!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Pioglitazone
!smiles	CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
!drugbank_id	DB01132
!pubchem_cid	4829
!cell_type	NA
!organism	mouse
!end_metadata
S100A8	0.116349
CNTN3	0.100764
TRH	0.092929
NMBR	0.080947
CST7	-0.077285
S100A9	0.073088
CARTPT	0.073058
KCNQ5	-0.068848
IGJ	0.068066
CHL1	0.066969
RSPO1	-0.066467
CNTN6	0.066437
KRT18	0.066210
APAF1	0.065646
OTX2	0.059638
TEK	-0.059374
GPR101	0.059102
DRAM1	0.055212
LCN2	0.054534
GPR6	0.053783
CALML4	0.053222
OCA2	0.052688
QRFPR	0.051956
BAIAP3	0.051790
CXCL13	-0.051650
KLK6	-0.050714
ADAT2	0.050452
GLRA2	0.049550
COL6A3	-0.049367
CBLN4	0.048963
HLA-E	-0.048780
POMC	-0.048522
ECEL1	0.048077
VWA3B	-0.047804
TSHZ2	-0.047071
MYH7B	-0.046738
DLK1	0.046452
CORO6	-0.046275
MYL1	-0.046220
FIGN	0.045400
SAMD12	-0.045369
IFIT1B	-0.045036
LGALS3	0.044995
GALC	0.044984
PGAP1	0.044947
SYCP3	-0.044844
EFHC1	-0.044745
SLC40A1	-0.044453
TRHR	0.044309
PKIB	0.043711
PTGER3	0.043019
PGAM2	-0.042590
INMT	-0.042463
CTGF	0.041997
LRRN4	0.041965
SCN4B	-0.041748
DNAJB14	-0.041550
RBP1	0.041463
DZIP1	-0.041221
CCNB1IP1	-0.040516
KCNE2	0.040433
ARHGAP6	0.040209
DSC3	0.040206
HIST1H4I	-0.039997
TMEM231	0.039897
RSPH4A	0.039788
DNAH7	0.039691
PRKG2	0.039595
SERPING1	-0.039568
CCDC153	0.039465
VGLL3	0.039352
CXCL6	-0.039244
MYH7	0.039198
KLF2	-0.038630
ESR1	0.038560
SHOX2	0.038481
MCU	0.038405
CD68	-0.038279
PNMA1	0.038240
APOD	-0.037674
SSTR1	0.037193
NXPH2	0.037101
RXRG	0.037065
COL5A2	-0.037017
ACE	0.036645
EFHD2	0.036614
TIMMDC1	0.036450
TMPRSS11A	0.036291
CD44	0.036203
ZER1	-0.036147
ABCB1	-0.036140
AGO2	-0.036001
FHAD1	0.035928
SLC26A8	-0.035738
ANGPT1	0.035631
SLC25A45	-0.035464
TAC3	0.035406
ARSJ	0.035385
PQLC3	0.035250
DDIT4L	-0.034910
EPB41L4A	0.034801
PLIN4	0.034627
LUM	-0.034587
CD34	-0.034298
GPX3	0.034187
MIA	0.034036
ECHDC3	-0.033978
CX3CR1	-0.033738
ZBTB12	-0.033644
MEST	0.033628
LRG1	0.033601
CTHRC1	-0.033494
ITIH5	-0.033281
TFG	-0.033205
DNAJC28	0.033193
NINJ2	-0.033094
NR4A1	-0.032749
HEG1	-0.032737
RGS16	0.032699
YIPF4	-0.032519
FBXO46	0.032466
NGB	0.032416
ITM2A	-0.032402
C2orf40	0.032378
ITGB2	-0.032304
ARHGAP26	0.032243
ATP13A5	-0.032148
ZFHX2	0.032128
AOX1	-0.032037
ATP2B4	0.031909
C2CD4C	0.031785
ARC	-0.031775
SULF1	0.031585
EXPH5	-0.031550
KRT8	0.031522
AVP	0.031514
FAM60A	-0.031477
CSRP2	0.031425
BTG2	-0.031336
ICAM2	-0.031275
RAPH1	-0.031039
THBS4	-0.030949
TMEM91	0.030900
CPLX3	0.030697
ITGAM	0.030565
EMR1	-0.030548
SOX11	0.030541
SOSTDC1	0.030414
FOXC1	-0.030337
CHRNA5	0.030295
SYT9	0.030251
PRDM5	-0.030099
FAM205A	0.029955
HILPDA	0.029901
FPR2	-0.029886
MPEG1	-0.029789
CXorf64	0.029698
PLCD3	-0.029389
RORB	-0.029384
TMEM212	0.029338
NOG	0.029279
MLF1	0.029181
KCNAB3	-0.029096
CD74	-0.028876
MAL2	-0.028742
SNAPC4	-0.028665
ALDOB	-0.028594
CCDC51	0.028575
HES1	0.028447
HSD11B1	-0.028417
ADRA2A	0.028365
KCNF1	0.028271
CXCL10	-0.028103
COL5A1	-0.027894
TNNT1	0.027764
NREP	-0.027715
LAMA2	-0.027686
FAM196B	0.027622
BTG1	-0.027619
HTR1A	0.027454
GLIS3	-0.027416
IFIT3	-0.027409
PTTG1	-0.027383
DZIP1L	-0.027291
PDDC1	0.027290
NGF	0.027281
ZNF354B	0.027250
P4HA2	0.027247
SCNN1A	-0.027140
TRPC3	-0.027110
IGFBP6	-0.027053
LZTFL1	0.027023
NUF2	-0.027015
BMP2	0.026943
HPCAL1	0.026895
BMP4	-0.026746
VTN	-0.026631
KPNA4	0.026519
PLXNC1	0.026500
MCM8	-0.026457
NKX6-2	0.026457
ACVR1C	-0.026449
VWA5B2	-0.026441
CHI3L1	-0.026419
SRSF2	0.026396
TRIOBP	0.026376
SHROOM4	-0.026214
MRAP2	0.026156
SLC18A2	0.026153
OVGP1	-0.026122
WNT10A	-0.026038
CXCR4	0.025989
PGLYRP1	-0.025966
VWF	-0.025920
ATP6V1H	-0.025900
SSTR2	0.025880
ZMYM1	0.025846
CTSH	-0.025831
SYT4	-0.025813
KIAA1715	0.025742
TENC1	-0.025713
FAM149A	0.025626
NPAS4	-0.025623
CCNE2	0.025608
GNB4	0.025401
SPP1	0.025323
NECAB1	0.025302
TUFT1	0.025287
TRPC5	-0.025285
HES5	0.025285
RBM11	0.025274
DYNLRB2	0.025267
KLF10	0.025198
DLEU7	0.025131
FN1	-0.025095
ASPA	-0.025048
IFT20	-0.024959
PTPRO	0.024940
SYT10	0.024915
MFSD9	0.024891
SAMD5	-0.024825
CLEC7A	-0.024806
WDR25	0.024783
RHPN2	0.024782
EFEMP1	-0.024759
ARHGEF4	-0.024665
C16orf87	0.024651
FST	0.024627
EFNB2	0.024568
TMEM255A	0.024558
GPR133	-0.024502
RYR3	-0.024428
UGGT2	0.024423
IFITM3	-0.024374
JAG1	-0.024315
PENK	0.024289
SYTL2	-0.024286
AGT	0.024271
A2M	0.024257
CCR6	-0.024255
LDOC1	-0.024188
SHB	0.024121
HHATL	-0.024091
SGPP2	-0.024059
GFOD2	0.024037
SLC8B1	-0.024012
PADI2	-0.023993
CACNA1E	0.023955
SLA	0.023932
TMEM81	-0.023918
SNAP91	-0.023915
TCFL5	0.023801
C1orf54	-0.023779
GRM3	-0.023773
ACY1	-0.023730
PLD4	-0.023700
TAF1	0.023699
F5	0.023649
SDSL	-0.023621
C15orf65	0.023593
ZBTB8B	0.023590
SYCE2	0.023586
DSTN	0.023571
EMCN	-0.023532
BGN	-0.023523
CD47	0.023516
DNAH5	0.023513
TMEM177	0.023510
KITLG	0.023438
ACVR2A	0.023406
KCNH5	-0.023332
RBM20	0.023270
BEND3	-0.023204
ARPC1B	-0.023141
C9orf69	-0.023123
EGLN3	0.023119
DAPL1	-0.023112
DUSP1	-0.023072
RAPGEF4	-0.023037
LUZP1	-0.023033
SAPCD1	-0.022976
PLLP	-0.022931
GREM2	0.022920
OMD	-0.022903
CAMK2D	0.022861
KCNJ16	0.022853
PLEKHD1	0.022843
STAC2	-0.022803
CAV1	-0.022738
OLFML1	-0.022711
PROM1	-0.022682
B3GALT6	0.022678
TOX	-0.022670
SLC29A1	0.022668
ZIC2	-0.022656
EHD4	0.022613
IGFBP3	0.022533
BEND6	0.022516
C9orf135	-0.022399
CENPJ	0.022370
CAST	-0.022360
B3GALT1	0.022333
AKR1C3	-0.022316
FZD1	0.022298
TREM2	-0.022277
VAT1L	0.022276
RAB39A	0.022263
CLIC6	0.022262
RRP8	0.022251
TIE1	-0.022198
ETAA1	0.022196
SREBF1	-0.022193
SLC27A2	0.022180
GJB1	-0.022169
KCTD14	-0.022169
ESAM	-0.022163
COPZ2	-0.022159
KCNS1	-0.022142
AK7	0.022101
EPOR	0.022066
MUM1L1	0.022032
OSBPL3	-0.021986
CD36	0.021908
SPATA7	-0.021902
RGS11	-0.021901
GBP4	-0.021900
ADCYAP1	0.021892
CCDC3	0.021891
NAALAD2	-0.021883
MKX	-0.021832
KLHL40	-0.021827
ZNF575	0.021814
SLC7A3	0.021799
GBP2	-0.021791
PRSS16	0.021775
PTPRB	-0.021682
ST6GALNAC2	-0.021638
PRDX6	-0.021611
GJB2	-0.021602
GLS2	-0.021569
ENPP1	-0.021568
CTSE	-0.021528
TMEM125	-0.021527
COL3A1	-0.021522
CPNE9	-0.021432
MID1	-0.021402
HERC2	-0.021377
GPATCH11	0.021362
MYL9	-0.021301
ABCA8	0.021231
STEAP1	0.021195
GMIP	0.021193
MECR	-0.021184
TSEN54	-0.021174
VGLL4	-0.021168
MAN2A1	-0.021155
BICC1	-0.021119
MDM1	0.021106
PTCHD4	-0.021046
PDLIM2	-0.021045
RESP18	0.021032
TOX3	0.020981
TAL1	0.020962
FAM122B	0.020952
NTNG2	-0.020940
PHKA2	-0.020930
HIST1H3G	0.020898
HIST1H3C	0.020878
MEI1	-0.020824
LYPD1	0.020813
DHRS13	0.020798
PLA2G4E	-0.020792
TNNC1	0.020772
WFIKKN2	0.020769
DEDD2	0.020736
SPTSSB	-0.020733
CNIH3	0.020679
SUSD5	0.020670
MARS2	0.020663
HRH1	0.020662
NNAT	0.020620
ABCA1	-0.020595
DAPP1	0.020561
EMB	0.020557
LIG1	-0.020539
FAM110A	0.020446
ICA1L	0.020404
RAB34	-0.020355
RPUSD4	0.020348
SAP30	0.020306
NXPE4	-0.020299
FADS6	-0.020185
MYL4	0.020182
FAM83D	0.020150
LAIR1	-0.020138
TMTC4	0.020106
CDH1	-0.020048
APLN	-0.020036
HS3ST3A1	0.020018
BMPER	-0.020014
GRIN2A	-0.019998
CNDP1	0.019981
FAM120C	0.019954
CDO1	0.019947
ZDHHC22	0.019912
KCNA3	0.019899
ESD	0.019845
EOMES	-0.019824
DCUN1D3	0.019800
DSN1	-0.019779
MAP2K6	0.019778
RSPH1	0.019750
URB1	-0.019735
RGL3	-0.019734
PIANP	0.019724
SATB2	-0.019675
COL1A2	-0.019644
ANKRD29	-0.019640
ERCC6	-0.019638
UNC5D	0.019557
FTSJ2	0.019526
CNKSR3	0.019491
NOP16	0.019472
RAB37	0.019465
ITIH2	-0.019463
C10orf10	-0.019454
NIPSNAP3A	0.019446
NDUFS1	-0.019439
PLCXD3	0.019401
C5orf28	0.019401
LGALS9B	-0.019399
CCDC117	0.019378
MMRN2	-0.019364
TGFBI	-0.019331
MALT1	-0.019299
PPP1R3B	0.019294
MIIP	0.019284
CTSZ	-0.019282
GAS2L3	0.019275
SYT2	-0.019261
METTL24	0.019258
CSF3R	-0.019251
CLDN5	-0.019248
MIS12	0.019244
WNK1	-0.019199
PDGFC	0.019187
GABRA3	0.019178
FMOD	-0.019173
ADIPOR2	0.019143
CHRNA7	0.019120
TCF7L2	0.019118
LIG4	0.019103
HIST3H2A	0.019098
SOD3	0.019090
ADSSL1	-0.019062
SAMD9L	0.019055
C6orf222	0.019022
IRF2	0.019015
MOXD1	0.019013
HAP1	0.019002
CDKN1A	0.018995
TF	-0.018976
PCDHB14	0.018973
FBXO10	0.018967
SH2B2	0.018966
ATP10B	-0.018941
PLCXD2	-0.018927
HGF	0.018925
SENP8	0.018910
ARRDC2	0.018908
RFC5	0.018893
KLHL6	-0.018873
AIM1L	-0.018853
ORC2	0.018840
CDH7	0.018838
CELSR1	-0.018832
RPS6KB2	-0.018832
GAREML	-0.018808
APOLD1	-0.018797
MME	0.018788