!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Caerulein
!smiles	CC(C(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C5CCC(=O)N5)O
!pubchem_cid	16132921
!cell_type	Pancreas (Mist1 knockouts)
!organism	mouse
!end_metadata
KRT18	0.364247
KRT8	0.358688
NUPR1	0.268033
DSTN	0.252645
CLU	0.173324
ACTG1	0.167910
ACTB	0.164203
GCLC	0.152806
EFHD2	0.148383
SPP1	0.141305
LRG1	0.118125
FDX1	0.106653
NDRG1	0.099987
ACTN1	0.089628
ACTN4	0.087706
CTSV	0.078258
RAP1GAP	-0.074523
SSFA2	-0.068518
CCKAR	-0.067981
SERPINI2	-0.066301
GLUL	-0.066079
KIAA1147	0.065277
RPL3	-0.065100
HSPB1	0.065054
CDH1	0.064025
RPLP0	-0.063876
CPB1	-0.062336
RPS2	-0.060301
HSPA8	0.059705
SEL1L	-0.059604
CPA2	-0.058902
P4HB	-0.058809
PAH	-0.057197
MCFD2	-0.055552
DMBT1	-0.055469
PNLIPRP2	-0.055150
DAP	-0.054457
SDC1	0.054050
RPS12	-0.053939
HERPUD1	-0.053401
EDEM2	-0.052399
RPS27A	-0.051159
ZG16	-0.051058
XBP1	0.050866
PPIB	-0.050457
CEL	-0.050323
RTN4	0.050265
REG3A	0.050197
RPS3	-0.049565
TFF2	-0.049532
TXNIP	-0.048582
SERINC3	-0.048195
HMGCS2	-0.047755
GGH	-0.047746
RPL7A	-0.047521
TAGLN2	0.047051
CEACAM1	0.046869
KIF21A	-0.045963
RNASE4	-0.045906
EPCAM	0.045574
ARPC2	0.045463
RPS14	-0.045358
SLC41A1	0.044615
REG3G	0.044441
REG1A	-0.043666
GJB2	0.042117
IGJ	0.041943
SOCS3	0.041919
FGL2	0.041059
AHCY	-0.040521
FAM134B	-0.040518
SESN1	-0.040422
SEPP1	-0.040139
GORASP2	-0.039735
RPL28	-0.039649
CLDN7	0.039588
CUZD1	-0.039328
IFRD1	-0.038962
HSP90AA1	0.038944
EIF4A2	-0.038853
YWHAH	0.038843
RPLP2	-0.038729
TUBA1B	0.038696
RPL38	-0.038507
FKBP5	-0.038464
CLDN10	-0.037022
RPL11	-0.036912
DSP	0.036200
ITGA6	0.035491
PFN1	0.035404
CHCHD2	-0.035187
GIF	-0.035148
RPL23	-0.035136
LDHA	0.034871
CLIC1	0.034447
PNLIP	-0.034371
EDEM1	-0.034348
ATP1B3	0.034272
GSTM1	-0.034242
PSMD8	0.033933
PPIA	0.033582
ARHGDIA	0.033430
TMEM131	-0.033412
APPL2	-0.033203
SERPINB1	0.033036
HSPA5	0.032787
PCBP1	0.032681
TUBB	0.032546
ANXA2	0.032157
RPL27A	-0.031819
ALDH1A1	-0.031772
RNASE1	-0.031336
ATF5	0.031252
TPT1	-0.030878
TNFRSF12A	0.030797
HMGCS1	0.030785
SPINK1	0.030392
GADD45B	0.030347
GNMT	-0.030211
JAK2	0.030075
NFATC1	0.030062
FAM129A	0.030034
PABPC4	-0.030013
HSP90B1	-0.029491
RELA	0.029374
PHF10	0.029078
RBBP7	0.029060
SPINT1	0.028804
YWHAG	0.028749
FBXW11	0.028681
SRSF6	-0.028424
LCN2	0.028414
SERPINB6	0.028371
SLC7A8	-0.028295
NARS	0.027873
HPGD	-0.027757
ADCK4	0.027589
GUCD1	-0.027347
SMARCA1	-0.027137
FAM46C	-0.027059
TUBA4A	0.026744
NAT8	-0.026555
RPL13A	-0.026486
RNH1	0.026409
SQSTM1	0.026332
COX6A1	-0.026279
RAC1	0.025930
GATM	-0.025911
CFL1	0.025785
CELA2A	-0.025777
HADH	-0.025698
SAT1	0.025533
MAT1A	0.025516
RPL6	-0.025455
PPAP2B	-0.025180
RPS28	-0.025127
LGALS9B	0.025044
DNAJB11	-0.025014
MAP2K3	0.025010
RPS8	-0.024948
CSRP1	0.024727
CLIC4	0.024705
SRXN1	0.024694
RPS5	-0.024607
DNAJB9	0.024532
ERO1LB	-0.024491
REG1B	-0.024391
ASNS	0.024366
SDCBP	0.024332
RCAN1	0.024086
SLC25A5	-0.024014
RPL13	-0.023825
PDCD4	-0.023767
GARS	0.023297
PRPSAP1	0.023262
TOB1	-0.023203
PGK1	0.023167
TMEM30B	-0.023158
PRSS2	-0.023065
LAMP1	-0.023006
UBC	0.022964
EZR	0.022795
PCBD1	-0.022775
CTRB2	-0.022645
RPL9	-0.022386
RNF11	0.022280
ASB11	-0.022258
LAPTM4A	-0.022154
CDC42EP5	0.022118
SEC62	-0.022012
CPA1	-0.022002
ST14	0.021947
NBR1	-0.021939
SPTSSA	-0.021824
CEP85	0.021819
RPL21	-0.021757
MSRB1	-0.021709
RPL5	-0.021513
PDIA3	-0.021499
CEBPA	0.021413
IAPP	-0.021300
CTRC	-0.021179
CTRL	0.021176
TIMP1	0.020996
TMBIM6	-0.020963
PLIN4	-0.020896
S100A16	0.020888
CTSB	0.020832
IVNS1ABP	-0.020766
RPS9	-0.020756
FURIN	0.020693
RAN	0.020494
RPS7	-0.020488
NR0B2	0.020483
PLIN2	0.020379
GAPDH	0.020339
SH3BGRL3	0.020191
MDH1	-0.020068
TOP1	0.020064
ETFB	-0.020011
M6PR	0.020001
PTPLA	0.019963
GGT1	-0.019945
WARS	-0.019916
ANKRD10	0.019661
PIM3	-0.019638
PTF1A	-0.019555
CSTB	0.019516
MAP1LC3B	-0.019421
TMED2	-0.019331
LITAF	0.019285
FLNA	0.019239
INS	-0.019141
RAD23B	0.019140
EEF1B2	-0.019138
HIST1H1C	-0.019128
QDPR	-0.019005
RPS24	-0.018967
ETFA	-0.018877
GPAM	-0.018867
AAMP	-0.018814
GSTM5	-0.018737
FABP5	0.018689
ECI2	-0.018684
TNFAIP8	0.018586
CLPS	-0.018585
TMEM230	-0.018551
NDUFV3	-0.018550
BNIP3	-0.018545
SARAF	-0.018416
ZYX	0.018353
HP1BP3	-0.018341
SLC25A3	0.018296
HIBADH	-0.018271
CEBPD	0.018257
PLEC	0.018194
EEF1G	-0.018190
WSB2	0.018185
VKORC1	-0.018154
RPL10	-0.018062
SLC6A9	-0.018010
CPT1A	-0.017958
MYL12B	0.017896
SDS	-0.017867
LGALS1	0.017866
FLOT2	0.017803
PNLIPRP1	-0.017694
MANF	-0.017677
PPP2CA	0.017595
SLC39A14	0.017586
RPS15	-0.017557
RGS11	-0.017446
KIAA1522	0.017386
TNFRSF1A	0.017174
GAL	0.017130
AP3S1	-0.017122
IQGAP1	0.017064
EIF4EBP1	0.017031
WBP5	-0.017016
CHMP4B	0.016888
HADHB	-0.016883
RBMS1	0.016859
SYT12	0.016810
VMP1	0.016795
CA9	0.016769
AKIRIN1	0.016743
RELL1	0.016710
ADK	-0.016387
PICALM	0.016373
HID1	0.016351
MORF4L2	0.016206
YARS	0.016202
BCL3	0.016001
RPS13	0.015958
EI24	-0.015952
CA3	-0.015911
HSPD1	-0.015860
LARP1	-0.015817
CYP39A1	-0.015793
AP1AR	-0.015748
TMEM97	-0.015682
PCBP2	-0.015679
RABAC1	-0.015647
MYO18A	0.015631
YWHAZ	0.015591
EIF3F	-0.015489
MYH9	0.015461
SGK1	-0.015460
LYPLA2	0.015452
RPS29	-0.015451
CLTC	0.015434
JUP	0.015424
ELOVL1	0.015423
SDF2L1	-0.015413
REEP5	-0.015407
GNG5	0.015342
B4GALT1	0.015319
SPNS2	0.015297
VDAC2	-0.015245
MAGT1	-0.015242
ARMCX2	0.015214
VCL	0.015122
IDH1	0.015097
RPL8	-0.015069
UBR5	0.014997
IVD	-0.014916
RHEB	0.014911
KRT19	0.014911
UAP1L1	0.014910
RPL35	-0.014892
TRAPPC10	-0.014848
CTNNA1	0.014842
DBI	0.014842
UBE2D3	0.014718
ARL3	-0.014711
POR	-0.014691
BCL2L1	0.014688
GPR108	-0.014686
PEX11A	-0.014682
HIF1A	0.014624
CFD	-0.014572
PSENEN	-0.014566
FBXO31	-0.014563
RAP1B	0.014534
FAU	-0.014485
DBT	-0.014474
RPL26	-0.014471
DERL3	-0.014380
CLDN3	0.014246
CXXC5	0.014178
RP9	-0.014164
SEL1L3	0.014103
HGFAC	-0.014091
RPS18	-0.014066
LRRC59	0.014058
FETUB	0.014016
IPPK	0.014000
RPS11	-0.013995
CRELD2	-0.013940
VIMP	-0.013875
AES	-0.013872
LNX2	0.013861
ANPEP	-0.013857
COL3A1	-0.013842
NCKAP1	0.013834
CNN3	0.013833
GNB2L1	-0.013833
YWHAE	0.013825
MID1IP1	-0.013760
UBXN6	-0.013758
HIPK2	0.013635
RPS17	-0.013627
UGDH	0.013577
SEC23B	-0.013565
SLC38A5	-0.013518
SQLE	0.013512
ST5	-0.013397
RPL4	-0.013325
PHF23	0.013297
PIGF	-0.013201
DCN	-0.013152
AGO2	0.013146
SEC31A	-0.013119
ACAT1	-0.013116
ANXA11	0.013077
TPD52	0.013058
METAP2	-0.013057
MYO1C	0.012975
STX12	0.012956
RPSA	-0.012924
TJP1	0.012912
GLUD1	-0.012847
PLP2	0.012832
OS9	-0.012745
EIF5A	0.012710
MRFAP1	-0.012640
ATF4	0.012639
SOCS2	0.012636
TMEM147	-0.012584
GSTO1	-0.012579
PNP	0.012561
MARC2	-0.012523
CYC1	-0.012482
GSTM3	-0.012465
PPP4R1	0.012394
HINT3	-0.012372
TXN	0.012327
PDCD6	0.012319
RPN2	-0.012242
UQCRB	-0.012229
SLC25A39	-0.012147
LUC7L2	-0.012107
SRM	-0.012105
OAT	-0.012077
RAP1A	0.012076
FKBP1A	0.012053
ALDH6A1	-0.012033
EIF5	0.011977
FLNB	0.011975
KLF15	-0.011924
ANO1	0.011908
ATP6V0E1	0.011908
LSR	0.011901
EXTL3	-0.011879
SRSF2	0.011873
ATXN7L3	0.011811
TUBA1A	0.011808
SYVN1	0.011730
BCKDHB	-0.011678
PPP2R1A	0.011673
GPSM1	-0.011599
ZNF503	-0.011541
MLEC	-0.011499
NDRG2	-0.011494
CLDN4	-0.011488
GCSH	-0.011463
RRAS2	0.011438
STARD7	-0.011382
CNPPD1	0.011380
SPHK1	0.011313
YPEL3	-0.011308
ACADSB	-0.011302
MRPS18B	0.011290
LPL	-0.011241
CANX	-0.011190
PSMA4	-0.011187
NEK7	0.011165
IPO7	0.011128
UPP2	-0.011066
CDC42EP1	0.011055
DYNLL2	-0.011053
OAZ1	-0.011017
URI1	-0.011008
PAICS	-0.011007
RHOG	0.010987
PTDSS1	-0.010941
CD81	-0.010909
SLC38A3	-0.010884
AKT2	0.010880
FKBP2	-0.010877
HIGD2A	-0.010820
ANXA5	0.010804
MRPS34	-0.010794
ATP6V1B2	0.010769
DAD1	-0.010752
ATP6AP2	0.010750
AMY2A	-0.010744
ETS2	0.010742
PLOD3	0.010737
ACTR3	0.010693
RMND5A	-0.010687
MBNL1	-0.010670
DNAJC3	-0.010651
ATP5J	-0.010648
THBS1	-0.010644
ARHGEF5	0.010634
AP1B1	0.010631
CYP2E1	-0.010625
RPL27	-0.010618
EIF3K	-0.010616
KDELR1	-0.010600
EIF6	0.010586
AKR1A1	-0.010521
TFG	0.010517
BZW1	0.010504
TPM3	0.010490
UBE2G1	0.010487
SLC35D1	-0.010467
SRP68	-0.010450
MVP	0.010439
CAPN2	0.010423
CCPG1	-0.010410
NDUFS2	-0.010358
ARL1	-0.010307
SPARC	-0.010294
ATP5H	-0.010287
PLK2	-0.010278
RPL15	-0.010252
CHAC2	-0.010240
LTBR	0.010236