!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	sapphyrin PCI-2050 (2.5 μM)
!smiles	CCC1=C(C2=C3C(=C(C(=N3)C=C4C(=C(C(=CC5=C(C(=C(N5)C=C6C(=C(C(=CC1=N2)N6)C)CCCOC(=O)N(CCOCCOCCOC)CCOCCOCCOC)CC)CC)N4)CCCOC(=O)N(CCOCCOCCOC)CCOCCOCCOC)C)CC)C)C
!pubchem_cid	9855235
!cell_type	A549 lung cancer cells
!organism	human
!end_metadata
COX1	-0.503656
COX2	-0.473123
ND6	0.283218
DKK1	-0.230811
UBC	-0.200344
SLC38A2	-0.182969
ND2	-0.121848
MIR21	-0.099537
HERPUD1	-0.097719
ATP6	-0.081586
IGFBP4	0.079371
ID1	-0.078351
ERRFI1	-0.067556
AMIGO2	-0.067461
ACTB	0.060696
FTL	-0.059645
RPL30	-0.058475
PKM	0.057927
PKDCC	-0.057170
NTS	-0.054689
TUBA1C	-0.054629
DDIT4	-0.053173
CEBPB	-0.052150
MORF4L1	-0.049032
BANF1	0.048479
TUBA1B	-0.048437
TOB1	-0.046055
RPS18	-0.044239
BTG1	-0.044195
MIF	-0.041958
KCNJ2	-0.041946
SLC25A5	0.040478
CFL1	0.040469
ODC1	-0.039700
RPL27	-0.039457
ALDH3A1	0.039401
BSG	0.038124
FLRT3	-0.037640
PTGES3	0.037197
TGFBR2	-0.036939
TMSB10	0.036814
MAPK6	-0.036180
CD63	-0.034680
H2AFZ	-0.033472
CDKN1B	-0.033066
EIF3E	0.032562
MAT2A	-0.031970
LINC00473	0.031418
EPHX1	0.031245
ALX1	-0.030902
TIPARP	0.030700
TNFRSF1A	-0.030543
PRDX1	0.030532
RPLP0	0.030457
PCNA	-0.030073
ANP32B	0.029944
LINC00657	-0.029905
RPL3	0.029107
NDUFA13	-0.029026
RNASEK	0.028874
TSC22D1	-0.028871
RPS13	0.028573
AHR	-0.028484
FAM107B	-0.028364
EIF1	-0.028334
TM2D3	-0.028261
PLA2G4A	-0.028027
CCNG1	-0.028018
NDUFA4	-0.027627
IRF2BPL	-0.027608
PKD1P1	0.027447
NGFRAP1	-0.027442
PFN1	0.027230
PMAIP1	-0.027048
PTPRO	-0.027007
LDHB	0.026846
NPIPA1	0.026035
MLPH	-0.025884
S100A6	-0.025861
RHPN2	-0.025751
RPS4Y1	0.025599
SNHG1	-0.025514
SNHG6	0.025369
SNHG8	-0.024897
RPS10	-0.024803
RGS2	-0.024648
TUBA1A	-0.024647
ACTG1	0.024502
GNB2L1	0.024421
OAT	-0.023593
C20orf24	0.023457
EEF1A1	0.023356
EIF2A	-0.023296
ALDOA	0.023233
SAT1	-0.023089
SGK223	-0.022672
HNRNPA0	-0.022526
RPS25	0.022519
PLK2	-0.022299
ZFAND5	-0.022217
DYNLL1	-0.022121
RPS20	-0.022097
SRSF2	-0.022020
TSPAN13	-0.022007
RPS14P3	0.021971
EIF3H	0.021754
CS	0.021746
DNAJA1	-0.021363
EIF4A3	-0.021121
PSMC6	-0.021034
C8orf4	-0.020889
LHX8	-0.020879
UQCRC1	0.020855
BAMBI	-0.020707
LAPTM4A	-0.020616
NARS	-0.020609
BLOC1S2	-0.020440
RPL41	-0.020432
CHCHD2	0.020378
DNAJB9	-0.020340
EIF4H	0.020080
HSPB1	0.020058
SLC25A3	0.020006
SMNDC1	-0.019996
MYL12B	-0.019983
SEC24B	-0.019967
RPL9	0.019939
RPL28	0.019870
NPTN	-0.019698
C14orf119	-0.019690
EDN1	-0.019599
NOP10	-0.019555
ALDH2	0.019551
SGK1	-0.019502
HSP90AA1	-0.019448
KIF5B	-0.019402
EEF1A2	0.019335
HNRNPAB	-0.019294
PRDX4	-0.019235
CYSTM1	-0.019148
RPS17	-0.019138
PSMA6	0.019123
WWTR1	-0.019019
SLC25A6	0.018955
CCT3	0.018866
GNL3	-0.018866
IMP3	-0.018853
PSAT1	-0.018790
XPOT	-0.018748
CNTN1	-0.018703
NUDT19	-0.018679
NHP2	-0.018649
FTH1	0.018614
RPL39	-0.018530
RFK	-0.018487
ZNF217	-0.018447
TGFBI	0.018424
IER5	-0.018289
ATP5G2	0.018270
PDCD10	-0.018142
RPL36	-0.018079
PABPC3	-0.018044
METTL23	-0.018025
ATP5B	0.018024
PSMD12	-0.018003
SEC11A	0.017922
PTGS2	-0.017858
RPL21	0.017822
EEF2	0.017730
VDAC2	0.017606
RNF139	-0.017552
TMEM147	0.017523
GARS	-0.017445
AHCY	0.017441
H3F3B	-0.017395
EIF4A2	-0.017393
TM4SF1	-0.017361
PFN2	0.017333
AGTR1	-0.017299
RPS3	0.017165
ANXA2P2	0.017120
RPL34	0.017091
USMG5	0.017086
SLC3A2	-0.016869
NDUFC2	-0.016778
LBR	-0.016739
COX6C	-0.016719
S100A4	-0.016656
CHMP2A	0.016594
CKS2	-0.016543
YBX1	0.016494
STEAP1	0.016452
INHBB	-0.016432
GABARAPL2	0.016379
SHC1	0.016358
NPM1	0.016304
SNRPD2	-0.016283
CLIC1	0.016257
HIF1A	0.016226
RPS24	0.016073
TBCA	-0.016063
RPL26	-0.015890
CHP1	0.015864
CHCHD10	0.015857
RND3	-0.015791
NOL11	-0.015731
EIF3D	0.015701
MRFAP1	0.015675
IGFBP3	-0.015651
RPL13A	0.015645
KRT8	0.015478
RPL23A	0.015456
TRA2B	-0.015455
MTHFD2	-0.015447
GDF15	0.015428
RPL19	-0.015373
RPS8	0.015367
DHX32	-0.015340
NONO	0.015334
CTBP2	-0.015296
COX6B1	0.015276
SEPHS2	-0.015221
RPL23	0.015209
PPP1R15B	-0.015205
TFRC	-0.015197
KPNA2	-0.015192
RPS7	-0.015191
BLVRB	0.015152
C12orf57	-0.015124
PNRC1	-0.015088
GAPDH	0.015040
RPL31	0.015024
FASTKD3	-0.015004
RPL13	0.014995
NRIP1	0.014972
MTUS1	-0.014874
ZCCHC8	-0.014853
PSMA1	0.014826
COPB1	-0.014757
TVP23B	-0.014654
OXA1L	0.014642
C5	-0.014631
NOC3L	-0.014573
SRSF1	-0.014573
AKR1C3	0.014572
NDUFA12	-0.014526
RPSA	-0.014514
POLR2L	-0.014482
MYC	-0.014468
MIR22HG	0.014466
HHEX	-0.014439
CCT2	-0.014425
RPL38	0.014418
PPIB	-0.014410
OGT	-0.014404
NME7	-0.014388
C1orf131	-0.014362
STEAP2	-0.014333
KARS	0.014269
DHX15	-0.014262
GSTP1	-0.014247
NCOA7	-0.014231
SRP9	-0.014218
HINT1	-0.014182
RPL12	0.014092
RPS11	-0.014037
KDELR1	0.013993
TMEM263	-0.013990
EFR3A	-0.013959
DHRS3	0.013958
EPDR1	-0.013955
ITGAV	-0.013821
RAN	-0.013818
PPP1CC	-0.013735
CD81	0.013702
CSTB	-0.013690
MID1	-0.013676
ENO1	0.013664
RPL18	0.013661
C9orf3	0.013616
NET1	-0.013595
COX7A2L	0.013572
SEC13	0.013543
TSKU	-0.013541
MGST1	-0.013540
NEDD8	0.013468
G6PD	0.013460
NDUFB1	-0.013458
ARCN1	-0.013448
GOLPH3L	-0.013388
VIM	0.013302
EID3	0.013259
ZBED5	-0.013232
NDUFA1	0.013156
AGR2	-0.013151
RHOBTB1	-0.013147
PGD	0.013129
CD164	-0.013121
LTA4H	0.013032
HIAT1	-0.013015
TXNIP	-0.012996
ARPC3	-0.012988
BET1	-0.012934
S100P	-0.012922
PRNP	-0.012909
ID2	-0.012898
CEBPZ	-0.012857
NNMT	0.012823
UTP3	0.012766
GPX4	0.012747
RABGGTB	-0.012743
SRP68	0.012741
GORASP2	-0.012693
LASP1	0.012690
CDK7	-0.012681
UBE2Q2	-0.012654
YWHAG	-0.012643
MKNK2	-0.012569
PSMG2	-0.012537
ACBD5	-0.012506
GLO1	0.012470
POLR2B	-0.012456
LOC100131564	-0.012394
JUND	0.012346
IPO7	-0.012345
PNPLA8	-0.012341
PDIA4	0.012297
NDUFAB1	-0.012277
SLBP	-0.012266
COX4I1	-0.012248
RPL22L1	-0.012230
SLC30A1	-0.012210
CDC25B	-0.012186
ETFB	-0.012126
NEK7	-0.012079
MIEN1	-0.012062
DDX3X	-0.012059
GCNT3	-0.012032
RPLP1	-0.012018
VPS4B	-0.012017
RPL14	0.011979
ADM	-0.011943
PDK4	-0.011854
SLC1A5	0.011833
ZC3HAV1	-0.011831
RPL35	-0.011803
DDX47	-0.011756
LUC7L3	-0.011737
HPGD	-0.011737
ACLY	0.011714
SRSF7	-0.011711
CTGF	-0.011675
CNEP1R1	-0.011663
RDH10	-0.011648
FKBP1A	0.011647
SMOX	0.011638
RPS15	0.011629
RPS27L	0.011613
ATP5G3	0.011588
SLTM	-0.011573
DSG2	-0.011523
DEK	-0.011504
PHB2	0.011475
C1orf106	-0.011462
RNF135	-0.011459
PLS3	-0.011397
RNF145	-0.011384
TFF1	-0.011383
EMC6	-0.011381
PLEKHA1	-0.011372
PDE4B	-0.011352
EIF4B	0.011331
CKS1B	0.011305
C15orf61	-0.011296
RCN1	0.011294
MSN	0.011271
ERP29	-0.011265
CCNI	0.011264
RPS9	-0.011190
MYADM	-0.011174
SRP19	-0.011170
PNMA1	-0.011157
RBM23	-0.011154
RAP1B	-0.011152
RHOA	0.011133
PDIA5	-0.011105
PARK7	-0.011103
DDX17	-0.011100
LEMD3	-0.011085
ITGB1	-0.011069
PLCXD1	-0.011063
HNRNPA1	-0.011026
TUBB4B	-0.011017
RIN2	-0.011013
TBPL1	-0.010996
MT2A	-0.010973
XRCC6	0.010966
GNG5	-0.010966
NAP1L1	0.010955
GLRX	-0.010952
CETN3	-0.010939
SCAF8	-0.010938
GTF3C6	-0.010930
SEMA4B	-0.010911
AKR1C2	0.010910
HNRNPC	0.010895
RPS12	-0.010824
LAMB1	-0.010823
EEF1D	-0.010765
ZNF146	-0.010764
HSPA13	-0.010737
RASA1	-0.010734
PRPF8	-0.010696
PON2	0.010668
CTR9	-0.010650
RPS29	0.010648
ANKRD49	-0.010644
NUFIP2	-0.010641
C1D	-0.010612
TIMP1	-0.010600
ADORA2B	-0.010596
NDUFB10	-0.010571
SUCLA2	-0.010564
PSMB5	0.010529
EEF1B2	0.010522
HADHB	0.010516
COX3	-0.010514
PCED1B	-0.010468
CIB1	-0.010467
STAM	-0.010437
GLIS2	-0.010418
B4GALT5	-0.010378
OS9	0.010367
VMP1	-0.010360
UBB	-0.010344
ACVR1	-0.010332
CEBPD	-0.010329
EIF1AX	-0.010322
GPRC5A	0.010303
HSP90AB1	0.010295
CYP24A1	0.010279
AP2B1	0.010275
PTP4A1	0.010273
FGG	-0.010252
AK3	-0.010244
GTF2B	-0.010228
LYSMD2	-0.010219
PNP	-0.010197
MRPL32	-0.010191
MFAP1	-0.010177
NUP35	-0.010151
GOSR1	-0.010149
UBA52	-0.010119
PAPSS2	-0.010111
RPL5	-0.010108
ZFP36	-0.010104
WRB	-0.010101
CUL3	-0.010088
CAPNS1	0.010061
FGB	-0.010058
TIMM17A	-0.010053
LYSMD3	-0.010026
CFAP20	-0.010016
AQP3	-0.009972
ADAM9	-0.009970
TAF7	-0.009968
GNG10	0.009940
SLC7A11	-0.009938
LAMA5	0.009925
FAM46A	-0.009910
CCDC68	-0.009906
POLR2G	0.009898
RNF19A	-0.009873
RPS5	-0.009864
OLA1	0.009856
EMC4	0.009850
MTERF3	-0.009845
DLD	-0.009832
MITF	-0.009827
TBK1	-0.009820
COASY	0.009796
USP3	-0.009767
CRIP1	-0.009747
WDR82	-0.009736
CNN3	-0.009736
BTF3	0.009728
SNORD104	-0.009725
C1QBP	0.009720
RBMX	0.009717
SSR4	-0.009714
TMEM243	-0.009713
ALDH3A2	-0.009711
SRSF5	-0.009700
CLDN12	-0.009680
MAK16	-0.009679
ACP1	0.009653
RARS	-0.009647
TRMT112	0.009634
MALSU1	-0.009624
SLIRP	0.009617