!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!cell	Muscle
!perturbation	Metformin
!Relevant information	diet: ad libitum AIN-93G SD and supplemented with 0.1% w/w metformin 
!end_metadata
CFD	0.127580
SCD	0.098452
APOA2	0.091933
TTR	0.090600
KLF2	0.085611
TMEM45B	0.085448
EGR1	0.083068
ANKRD1	-0.079608
FOS	0.077277
ADIPOQ	0.074953
APOA1	0.070794
NRARP	0.069909
CES1	0.066926
TF	0.066807
CIDEC	0.065851
CDO1	0.065194
DNAJB1	0.063445
HEY1	0.061707
IER3	0.061514
ERRFI1	0.060810
KCNAB1	0.060354
CSRP3	-0.059968
TOB2	-0.059909
AMBP	0.059702
TPRA1	0.059219
FOSB	0.057526
LEP	0.056243
ARRDC2	-0.054502
CYP2E1	0.053720
SOCS3	0.053663
KIAA0513	-0.052833
G0S2	0.052173
MUSTN1	-0.052072
AOC3	0.051307
CACNG1	0.050873
CXCL2	0.049495
COL1A1	-0.049388
BCL6B	0.048684
SRXN1	-0.047999
RGCC	-0.047802
PDK4	-0.047725
HBEGF	-0.047029
CCND2	-0.046731
XIRP1	-0.046709
AMY2A	0.045650
CACNA2D1	-0.045603
BACH1	-0.044760
OGN	-0.044721
KLF4	0.044644
AQP4	-0.044317
EMP1	-0.044204
CHAC1	0.043740
F13A1	-0.043500
NDRG2	0.042794
SERPINA1	0.042609
DDIT4	-0.042483
HP	0.042001
CA3	0.041662
PRKG1	-0.041069
SLC1A3	0.040910
HSPB7	-0.040882
HLA-DQA1	0.040875
MAT1A	0.040745
PAPOLA	-0.040454
ID1	0.040188
TNC	-0.040174
EGLN3	-0.040159
AK1	0.040036
ABRA	-0.039888
CCDC3	-0.039625
RGS5	-0.039454
RCAN1	-0.039399
MCL1	0.039322
JUNB	0.039286
EGR2	0.039196
SMAP1	-0.039182
AKR1B1	0.039055
CYB5R1	0.039054
BHLHE40	0.039008
SNCG	0.038970
AHSG	0.038928
DDAH1	0.038926
IGFBP5	0.038828
IRS2	-0.038031
SMOC1	0.037791
NNMT	0.037574
ALDH1A1	0.037314
DBP	-0.037253
FGA	0.037233
SKAP2	0.037087
NCEH1	-0.036998
LUM	-0.036660
CYP2F1	0.036645
TMEM9	0.036631
LMCD1	-0.036520
GAMT	0.036348
RCSD1	0.036264
BCL6	-0.036262
KCNC4	0.036166
PLIN5	-0.035944
PIM3	-0.035897
TUBB6	-0.035895
JADE1	-0.035697
LGALS1	0.035631
ATP2A2	-0.035611
PCOLCE	-0.035449
FAM131A	0.035125
C10orf10	-0.035104
NFATC3	-0.034911
GOLGA4	0.034878
NHLRC2	-0.034805
EGFL7	0.034588
MYL4	0.034436
SPAG7	0.034365
MAOB	0.034142
EXOC7	0.034135
DCAF11	0.034117
AXL	-0.034094
OLFML3	-0.033973
PDLIM1	-0.033964
CHST1	0.033945
SLC35B1	0.033901
EEPD1	0.033600
TSPO	0.033512
RGS4	-0.033483
HIST1H2BG	-0.033417
VDAC2	0.033349
ACTC1	0.033256
SMYD2	0.033254
PPARGC1A	-0.032962
COL6A1	-0.032955
FBLN1	-0.032941
MRPS18C	0.032752
ITM2A	-0.032645
APPBP2	-0.032594
NFIB	-0.032546
SERPINF1	-0.032546
CYR61	0.032517
TRA2A	0.032451
FAM92A1	-0.032308
ATP1A2	0.032227
EDN1	-0.032225
CIART	-0.032182
TTC1	0.032039
MEF2C	-0.032027
RARRES2	0.031880
C1QC	-0.031757
IRF2	-0.031701
SEC11C	0.031472
CD1D	0.031392
SNAP23	-0.031330
APOE	0.031258
ATXN1	-0.031250
MMD	0.031120
YWHAG	0.030663
LURAP1L	-0.030648
HSD17B10	0.030580
MRPL27	0.030542
CAMK2B	0.030520
PTCD3	0.030233
DUSP8	-0.030205
PLEKHB1	0.030197
ATF5	-0.030154
PER2	-0.030136
NPR3	0.030014
GNL3L	0.030006
TKT	0.029940
MYOM1	0.029915
SYT9	0.029910
RHOJ	-0.029884
HNRNPL	0.029849
DNAJC7	0.029838
NTRK2	0.029490
EDNRB	-0.029476
TNFRSF12A	-0.029472
HDC	0.029447
CYTH3	-0.029425
PRRX1	-0.029389
SLC8A1	-0.029299
KLF13	-0.029292
PHTF2	0.029282
GPX3	0.029258
AKTIP	0.029254
CCRN4L	-0.028990
HES1	0.028886
PDPK1	-0.028841
NDUFAF4	-0.028839
BOP1	0.028734
FOXO1	-0.028680
CCDC12	0.028661
FGG	0.028632
COL6A2	-0.028501
MAFG	-0.028488
POPDC3	-0.028395
KLF3	-0.028334
LYVE1	-0.028304
C5orf28	-0.028203
BAG3	-0.028132
PRKAA2	-0.028070
AARSD1	0.027920
HSPB3	0.027910
ME1	0.027865
BGN	-0.027785
GPD1	0.027732
IGSF3	-0.027723
SDHD	0.027706
LOXL1	-0.027673
MEDAG	-0.027564
PGM1	0.027533
RAMP2	-0.027523
APOC4	0.027502
SERTAD1	0.027485
SLC37A4	0.027485
SNX24	-0.027476
PDGFRA	-0.027466
HIST1H1C	-0.027429
RSAD2	-0.027377
TOR1AIP1	-0.027361
SCARA3	-0.027317
ANXA2	-0.027197
ATP6V1G1	0.027149
MFAP4	-0.027114
COL5A1	-0.027110
TMEM109	0.027020
RDM1	0.026747
TMEM100	0.026742
PLXNA2	-0.026665
TUBA8	0.026632
SETD3	0.026579
DNASE1L1	0.026553
TMEM261	-0.026539
ADAM15	-0.026436
VAMP5	0.026336
COL15A1	-0.026257
GDF10	-0.026242
PES1	-0.026231
MIB1	0.026217
GSTZ1	0.026135
ASAP1	-0.026099
CTGF	-0.026051
BCAT2	-0.026035
CCT8	0.026027
PSMC5	0.026023
CCDC91	0.025964
HIST1H2BL	-0.025941
PPTC7	-0.025792
ESRRB	-0.025749
ALDOB	0.025729
TSN	0.025698
IDE	-0.025664
STT3A	-0.025580
FAM171B	-0.025510
NDUFB9	0.025460
WIPF1	-0.025459
OAZ2	0.025449
CIRBP	0.025427
MMP2	-0.025376
KCNE4	0.025356
MYH11	-0.025311
GSTA3	0.025309
SLC9A3R2	-0.025269
PDHB	0.025223
GADD45B	-0.025195
BCAP31	0.025169
MRPL34	-0.025135
ATP5J	-0.025100
ATP6V0A2	-0.025036
ATP6V1A	-0.024988
PUM2	-0.024986
REEP1	0.024950
S100A10	-0.024947
HLA-DRB5	0.024939
UNG	-0.024908
NAPB	0.024896
CTNNBL1	0.024886
TIMP1	-0.024883
PANK3	-0.024850
HSPB1	-0.024794
DUS4L	-0.024732
ITGB4	-0.024728
AGAP1	-0.024717
PCGF5	-0.024687
EIF4EBP2	-0.024639
SMTNL1	-0.024614
FAM213A	0.024583
CD9	-0.024559
RAMP1	-0.024505
VAV3	-0.024497
AMY2B	0.024443
COA7	-0.024412
FBXO32	0.024390
TECR	0.024370
FAM195A	-0.024368
ART3	0.024354
PLVAP	-0.024339
ANGPTL1	-0.024333
DUSP1	0.024318
PLAU	0.024287
TUBB	-0.024264
MAP3K3	-0.024260
HIST1H3I	-0.024221
ANKRD49	-0.024203
ARRDC4	0.024197
S100A8	0.024156
FEZ2	0.024061
SLC25A33	-0.024032
ACTA2	-0.024030
CSRP1	-0.023968
DRAM1	0.023905
PANX1	0.023904
CCDC107	0.023896
EIF3H	0.023779
PSMD8	0.023754
CTSB	0.023664
UBN2	0.023556
SLC25A34	-0.023533
NFIL3	-0.023490
KIAA1919	-0.023484
USP2	-0.023462
COL7A1	0.023419
KLF7	-0.023415
SNRNP35	0.023378
GPR146	-0.023356
DUSP7	-0.023284
TMED2	0.023283
MRGPRF	-0.023274
COX19	-0.023259
HYPK	0.023237
ITGB5	0.023205
MID1IP1	-0.023190
YIPF7	-0.023189
SCAMP3	0.023180
GNG5	0.023165
AZGP1	0.023102
ATP5H	0.023092
SPPL2C	0.023077
TDRP	0.023072
EBPL	0.023049
NEDD9	0.023036
RBM3	0.023022
MYH1	0.023017
ACAT1	0.023008
IL1B	0.022963
VGLL2	-0.022931
PTPN21	-0.022905
HSPG2	-0.022833
GBP2	-0.022821
CSRP2	-0.022805
LMAN2	0.022801
MYF6	-0.022716
SIRT3	-0.022657
SRP14	0.022648
LRRC30	0.022641
GIMAP6	0.022591
SUCNR1	0.022584
AACS	0.022545
LRRFIP1	0.022530
PRPS1	0.022505
SAMD4A	-0.022502
OCIAD2	0.022488
TUT1	-0.022472
GART	0.022467
LGMN	-0.022451
S100A9	0.022427
ARL8B	0.022422
E2F2	0.022422
DDX1	0.022421
SNX3	0.022390
THRSP	0.022380
C11orf73	-0.022366
MAP3K6	-0.022319
DGKZ	0.022308
PMP22	-0.022266
SEPT9	0.022231
HIST1H3A	-0.022209
KIF13A	0.022202
THAP3	0.022179
ALDH18A1	-0.022168
MDH2	0.022164
FAM76A	-0.022152
RRP15	-0.022143
DHRS1	0.022118
GOT1	0.022088
MPP5	-0.022071
IMPACT	-0.022046
FLT1	-0.022031
IFITM2	-0.022018
SMIM15	-0.022007
PKM	0.022006
RPL35A	0.021991
FAM78A	0.021986
CYB561	-0.021968
TGM2	-0.021942
GRASP	0.021907
SERTAD3	0.021895
LLGL1	0.021854
PNO1	-0.021853
SMAD4	-0.021844
WBP1L	-0.021825
SRSF7	-0.021820
IGBP1	0.021777
FAH	0.021753
FAM222B	-0.021751
METAP2	0.021747
COL4A2	-0.021726
COL1A2	-0.021725
UBE2O	-0.021712
GPT	0.021670
REEP3	-0.021653
PCYT1A	-0.021622
SMG7	0.021615
ZDHHC21	-0.021506
GNA13	-0.021475
TMEM205	0.021472
DYNLL2	0.021443
HIST1H2BN	-0.021407
MARCH2	0.021405
SNX16	-0.021396
ACSL1	-0.021378
GSK3B	-0.021372
RPL5	0.021349
STXBP4	0.021335
PRRC2A	0.021321
ZNF23	-0.021314
COQ7	0.021298
PTGIS	-0.021211
HHATL	0.021197
USP1	-0.021187
APRT	-0.021182
SPHK1	-0.021156
PFDN4	-0.021144
FSTL1	-0.021120
ITGB1BP2	0.021105
HAGHL	0.021103
LIMS2	-0.021077
APOF	0.021069
VPS37C	0.021068
MTDH	-0.021029
NDUFB7	0.020999
IKZF5	-0.020998
PDGFB	0.020973
WDR6	0.020967
PRDX5	0.020960
CRP	0.020941
TMEM38A	0.020912
MYOZ2	-0.020903
TRAFD1	0.020891
MRC1	-0.020887
ADCY4	-0.020810
C2	0.020805
PCCB	0.020805
LRFN3	-0.020790
PCBP1	-0.020786
LRP11	0.020779
NUP210	-0.020772
VGLL4	0.020750
ASF1A	-0.020727
GPR107	0.020726
SQRDL	0.020714
EMILIN2	-0.020697
PANK4	-0.020694
ARHGAP24	-0.020684
COMP	-0.020653
VPS33A	0.020644
SLC25A5	-0.020611
THY1	-0.020598
HPX	0.020592
MVB12A	0.020583
REEP5	0.020543
TFB2M	-0.020524
COL3A1	-0.020494
NET1	0.020450
DCUN1D1	-0.020420
EMG1	0.020413
ZNF281	-0.020400
UFC1	0.020372
CLEC10A	0.020371
PEBP1	0.020344
FBXL3	0.020340
AMD1	-0.020339
TANK	-0.020307
VAMP8	0.020289
POLR2G	0.020256
FAM105B	-0.020246
TAB2	-0.020240
SMOX	-0.020239
THBD	-0.020224
PDPN	-0.020206
PHKG1	0.020204
ARHGAP29	0.020186
PSMD4	0.020146
TWF2	-0.020137
CCNDBP1	0.020136
SMAD3	0.020133
PTEN	-0.020126
KDM6A	-0.020115
PJA2	-0.020089
TXNIP	0.020078
NQO1	0.020055
UQCRB	0.020055