!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	MK-886
!smiles	CC(C)C1=CC2=C(C=C1)N(C(=C2SC(C)(C)C)CC(C)(C)C(=O)O)CC3=CC=C(C=C3)Cl
!pubchem_cid	3651377
!cell_type	A549 cell line (lung cancer)
!organism	human
!end_metadata
FTH1P5	-0.162372
AMIGO2	0.160331
HSPE1	-0.159284
RPL39	-0.143024
ALDH3A1	0.131869
ND2	0.131814
RPL27	-0.123479
RPL34	-0.121289
COX3	-0.113853
S100A10	-0.109450
RPLP0	0.108470
ANXA2P2	-0.107208
EPHX1	0.106030
CFL1	0.105244
ALDOA	0.104716
RPL21	-0.100579
AKR1C3	-0.099965
RPL9	-0.098183
ERH	-0.095381
ATP6	-0.094608
AKR1B1	0.091994
FADS1	0.091883
RPL35	-0.088993
HSPB1	0.088300
RAN	-0.085979
ATF4	0.083972
PKM	0.083143
RPL30	-0.082781
SNRPG	-0.081483
RPS14P3	-0.081275
RPLP1	-0.081118
COX2	-0.080954
RPL24	-0.080025
CALM2	-0.079179
PSAT1	0.078399
ACTB	0.077369
NPM1	-0.076010
GPI	0.075605
RPL26	-0.075514
RPS3	-0.074752
ID1	-0.072483
RPL8	0.071541
ID3	-0.071373
CEACAM6	0.070989
RPS23	-0.070792
NOP10	-0.069178
NDUFAB1	-0.068779
RPS16	-0.067510
SCD	0.067424
FAU	0.065474
TUBA1A	0.064723
SRP9	-0.064617
HSPA1A	-0.063102
RPL23A	0.061861
FXYD2	0.058910
PTTG1	-0.058535
RPL7A	-0.057791
H2AFZ	-0.057524
ANXA1	-0.056645
MALL	0.056293
KRT8	0.056117
MRPL36	-0.056105
ODC1	0.056031
PFN1	0.055781
COX7A2	-0.055639
AGR2	-0.055626
SFN	0.055474
RPS13	-0.054640
BOLA3	-0.054444
TRIM16	0.054066
CA12	0.053999
MYL12B	-0.053969
RAB10	-0.053687
AKR1B10	-0.053669
CD63	0.052884
RPS25	-0.052295
EEF1G	0.051937
SLC3A2	0.051937
EEF1B2	0.051466
ALDH2	0.051247
DBI	0.051109
MSMO1	0.050693
NDUFA4	-0.050643
FDPS	0.050564
PPIB	0.050060
LGALS1	0.050024
RPS19	-0.049995
RPS7	-0.049686
PRDX4	-0.049278
RPS8	-0.048988
HSP90AA1	-0.048698
ECH1	0.047835
PPIA	0.047760
G6PD	0.047663
DYNLL1	-0.047341
TALDO1	0.046972
UQCRC1	0.046905
HMGB1	-0.046616
RARS	-0.046506
SLIRP	-0.046449
CDC25B	0.046292
TMA7	-0.045478
RPS3A	-0.045165
ERP29	0.044914
RPL19	-0.043884
GLA	-0.043884
RPL6	-0.043416
PGAM1	-0.043345
PRDX5	0.042981
RPS27A	-0.042709
SPP1	0.042689
RBCK1	0.042480
SNRPD2	-0.042461
ACTG1	0.041962
KIAA0101	-0.041851
SUMO2	-0.041511
PCNA	-0.041367
MSN	0.041339
S100A16	0.041243
SLC7A5	0.041109
S100A11	0.041074
ASNS	0.040843
P4HB	0.040646
MIF	-0.040171
FDFT1	0.039926
COPS5	-0.039848
GPX1	0.039737
YBX1	0.039406
ARPC2	0.039161
NDUFB1	-0.038867
MALAT1	-0.038614
LDHA	-0.038595
CD24	0.038447
ID2	-0.038299
HSPA8	-0.038128
RPL32	-0.038079
RPL3	0.038033
BTF3	-0.037748
SPINT2	0.037706
TRIB3	0.037666
IDH1	0.037628
RPS2	0.037484
SLC25A6	0.037458
CLIC1	0.037366
C20orf24	0.037116
RPL28	-0.037026
NPTN	0.036862
ATP5B	0.036680
RPL18	-0.036627
SRXN1	0.036563
MRFAP1	0.036544
PTGES3	-0.036503
ALDH1A1	-0.036386
SPCS1	-0.036171
DKK1	-0.036060
S100P	0.035963
RPL11	-0.035485
UBB	-0.035404
PTMA	-0.035341
RPL10A	-0.035319
PSMA4	-0.035230
PLS3	-0.035141
PSAP	0.034813
RPL5	-0.034527
RPS24	-0.034428
C14orf166	-0.034327
SLC22A18	0.033941
TOP2A	-0.033750
HNRNPH1	-0.033557
CERS2	0.033520
CAV1	-0.033502
PABPC3	0.033311
RPS4X	0.033306
ATP5J	-0.033256
CDKN3	-0.032596
CHCHD2	0.032426
COX5A	-0.032295
FAM96B	0.032277
MRPL51	-0.032136
GPX2	0.031849
IAH1	-0.031664
ATP5G3	-0.031542
UQCRFS1	-0.031534
PSMG2	-0.031409
COX6B1	-0.031379
H3F3B	-0.031266
EIF4A3	-0.031201
USMG5	-0.030918
KPNA2	-0.030807
TOMM5	-0.030596
RPL27A	-0.030524
TPI1	0.030445
HSBP1	-0.030340
GARS	0.030089
PPP1CB	-0.030018
EIF6	0.030000
YWHAE	-0.029979
TPT1	0.029931
PFKFB3	-0.029927
RPS10	-0.029905
JTB	0.029642
TM4SF20	0.029274
ANXA5	0.029251
TUBB	0.029200
ATRAID	-0.029082
PBK	-0.029077
NDUFA1	-0.029076
NGRN	0.029024
PRR13	0.029018
INSL4	-0.028922
RPL36A	-0.028828
SLC7A7	0.028805
C12orf75	0.028765
SNHG5	0.028716
COX7C	-0.028637
RCN1	0.028616
KRT81	0.028571
CREG1	0.028477
PABPC1	0.028386
DAD1	-0.028351
LASP1	0.028287
FTL	-0.028284
RABAC1	0.028248
ATP5I	-0.027896
PSMB6	-0.027842
DNAJA1	-0.027828
GSTP1	-0.027763
ANXA4	0.027760
DUT	-0.027614
NSA2	-0.027519
EEF2	0.027515
CYP51A1	0.027387
KRT18	-0.027343
TXNRD1	0.027250
RPL22L1	-0.027148
MYL6	-0.027126
MRPL33	-0.027032
UBA2	-0.026858
RPS21	-0.026660
UCHL1	0.026623
NEDD8	0.026583
SSR4	0.026323
ANAPC11	-0.026316
CHCHD10	0.026143
DHCR7	0.025827
BANF1	0.025820
GABARAP	-0.025756
STEAP1	0.025745
CST1	0.025726
TUBA1C	0.025678
RPS20	-0.025670
RRM2	-0.025651
UQCRH	-0.025643
DPYSL2	0.025538
ATP5C1	-0.025376
SNRPF	-0.025296
MDH1	-0.025271
ADM	-0.025177
NOP58	0.025146
CEBPB	-0.025069
TRIM28	0.024938
HINT1	-0.024751
MTHFD2	0.024692
NME7	-0.024631
RPL13	0.024579
TM4SF4	0.024548
NDUFB9	-0.024547
COX6C	-0.024481
MRPS24	-0.024047
ABCC2	0.023891
EIF3K	-0.023866
TGFBI	-0.023849
STUB1	0.023826
SNHG19	-0.023815
UFC1	0.023790
CMC2	-0.023598
HSPA5	-0.023591
CAPNS1	0.023528
RPS15A	-0.023525
ATP6AP1	0.023487
DDIT4	0.023355
TMSB10	0.023336
CYP24A1	-0.023336
DEK	-0.023245
TMEM14B	-0.023231
UBE2C	-0.023123
CRIM1	-0.023094
LAPTM4A	0.023023
YWHAG	0.023000
BSG	0.022942
CKS2	-0.022900
PSMA6	0.022781
UBE2T	-0.022735
DUSP1	-0.022647
PTPLAD1	-0.022573
FBL	0.022501
ITGAE	-0.022428
RTN4	-0.022292
AKR1C1	-0.022241
NARS	0.022054
RPS26	-0.022036
SNX17	0.021978
LBR	-0.021826
INSIG1	0.021792
SF3B6	-0.021765
FTH1	0.021740
TCEB1	-0.021547
HMGCS1	0.021478
NME1	0.021432
SSB	-0.021413
UBA52	-0.021401
S100A4	-0.021351
ASS1	0.021221
C15orf61	-0.021029
RPL23	-0.021018
SLC7A11	0.020941
POLR2I	-0.020883
CXCL5	0.020849
GBE1	0.020715
TAX1BP3	-0.020707
CYCS	-0.020669
HSP90AB1	-0.020666
TMEM258	-0.020643
PON2	-0.020636
DDX5	-0.020611
PTGR1	-0.020609
GNG11	0.020529
ACLY	0.020433
MGST1	0.020400
RPL38	-0.020288
KDELR1	0.020250
CCT3	-0.020214
PGRMC1	-0.020072
HNRNPA1	-0.019973
C12orf57	-0.019926
PGD	0.019789
TMEM14C	-0.019738
MARS	0.019724
ACADVL	0.019678
CYC1	0.019601
KRT10	-0.019560
NPC2	0.019539
CTSL	0.019462
TXNDC17	-0.019413
GOT2	0.019395
RPL37A	-0.019374
KYNU	0.019299
NDUFB3	-0.019208
SEC13	0.019169
EGR1	-0.019159
TM4SF1	-0.019158
RPS6	0.019082
RPL36AL	-0.018900
HIF1A	0.018857
NUCKS1	-0.018832
DPM1	-0.018804
ARPC1B	0.018749
RPN1	0.018655
GNG5	-0.018642
ATP5G1	-0.018609
POLR2G	0.018601
IGFBP6	0.018601
GNG10	-0.018508
LCN2	0.018425
MIR21	-0.018360
MPLKIP	-0.018338
ALDH3A2	-0.018309
AKR1C2	0.018306
RAD21	-0.018293
ENO1	-0.018252
RPS17	-0.018220
UQCRB	-0.018208
EIF4EBP1	0.018207
EIF2S3	0.018205
RPL14	-0.018186
GGT1	0.018169
CRYZ	-0.018144
GLO1	-0.018098
FGL1	0.018077
PSMA2	-0.018045
H1F0	0.017958
MRPL17	-0.017958
HUWE1	0.017930
DHX15	-0.017866
SQRDL	0.017861
PSMB5	0.017774
RPS12	-0.017774
ARPC1A	0.017773
MAGEA6	0.017751
PRDX1	-0.017646
GJA1	-0.017633
NDUFB5	-0.017631
ATP6V0D1	0.017601
SUMO1	-0.017583
EIF3M	-0.017531
LTA4H	-0.017530
CRIP1	-0.017506
TMEM97	0.017472
LINC00116	-0.017451
EMP3	0.017444
DDOST	0.017397
ATP5H	-0.017381
SUCLA2	0.017372
NDUFB4	-0.017370
CBWD1	-0.017339
TKT	0.017337
APOA1BP	0.017288
MTUS1	0.017246
NCKAP1	-0.017212
PTS	-0.017209
RPP25L	0.017194
ACTL6A	-0.017145
SEC61B	-0.017056
PHGDH	0.016993
C1QBP	-0.016990
SRSF2	-0.016963
CD81	0.016957
HERPUD1	0.016928
NCL	-0.016924
NDUFB10	-0.016882
LRRC75A-AS1	0.016821
MLPH	0.016761
NUSAP1	-0.016727
KIF5B	-0.016705
NACAP1	-0.016668
HSPA2	-0.016664
POLR2L	-0.016613
PHB2	-0.016567
AARS	0.016544
ATP5J2	0.016534
HNRNPA2B1	-0.016524
IDI1	0.016521
CEP55	-0.016427
SRSF7	-0.016408
SEC11A	-0.016406
SLC1A5	0.016255
KPNB1	-0.016201
PRPF40A	-0.016142
ZNF706	-0.016067
SNRPB2	-0.016017
KLF10	-0.016010
PIR	-0.015996
SLBP	-0.015900
BLVRB	0.015896
SLC4A2	0.015853
MYL12A	-0.015844
MAD2L1	-0.015834
CS	-0.015814
TRAPPC1	0.015809
VBP1	-0.015793
LINC00520	-0.015776
SPPL2A	0.015773
HLA-A	0.015760
SNRPD1	-0.015739
AP2M1	0.015710
ATP5E	-0.015705
CBX1	-0.015653
SHCBP1	-0.015602
RCN2	-0.015558
ATOX1	-0.015528
FKBP1A	0.015427
XPOT	0.015420
GPD1L	0.015385
GGH	-0.015374
CHMP2A	-0.015354
HGD	0.015267
TJP1	-0.015262
PRR11	-0.015202
ERRFI1	-0.015160
ISG15	0.015160
GPAA1	0.015154
NUP37	-0.015117
HSD17B12	0.015054
CHP1	0.015028
EPS8	0.015014
HNRNPR	-0.014973
ANXA3	0.014970
PLP2	-0.014903
RPL37	-0.014885
POMP	-0.014860
GCNT3	0.014829
COX5B	0.014812
LYSMD2	-0.014787
VMP1	-0.014776
ABLIM1	0.014761
PNMA1	0.014750
LACTB2	-0.014742
GBAS	-0.014692
CDIPT	-0.014656
GHITM	0.014624
SDC1	0.014606
HLA-C	0.014602
RPS29	-0.014568
RPA3	-0.014559
RPL29	-0.014523
C19orf33	0.014505
DDRGK1	0.014497
LRP11	0.014485
DHCR24	0.014465
EEF1D	0.014448