!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	MCF-7 breast cancer cells
!organism	human
!end_metadata
EGR3	0.131035
GEM	0.094955
IGFBP4	0.082743
CYP1A1	-0.082277
PGR	0.080441
PDZK1	0.079255
KCNK6	0.078097
DOK7	0.075105
RASGRP1	0.072567
RAPGEFL1	0.071912
IL20	0.071353
SGK3	0.071155
SGK1	0.067477
NPY1R	0.066195
AGR3	0.065560
RHOBTB1	0.064763
NMRK1	0.064218
DRD1	-0.062939
RBM24	0.062095
FRK	0.062039
JAK2	0.061793
PREX1	0.060353
PGLYRP2	0.060143
SLC22A5	0.059471
CXCL12	0.058266
RAB31	0.055133
CA2	0.054378
ARHGAP36	0.054247
C8orf46	0.054103
TMEM164	0.053765
CAV1	0.053627
FHL2	0.053363
TNFSF10	-0.053129
HAUS1	0.052737
SGK223	0.052108
C14orf182	0.051725
PLEKHH1	0.051190
TNFRSF11B	-0.050944
C1orf226	0.050717
LONRF2	0.050090
SYBU	0.049249
TMA16	0.049219
SFXN2	0.046970
HS3ST3A1	0.046770
FFAR2	-0.046753
PMAIP1	0.046512
PTGES	0.046236
C6orf141	0.045037
LOC100506870	0.044972
RBBP8	0.044958
ARMCX6	0.044333
SMTNL2	0.044051
SYTL5	0.043854
ELOVL2	0.043337
GJA1	0.042612
SLC26A2	0.042110
MSMB	0.041791
C3orf70	0.041484
PITPNC1	0.041441
ERC2	-0.041391
CTR9	0.041217
HSPB8	0.041209
RUNDC3B	-0.040683
SVIL	0.040519
TMED8	0.039986
NRIP1	0.039794
AREG	0.039743
SCNN1B	0.039577
RET	0.039482
PCDH8	-0.039064
ARMCX3	0.038398
TPBG	0.038328
ZNF185	0.038079
WFS1	0.037747
MREG	0.037675
CCDC83	-0.037528
MGP	0.037449
LOC257396	0.037432
SLC1A1	0.037190
CXXC5	0.037150
GALNT4	0.037118
LINC00341	0.037100
CHSY1	0.036900
OTUD6B	0.036889
ARMCX1	0.036803
KIT	0.036703
TIPARP	0.036513
PLOD2	0.036284
FOXC1	0.036096
PKIB	0.036057
RLN2	0.035814
RFPL1S	0.034973
C1QTNF6	0.034884
ITGA2	0.034712
MYBL1	0.034699
TGIF2	0.034636
DEPTOR	0.034349
ULK1	0.034271
MYB	0.034159
IL6ST	0.034026
GHR	-0.033938
FAM189A2	0.033852
ABHD2	0.033831
TRIB2	-0.033671
DDIT4	-0.033651
MICB	0.033641
RASA4	-0.033510
BTG2	-0.033454
ASB13	0.033326
SACS	0.033131
PRRG1	0.032653
FOS	0.032514
NECAB1	0.032384
GRB14	-0.032256
ST8SIA4	-0.032106
HHEX	-0.032067
ZNF711	0.031904
SRSF5	-0.031890
SLITRK6	-0.031888
TMEM64	0.031850
RAI14	0.031543
FOXN1	0.031265
SOX11	-0.031254
PHF23	0.031233
DLG5	0.031232
EHHADH	0.031068
CEBPB	0.030958
CDKN2B	-0.030899
TIFA	0.030740
CELSR2	0.030707
EFCAB7	0.030596
ARMCX2	0.030491
SATB2	0.030470
CALCR	0.030354
KITLG	-0.030303
PKDCC	0.030074
SLC38A2	0.029899
NAF1	0.029834
PFKFB3	0.029614
TARP	-0.029593
KLF10	0.029580
SIAH2	0.029576
SGCG	-0.029551
FLNB	0.029477
PLAT	0.029469
FREM2	0.029420
NXNL2	0.029353
GRHL3	-0.029207
SOCS2	-0.029159
FNIP2	0.029020
TET2	0.029012
BMF	-0.028824
SMCO3	0.028805
ADAM2	-0.028793
GREB1	0.028744
ONECUT2	0.028733
ENDOD1	0.028647
RND3	-0.028612
FGFBP2	0.028610
LINC00886	0.028602
POC1B	0.028503
BLNK	-0.028477
BDKRB2	-0.028419
UST	0.028403
KLF4	0.028390
GCLM	0.028266
PPM1K	0.028216
ISG20	0.028205
EPB41L5	-0.028175
PODXL	0.028150
C12orf60	0.027936
LRIG1	0.027830
TMEM2	0.027691
NOC3L	0.027629
MXI1	0.027561
MAT1A	0.027445
SALL4	-0.027410
TBCCD1	0.027408
AIM1	-0.027406
NPY5R	0.027342
FAM46C	0.027246
SLC24A3	0.027189
ELF1	0.027170
GLUL	0.027114
SEMA3C	0.027067
IL17RB	0.027047
THBS1	0.027045
GAB2	0.026768
TMTC2	-0.026690
FAM107B	-0.026685
KIAA0895	0.026658
PRSS23	0.026652
CCND1	0.026651
KCNJ3	-0.026626
LINC01468	0.026597
FAM83A	-0.026564
NBPF4	0.026563
RASL11B	-0.026528
ID1	0.026477
PRRT2	-0.026439
PSD3	-0.026422
ABCG1	-0.026388
SGPP1	0.026235
FAIM3	0.026152
PSTPIP2	0.025998
FAM63A	0.025969
RNF43	-0.025936
RERG	0.025933
MANEA	0.025930
IER5L	0.025880
N4BP3	-0.025851
BMPER	0.025846
USP31	0.025838
SMOX	0.025810
FAM83B	-0.025803
C5AR2	0.025759
ST3GAL1	-0.025744
CYP4F11	0.025680
CPOX	0.025645
MXD1	0.025609
LRRFIP2	0.025586
FZD7	0.025219
SLC7A5	0.025181
EFNA1	-0.025177
TIAM1	0.025140
LRIG3	-0.025130
ELF5	-0.025108
MYC	0.025102
MCEE	0.024971
TMPRSS3	0.024891
AMD1	0.024794
OPN3	0.024731
NAB2	0.024691
UGT2B15	0.024517
SMIM5	-0.024147
ZSWIM6	0.024049
OLFM1	0.023987
SLX4IP	0.023968
BRIP1	0.023944
EGLN3	-0.023837
TUFT1	-0.023773
LONRF1	0.023750
DDHD1	0.023654
KIF21A	0.023639
LOC400768	0.023622
SLC37A3	0.023545
TST	0.023543
SNX24	0.023542
MTERF3	0.023535
LINC01213	0.023530
SLC19A2	0.023477
PPP1R3D	0.023470
NXN	-0.023452
LINC00936	-0.023434
DFNB31	0.023430
TRANK1	0.023285
LINC00494	-0.023150
LOC93622	0.023125
DYNLT3	0.023106
OAS1	-0.023096
PKP2	-0.023091
PRSS8	-0.023078
NCEH1	-0.023073
PARP9	-0.023059
NKAIN1	0.023033
TENM4	0.023016
S1PR3	-0.022957
ASPM	0.022850
GALNT6	-0.022746
RHOU	0.022725
KIAA0226L	0.022690
KLHL13	-0.022626
SGPP2	-0.022600
JAG2	-0.022560
MLPH	0.022446
DDX10	0.022440
FUT8-AS1	-0.022388
MAP4K3	0.022382
CERK	-0.022352
UHRF2	0.022273
LIMA1	-0.022272
IL24	0.022232
DBN1	-0.022205
CORO2A	-0.022116
LAD1	-0.022115
CHST8	0.022076
C8orf88	0.022028
LINC01016	0.022021
UGDH	0.022012
TANK	0.021965
COL21A1	0.021929
RAB17	0.021917
ZNF260	0.021901
DNAJB14	0.021895
UAP1L1	-0.021892
CDH26	0.021865
NINL	0.021856
UGCG	0.021855
RND1	-0.021852
THSD4	0.021823
MAML3	0.021822
GRAMD1C	0.021755
DUSP6	0.021753
DDX5	-0.021720
SDK2	0.021705
KIF16B	0.021686
NEAT1	-0.021652
MED13L	0.021616
VEZF1	0.021573
SOX9	-0.021572
RNF208	-0.021488
TSPYL5	0.021483
NBEA	-0.021371
FPGT	0.021354
SFXN1	-0.021353
PISD	0.021338
PGBD5	0.021336
SFR1	0.021285
SNAPC1	0.021273
KDM7A	0.021228
HTR1E	0.021164
SLC12A2	-0.021105
NCKAP5	0.021101
TLR5	0.021098
ARL13B	0.021074
SLC47A1	0.021023
IGFBP3	-0.021004
REL	-0.021003
STK17A	0.020991
PTAR1	0.020963
SPATA2L	0.020945
NAV2	0.020936
ARHGDIA	-0.020932
C8orf4	-0.020928
C8G	-0.020899
NOTCH3	-0.020897
DSCAM	0.020896
RARA	0.020836
TFPI	-0.020795
CPEB4	-0.020781
CLMN	-0.020756
CYP24A1	0.020727
TAF13	0.020696
PPAP2C	-0.020687
SEPP1	0.020685
FAM60A	0.020684
RASD1	-0.020684
TMEM120B	0.020635
SLC4A7	0.020608
TRMT1L	0.020603
CAP2	0.020600
RIPK4	-0.020577
ARL4A	-0.020570
FANCL	0.020552
HILPDA	-0.020536
KLC2	-0.020532
NBPF1	0.020522
FGF13	-0.020519
GRB7	-0.020504
PPL	-0.020489
PEX11A	0.020421
FAM105A	-0.020416
CENPB	-0.020406
ZNF750	-0.020400
BCL2L11	0.020376
BCAS3	-0.020357
TMEM243	0.020348
SLITRK4	0.020293
TMEM45A	-0.020270
TRERF1	-0.020242
SLC35E2B	0.020235
WIPF1	0.020195
ZBTB41	0.020150
RAB3D	-0.020140
TMEM194A	0.020124
RCL1	0.020110
B3GALNT1	0.020107
ALYREF	-0.020097
CAMK2N1	-0.020082
PARD6B	0.020075
HIF1A	0.020074
PLEC	-0.020045
FLVCR1	0.019970
C4orf19	0.019954
LMTK3	-0.019917
FAM198B	0.019912
AMMECR1	0.019904
ANP32A	-0.019890
DSN1	0.019888
VASP	-0.019874
TNS3	-0.019854
GLA	0.019842
MANEAL	0.019827
GADD45B	0.019810
TMEM150C	-0.019796
PPIF	0.019742
SGOL2	0.019720
ZFYVE21	0.019636
BMP4	-0.019626
UBE2T	0.019597
UBE4B	0.019595
ACSL3	-0.019586
LRRC57	0.019574
ELF3	-0.019560
C15orf59	0.019533
COL12A1	0.019513
DNAJC12	0.019501
SIDT2	0.019493
SOX3	0.019464
BMP7	-0.019453
TUBBP5	0.019440
CIPC	0.019439
GUSBP3	-0.019437
CA12	0.019397
WDR75	0.019351
ASB9	-0.019293
CCR1	-0.019284
ARF6	0.019267
DBNDD1	-0.019253
SLC25A36	0.019211
KMO	-0.019187
ANKRD36B	0.019184
RB1CC1	0.019180
SPOCD1	0.019173
JADE2	0.019151
FKBP5	0.019150
CYP1B1	-0.019148
PXN	-0.019148
HS3ST3B1	0.019109
PUS1	0.019095
TMEM170B	0.019084
NBPF11	0.019036
KRT15	0.019001
MYO16	0.019001
ATP13A3	0.018982
PIGA	-0.018973
SNAP25	-0.018932
CEBPG	0.018928
MBD4	0.018870
WDR12	0.018869
SCUBE2	0.018850
HCK	0.018825
CADM1	0.018797
GNAI2	-0.018774
SEMA3F	-0.018741
VPS37A	0.018727
MGAT2	0.018720
EDEM3	0.018698
SYTL4	0.018671
HMCN1	-0.018666
RHOD	0.018647
LOC100128416	-0.018614
MBOAT1	0.018614
PHF13	0.018585
PLEKHG1	0.018581
RPS6KA5	-0.018569
CALHM2	0.018552
BOLA1	0.018551
CISH	0.018538
MYOF	0.018510
EPHA4	-0.018417
ASNSD1	0.018404
KCTD6	0.018354
SAMD9	0.018333
CSGALNACT2	0.018329
THOC5	0.018321
ADCY9	0.018286
CLASP2	0.018281
CLIP4	-0.018268
LOC728730	0.018260
GLTP	-0.018242
PSPH	-0.018228
BANP	0.018219
RAMP3	0.018191
KIAA1522	-0.018191
CEP135	0.018189
KIAA0907	0.018156
SLC9A3R1	0.018144
MDM1	0.018131
TOP2A	0.018130
CGN	-0.018097
RRS1	0.018088
ARHGEF26	0.018087
NUDCD1	0.018085
C16orf45	0.018068
RAB11FIP1	0.018065
UGT2B17	0.018051
STEAP3	-0.018046
WISP2	0.018043
PANK1	0.018031
FLJ22184	-0.018026
CBFA2T3	0.017984
SCG5	-0.017983
ZBTB11	0.017965
KLF5	-0.017931
ENO2	-0.017917
KCNN4	-0.017909
TP53INP2	-0.017904
G2E3	0.017888
NCAPG	0.017876