!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Cigarette Smoke
!smiles	C1=CC(=CC=C1N)S(=O)(=O)OC2=C(C=C(C=C2[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-]
!pubchem_cid	57288536
!cell_type	Alveolar Macrophages
!organism	human
!end_metadata
CCL18	-0.171994
CES1	-0.153447
CXCL10	-0.127595
HLA-DMB	-0.124085
FABP5	0.123063
LYZ	0.116691
TNFAIP6	-0.112679
ALDH2	-0.111394
FABP4	0.108689
GBP1	-0.106709
PLIN2	0.104481
ACP5	0.103850
MT1F	-0.099147
SERPING1	-0.099138
GCH1	-0.093186
HLA-DPB1	0.092841
PSME2	-0.092116
CA2	0.090211
TGFBI	-0.085996
C1QA	-0.083960
WARS	-0.083034
TNFSF13B	-0.082914
LAIR2	-0.081531
NCF1C	-0.080616
MCEMP1	0.078178
ITGAE	0.076830
MT2A	-0.075020
COX6C	-0.074358
MT1E	-0.074106
PSMB9	-0.072605
RAB31	-0.071047
C1QB	-0.071044
RPS4Y1	0.070443
ABCG2	0.070154
PPT1	-0.069760
AKR1C2	0.068993
LAP3	-0.068769
APOC1	0.067984
PCOLCE2	-0.067880
CYP27A1	0.067285
MT1HL1	-0.066644
CXCL9	-0.066315
IL1B	-0.066032
MT1X	-0.066025
CCL2	0.065231
CD81	-0.065159
LGALS3BP	-0.065005
SOD2	-0.064980
FUCA1	0.063892
FCGR1B	-0.063814
CTSL	0.063814
CCL4	-0.063270
MSR1	0.063174
CTSH	-0.062789
NDUFA12	-0.061084
AKR1C3	0.060646
COX2	0.060131
HCK	-0.059993
CD52	0.059890
CSTA	-0.057786
HSD11B1	-0.057725
HSPA1A	0.057146
MT1H	-0.056817
TAGLN2	-0.056746
STAT1	-0.056461
SLAMF8	-0.054215
S100A8	-0.054055
HLA-DQA1	-0.053669
RPL8	0.053503
ARPC3	-0.053420
AKR1C1	0.052657
FN1	-0.052656
IFI27	-0.052465
TAP1	-0.052453
LOC100506098	0.052374
BASP1	0.052289
SGK1	0.052229
CD74	-0.051641
PDLIM1	-0.051452
MT1M	-0.050837
NME7	-0.050769
ANXA1	0.050762
CCL23	-0.050147
MGST1	0.050106
CEBPB	-0.049521
NFKBIA	-0.049437
ATP6V0D1	0.048848
RPS14P3	0.047929
CYP1B1	0.047926
PKM	-0.047671
RAB13	-0.047556
CRIP1	-0.047389
CD164	0.047001
FGR	0.046977
DPYSL2	-0.046937
CTSC	-0.046758
RPL4	0.046172
PPP1R18	-0.046054
ACP2	-0.045686
ATP6AP1	-0.045503
LCP1	-0.045195
BCL2A1	0.045183
ALAS1	-0.044180
NDUFA1	-0.044118
GPR34	0.044060
MS4A4A	0.043403
INHBA	-0.043291
SRP14	-0.043145
IL10RA	-0.042866
MIF	-0.042706
SDCBP	0.042549
CAP1	-0.042500
EPHX1	-0.042063
AQP9	0.041926
ACTB	-0.041915
HIST1H2BK	0.041103
MYD88	-0.041029
HLA-DPA1	-0.040996
CST3	-0.040521
PNRC1	-0.040457
TMA7	0.040442
ARL6IP1	0.040260
BLVRB	0.040134
C1QC	-0.040036
CLIC1	0.039990
NCOA4	-0.039807
TALDO1	0.039804
GRN	-0.039386
OPN3	0.039376
IFIT3	-0.039338
PPBP	-0.039238
TMBIM1	0.039062
HLA-DRA	0.038748
GPR137B	0.038600
LAPTM4A	-0.038390
ALOX5AP	0.038110
GYPC	-0.038106
YWHAE	-0.038060
NDUFA4	-0.037915
S100A10	-0.037882
MRC1	-0.037767
CD14	-0.037735
RPL23	0.037680
MNDA	-0.037644
GLIPR2	-0.037599
CYB5R3	-0.037589
ALDOA	0.037479
JTB	0.037405
NPTN	-0.037264
DFNA5	0.037161
CSF1R	-0.036965
PSTPIP2	-0.036785
VSIG4	0.036679
EIF4A1	0.036604
HMGN3	-0.036569
LGALS3	0.036420
RPL9	0.036363
PILRA	-0.036353
MAFF	0.036331
RPL12	0.036303
GBP5	-0.036228
PSMA1	0.036217
LTA4H	0.035767
C1orf162	0.035698
PSMA7	0.035597
YWHAZ	0.035342
IL2RG	-0.035252
NOP10	0.035230
ANXA2P2	0.035039
LYSMD2	-0.034909
RPL13	0.034900
CORO1C	0.034827
ZYX	-0.034226
EEF1G	0.034221
ADORA2B	0.034176
LAPTM5	0.034022
DYNLT1	-0.033872
ATOX1	-0.033631
LY96	-0.033566
NAGK	0.033439
CAPN2	0.033328
DHRS9	0.033288
CLEC4E	-0.033109
APOE	0.033074
TMSB10	0.033035
SLC26A11	0.032951
RPL6	0.032948
GCHFR	0.032929
GNG5	0.032883
ETHE1	-0.032807
PLEKHB2	0.032777
USMG5	-0.032733
RNASEK	0.032613
RPS2	0.032590
RAP1B	-0.032527
ATF4	0.032514
TRIM22	-0.032466
IFNGR2	-0.032373
PSMB4	0.032197
HLA-E	-0.032176
IRF1	-0.032169
HSP90AB1	0.032169
RPL3	0.032127
IFITM3	-0.032117
OAT	-0.032039
SLC38A6	0.032022
C20orf24	0.032012
ATP6V0D2	0.031977
IGSF6	0.031778
VAT1	-0.031767
MDH1	-0.031621
RPLP0	0.031614
C1S	-0.031576
SLAMF7	-0.031438
SPP1	0.031431
PLSCR1	-0.031312
ARL6IP5	-0.031202
HLA-F	-0.031110
GPX3	-0.031062
TUBA1C	0.030866
CXCL16	-0.030864
GLA	0.030786
TXNRD1	0.030774
HADHA	0.030752
CNBP	0.030683
NEAT1	0.030667
RPS10	0.030502
COTL1	-0.030490
IRF2BPL	-0.030428
CSF2RB	-0.030376
SDC2	0.030269
NMI	-0.030219
S100A13	0.029709
COX8A	-0.029563
S100A9	0.029533
HEXB	0.029431
RPS19	0.029410
MIR21	0.029396
NUPR1	-0.029372
EEF1A1	0.029269
FBXO6	-0.029246
EPSTI1	-0.029198
SLC31A2	-0.028759
TDP2	0.028728
CXCL5	-0.028696
CD86	0.028340
C15orf48	-0.028335
TMEM14C	0.028306
NINJ1	-0.028293
PSMB8	-0.028230
A2M	0.028135
IARS	0.028070
VIM	-0.028025
PLA2G7	0.027470
GBP2	-0.027244
IFI30	-0.027182
RHOG	-0.027075
NMB	0.026994
PTMA	-0.026903
LHFPL2	-0.026872
COX6B1	-0.026869
LAMP1	-0.026825
CXCL8	0.026810
SNRPG	-0.026714
TUBA1A	0.026500
PSMG2	-0.026483
TUBB2A	0.026459
AIF1	-0.026401
UBE2L6	-0.026317
DAD1	0.026242
APLP2	0.026163
PNRC2	0.026145
DYNLL1	-0.026125
SSR2	0.025996
SLC39A8	-0.025991
GLUL	0.025890
VAMP8	0.025795
KYNU	-0.025786
DHRS3	0.025739
CXCL1	-0.025712
YBX1	0.025689
IFITM2	-0.025677
TFRC	0.025596
C14orf119	0.025551
FLNA	-0.025540
ANXA5	0.025436
HLA-A	0.025435
RTN4	-0.025434
SOAT1	0.025366
PPA1	-0.025353
MAPK6	0.025327
ACSL1	0.025205
YWHAQ	0.025162
TRMT112	0.025087
CFL1	-0.025063
MALAT1	0.025062
SEC11A	0.025056
RPL10A	0.025049
HLA-DMA	-0.025046
TSPO	-0.024945
ATP1B1	-0.024931
HSPE1	-0.024919
NCKAP1L	-0.024889
CD47	-0.024889
CCDC115	-0.024841
RPS5	0.024810
CHI3L1	-0.024780
UBE2E2	-0.024737
SLA	0.024687
IAH1	-0.024665
FDX1	0.024565
BRI3	-0.024554
GSTO1	0.024472
STIP1	0.024423
FAM129A	-0.024354
BCAP31	0.024267
RTN1	-0.024196
DNASE2B	0.024082
AIM2	-0.024044
EIF5	0.023980
CPED1	-0.023941
ADAR	-0.023916
SLC2A6	-0.023713
SARAF	0.023644
CD83	0.023618
MARCKS	-0.023610
KAL1	-0.023599
KIAA0930	0.023547
FXYD5	-0.023447
C1orf54	-0.023419
PLAUR	-0.023364
RPS12	0.023223
HLA-DQB1	-0.023079
HMOX1	0.023059
RPS13	-0.022954
ARL8B	0.022936
TMEM138	0.022546
SERPINA1	-0.022544
ALDH1A1	-0.022528
GPX1	0.022430
PPP1CC	0.022401
SNX10	-0.022388
ATP6V0B	0.022249
AGPAT9	0.022227
PARP12	-0.022187
DNAJA1	-0.022165
GIMAP4	-0.022108
SLC15A3	-0.022099
MS4A7	-0.022017
PRPS2	-0.021974
SELK	-0.021949
FABP3	0.021898
GPX4	-0.021870
SMCO4	-0.021773
HSD17B11	0.021729
TREM2	0.021696
DCSTAMP	0.021659
TLR2	-0.021584
SLC25A5	-0.021579
SNRPD2	-0.021558
ACTG1	0.021541
RPL18	0.021410
ICAM1	-0.021367
NCEH1	0.021363
PEBP1	-0.021363
CD44	-0.021332
MOSPD1	0.021174
TM6SF1	0.021137
NSA2	0.021118
PRDX1	0.021053
SHFM1	0.021052
ITGAL	-0.021042
C17orf49	-0.021025
DOCK11	0.020978
SUMO2	-0.020872
RHOA	0.020839
DDX5	0.020808
ATP6V0C	0.020788
OAS1	0.020703
DNASE2	-0.020701
EVI2B	0.020695
POLR2G	0.020609
CLIP4	0.020604
G0S2	-0.020551
RNF13	0.020505
HCLS1	-0.020504
PRKCD	-0.020493
PHACTR1	0.020463
SNHG8	0.020455
NDUFAB1	-0.020346
CAPG	0.020313
RILPL2	-0.020268
PDCD10	0.020257
MARCO	0.020257
CPVL	-0.020250
IL10RB	0.020243
P4HB	-0.020240
RPS11	0.020232
SRXN1	-0.020189
FAM134B	0.020158
EIF3K	-0.020109
C3	-0.020073
NAA50	0.020069
CMTM6	-0.020057
RPS6	0.020041
NFKB1	-0.019991
SLC27A3	-0.019946
ASAH1	0.019909
MME	0.019871
TMEM140	0.019807
ADK	0.019766
RASSF3	-0.019730
UBA52	0.019634
ZNFX1	-0.019575
GNG10	-0.019547
XIST	-0.019544
SNHG5	-0.019528
RFX5	-0.019525
CXCL3	-0.019480
FAM26F	-0.019446
SERINC1	0.019442
CYFIP1	0.019437
SEPW1	0.019417
CHCHD10	-0.019333
PSMA4	-0.019317
KIAA1033	0.019306
PSMB6	-0.019289
BLVRA	0.019240
CRIM1	-0.019239
VWA8	-0.019168
RPL11	0.019165
PLEK	-0.019131
B4GALT1	-0.019065
MMP12	0.019023
DEFB1	-0.018967
MKNK2	-0.018953
PCK2	-0.018856
MXI1	0.018835
MYOF	-0.018787
CS	-0.018695
C1orf122	-0.018686
TIMP2	-0.018668
ME2	0.018639
PSMA6	-0.018598
NDUFA13	-0.018577
CD53	-0.018563
SRP9	0.018542
EIF3L	0.018535
HLA-DRB6	-0.018484
SH3BGRL3	-0.018480
TMEM251	0.018428
MCL1	-0.018426
SCP2	0.018367
CHCHD2	-0.018358
NRIP1	0.018327
MINK1	-0.018321
RPL36A	-0.018318
DENND2D	0.018287
C14orf2	-0.018281
PPIB	0.018253
GPNMB	0.018214
CDC42SE2	-0.018183
SIRPA	-0.018183
SEMA3C	0.018102
HSP90AA1	0.018077
IGFBP2	-0.018063
HPGD	0.018038
DDX60	-0.017970
HIF1A	0.017957
ATP6V1E1	0.017955
UBC	0.017917
RPL38	-0.017885
EPB41L3	-0.017843
MMP10	-0.017819
SLIRP	-0.017816
RPS3	0.017761
GABARAP	-0.017650
AMICA1	0.017643
PSMD2	0.017634
HLA-B	-0.017587
AKR1B1	-0.017564
RPL28	0.017540
CREBL2	-0.017458
TXNDC12	-0.017431
SRSF9	-0.017419
LGMN	-0.017390
GGCT	0.017343
CARD16	-0.017304
LY75	-0.017302
PDCD6IP	0.017282
TIMP1	-0.017280
TRIM28	-0.017257
CLTA	-0.017255
EIF3G	0.017247
KIAA0247	-0.017231
SERF2	0.017160
MMP19	0.017149
CCR1	-0.017099
TNFRSF21	0.017098
CCL20	-0.017070