DAZAP2	-0.020839
CNBP	-0.020760
HAX1	0.020737
HNRNPA0	-0.020735
UBC	-0.020729
TMEM41A	-0.020720
MPEG1	0.020712
HSD17B12	-0.020672
CTNNA1	-0.020600
ATP1B1	-0.020542
ANXA2	-0.020499
EEF1A1	0.020453
FAM213A	-0.020429
MARC2	-0.020418
SERPINF2	0.020386
C1QC	0.020381
CEBPA	0.020174
CFH	0.020166
UGT2A3	-0.020157
SUCLG2	-0.020156
CYP2C9	-0.020123
IFRD1	-0.020102
RPS27L	-0.020098
PSMB5	-0.020092
ACAD11	-0.020086
SLC25A10	-0.020074
LEAP2	-0.020011
CISD1	-0.019984
RPS9	0.019966
LY6E	0.019914
YWHAZ	-0.019911
C8A	0.019858
RPS7	0.019714
GPX1	-0.019672
PYGL	-0.019672
FAT1	-0.019669
CCT6A	-0.019661
KCNK1	-0.019554
GABARAPL1	0.019511
MYO1A	-0.019484
SLC25A46	-0.019413
DDX17	0.019399
PPIA	-0.019390
GCSH	-0.019350
CTSD	-0.019342
AES	-0.019332
SLC38A4	-0.019331
ARPC2	-0.019330
GORASP2	-0.019297
ERRFI1	-0.019261
CERS2	-0.019237
SPINK4	0.019221
CNIH1	-0.019208
HADHA	-0.019175
CD36	-0.019145
PON1	0.019119
PHLDB2	-0.019098
NUDT4	-0.019090
ACAA2	-0.018953
ALOX5AP	0.018925
TCP1	-0.018895
MGST3	-0.018856
GSTM1	-0.018668
EIF6	-0.018647
RPS8	-0.018640
MYC	-0.018518
SMOC1	-0.018462
G0S2	0.018451
PSAP	0.018436
AKR1D1	-0.018430
CYB5B	-0.018424
CA9	-0.018420
PCNA	-0.018415
CDO1	-0.018396
NDUFB7	-0.018381
CMPK1	-0.018348
NFKBIA	0.018289
DDX3X	-0.018260
TMEM45B	-0.018204
CDIPT	-0.018172
EI24	-0.018169
ALDOA	-0.018137
CTRB2	-0.018078
LGALS3BP	-0.018069
PSMD14	-0.018062
ARHGDIA	-0.018045
ASGR1	-0.018021
ACO2	-0.018018
MYO18A	-0.018000
NSUN2	-0.017973
PISD	0.017937
NDUFS3	-0.017920
EPS8L2	-0.017913
SLC44A3	-0.017889
ITGB8	-0.017873
CDCP1	-0.017844
RPL11	-0.017795
BHLHE40	-0.017781
LBR	-0.017750
CHMP2B	-0.017672
LRRC59	-0.017634
DCN	0.017510
NIPSNAP1	-0.017460
FKBP8	-0.017426
PAQR9	0.017345
SLC25A4	-0.017278
FLNA	-0.017195
S100A1	-0.017179
PDHA1	-0.017176
AGXT	0.017174
CYP51A1	-0.017127
RHOU	-0.017104
SFXN1	-0.017091
EIF3B	-0.017050
HSPA8	0.016994
KLHL9	0.016976
PPIB	-0.016957
CCT2	-0.016931
PPTC7	-0.016927
RPL18A	0.016899
LITAF	-0.016856
CYP7A1	0.016835
CYP4B1	-0.016731
CLPTM1L	-0.016727
ALDH6A1	-0.016675
ATP5F1	-0.016647
YWHAE	-0.016629
PGAM1	-0.016617
NDUFS6	-0.016557
TP53INP1	-0.016542
ARG1	0.016512
ME1	-0.016506
PLTP	0.016489
PPP1R3B	-0.016435
PRDX3	-0.016393
NLRP6	0.016382
SPARC	-0.016347
ALAD	-0.016299
MRC1	0.016287
MSRA	-0.016271
SLC25A3	-0.016255
GC	-0.016243
RPL8	-0.016224
RAB5A	-0.016223
SHISA5	0.016191
DDB1	-0.016189
CEP170B	-0.016181
DDIT4	-0.016173
C14orf2	-0.016161
SEPP1	0.016106
PLIN5	-0.016087
FKBP1A	-0.015964
PERP	-0.015964
MAPK3	-0.015919
HSD17B4	-0.015884
VTN	0.015873
ACLY	-0.015862
LASP1	-0.015848
HSD3B7	0.015840
ATP1A1	-0.015829
SCAND1	-0.015764