!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Tretinoin
!smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
!drugbank_id	DB00755
!pubchem_cid	444795
!cell_type	cranial neural crest - 6 Hours
!organism	mouse
!end_metadata
HOXA5	0.203237
RPS23	0.141015
TUBB	-0.132936
HNRNPM	-0.126224
PSMA3	0.120637
EEF2	-0.119639
TUBA1C	-0.117142
UQCRQ	0.113944
SRSF11	0.108191
PKM	-0.106715
TAGLN	-0.104255
GLRX3	0.091154
TMOD3	0.091091
TUBA1B	-0.091073
ARF1	-0.088599
HSP90AB1	-0.086592
TUBA1A	-0.084760
CTGF	-0.083991
PSMA6	0.083939
TRIM28	-0.083081
KRTCAP2	0.082592
DNAJA1	0.082413
ANXA2	-0.078744
RPL28	0.078661
UQCRB	0.076711
B2M	0.076044
AAMP	-0.073879
SELT	0.072565
AKR1A1	-0.072278
CSNK1G2	-0.069526
RPS26	0.069498
PPID	0.068321
DDB1	-0.067853
RPS28	0.067741
ARPC4	-0.067571
RPS27A	0.067306
AHNAK	-0.065934
FABP5	0.063821
ARHGDIA	-0.062935
LGALS1	0.061152
PDIA4	-0.060973
CORO1C	-0.060873
DDX39B	-0.060205
RPL18	0.059806
RAB18	0.059680
RAC1	-0.059274
BASP1	-0.058544
COX6A1	0.058382
CSN3	0.058054
NCL	-0.057436
GLIPR2	-0.056801
HINT1	0.056535
COX17	0.056454
JTB	0.056416
RPS7	-0.055630
ATP5O	0.055556
HDGF	0.055547
NT5DC2	-0.055437
KRT8	-0.055345
CDC37	-0.055047
C14orf2	0.054939
RPL37A	0.054874
MRPS21	0.054709
SERPINH1	-0.053566
SLC39A7	-0.053146
ZWINT	0.053093
RPS15A	0.053079
PABPN1	-0.052474
YWHAZ	-0.052434
PTP4A1	0.052363
GNB2	-0.051958
TUBB3	-0.051945
ATP6V0B	-0.051894
LAPTM4A	0.051696
ACTB	-0.051595
CDK4	-0.051490
PRDX2	0.050338
PRRX2	-0.050184
UQCRHL	0.050124
PABPC1	-0.049282
ROMO1	0.049149
LAMP1	-0.048930
PPP2R1A	-0.048519
PTOV1	-0.047841
SRSF9	-0.047755
KCTD10	-0.047497
TPT1	0.047201
GNG10	0.046840
NDUFA5	0.046779
TMX1	0.046719
RPS10	0.046692
GAPDH	-0.046290
SSRP1	-0.046058
EIF6	-0.045934
GOLPH3	0.045823
DDAH2	-0.045664
CSRP2	-0.045146
HIF1A	0.044951
PTPN1	-0.044848
TGFB1I1	-0.044596
CFL1	-0.044302
EIF3C	-0.043984
SPNS1	-0.043951
CTSD	-0.043830
PSMB6	0.043827
RPS3	0.043667
NHP2L1	0.043331
CCT4	0.042934
FZD2	-0.042746
MFGE8	-0.042719
HNRNPD	-0.042634
TPBG	-0.042626
C20orf24	0.042367
CDC20	-0.042048
PTPRS	-0.041938
RBP1	0.041845
RPS12	0.041388
SNRPD3	0.041368
KLF6	-0.041338
CSDE1	0.041179
PLK2	-0.041140
NDUFC1	0.040850
SDHAF1	0.040823
H1F0	-0.040751
CTNNB1	-0.040592
RPLP0	0.040183
POLR2G	0.040026
SEC61A1	-0.039953
ARF5	-0.039840
CKS2	0.039799
PCBP2	-0.039596
NDUFA7	0.039429
STRAP	0.039016
SPARC	-0.038968
DYNC1H1	-0.038874
MARCKSL1	-0.038725
ATP1B3	0.038463
NDUFS2	-0.038271
MIDN	-0.037943
HOXA1	0.037778
TMED7	0.037675
RPL5	0.037668
NDUFS6	0.037573
ATF4	-0.037486
SHISA5	-0.037336
TPI1	-0.037311
ID3	-0.037262
UBL5	0.037231
CDK2AP1	-0.037139
SAFB	-0.037128
NPM3	0.036896
MAGED2	-0.036859
PLP2	-0.036857
SND1	-0.036786
CYTH2	-0.036725
SAE1	-0.036657
EGLN2	-0.036536
CSNK1E	-0.036218
FSCN1	-0.036207
VBP1	0.036152
GPC3	-0.036110
EIF4A2	0.036107
PARK7	0.036097
HSPE1	0.035930
MRFAP1	-0.035833
ANAPC2	-0.035730
RNPS1	-0.035648
GNAS	-0.035624
CHORDC1	0.035505
SAR1A	-0.035353
POLR2L	0.035264
SOX2	0.035181
UBE2L3	-0.034930
NPC2	-0.034925
BSG	-0.034846
MAGED1	-0.034788
USP1	0.034673
WBP1L	-0.034612
CETN3	0.034571
HSP90B1	-0.034562
CSRP1	-0.034401
ATP6V0C	-0.034336
PSMC6	0.034333
SRSF2	0.034171
TAGLN2	-0.034068
TNPO2	-0.034032
SPATS2	-0.034017
DCUN1D5	0.033985
TRIP6	-0.033928
SAT1	-0.033821
SFT2D1	0.033513
GDI1	-0.033385
ZFP36L1	0.033354
NHP2	0.033296
FABP7	-0.033207
MYADM	-0.033168
NDFIP1	0.033104
HIGD2A	0.033081
RPL8	-0.033073
SLC3A2	-0.033021
HOXB5	0.032720
ANAPC11	0.032710
CNBP	0.032540
VCL	-0.032490
IDH2	-0.032469
WDR1	-0.032404
MCM7	-0.032339
UHRF1	-0.032308
UBE2N	-0.032199
ITM2C	-0.032172
HARS	-0.031974
TDG	-0.031929
NDUFAB1	0.031868
VPS4A	0.031658
CTBP1	-0.031526
EIF3D	-0.031333
MAD2L1	0.031329
MYL12A	0.031307
HNRNPH1	-0.031305
THRAP3	-0.031178
TRA2B	0.031080
PSMA5	0.030853
CRABP2	0.030780
ARFGAP2	-0.030735
RNF11	0.030732
CMTM7	0.030651
GTF2I	-0.030648
OSTC	0.030564
TOMM7	0.030350
UQCRC1	-0.030282
ANAPC5	-0.030230
RPS5	0.030197
CCT5	0.030093
MYEF2	0.030053
NREP	-0.030018
CCNB1	0.030017
SOX11	-0.029966
ASNA1	-0.029877
PRDX1	0.029817
GTF2B	0.029801
COL5A2	-0.029762
PPIC	0.029678
RSL24D1	-0.029631
BIRC6	0.029604
BIN1	-0.029514
CACYBP	0.029505
EIF2S3	-0.029306
ARGLU1	-0.029295
SKAP2	0.029283
PRMT1	0.029162
PPP4C	-0.029047
CALU	-0.028982
ACLY	-0.028943
ABRACL	0.028785
SEC11A	0.028682
KIAA1191	-0.028566
RPS19	0.028526
LRRC59	-0.028521
FKBP1A	-0.028519
JUND	0.028371
ACAA2	-0.028311
POLR3K	0.028269
HSPA9	-0.028141
SEC61G	0.028117
SURF4	-0.027973
MYH9	-0.027902
YIF1A	0.027830
SLC12A2	0.027684
CNOT1	-0.027663
PCNA	0.027661
CYB5A	0.027601
SYPL1	0.027573
RAB11B	-0.027415
ATP6V1G1	0.027400
COPS8	-0.027293
ITM2B	0.027214
DAZAP2	-0.027190
LRWD1	-0.027189
SLC38A4	-0.027143
LIMA1	-0.027116
ARG1	0.027097
SKP1	0.027091
CAB39	-0.027057
MORF4L1	-0.027022
MCAM	-0.026902
SARAF	-0.026851
ABCF1	-0.026845
TP53	-0.026804
LDLR	-0.026768
TRPC4AP	-0.026697
AHCYL1	-0.026650
GNB1	-0.026512
IMMP1L	0.026512
TXNL4A	-0.026437
TIMM17A	0.026421
KLC1	-0.026399
CAPNS1	-0.026303
PPM1G	-0.026303
FLOT1	-0.026280
MBD3	-0.026244
MEST	-0.026218
EIF3B	-0.025974
GNG5	0.025844
FTH1	-0.025805
BANF1	-0.025755
UBE2G1	0.025700
PDCD5	0.025583
SERPINB6	-0.025505
NUCKS1	-0.025487
C7orf55	0.025462
MED27	0.025368
SOD1	-0.025352
PSMD14	0.025326
IER2	-0.025249
AP1S1	-0.025216
HSPA5	-0.025183
CNIH1	0.025174
TMEM165	0.025154
RPS17	0.025131
TIMP3	-0.025092
TMEM41B	0.025053
HSD17B12	0.025047
HAT1	0.024986
PRKCSH	-0.024756
CSTB	0.024726
SGTA	-0.024584
IGF2BP2	-0.024583
VASP	-0.024521
CBFB	0.024520
PRDX6	0.024501
TIMM23	0.024490
PFDN2	-0.024466
PRKAR1A	0.024435
PKP4	0.024320
LMNA	-0.024273
TNPO3	-0.024260
YBX1	-0.024240
KPNB1	-0.024187
FAM120A	0.023912
PSMD3	-0.023882
SPSB1	0.023841
NONO	-0.023841
RHOB	-0.023813
C11orf58	0.023765
EIF3G	-0.023706
DPM3	0.023589
NARS	0.023577
COL1A2	-0.023525
CKS1B	0.023421
MRPL52	0.023411
USP5	-0.023394
DNTTIP2	0.023367
RNASEK	-0.023337
HSD17B10	0.023227
CLIC4	-0.023207
HPRT1	0.023151
STMN1	-0.023119
SEPT7	-0.023105
TIMM13	0.023100
CD81	-0.023090
YWHAG	-0.023061
PSMD4	-0.023041
CADM1	-0.022959
RUVBL2	-0.022936
C19orf43	-0.022916
EEF1A1	-0.022907
COMMD3-BMI1	0.022850
ILK	-0.022749
ADH5	0.022680
CNN2	-0.022636
GNAI3	-0.022530
HDAC5	-0.022454
STUB1	-0.022423
SNX4	-0.022399
CAPZA1	-0.022392
LARP1	-0.022321
CREBBP	-0.022308
EFNB2	-0.022290
NDUFV1	-0.022286
CTTN	-0.022188
GJA1	0.022181
THBS1	-0.022181
SPTSSA	0.022083
CACHD1	-0.022057
CCT3	-0.021997
NOP10	0.021914
NUDT19	0.021899
ERGIC3	-0.021782
TXNDC5	-0.021773
MFAP2	-0.021767
COL4A2	-0.021692
CFDP1	-0.021685
ECT2	0.021677
TGIF1	-0.021660
ANXA6	-0.021640
UFC1	0.021577
WDR6	-0.021506
MTHFD2	0.021499
CACUL1	-0.021499
FDX1	0.021446
SMARCA4	-0.021422
ANKRD1	-0.021414
SEC13	-0.021389
LSM3	0.021365
HMGN1	0.021343
COPA	-0.021201
SOCS2	-0.021177
TIMM8A	0.021098
POLR2M	-0.021087
RIN2	0.021035
UBA1	-0.020971
PLK3	0.020905
PPP1R14B	-0.020901
NDUFB5	0.020899
CSNK1D	-0.020885
RBMS1	0.020869
CCNB2	-0.020823
DDX5	-0.020820
IGF1R	-0.020792
FSTL1	-0.020725
PNRC2	-0.020711
MFSD1	-0.020665
UBC	-0.020648
VKORC1	0.020571
MAPK14	-0.020549
CUL1	0.020474
DNPH1	0.020467
ADD1	-0.020420
PTPRF	-0.020330
TXN	0.020326
MAT2A	-0.020205
PRNP	-0.020128
UBR4	-0.020115
PUF60	-0.020093
VCAN	-0.020073
YWHAH	-0.020003
RNF10	-0.019969
PTPN9	-0.019916
TMEM43	-0.019915
CCND3	-0.019908
FLNB	-0.019901
GTF2E2	-0.019891
H2AFX	-0.019886
PSMB5	0.019882
TSKU	0.019865
MRPL24	0.019863
CDC42SE1	-0.019861
UBTF	-0.019794
FKBP9	-0.019781
TMED2	-0.019775
AIMP1	0.019763
FIGNL1	0.019756
PEA15	-0.019754
DPP3	-0.019748
MSX2	-0.019716
GAS1	0.019695
CLTC	-0.019619
UBE2V1	-0.019599
CTSV	0.019599
WSB1	0.019576
TAF1D	0.019571
SEC16A	-0.019562
CLDN6	-0.019518
FPGS	-0.019472
MAPK6	-0.019460
PRPF6	-0.019452
ATXN7L3B	-0.019437
THUMPD1	-0.019432
HN1	-0.019289
HSPH1	-0.019283
PHF23	-0.019250
RNF181	0.019133
RAD21	0.019051
ST3GAL5	-0.019026
NUMA1	-0.018991
BACH1	0.018988
MCM3	-0.018966
RPL27A	0.018961
PIGX	0.018958
WDR61	0.018946
SNRPD2	0.018915
FXN	0.018911
MPC2	0.018877
TRAPPC1	0.018798
TUBB2A	-0.018796
POLR2H	0.018777
PDIA6	-0.018769
ADCY6	-0.018753
PSMB3	0.018702
RARS	0.018694
ARHGAP1	-0.018657
PLRG1	-0.018623
SENP3	-0.018562
ANXA5	-0.018558
HDAC1	-0.018529
ATOX1	0.018524
MTCH2	0.018518
CCT7	-0.018456
RRAGC	-0.018448
PSMA4	0.018445