!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	leptin
!ligand_id	PubChem CID: 90470904
!cell_type	liver
!organism	mouse
!end_metadata
APOA4	-0.248013
APOA1	0.245673
ALAS1	0.222698
TTR	-0.181573
GNMT	-0.177902
GPX1	-0.154535
FADS1	0.137081
DBP	0.133222
MAT1A	-0.128295
ATP5G3	-0.127265
CA3	0.126137
OAT	0.126057
FAH	0.124754
HP	0.122633
NUDT7	0.116009
RETSAT	-0.113786
CYP4F12	0.107029
ALDH2	0.105996
CES1	-0.104925
AQP9	0.104804
DMBT1	-0.102842
ALDOB	-0.102137
VTN	0.094700
SCD	0.094072
RNASE4	0.090301
APOF	0.086508
ACLY	-0.085255
FGA	0.084946
EPHX1	-0.084323
WBP1L	-0.080862
ERRFI1	0.080482
ALDH3A2	-0.080037
CHCHD10	0.079326
IFITM3	0.078077
SERPING1	0.075839
ITIH4	0.074368
ACSL5	0.074072
KHK	-0.073983
KRT8	-0.072993
GLYAT	0.072658
CYP8B1	0.072421
INMT	0.072228
CYP2F1	-0.072155
ANXA2	-0.071169
APOE	0.070302
ELOVL5	0.069887
APLP2	-0.065908
SLC22A1	0.065341
DCN	-0.064671
THRSP	-0.064405
ANG	0.064006
FDPS	0.062740
RPS27L	-0.062653
G6PC	-0.061652
SERPINF1	0.061241
GLDC	-0.060633
CYP2E1	-0.059037
CYP7A1	0.058520
UPP2	0.057175
MGST1	0.056026
HPX	0.056021
CD81	-0.055849
RBP4	0.055296
TUBA1B	-0.055261
GSTA5	-0.053183
G0S2	0.052895
AZGP1	-0.050417
RPL9	-0.050208
ACADM	-0.050139
PON1	0.049516
C8G	0.049440
CTSB	0.048580
GAMT	0.048365
PIM3	0.048280
FTH1	-0.047931
ANXA5	-0.047482
HIGD2A	-0.047382
HAAO	0.047238
GAPDH	-0.047055
PTPLAD1	0.046903
HPD	0.046525
CIDEA	-0.045281
HSD3B7	0.045091
CSTB	-0.044659
INSIG2	-0.044574
ANGPTL4	0.044405
LDHA	-0.043926
RPS14	-0.043723
HSD17B10	-0.043209
SLC40A1	0.043048
HAO1	0.042677
REEP6	-0.042017
WBP2	-0.041899
ISCU	-0.041603
IFITM2	0.041404
REG1A	-0.041369
NDUFA1	-0.041238
RGS16	0.041079
TGM2	-0.040943
CLEC4G	0.040942
UBC	-0.040935
APOA2	-0.040646
CYP1A2	0.040517
ITIH1	0.040093
GPT2	-0.040073
CYP27A1	0.039702
CPS1	0.039624
UGT2B17	0.039544
NDUFA13	-0.039343
HIST1H2BG	0.038980
RARRES2	-0.038520
CFI	0.038129
RPS12	-0.037928
DBI	0.037818
NIPSNAP1	-0.037759
ARG1	-0.037637
EBP	0.037552
SLC27A2	0.037324
CTGF	-0.036920
NDUFS6	-0.036863
FGG	0.036723
UQCR10	-0.036387
FMO3	0.036228
ATP1A1	-0.036169
ACSS2	0.036048
ABHD14B	0.035578
IDH1	0.035410
APOM	0.035292
CES3	0.035277
UGT2B7	0.035264
HTATIP2	-0.034976
HERPUD1	-0.034762
HIST1H2BL	0.034699
QDPR	0.034366
SLC38A3	0.034216
TMBIM4	-0.034055
CDO1	0.033804
AMBP	0.033745
C14orf2	-0.033463
C3	0.033285
GSTM5	-0.033157
DAK	-0.032705
GPT	-0.032459
ZFP36L1	-0.032148
PSAP	-0.032135
ABCD3	0.032058
WFDC2	-0.031821
TF	-0.031760
ADH4	0.031552
SOD1	0.031424
ACACA	-0.031258
CBR1	-0.031124
PDIA3	0.031094
CYP3A5	-0.030999
RPL10	0.030973
PPM1K	0.030871
NDUFA10	-0.030568
XBP1	0.030448
ABCB4	-0.030446
GJB2	0.030372
NDFIP1	0.030305
ACOX2	-0.030274
ADK	-0.030088
RPS20	-0.029957
HSD17B4	-0.029943
ALDH4A1	0.029886
RPL27	-0.029744
F2	0.029697
SLC6A6	-0.029535
HBB	-0.029200
GOT2	-0.028832
CST3	-0.028799
IGFALS	0.028442
CTNNA1	-0.028384
NAT8	0.028119
PEMT	0.027894
ACTA2	-0.027568
SERPINA10	0.027360
DUSP1	-0.027343
TMEM205	0.027297
ALDH6A1	0.027265
TST	0.027241
HLA-E	0.026944
RPS17	-0.026793
ORMDL3	-0.026695
C8B	0.026619
ECH1	-0.026353
RPL35	-0.026066
NDUFA7	-0.026027
RPL37A	-0.025975
TUBB4B	-0.025956
TTC36	0.025933
ALAD	0.025870
ELOVL6	-0.025837
BGN	-0.025697
AMFR	-0.025677
CEBPB	0.025646
COX5A	0.025133
PPP1R3C	-0.024922
RPL5	-0.024833
EDF1	0.024682
NAT8B	0.024674
NDUFB8	0.024469
SLC25A47	-0.024270
HMGCL	-0.024264
NRN1	0.024203
RPL38	-0.024097
LGALS1	-0.024067
SLC25A10	-0.024059
F10	0.023921
TM4SF4	-0.023889
HIST2H2AC	0.023842
SLC25A5	0.023293
SFXN1	-0.023173
C5	0.023099
C19orf66	-0.023000
AGT	-0.022967
SOD2	-0.022869
DEGS1	-0.022822
CYP4A11	-0.022750
PSMC2	0.022728
TTPA	-0.022520
CD1D	-0.022502
CRP	0.022482
RPS16	-0.022455
COX8A	0.022389
NDUFA4	-0.022229
MFGE8	-0.022162
HSD11B1	-0.022141
PPAP2B	0.022119
SEPP1	-0.022108
RPS8	-0.021872
HSPD1	0.021699
OAZ1	0.021611
AK3	-0.021603
RPS7	-0.021534
SAA2-SAA4	0.021452
RPS21	-0.021335
CYB5B	0.021254
RPL39	-0.021242
ACAA2	0.021072
GAS6	-0.021026
APOC4	0.020943
ZYX	-0.020844
ETFB	0.020821
HMGCS1	-0.020764
HSPA9	0.020724
NDUFV1	-0.020644
RPL18	-0.020599
ITM2B	-0.020561
CD164	0.020511
FAU	-0.020471
LYPLA2	0.020434
ZFPM1	0.020366
RPS4Y1	-0.020169
ETFA	0.019879
ALDH1L1	-0.019760
DGAT2	0.019741
MMD2	0.019740
COX6B1	-0.019647
GPC1	-0.019575
MSRB1	0.019552
SDS	0.019444
C14orf166	-0.019425
AQP8	0.019364
ANAPC16	-0.019283
PDZK1	0.019209
EIF5	-0.019195
GLG1	-0.019170
PCYOX1	-0.019129
AES	-0.019042
PRELP	-0.018958
LRRC28	-0.018953
MBL2	0.018891
RAB11B	-0.018864
ITIH2	0.018724
ACOT13	-0.018673
IGF1	0.018673
STT3B	-0.018648
AHSG	0.018617
HIST1H1C	-0.018436
RPS2	0.018404
TMEM38B	-0.018399
MVB12A	0.018358
CYP2B6	-0.018278
HINT2	0.018041
RPL36AL	-0.018031
EPHX2	0.017961
METTL7B	0.017939
ACTG2	-0.017914
PAOX	0.017899
ABHD17A	-0.017817
PRELID1	-0.017779
NNMT	0.017563
GSTP1	0.017540
DDRGK1	-0.017421
GSTA3	0.017415
BHMT	-0.017410
PPM1B	0.017312
C9	0.017311
HGFAC	-0.017147
UQCRC2	0.017131
PRDX4	0.017090
ABCC3	-0.017078
B2M	0.017065
SGK1	-0.017063
LCN2	-0.017061
HIST1H2BI	0.017030
NDUFA3	-0.016935
LONP2	0.016787
SLC25A39	-0.016728
PTTG1IP	0.016725
MCM10	0.016710
SLMO2	-0.016682
GAK	-0.016621
TBCA	-0.016573
TMEM109	-0.016571
LAMP1	-0.016530
UQCR11	0.016491
GLO1	0.016481
EI24	-0.016433
VSIG4	0.016421
COQ10B	0.016376
APMAP	-0.016361
PQLC1	-0.016324
FMO5	-0.016321
CHPT1	-0.016310
FADS2	0.016279
APOH	0.016262
APEH	0.016226
ENTPD4	-0.016215
SERINC1	-0.016181
CIDEC	-0.016079
PRDX5	-0.016038
GLTPD2	0.016035
ZFYVE21	-0.015990
RPL37	-0.015976
GSTZ1	0.015969
RPL3	0.015934
PSMB4	0.015749
C8A	0.015720
LGALS3	-0.015691
MMD	0.015690
ME1	0.015644
CYP17A1	-0.015584
GHR	0.015525
CYP4V2	0.015423
GLRX	-0.015417
SHROOM1	-0.015379
HAL	-0.015322
EEF1G	-0.015241
MAN2B1	-0.015219
SEC14L2	0.015185
DIO1	0.015171
SLC25A3	0.015017
UROD	0.015012
SBK1	-0.014998
STBD1	0.014968
GGNBP2	-0.014961
SERPINA6	0.014943
ASL	-0.014929
RNPEPL1	-0.014883
MRPS24	0.014883
CYP4F3	0.014878
FOXA3	0.014820
ADIPOR2	0.014809
ATP1B1	-0.014682
RPS6KA1	-0.014537
PTER	0.014537
CCDC107	-0.014525
TALDO1	-0.014513
AFM	0.014507
NREP	0.014485
HSD17B7	0.014481
SPCS1	-0.014453
PARVA	-0.014449
ASPDH	0.014338
AK2	0.014334
RPL12	-0.014320
PGM1	0.014284
FAM134B	-0.014278
PNPLA7	0.014243
DUS1L	-0.014236
NUDT4	-0.014141
HABP2	0.014136
MGST3	-0.014122
PRNP	-0.014113
DDT	0.014099
ABCG8	0.014058
RNF10	-0.014049
PSMA5	0.013969
PLIN2	0.013944
MLYCD	0.013937
TMEM147	0.013910
RNF44	-0.013893
TMEM50A	0.013882
PGP	-0.013872
HRSP12	-0.013856
ATPIF1	-0.013856
CCBL1	0.013848
KNG1	0.013828
QPRT	0.013726
RPL24	-0.013681
PRDX1	0.013663
GABARAP	-0.013583
IMP3	0.013527
GCGR	0.013523
ABCG5	0.013517
TIMM8B	-0.013501
ATP5C1	-0.013460
BAG1	-0.013421
MRPL38	0.013411
NDUFS3	-0.013409
TSPAN31	0.013393
HIST1H2BN	0.013362
PIGR	0.013316
GLRX5	-0.013292
HSP90B1	0.013276
RPL28	-0.013269
RPS6	-0.013263
ATOX1	0.013228
F12	-0.013203
TBCEL	0.013176
PSMA2	0.013175
SORD	0.013171
SUCLG1	0.013085
ADH1C	-0.013060
MAP2K3	-0.013051
SLC5A6	0.013028
BHLHE40	-0.012975
CFD	-0.012899
AKR1A1	0.012874
F13B	0.012801
LRP10	-0.012787
LY6D	-0.012787
PDHA1	-0.012767
BRI3	0.012690
GJA1	-0.012628
TCEAL8	-0.012614
COX14	-0.012556
HPGD	0.012547
NME2	-0.012542
FAM173A	-0.012526
ATP6V1E1	-0.012512
HSPA8	0.012492
ACADVL	0.012445
LITAF	-0.012441
HEBP1	0.012436
SERPINA12	-0.012389
RAB14	0.012372
CFB	0.012368
FAM214A	0.012350
LLGL2	-0.012155
TGFBR2	-0.012144
SERPINA3	-0.012135
DYNLT3	0.012110
AHCY	-0.012097
SLC25A15	0.012049
ACADSB	0.012001
RPL35A	0.011960
GCH1	0.011928
RCAN1	-0.011912
SEMA4A	0.011851
FAM102A	0.011770
NDUFA2	-0.011757
CHP1	0.011676
GDE1	-0.011675
ALDH1A1	0.011662
IGFBP4	-0.011536
VPS28	0.011528
NRD1	-0.011506
RPS13	-0.011454
TMEM176B	0.011398
COX19	-0.011387
GM2A	-0.011338
C14orf1	0.011337
LBP	-0.011326
HIST1H2BM	0.011314
PDLIM1	-0.011296
TMEM97	0.011290
CTSH	0.011219
AQP1	-0.011212
IGFBP2	0.011148
PBLD	-0.011130
CDHR5	0.011120
FAM129B	-0.011068
SLC38A4	0.010935
LRG1	-0.010911
SPINK1	-0.010881
AGXT	0.010841
SS18L2	0.010774
PAH	0.010726
SERPINA7	-0.010714
COA5	-0.010710
UQCRB	0.010690
UBE2O	-0.010657
ACO2	-0.010656
TMIE	-0.010594
PEX6	0.010574
KLKB1	0.010573