!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	4-Hydroxynonenal
!smiles	CCCCCC(C=CC=O)O
!pubchem_cid	5283344
!cell_type	RKO colorectal carcinoma cell line (6 Hours after exposure to 20uM)
!organism	human
!end_metadata
HMOX1	0.499974
SFN	0.134609
GCLM	0.115153
TXNRD1	0.107764
DDX21	-0.096513
SLC7A11	0.092440
FTH1P5	0.086285
CTGF	0.082964
RRM2	-0.078785
ABHD3	0.078533
PRDX1	0.073986
C2CD2	-0.072991
HSPA4L	0.070178
BAG3	0.069520
TUBB4B	-0.068085
HSPB1	0.066172
NQO1	0.064527
SRXN1	0.063968
MRPL18	0.063427
MRPL33	0.062363
COX6C	0.061356
SRSF2	-0.060417
HSPE1	0.059835
MAT2A	-0.059561
TUBB	-0.058120
RPL9	0.057508
TALDO1	0.056749
MIF	0.055494
CCT3	0.055413
TUBB3	-0.055296
UAP1	-0.054672
HSP90AA1	0.053570
RPL27	0.052523
KPNA2	-0.052213
ANLN	0.051842
MICB	0.051218
RPL7A	0.050856
SHFM1	0.050026
G0S2	-0.049694
SFTA1P	0.049241
KLF10	-0.049017
SLC16A14	0.048819
NEDD8	0.048745
RRS1	-0.048244
CTSL	0.047649
SNRPF	0.047189
CHCHD2	0.046878
WBP5	0.046663
ATP5B	0.046410
PRDX6	0.046325
HMGB2	0.045717
MAP2K3	-0.045337
AHSA1	0.044765
SUGT1	0.044400
NEAT1	0.043850
LMNB1	-0.043737
RPS14P3	0.043634
IER2	0.042915
UBE2S	-0.042624
PITPNB	-0.042618
DKC1	-0.042557
BRIP1	0.042508
RPL41	0.042487
TMBIM6	0.042186
SSR3	-0.041905
MMADHC	0.041632
RPS29	0.041513
RPL19	0.041497
ADM	0.041121
OAZ1	0.040499
ANXA2P2	0.040422
NABP1	0.040106
DUSP5	-0.039870
PPIF	-0.039870
ABL1	-0.039334
ARPC5L	-0.038847
ZFAND2A	0.038567
SLC25A32	-0.038260
MT1G	-0.038217
GABARAPL2	0.037933
SET	-0.037878
BCL2A1	-0.037823
EIF4A3	-0.037526
RPL12	0.037354
RPL32	0.037281
UPP1	-0.036728
NDUFA1	0.036675
RPS21	0.036505
MALAT1	0.036496
TRIM28	-0.036494
HERPUD1	0.036438
EMC2	0.036426
SDCBP	0.036281
RARS	-0.035835
UHRF1	-0.035649
TRMT112	0.035644
ANP32B	-0.035213
RRP1B	-0.034843
ATP6V1C1	0.034642
CRYZ	0.034517
RPL36A	0.034378
TMSB10	0.034274
ST13	0.034257
ODC1	-0.034203
COX1	0.034140
ETF1	-0.034138
RPL24	0.034025
CCDC86	-0.033290
NOC3L	-0.033228
SELT	-0.033143
CYR61	0.033118
ARRDC3	0.033037
RPS7	0.032903
SMIM15	-0.032879
FTL	0.032845
NOP10	0.032704
PPME1	0.032698
SRSF6	-0.032694
ACTB	0.032603
AP1S1	-0.032502
REXO4	-0.032342
SLC38A2	0.032321
SELK	0.032216
MT1X	-0.032141
FTH1	0.032081
SLC35F2	-0.031867
SRP14	0.031727
IFI16	0.031495
SH2B3	-0.031479
PTDSS1	-0.031414
ATF4	0.031172
UFD1L	0.031146
IER3	-0.031101
SPHK1	-0.031089
SOD1	0.031071
SNRPD2	0.031020
SNHG1	-0.030912
CALD1	0.030908
MOAP1	0.030814
LCP1	0.030740
RPS2	0.030729
UQCRH	0.030687
EPHA2	-0.030297
XPO1	0.030252
HMGN2	0.030198
MRPL36	-0.030141
LASP1	0.030090
CIRH1A	-0.030064
RPS9	0.030062
PUF60	-0.030012
CACYBP	0.029795
RPL3	0.029631
TMEM258	0.029595
KIF5B	-0.029505
S100A16	-0.029274
FAM96A	0.029153
RPL39	-0.029044
MT1F	-0.029021
RPL28	0.028990
HMGA1	-0.028955
FABP5	-0.028939
UBA52	0.028928
UBB	0.028927
BST2	0.028816
SNX3	0.028802
RPS25	0.028666
RPL31	0.028653
STIP1	0.028545
GLA	0.028520
SLIRP	0.028462
UBC	0.028444
ATP5A1	0.028437
SERINC1	0.028340
GRPEL1	-0.028106
PHB2	0.028072
MAP1LC3B	0.028005
CTPS1	-0.027920
RPL14	0.027863
HSP90AB1	0.027843
PLAUR	-0.027839
VDAC3	0.027675
CKS2	0.027590
DNAJA1	0.027407
UBE2M	-0.027399
CLDN12	0.027399
GSR	0.027262
RPL29	0.027256
RPIA	-0.027136
TMEM165	0.027119
MAT2B	0.027087
MYL12A	0.027023
CHMP5	0.027015
RPL35	0.026985
WBP2	0.026806
MRPS2	-0.026777
SLC3A2	0.026762
FBXO30	0.026705
ACVR1	0.026655
HSD17B7	0.026653
PUS7	-0.026646
CLCN3	0.026639
RSL24D1	0.026605
FAM217B	0.026585
NACAP1	0.026573
PSMD2	0.026568
EIF6	-0.026562
PSAP	0.026558
EIF3A	-0.026550
RPL13A	0.026515
DAD1	0.026503
GADD45A	-0.026456
FEZ2	0.026372
NDFIP1	0.026323
TRIM16	0.026305
GTPBP4	-0.026140
CCNB1	-0.026083
NIP7	-0.026023
STARD3NL	0.025952
LYAR	-0.025890
ATP5J	0.025860
HNRNPAB	-0.025780
FAU	0.025729
CETN3	0.025721
NOP58	-0.025621
DNAJB4	0.025605
ALDH2	0.025588
KPNB1	-0.025565
GPX8	0.025512
HNRNPA0	-0.025482
RPS5	0.025444
GEMIN5	-0.025437
TOP1	-0.025372
HIF1A	-0.025268
LPCAT1	-0.025234
HSPA8	0.025156
RPS19	0.025142
UQCRB	0.025055
NPC2	0.025032
CHMP2B	0.024981
HMGN4	0.024955
SNHG17	-0.024941
GAPDH	0.024907
PSMB3	0.024894
MGST1	0.024860
SARAF	0.024858
RPS18	0.024797
ANKMY2	0.024770
LINC00657	0.024765
MYL6	0.024462
TFRC	0.024458
NQO2	0.024386
PHYH	0.024372
MIR22HG	0.024348
IFNGR2	-0.024290
CISD1	0.024259
COX7A2	0.024137
HSPA5	0.024100
NIFK	-0.024038
CWC15	0.024018
IPO7	-0.023986
CAP1	0.023705
TATDN1	0.023665
COX7C	0.023563
RPL26	0.023411
BAZ1A	-0.023388
TRA2B	-0.023295
NDUFA4	0.023263
PTMA	0.023235
ENC1	-0.023141
FAM136A	-0.023068
RPS13	0.023046
TMEM126A	0.023030
UBE2Q2	-0.023025
VKORC1	0.022987
HSPA4	0.022980
YBX1	0.022960
POLE3	-0.022957
RPL6	0.022796
DHX33	-0.022727
NFKB1	-0.022633
YWHAZ	0.022599
HSP90B1	0.022583
NOL11	-0.022554
RPS16	0.022547
CSK	-0.022491
DCXR	0.022481
TNFRSF12A	-0.022459
PREPL	0.022450
AXL	-0.022447
SLC7A5	-0.022363
ATP5J2	0.022283
EEF2	0.022276
CDK17	-0.022235
UQCR10	0.022228
CCNA2	-0.022200
FAM60A	-0.022172
RB1CC1	0.022154
NOLC1	-0.022078
TMEM158	-0.021995
LAP3	0.021980
VPS28	0.021944
NETO2	-0.021893
MT1M	-0.021877
GTF2B	0.021853
PRKRIR	-0.021837
PNP	-0.021723
RNASEK	0.021716
GGH	0.021710
CCNG2	0.021602
SERBP1	-0.021596
ACSL3	0.021569
GAR1	-0.021534
PSME2	0.021533
RPL23A	0.021483
HYOU1	0.021477
EIF4H	-0.021442
RNPS1	-0.021416
C5orf34	0.021398
RPS3	0.021396
PNPT1	-0.021353
GSTO1	0.021344
EIF1B	0.021248
MRPS24	0.021180
PARP4	0.021174
LGALS1	0.021172
DNTTIP2	-0.021149
BLOC1S2	0.021128
POMP	0.021119
MGEA5	0.021022
RPF2	-0.021002
BANF1	0.020979
CCDC84	0.020884
PPP1CA	0.020865
DANCR	0.020848
ANXA1	0.020758
GABPB1	0.020731
C12orf57	0.020697
TMEM14A	0.020673
ST6GALNAC4	-0.020601
GTF3C6	-0.020556
EAPP	0.020542
RPS17	0.020520
SEC11A	0.020515
PTPRO	-0.020498
ADSL	-0.020468
CTNNAL1	-0.020438
RAN	-0.020405
JAG2	-0.020339
TIMMDC1	0.020330
MRPL3	-0.020292
STARD7	-0.020219
TRMT6	-0.020208
NOM1	-0.020187
RPS20	0.020158
ANKRD27	-0.020147
SMURF2	-0.020094
POLR2H	0.020070
GOLPH3	-0.020012
SNHG15	-0.020011
PHLDA2	-0.020001
TMA7	-0.019992
PPP2CB	0.019978
CPOX	0.019972
TMEM181	-0.019953
C14orf2	0.019942
URM1	0.019878
ACTR3	0.019837
NDUFB9	0.019768
PIGP	0.019661
HAUS1	0.019660
RPL8	0.019655
PPID	0.019616
PNPLA8	0.019559
PSMA7	0.019545
PSMA6	0.019514
TSC1	0.019513
NAF1	-0.019509
CCT2	-0.019480
FUCA2	0.019476
NSA2	0.019458
DDX47	-0.019454
P4HA2	0.019441
RPL11	0.019425
NUDT19	-0.019344
TMEM138	-0.019336
GNB2L1	0.019290
RBM28	-0.019290
HSD17B11	0.019286
CLN5	0.019263
PILRB	0.019142
MYD88	-0.019121
YWHAQ	0.019082
BCAP31	0.019068
SERPINE1	0.019053
ABCE1	-0.019001
DNMT1	-0.018994
MRPL13	0.018964
ISOC1	-0.018959
PRRG4	0.018936
TPT1	0.018932
FXYD5	-0.018932
PSMC6	0.018910
PFKM	0.018907
RHOF	-0.018897
ZNF593	-0.018875
FJX1	-0.018872
PSMD4	0.018819
ZMYND19	-0.018816
MSMO1	0.018800
ADORA2B	-0.018763
LAPTM4A	0.018729
POLR2G	0.018704
PSMB1	0.018684
MTMR4	0.018665
PLAU	-0.018663
RPLP0	0.018657
ARF4	0.018654
DDOST	0.018627
GSKIP	0.018598
TYW3	0.018562
GNPNAT1	-0.018546
C1QBP	0.018515
MAP2K1	-0.018463
RPS12	0.018338
EIF3J	-0.018313
UBE2N	-0.018313
EPS8	0.018299
SUMO1	0.018289
PRPF4	-0.018287
ATP6V0E1	0.018253
SEH1L	-0.018216
GRB2	-0.018211
POP7	-0.018208
MTHFD1	-0.018196
CTR9	0.018179
CANX	0.018136
BIRC2	-0.018111
LAMTOR4	0.018049
SEC61G	0.018047
ITM2B	0.018037
PSMC5	0.018015
COX2	0.017989
ABI1	0.017984
ETS1	-0.017983
SNHG16	-0.017964
CCND1	-0.017947
SUMO2	0.017920
SRM	-0.017901
EEF1A1	0.017855
XPC	0.017847
KRT18	-0.017823
BUB1B	0.017806
SKP1	0.017802
ZC3H15	-0.017794
TPX2	-0.017778
RRAGC	0.017754
RUSC2	0.017712
TDP2	0.017711
NOB1	-0.017678
RPSA	0.017676
VAMP7	0.017671
RBM23	0.017667
GHITM	0.017660
GOT2	-0.017602
GORASP2	-0.017582
RFC4	0.017559
CALR	0.017545
SSB	0.017541
TPM1	0.017526
RAD23B	-0.017510
USMG5	0.017503
GABARAP	0.017481
BET1	0.017409
DSTN	0.017395
GLIPR1	0.017380
STAU1	-0.017353
FRMD6	0.017343
AFG3L2	-0.017342
CCND2	-0.017337
DUSP7	-0.017275
TP53I3	0.017222
MFAP1	0.017221
TSPO	0.017199
PEX5	-0.017193
ASAP1	-0.017192
NDRG1	0.017136
LAMB3	-0.017133
MT1H	-0.017131
SMTN	-0.017131
PKM	0.017098
UCK2	-0.017075
ATP6V1A	0.017067
S100A2	-0.017067
RPS27L	0.017018
CDC123	-0.017003
CDCA7	-0.016987
SRP9	0.016928
UNC50	0.016923
FAM171A1	-0.016914
NCAPD3	-0.016886