!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Methamphetamine
!smiles	CC(CC1=CC=CC=C1)NC
!drugbank_id	DB01577
!pubchem_cid	10836
!cell_type	striatum, day 18 withdrawal
!organism	mouse
!end_metadata
TTR	0.294753
ND4L	-0.180024
KRT14	-0.178105
LTF	-0.158284
PRKCD	0.141212
C8orf46	-0.110517
MYL4	-0.107820
HBB	-0.104034
SLC13A4	-0.098311
SLC17A7	-0.098206
PMCH	-0.096764
ND5	0.096674
S100A5	-0.094080
GBX2	0.093668
CSHL1	0.088607
NTN5	-0.087972
TBR1	-0.087508
NEUROD2	-0.086979
STMN1	-0.085985
CALB2	0.085420
SLC30A3	-0.083767
SLC17A6	0.083282
SPARCL1	-0.081936
KIAA1462	-0.078005
SLPI	-0.075540
EMP1	-0.072040
TMEM178A	-0.071210
PLIN4	0.070205
CORT	-0.068247
CCK	-0.065591
ALAS2	-0.064204
RGS16	0.062464
PSCA	-0.061574
R3HDM2	-0.061102
CHMP5	-0.059923
MICU3	-0.058697
TNNT1	0.057168
KRT17	-0.056805
BHLHE22	-0.056396
NRN1	-0.056330
COX2	-0.056323
PRL	0.056240
H3F3C	-0.055908
CTGF	-0.054371
MAP2K1	-0.054086
CYFIP2	-0.054075
SPINK8	0.053850
TMEM184C	-0.052439
PTPRB	-0.052186
MLIP	-0.049558
RPRM	-0.049469
NPTX1	-0.049435
STX1A	-0.048489
GLUL	-0.047946
ACER2	-0.047311
NR4A2	-0.047256
NDUFB9	-0.046913
HSPE1	-0.046185
VIP	-0.044851
GPR151	0.044502
GRP	-0.043742
MGP	-0.043588
C15orf61	-0.042577
OLFM1	-0.042020
CNFN	-0.041835
C2orf40	0.041278
KRT23	-0.041138
CALML5	-0.040680
TNNC1	-0.040586
KRTDAP	-0.040016
STK32C	0.040001
C17orf96	-0.039647
GAL	0.039357
LGALS3BP	0.039334
MXI1	-0.039002
DRD1	-0.038570
THBD	-0.037972
OVOL2	-0.037927
CRHBP	-0.037156
OXT	0.037047
SLC6A3	-0.036989
ZNF442	-0.036948
ERBB2IP	-0.036824
IGF2	-0.036583
CGA	0.036309
CBLN1	0.036154
AGT	0.036010
IPCEF1	-0.035942
DDX3X	-0.035919
GHITM	-0.035720
SLC12A5	-0.035667
KCNE2	0.035597
ZIC1	0.035509
BGN	-0.035452
S100A10	-0.035340
HSPB3	-0.035257
NAP1L5	-0.035239
SARNP	-0.035071
VPS26B	-0.034914
C15orf48	-0.034868
ADAM9	-0.034855
PLS3	-0.034460
EGR2	0.034429
LY6G6C	-0.034357
SEPT9	-0.034032
PAIP2	-0.033775
FOXG1	-0.033712
STAC2	-0.033467
ATRNL1	-0.033433
MAF	-0.033412
ND6	-0.033408
RPTN	-0.033125
PIK3R4	-0.032846
ATP1B1	-0.032630
VAPA	-0.032166
ALDH3A1	-0.031676
RGMA	-0.031437
SLC39A10	-0.031212
CPNE7	0.031207
ECEL1	0.031187
ACTA2	-0.031069
LIN7C	-0.031002
HSP90AA1	-0.030821
GNG8	0.030684
GPR17	0.030417
HEBP1	0.030373
NDUFB4	-0.030354
ISLR2	-0.030235
SEC11C	-0.030152
SOX18	-0.030053
ATP2A1	0.029731
GRAMD4	-0.029702
MPPED1	-0.029689
SLC6A13	-0.029655
GATA2	-0.029653
EVL	-0.029634
FRMD7	0.029622
ELTD1	-0.029556
DKKL1	-0.029439
ARHGAP15	-0.029408
RASL11B	-0.029394
PRMT8	-0.028972
FRZB	-0.028935
FEZF2	-0.028877
CHST8	0.028531
OMP	-0.028393
MTMR12	-0.028355
KRT4	-0.027950
TRIM37	-0.027935
FOXC2	-0.027412
GPR88	-0.027185
ATP6V1A	-0.027009
ATP5A1	-0.026971
PTGDS	-0.026887
DCTN1	-0.026847
TCAP	-0.026645
UBE2J1	-0.026565
SPCS2	0.026551
IDO1	0.026284
FLT1	-0.026234
SERPINI1	-0.026051
SPRR1A	-0.025977
TBC1D19	-0.025778
CDHR1	-0.025764
HIGD1A	-0.025693
WNT10A	-0.025565
C1QL2	0.025535
TSPAN3	-0.025480
MYL9	-0.025445
WNT3	0.025409
PLEKHA3	-0.025024
SOWAHB	-0.024898
TPPP3	0.024864
NUDCD2	-0.024860
MAPK11	-0.024826
GJB2	-0.024759
PLAC8	-0.024696
FAM19A4	0.024619
CPSF2	0.024608
ARPC2	-0.024607
SP8	0.024489
CD74	-0.024392
RSAD2	-0.024321
NAMPT	-0.024273
RASL11A	0.024268
JUNB	0.024168
P2RY12	-0.024143
ME1	-0.023756
MAP1LC3B	-0.023735
NTNG1	0.023581
ALCAM	-0.023472
SATB1	-0.023451
C7orf60	-0.023428
PFKFB3	0.023352
FAM131A	-0.023285
KPNB1	-0.023245
CRYBG3	-0.023217
TSHZ3	-0.023112
DDT	-0.023013
STK32B	0.022915
TOMM70A	-0.022873
GSTO1	-0.022734
HERC3	-0.022636
HAP1	0.022545
XDH	-0.022519
PRR7	0.022506
ACTB	0.022473
FAM180A	-0.022421
TAC3	0.022351
TRH	0.022209
GPR153	0.022203
CCDC3	-0.022089
FOS	0.021941
OTX2	0.021903
TSR3	0.021886
RAMP3	0.021850
SLC38A5	0.021811
SDHD	-0.021716
FAM107A	-0.021699
SLC5A7	-0.021672
FOXQ1	-0.021667
IDH3A	-0.021630
OGN	-0.021586
MAPRE3	-0.021510
PTGES3	-0.021431
PTPN1	0.021339
ADAMTS19	0.021328
EGR4	0.021278
CNIH3	-0.021250
KIAA1239	0.021181
ECI2	-0.021141
EMP2	0.021100
EIF4G2	-0.021087
DCT	-0.021082
RSPH1	0.021069
CYP2F1	-0.020986
LCN2	0.020970
CCKBR	-0.020827
CALML4	0.020769
EHD1	0.020691
GCLC	-0.020619
PDE1A	-0.020568
NKIRAS1	-0.020549
ZFP1	0.020542
AMOTL1	0.020524
DEK	-0.020512
NCALD	-0.020490
APCDD1	-0.020476
SERPING1	-0.020395
GPM6B	-0.020379
PARP8	-0.020346
GOPC	-0.020309
EMCN	-0.020289
RGS9	0.020251
PMPCB	-0.020230
OTX1	-0.020130
DZANK1	-0.020113
OTOP2	-0.020029
NDFIP2	-0.020012
TTC9B	-0.020011
HCRT	-0.019999
CYP46A1	0.019953
CETN2	-0.019945
SFR1	-0.019921
FAM216B	0.019774
SLC4A1	-0.019768
LRG1	-0.019761
SLC35D3	0.019749
KLF2	-0.019745
PGRMC1	-0.019721
PDZRN3	-0.019712
RSPO2	-0.019693
STARD8	-0.019641
TTYH2	0.019624
RGS14	0.019605
HLA-DQA1	-0.019581
PCNA	0.019400
DLGAP1	-0.019388
IL12A	-0.019349
SYT13	-0.019287
JAM3	-0.019279
NOTCH1	-0.019236
PWP1	-0.019105
RAPGEF3	0.019035
NTRK1	0.019023
NPC1L1	0.019006
C6orf15	-0.019003
CD93	-0.019001
GDPD5	0.018917
CHPF	-0.018876
ENG	-0.018844
PTPRA	-0.018793
AEBP1	-0.018751
TMEM158	0.018731
RASSF3	-0.018720
CCNG2	-0.018682
SPON1	0.018653
KCNAB3	-0.018647
ARNT2	-0.018624
PRELP	-0.018613
SOSTDC1	0.018597
KCTD12	-0.018558
DKK3	-0.018491
TRRAP	0.018439
ENO1	0.018434
TSPAN33	0.018430
PLEKHA2	-0.018428
NDUFA5	-0.018376
NOSTRIN	-0.018370
SGK1	-0.018367
TRMT10C	-0.018358
SIX3	0.018316
UBE2QL1	-0.018298
VAT1L	0.018281
SNX1	-0.018259
KCNA5	-0.018230
ITIH3	0.018187
HLA-DRB5	-0.018107
ITIH2	-0.018091
B4GALT4	0.018074
MEF2C	-0.018022
DOK3	0.018018
CHRD	0.017967
SLIT1	-0.017931
LYSMD2	-0.017894
CKMT2	0.017830
ISG15	0.017824
GPX3	0.017821
S100A9	-0.017724
ANXA1	-0.017704
RASL10A	-0.017621
IGFBP2	-0.017613
KRT13	-0.017487
AKR1C3	-0.017475
NRIP3	0.017429
COQ2	-0.017418
RET	0.017417
CALR	0.017351
TGFB2	-0.017347
ZNF93	-0.017345
CYP2S1	-0.017246
RASAL2	-0.017225
CTSS	-0.017191
PLEKHJ1	0.017147
VHL	-0.017129
BTBD10	-0.017102
NDUFB5	-0.017060
LOC101929327	0.017039
CAV1	-0.017011
CHIC1	-0.016991
ARG1	-0.016987
CHMP4B	0.016940
SYNDIG1L	0.016927
CCDC6	-0.016909
C1orf192	0.016883
SEL1L3	-0.016874
FLJ22184	-0.016845
SOX17	-0.016798
HUWE1	-0.016797
C11orf95	-0.016760
RXRG	0.016740
IGSF1	0.016728
SEPP1	-0.016724
PCDHB16	-0.016714
MBIP	-0.016694
RARRES2	0.016661
F13A1	-0.016627
SYT17	-0.016625
VBP1	-0.016604
VAPB	0.016587
GLTSCR2	-0.016556
SSTR2	-0.016555
ST8SIA5	-0.016458
ANKRD46	-0.016453
IGSF21	-0.016434
ODF3B	0.016423
SIK2	0.016378
TWISTNB	-0.016342
PSMD14	-0.016339
IRS2	0.016338
PSMD6	-0.016304
LYPD1	0.016303
LGALS3	-0.016245
HMGCS2	0.016239
SLC37A4	0.016216
MIP	0.016214
NPAS4	0.016210
ITGAL	0.016186
DCN	-0.016150
FSTL5	-0.016146
COL24A1	-0.016137
VAT1	0.016098
APOO	0.016083
SLC33A1	-0.016080
PAMR1	-0.016040
GOLGA7B	-0.015981
HAPLN2	0.015976
ST6GALNAC2	-0.015954
SORL1	-0.015890
ELFN2	-0.015883
MYL2	0.015877
TUBA8	-0.015865
VWF	-0.015852
FAM179A	0.015821
SRP72	-0.015814
LRRN2	-0.015767
CYP1B1	-0.015765
KIAA1279	-0.015763
HDAC11	0.015733
SGTB	-0.015727
MCTP1	-0.015691
GSTM1	-0.015689
ISL1	0.015685
TEX40	-0.015648
TCF7L2	0.015613
GFAP	0.015607
NFU1	-0.015599
KCTD3	-0.015543
PADI6	-0.015536
HCFC2	-0.015494
GMFB	-0.015492
TRIM59	-0.015480
LMTK3	0.015465
SLC2A1	-0.015452
ENC1	-0.015441
SLC25A4	-0.015441
BHLHE40	-0.015430
PHF19	0.015430
PLD2	0.015394
SYT9	0.015385
CRTAC1	-0.015338
GPM6A	-0.015277
MAS1	-0.015215
RHBDD3	0.015138
RGS5	-0.015114
ZG16	0.015109
NOL7	-0.015079
COX11	-0.015077
NAP1L3	-0.015072
GMPPB	0.015055
C1QA	0.015053
ADARB1	0.015017
PDYN	0.014996
DND1	0.014994
LZTS1	0.014975
EEPD1	-0.014962
PAM16	0.014938
KDELR1	-0.014923
HPRT1	-0.014891
PSME2	0.014884
PCDHB8	-0.014864
LCT	0.014848
ZCCHC12	0.014827
COX7B	-0.014819
KRT5	-0.014811
PPP1R1B	0.014791
PPEF2	0.014782
PIN4	-0.014716
NSG1	-0.014656
LYPD6B	-0.014649
PTPRJ	0.014644
GATM	-0.014597
IL17RA	-0.014577
JUN	0.014565
ANKRD2	0.014547
FHL2	-0.014547
HIST1H1C	-0.014544
C5orf46	-0.014531
RNF112	-0.014522
FIBCD1	0.014489
HS3ST3A1	-0.014475
HIST1H2AG	0.014454
BTBD2	-0.014421
ASPRV1	-0.014419
VPS4B	-0.014418
NUDT4	-0.014400
ISYNA1	0.014399
PHF20	-0.014384
ABCC4	-0.014378
ID2	-0.014378
ATP13A5	-0.014371
SLC6A12	-0.014360
NCCRP1	-0.014358
DHCR24	-0.014347
ALOXE3	0.014330
CTSV	0.014326
KLK8	0.014302
NRSN1	-0.014301
DENND3	-0.014257
IDE	-0.014245
PLOD1	0.014244
DLK1	0.014228
ATP1B2	-0.014210
NNAT	0.014209
TRAPPC6B	-0.014207
NRSN2	0.014204
ASB10	0.014190
SCRG1	0.014185
NPPA	0.014170
GAMT	0.014169