!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 5 Hour
!organism	rat
!end_metadata
PDK4	0.279076
MGP	0.266894
TRIM63	0.223095
GLUL	0.216358
COX2	-0.196080
ACTN2	0.184330
RHOB	0.155285
TRIM54	0.150155
LCN2	0.143018
TSC22D1	0.136432
TCAP	0.136063
NDUFB9	-0.127954
ERRFI1	0.124973
UBC	0.120336
TXNIP	0.114368
ZFP36	0.108559
EIF4EBP1	0.103305
UCP3	0.094317
HSPB6	-0.093561
XDH	0.092891
KLF9	0.091583
CYCS	-0.086713
CLU	0.086163
MAPK14	0.084957
HSPB1	0.084059
COL3A1	0.081054
IFITM3	0.080702
COL1A2	0.079925
ND5	-0.079433
TUBA1A	-0.078826
COX3	-0.078126
NFKBIA	0.077904
TPT1	-0.075508
NR4A1	0.073187
CEBPD	0.073019
CYC1	-0.070944
CEBPB	0.070916
DYNLL1	-0.070621
NDUFS7	0.070134
MAP1LC3B	0.069804
MYL12B	-0.069431
HSPA8	-0.069316
LDHB	-0.064704
CHRNA1	-0.064276
NDUFB4	-0.062736
PPP2R5A	0.062653
SLC3A2	0.062340
SVIL	0.061723
CRYAB	-0.060947
JUNB	0.059100
ND2	-0.058976
MYL2	-0.058573
COL1A1	0.058017
TNNT3	-0.057647
CA3	0.057168
CD63	-0.055837
SGK1	0.055588
NDUFA5	-0.054058
RPLP0	0.053861
DNAJB5	0.053039
COX7A2	-0.052714
PTP4A1	-0.051311
RPS27L	-0.051017
SDC4	0.050932
CFB	0.050836
PABPC4	0.050626
LGALS1	-0.049935
KLHL41	-0.049901
DDX3X	0.049681
MYF6	0.049644
NDUFA4	-0.048676
ATP6	0.047120
RPLP2	-0.047084
LAMC1	0.046394
GRB10	0.046181
ACADL	-0.045851
CTSV	0.045461
RRAD	0.044814
MYADM	-0.044316
CBFB	-0.043963
APOE	-0.043617
ATP5B	0.043388
SLC25A5	0.043012
ATP2A1	0.042993
EEF1A2	-0.042221
COX7B	-0.041729
MGST2	0.041103
CTSS	0.040615
B2M	0.040510
AQP1	0.040271
YWHAH	0.040230
ITGB1	0.040001
MYL3	-0.039998
TUBA1B	-0.039897
NME2	0.039221
RPSA	0.039162
COL5A2	0.038834
PPIA	-0.038525
MYH6	0.037964
ND4	-0.037080
ATP1B1	-0.037040
PSAP	0.036835
PCBP4	0.036598
ACAA2	0.036462
DES	0.036254
RPL39	-0.035984
ATP5G1	0.035844
SEPW1	-0.035375
RAB10	-0.035107
SCN1B	-0.035085
CYTB	-0.035056
PDHA1	0.034772
ENO1	0.034572
MPC1	-0.034542
MYBPC2	0.034357
ACTB	-0.034240
ND1	-0.034215
LYZ	0.033982
GABARAPL2	-0.033938
PSMD2	-0.033877
PIM3	0.033874
PLA1A	0.033791
PECAM1	0.033700
RPL6	0.033392
ENO3	-0.033352
NDUFV2	0.033345
PPP1CB	0.032769
POSTN	0.032327
BTG1	0.032209
MYOD1	-0.031925
RPL26	-0.031879
TMA7	-0.031705
CKMT2	0.031467
MYBPC1	-0.031462
WIPF3	0.031415
NDUFB6	-0.030852
FTL	-0.030783
GSTP1	-0.030781
BTG2	0.030672
SCHIP1	0.030651
LDHA	0.030167
NEU2	-0.030118
AMPD1	-0.030086
UQCRC2	-0.030074
TUBA1C	0.029992
UBE2G2	0.029985
PGAM2	-0.029461
ACTG1	-0.029403
TCP11L2	0.029384
FABP3	-0.028983
ASB2	-0.028774
RAB5B	-0.028660
EEF2	0.028612
TXN2	-0.028548
KLHDC3	0.028526
PSME4	0.028458
TCEB1	-0.028407
LDB3	0.028264
RPS25	-0.028260
FTH1	0.027817
TIMP1	0.027568
PFKM	0.027522
RPL23	0.027469
ASPH	0.027402
ANGPT2	0.027120
MYOG	-0.026920
RPL27	-0.026900
RHEB	0.026696
TUBA4A	-0.026605
RPS9	0.026221
ACTA1	0.026195
PGAM1	0.026192
SDCBP	0.026113
PGM2	-0.025566
ATP5G2	0.025547
DBP	-0.025513
VDAC1	-0.025434
IDH2	-0.024785
PPARD	0.024626
TIMP2	0.024534
DUSP1	0.024435
SPARC	0.024384
NDUFA3	-0.024219
EMP1	-0.024165
SERBP1	-0.024064
TIMM17A	-0.024059
LOX	0.024048
GPX4	-0.023986
PDK2	-0.023985
FAU	-0.023855
COX5A	0.023789
SERPINE1	0.023751
RPS17	-0.023652
ANXA5	-0.023640
SPRY1	0.023621
PFKFB3	0.023610
ARNTL	0.023468
LYVE1	0.023180
VEZF1	-0.023124
NUDT4	-0.023109
NDUFA9	-0.023067
PSMD11	0.022955
MAPK6	-0.022921
ATP6V1F	-0.022918
CACNG1	-0.022914
MAFK	0.022873
ECE1	0.022794
GPX1	-0.022597
ATP1A2	0.022533
COX8A	-0.022390
GSTM1	-0.022379
CITED2	-0.022284
CSDE1	-0.022279
PTP4A2	-0.022198
NDUFC1	-0.022069
SLC2A4	0.022051
GNPAT	0.022010
HRAS	-0.021987
CXXC5	-0.021890
PPP1R1A	0.021566
MAPK3	-0.021422
MYL12A	-0.021415
DAPK2	-0.021197
H1F0	-0.020948
MMP14	-0.020758
PRDX1	-0.020593
SLC6A8	-0.020448
RPL15	-0.020384
RPL10	0.020366
GRINA	0.020349
SLC25A3	0.020340
MYH1	-0.020298
ATP6V0C	0.020295
LMNA	-0.020265
MYOC	-0.020177
HMOX1	0.020157
NDUFB10	0.020094
MLLT3	-0.019979
S100A4	-0.019973
MYL1	-0.019927
PTPN3	-0.019881
RPS6	0.019689
PFKFB4	0.019533
KCNC4	-0.019122
HADHB	-0.019091
RPS15	-0.019055
RPL4	-0.019040
PPP1CA	-0.019017
HIBADH	-0.019015
HSPD1	-0.018991
CD74	-0.018933
PMEPA1	-0.018908
RBBP7	-0.018854
SDHA	-0.018768
HK2	0.018685
EGR1	-0.018680
PLAGL1	0.018675
SIRT2	-0.018672
ARL4A	0.018527
IFRD1	0.018510
GOT2	0.018458
NDUFA6	-0.018445
IDH3G	0.018429
TPI1	-0.018366
CTDSP1	-0.018339
LUM	-0.018232
NRP1	-0.018224
SLC28A2	0.018210
TFRC	-0.018200
CRISPLD2	0.018178
ANXA2	-0.018128
PKM	0.018127
RPS15A	-0.018056
AP2M1	-0.017942
BHLHE40	-0.017878
ATP5F1	-0.017784
BCL2L1	0.017764
PKIA	-0.017762
TNNI2	0.017712
ALDH2	-0.017664
POMP	-0.017608
GADD45A	0.017565
AKR1A1	-0.017563
PXN	0.017465
SLC41A3	0.017453
UBE2B	-0.017451
TJP1	-0.017436
LITAF	0.017404
CPA1	-0.017363
CYP27A1	0.017338
NDUFB2	-0.017331
NCL	0.017329
SCARB1	-0.017292
ARF1	0.017291
CNBP	-0.017285
CLTC	-0.017251
HSPE1	-0.017228
SOD1	-0.017217
SEPP1	-0.017212
UQCR11	0.017113
NEXN	-0.017072
PIK3CD	0.017010
PDE4B	0.016954
OAZ1	0.016877
PSMA6	0.016807
APEX1	0.016780
ATF3	-0.016629
DNM1	-0.016578
CLCN1	-0.016479
TSPO	0.016455
INSIG1	0.016452
PF4	-0.016423
RPL8	0.016355
DNAJA2	-0.016278
UBXN1	0.016274
PTPN1	0.016266
EIF3B	0.016240
GNG5	-0.016199
MRFAP1	0.016177
IRS1	-0.016140
HBP1	0.016129
NOL3	-0.016108
GPX3	-0.016085
CDC42EP3	-0.016083
ZFP36L1	-0.015829
NUCB1	0.015826
SDC2	-0.015822
PEBP1	-0.015797
HIGD2A	0.015500
EIF4A2	0.015439
SLC25A4	-0.015417
GPD1	0.015406
TRAPPC6B	0.015375
RPS8	0.015325
HSP90AB1	-0.015283
ATP2A2	0.015103
H2AFZ	-0.015043
LGALS3	0.015034
JUP	-0.014991
RPS13	0.014958
SQSTM1	0.014830
G3BP2	0.014775
ANKRD1	-0.014729
PVALB	-0.014620
SLC37A4	0.014598
LPL	-0.014586
YBX3	-0.014584
SSR3	0.014578
CCNG1	0.014514
MEOX2	-0.014491
BCAT2	-0.014438
MYH7	-0.014433
PTTG1IP	0.014293
F2R	-0.014278
IGFBP3	0.014246
CSNK1D	0.014236
IRF7	0.014203
RPL9	-0.014141
C1QB	0.014103
MYCBP2	0.014050
RPL14	-0.014046
RPL19	0.014025
PRNP	-0.014010
ITM2B	-0.013976
MAP2K1	-0.013975
BLMH	-0.013967
ANAPC16	0.013900
SPARCL1	-0.013888
MDH1	-0.013876
COX6A2	0.013863
GRN	-0.013852
DACT2	-0.013808
RPL22	0.013785
NPM1	0.013753
RPL10A	0.013751
MYC	0.013745
PSMB4	0.013718
OXR1	-0.013595
CAPG	0.013520
COX7A2L	-0.013513
CASQ1	0.013486
DECR1	-0.013454
ME1	-0.013425
OAT	0.013420
RPL37	-0.013396
RPL18A	0.013365
ACSL1	-0.013331
NFIB	-0.013325
MYL4	-0.013298
TUBB	-0.013297
AUH	0.013276
TUFM	0.013272
AKAP1	0.013268
AK1	0.013264
GNB2L1	0.013256
APH1A	-0.013230
TXNRD1	0.013229
DHRS7C	-0.013197
DTD1	-0.013161
TLE1	-0.013092
PSMB5	-0.013041
FMO1	0.012997
CSRP1	-0.012945
ERCC1	0.012928
RPL3L	-0.012892
PSME2	0.012819
PPM1A	-0.012748
AHNAK	0.012745
ZNRF1	0.012713
EGLN3	-0.012706
VEGFA	0.012701
MYL9	-0.012637
LTBP1	-0.012622
CD81	-0.012577
P2RY2	-0.012549
DAB2	0.012548
CRP	-0.012533
TOMM20	-0.012486
SNN	-0.012430
RPL18	0.012355
ALDH1A1	-0.012261
GNG11	-0.012184
CSRP2	0.012184
CALU	0.012176
TNNC2	0.012175
RPS23	-0.012164
CAPN3	-0.012155
ATP9B	-0.012120
PPP1R15A	0.012001
SERINC5	0.011961
RRAGA	-0.011947
PLEKHA1	0.011930
PAPSS1	-0.011929
BIN1	-0.011895
CTSB	0.011868
MYBPH	-0.011818
IFNGR1	0.011815
HDLBP	0.011812
PFN1	-0.011763
RPL7A	0.011746
NRARP	-0.011689
RNPEP	-0.011606
COX6A1	-0.011606
SPP1	0.011593
MYH2	-0.011584
DCAF6	-0.011557
RXRG	-0.011538
BNIP3L	0.011455
RPL21	-0.011427
PAIP1	-0.011362
NEB	-0.011321
DDIT3	-0.011303
IDH1	-0.011278
MGLL	-0.011214
AGO2	0.011194
JTB	-0.011180
RPN2	0.011171
TNNI1	0.011169
RPS14	0.011160
ATG13	0.011138
GABARAP	-0.011136
ATP1B3	-0.011122
ACLY	0.011109
NDUFAB1	0.011051
TIMM23	-0.011037
FLNC	0.011010
TGFB1	-0.010990
PCNA	-0.010990
UGDH	0.010985
SLC25A17	0.010971
UACA	-0.010944
PRKAR1A	-0.010931
BSG	0.010912
GNB2	-0.010876
GAS6	0.010866
PNRC2	-0.010855
NDUFB3	-0.010835
ATP5J	-0.010823
CANX	-0.010821
RPS3	0.010819
EMB	-0.010736
ALDOA	-0.010663
QDPR	-0.010660
CD48	-0.010652
PSMB2	-0.010648
HP	0.010648
ACADVL	0.010627
S100A10	0.010627
NDUFS4	-0.010626
CD200	-0.010606
CYP7B1	0.010584
EIF2B4	0.010547
NR1D2	-0.010533
NFKB1	0.010485
EIF5	0.010481
CST3	-0.010440
IGF2	0.010409
HMGA1	-0.010340
SERPING1	0.010296
GMFB	-0.010276