!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 72 Hour
!organism	rat
!end_metadata
COX7A2	-0.227377
NDUFB9	-0.216265
TNNT3	-0.209597
ATP2A1	0.185589
PPP2R5A	0.151987
ACTN2	0.148586
NDUFS7	0.145327
MYBPH	0.143223
CYC1	-0.130266
COX2	-0.130201
COX1	-0.126489
MGP	-0.122668
SLC16A3	0.116764
ND5	-0.109300
ASB2	-0.104638
MDH1	0.101120
RPL39	-0.100552
PABPC4	0.097372
MPC1	-0.097069
TNNC2	0.095905
RPLP0	0.093784
ATP5F1	-0.091732
BIN1	0.090354
CYTB	-0.089933
NEXN	-0.088702
NDUFV2	0.088467
PDK4	-0.088260
COL1A2	0.086964
JPH2	0.086818
SDHA	-0.086690
FLNC	0.086586
TPI1	0.084778
ENO3	-0.084571
COL1A1	0.083632
PFKM	-0.082724
PTP4A2	0.082179
AMPD1	-0.081499
EIF4A2	-0.081118
HSPB1	0.079172
UBC	-0.078673
COX6A2	0.078322
CA3	0.073717
ATP6	-0.071156
TRIM54	-0.071045
H19	0.068974
ND2	-0.067963
MDH2	0.067896
OAZ1	-0.067805
EEF2	-0.066408
RPL22	-0.065722
CD63	-0.065678
PFN1	0.064489
NR1D1	0.062564
PGAM2	0.061933
ACAA2	-0.061885
PVALB	0.061775
IGF2	0.060748
GLUL	-0.060632
LGALS1	0.060241
CHRNA1	-0.060235
UCP3	-0.059941
ACTG1	0.059707
MYLPF	0.059489
RPS26	0.058617
ALDH1A1	0.058328
NDUFA3	0.057365
CKMT2	0.057264
PSME4	-0.056196
NDUFB3	-0.056022
MYL1	0.055579
ATP5G1	-0.055360
FABP3	-0.055067
SLC41A3	0.054548
KLHL41	-0.054026
MYL3	0.053889
NPHP1	0.053785
CACNA2D1	0.053748
LPL	-0.053460
NDUFA5	-0.053450
VIM	-0.052801
UQCRFS1	0.052239
NME2	0.049907
TNNI2	0.049368
LUM	-0.049260
PPIA	-0.048025
NDUFA8	0.047746
TFRC	0.046830
TXNIP	0.046407
PPP1R1A	-0.046124
SEPW1	-0.045963
SLC37A4	0.045772
H1F0	-0.045751
PDHA1	0.045647
TXN2	0.045331
CNBP	0.045166
EEF1A2	0.045153
TUBA1B	0.045145
FLOT1	0.045075
COX4I1	0.043693
COL3A1	-0.043590
LDHB	-0.043245
BSG	0.043129
GPX4	0.042263
TMBIM6	-0.041951
MAP1LC3A	0.041514
CD36	-0.041288
RPL6	0.040934
TCAP	0.040163
HSPE1	0.039930
ACADL	-0.039576
ATP1A2	-0.039006
RPL7A	0.038796
GOT1	0.038785
RPS9	-0.038608
CACNA1S	-0.038232
RPL26	-0.038130
ACSL6	0.038095
MYBPC1	-0.037898
PKM	0.037832
COX8A	0.037646
NDRG2	-0.037015
COPZ1	0.036729
RPL10A	0.036468
TIMM17A	0.036212
LDHA	0.036113
FKBP3	0.036068
HIGD2A	0.036022
LDB3	0.035889
RPS4Y1	-0.035651
MYL12B	-0.035211
RAB10	-0.035073
NDUFB2	0.035004
ALAS1	0.034928
NDUFA4	-0.034843
FTL	-0.034561
PSME2	0.034377
SCD	0.034078
NDUFB10	0.034050
ATP5H	-0.034005
MRFAP1	-0.033733
NDUFB6	-0.033647
RPS11	0.033611
IDH2	0.033466
DNAJB5	0.033134
RPS16	0.032453
NDUFA9	-0.032382
PSME1	0.032207
ARF1	-0.032004
VPS4A	0.031599
CACNG1	-0.031543
BTG1	-0.031443
ECH1	-0.031184
DYNLRB1	0.031131
TSPAN8	-0.031125
HADHB	-0.031029
SET	0.030856
RPL24	-0.030833
CTBP1	0.030231
TIMP2	0.030133
NDUFB8	0.029955
HSD11B1	0.029780
DCAF6	0.029756
SOD2	-0.029580
IFITM3	-0.029397
PARK7	-0.029291
POSTN	-0.029212
JAK1	0.029111
MYL9	0.029007
GPR182	0.028739
TOMM20	0.028715
IGFBP6	0.028655
CST3	0.028610
YBX3	-0.028235
PAICS	0.028104
COX5A	0.028038
GPX1	0.028006
CS	-0.028003
ATP5J	-0.027880
RAF1	0.027879
UQCRC2	0.027566
TNFRSF1A	-0.027274
RPS3	0.027197
MFGE8	0.027179
SDHAF2	0.027136
RPL3L	0.026977
FXYD1	-0.026939
CHRNB1	-0.026937
GRM7	0.026859
UBE2J2	0.026851
PRKAR1A	-0.026756
SNRPB	-0.026699
CTSV	-0.026559
RPL10	-0.026531
ZFP36L1	-0.026434
EIF2B4	0.026336
RAB12	-0.026321
TMEM59	-0.026270
RPL37	-0.026252
AHNAK	-0.025682
CYCS	-0.025595
PSMD2	-0.025470
CDC37	0.025416
PSMB3	-0.025405
CTSD	-0.025221
G0S2	0.025195
ATP5O	-0.025171
NDUFAB1	-0.025116
AQP1	-0.025016
FABP6	0.024912
ACADS	0.024877
GPD1	-0.024801
DNAJA1	-0.024614
COX3	0.024576
RPL31	0.024571
RPS15	0.024569
MYL2	-0.024548
PYY	0.024500
SPRY1	-0.024363
RPL28	0.024315
ATP5D	0.024233
PPP2R1A	-0.024224
ALPL	0.024092
ASPH	0.024049
SLC25A4	0.024021
VCP	-0.023924
PSMB5	-0.023896
KIF13A	0.023796
ATP5B	0.023781
ITM2B	-0.023750
CRYAB	-0.023575
POMP	0.023532
HIBADH	-0.023524
SH3KBP1	0.023334
HDLBP	0.023273
RPS8	-0.023204
RPS17	-0.023173
RPL15	0.023098
SEC62	-0.023073
BCAT2	-0.022916
CYB5R1	0.022910
ACADSB	-0.022903
SPARC	-0.022714
DARS	0.022700
MYL4	-0.022554
CPT1B	-0.022525
THBS4	0.022454
SYS1	0.022299
CANX	-0.022238
UQCR11	0.022218
MAPK6	0.022206
PTOV1	0.022096
YWHAG	0.022075
PRDX3	-0.022046
JUN	-0.021975
CKM	-0.021957
CCNG1	0.021919
MMP14	-0.021895
TUBB4B	0.021878
FABP4	-0.021816
UBE2B	-0.021805
PSMC2	-0.021746
TUFM	0.021690
TSC22D1	0.021634
TUBA4A	0.021609
HSPA4	0.021569
RPL35	0.021482
RPL13A	-0.021464
USP19	0.021451
GRB10	-0.021428
YWHAZ	-0.021340
OXR1	-0.021334
MATR3	-0.021171
EIF4EBP1	-0.021116
UACA	-0.021056
NUDT4	-0.021055
ACADVL	-0.021043
LGR4	0.021031
DAPK3	0.020958
PSMB2	0.020947
UCP2	0.020901
LGALS3BP	0.020889
SPARCL1	-0.020668
ACTA2	0.020607
RPL12	-0.020601
MPST	0.020592
PDGFA	0.020544
NSFL1C	-0.020518
RPL11	-0.020444
VEZF1	0.020414
EIF2B2	0.020404
C11orf73	0.020333
BTG2	-0.020227
UBR5	0.020092
ITGB1	-0.020082
SIRT2	-0.019939
TRAPPC6B	0.019938
RPL9	0.019927
YWHAH	0.019836
PPP3R1	-0.019835
DLK1	-0.019683
MAPKAPK3	0.019602
CLU	0.019587
PHKG1	-0.019566
GAPDH	0.019551
RPL19	0.019523
YWHAB	-0.019461
CHAD	0.019455
APH1A	-0.019432
PSMB4	0.019286
UQCC2	0.019281
CAPNS1	0.019212
RPS13	0.019169
ACADM	0.019137
NPM1	-0.019132
NDUFC1	-0.019011
GOT2	0.018998
RPL14	0.018925
TMEM255B	0.018924
MYBPC2	0.018877
NAA15	-0.018815
GRINA	-0.018811
JUP	0.018748
TAF6	0.018628
CAP2	0.018593
CAPZA2	0.018544
SH2B2	0.018524
BAG6	0.018410
RBBP7	-0.018379
PNRC1	-0.018377
DLAT	0.018124
ALAS2	0.018027
EIF3D	0.017829
COX6A1	0.017826
KLF4	-0.017783
TAF10	0.017646
SEC61B	0.017628
LAMTOR1	-0.017514
GSTA5	-0.017514
CAV3	0.017480
CLCN1	-0.017472
KLC1	0.017427
COL15A1	0.017371
S100A4	0.017302
ATP6V1D	-0.017301
PDE4C	0.017148
PCNA	-0.017133
CXCL14	-0.017124
TOMM6	0.016996
ANKRD1	0.016969
KCNJ11	0.016917
TNNI1	-0.016899
RXRG	0.016853
FGF10	0.016743
PSMA5	-0.016684
PYGM	-0.016620
MLLT3	-0.016610
PTGER3	0.016562
RPL3	-0.016462
HSP90AA1	-0.016389
SNRNP70	0.016381
ANXA4	-0.016206
RPSA	-0.016163
GRHPR	-0.016133
CHURC1	-0.016120
CASQ1	-0.015990
TMEM126B	-0.015970
RPL27	0.015964
IGFBP5	-0.015945
ALDH6A1	-0.015901
EMP1	-0.015878
MYH6	-0.015870
GNAS	0.015843
NRARP	-0.015770
GSTP1	-0.015767
XPO7	0.015754
ALDOA	-0.015638
PDHB	0.015596
KANK2	0.015494
SUB1	-0.015475
AIFM1	0.015448
CD48	-0.015448
RRAGA	0.015417
ATP1B1	0.015395
SGK1	0.015378
ID3	-0.015302
NEK7	0.015292
FGGY	-0.015279
TXNRD1	-0.015220
RABAC1	0.015197
RNF4	-0.015100
CSRP1	-0.015096
MAP2K2	0.014865
SMC1A	0.014789
ENO1	0.014779
UBXN1	-0.014751
DUSP1	0.014748
PRDX1	-0.014725
CYHR1	-0.014655
NCL	-0.014608
GNG5	0.014434
EEF1G	0.014426
TALDO1	0.014425
CYB5A	-0.014401
TCEB1	-0.014394
CD74	-0.014374
TIMM23	0.014352
HNRNPU	-0.014352
PMEPA1	0.014343
PPP3CA	0.014255
HSPA8	-0.014239
KTI12	0.014234
CAMK2B	-0.014212
CDC34	0.014188
ECHS1	-0.014183
SRSF11	-0.014161
PPP1CB	-0.014129
PSMB6	0.014111
ACTB	-0.014064
IQSEC1	0.014021
DNAJB9	-0.014011
RPS27L	-0.013976
NR4A1	0.013973
REEP2	0.013962
NRBP1	-0.013940
CSDE1	0.013916
AKT1	0.013840
GSTM2	-0.013830
CGRRF1	-0.013796
ETFA	-0.013767
SLC25A3	-0.013727
PTN	-0.013718
SMPX	-0.013660
TPT1	0.013529
RPS21	0.013527
BCKDHA	-0.013516
GFM1	0.013503
RPL23	-0.013460
NAPA	0.013444
ACTA1	-0.013436
ASNSD1	0.013397
ACKR3	0.013386
GINM1	0.013345
SCHIP1	0.013309
TAP1	0.013308
PHKA1	-0.013294
TST	0.013289
ARPC5L	0.013281
MYL12A	-0.013281
PECAM1	-0.013261
KCNH3	0.013256
RPN2	0.013199
DDT	-0.013121
AKT2	-0.013021
RPL18	-0.012982
RPS25	-0.012975
USO1	0.012949
EIF4E2	0.012935
AHCY	-0.012851
H2AFZ	-0.012741
CITED2	-0.012685
SEC14L3	0.012677
MGLL	-0.012589
MAP1LC3B	-0.012523
GRB14	0.012464
IMP3	0.012457
TJP1	-0.012438
ADIPOR2	0.012427
ZFAND6	0.012419
PSMA2	-0.012376
VAMP5	-0.012375
PDK2	0.012366
ATP2A2	0.012362
PLCD4	0.012291
MYH1	-0.012234
CCT3	0.012224
CTSC	0.012188
CPQ	-0.012157
LOXL1	0.012153
CD81	-0.012133
ACTC1	0.012130
NDUFS8	0.012097
COL4A3	0.012014
AQP4	-0.011983
RPS7	0.011942
COX7A2L	-0.011936
AKAP1	0.011867
YBX1	-0.011863
FDFT1	-0.011857
ATP6V1C1	0.011845
PTBP1	0.011821
SLC6A8	0.011777
CDK4	-0.011755
TCP11L2	-0.011713
YIF1A	0.011710
CHRM5	0.011688
DECR1	-0.011671
DNAJA4	0.011666
GPT	0.011626
TXNL1	-0.011624
EIF3B	0.011588