!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!gene	SIRT1
!cell	Liver
!perturbation	Knockout (Heterozygous)
!disease	Ad Lib diet
!end_metadata
DCT	-0.130505
BDH2	-0.112686
ACOT4	-0.109521
PSMD8	-0.102519
SERPINA12	-0.099779
MGST1	-0.098695
CYP17A1	-0.090961
SLC39A4	-0.087027
HLA-DRA	-0.082726
OBP2B	0.081728
ZNF91	0.079405
PRCP	0.078832
CTSE	-0.076078
OVOS2	-0.075354
FBXL3	-0.074965
CISH	-0.074701
ETNK2	0.073802
TTC27	0.068403
MIPEP	0.064135
NCOA4	-0.063599
PICALM	0.062703
FGF21	0.062633
CCRN4L	0.059447
BCL6	0.057372
ESRRB	-0.055826
YIPF4	-0.052516
SCARA5	-0.051913
SRD5A2	-0.049798
NUDT7	0.049572
FAM213A	-0.048577
EGR1	-0.048447
FOXQ1	-0.046790
NAT8	-0.046684
SNX10	-0.045689
SLPI	-0.045675
NUDT18	0.045616
CHCHD4	0.045546
UPP2	-0.045263
RBBP9	-0.044529
HAPLN4	0.044080
ACER2	-0.043638
CCDC126	-0.043454
SLC25A30	0.042757
CYP46A1	0.042371
USP18	-0.042050
IGFBP5	-0.041099
EIF4EBP3	-0.040383
CRYGN	-0.040353
LPL	0.040313
FKBP5	-0.039873
GDF10	-0.039788
ADAT2	-0.039474
MFSD2A	0.038110
APOA4	0.037908
MYADM	-0.037193
IL6ST	-0.037167
PDRG1	0.037155
PPARGC1B	-0.036204
SLC25A25	0.036067
ABCB4	0.036021
SUGCT	0.035810
SH3BGRL	-0.035612
PLEKHB2	0.035385
TNFRSF11B	-0.035226
SLC4A1	0.034373
HJURP	-0.034226
SLC25A17	-0.034147
BHLHE40	-0.033904
CDH1	0.033215
EPHX1	0.032720
TMC7	-0.032622
LYVE1	-0.032607
FPR2	0.032590
YPEL5	0.032488
MRC1	-0.032139
FAM213B	0.031509
ALDOB	-0.031296
XDH	0.031279
OAT	0.031260
FAM126A	0.030905
MRPS12	-0.030810
CIAPIN1	0.030760
ALDOC	-0.030533
WFDC2	0.030426
MRAP	0.030383
ERMP1	-0.030334
ELOVL3	0.030204
QDPR	-0.030201
SLC13A2	-0.029565
CXCL13	-0.029558
WSB1	-0.029319
ERO1LB	0.029279
ELOVL6	-0.029244
BCO2	0.029173
HIPK2	0.028920
MRPS27	0.028737
VEGFC	-0.028596
DNAJC3	0.028492
NUP160	-0.028342
NIPSNAP3A	-0.028261
SALL2	-0.028061
VCAM1	-0.028036
PBLD	-0.027986
PHLDA1	-0.027940
GPR135	-0.027925
CITED2	0.027755
MYCL	-0.027743
CHRNA4	-0.027732
SBSPON	0.027634
NT5C3A	-0.027632
URAD	-0.027610
PCDH17	0.027484
GTPBP3	-0.027477
ABCG8	0.027406
SLC12A7	0.027293
SPSB4	0.027233
SPCS3	-0.026798
SLC13A4	-0.026784
PRPF39	0.026779
HSD17B6	-0.026679
FAM168B	0.026355
CD207	0.026249
ACLY	-0.026214
DCLK3	-0.026103
TIMM9	0.026050
CYP1A2	0.025991
PSTPIP2	0.025889
IRF7	-0.025889
SLAMF9	0.025889
SNCA	0.025881
ALDH6A1	-0.025849
DHRS4	-0.025805
TBC1D20	0.025797
SLC2A4	-0.025795
SPON2	-0.025688
GBP4	-0.025658
LCN2	0.025609
KLHL21	-0.025579
RERG	-0.025566
SLC22A1	0.025495
DHCR24	0.025405
FH	-0.025388
CSRP3	-0.025183
PPTC7	-0.024902
RPS2	0.024829
CELA1	0.024472
SAMD9L	-0.024465
CENPM	0.024462
RBMX	-0.024425
UAP1L1	0.024379
SLC26A4	-0.024377
EHHADH	-0.024241
CDKN1A	-0.024196
ASNS	0.024176
LGALS4	-0.024102
IQGAP2	-0.023982
ETNPPL	-0.023860
MMD2	0.023845
SNX6	-0.023767
SRD5A1	0.023707
SRSF3	-0.023667
SOCS2	-0.023604
CST3	0.023558
GALNT11	-0.023537
OLIG1	-0.023489
TPMT	-0.023473
CIART	-0.023467
LY6E	-0.023341
ADRA1B	0.023294
QPCT	-0.023225
ZFYVE1	0.023180
WFS1	0.023169
PIP4K2A	0.023169
PLIN4	-0.023152
APRT	0.023150
CHAC1	-0.023121
CIDEA	-0.023118
FGFR1OP2	0.023117
CPQ	-0.023082
UHMK1	-0.023035
SLC26A6	0.022996
ZNF768	-0.022985
CD163	-0.022965
SPAST	0.022932
HBB	-0.022866
ZPR1	0.022782
IRF2	-0.022725
PIK3CA	0.022688
TMIE	-0.022656
TCTEX1D2	-0.022583
SNTB2	-0.022520
PPAT	-0.022436
USP30	0.022370
WDR46	0.022175
GATA6	-0.022141
CYP7A1	-0.022062
RCBTB2	-0.022021
FOXA3	-0.022004
NID2	-0.021967
SEPW1	-0.021946
PPARA	0.021931
C5orf28	-0.021906
NHLRC2	-0.021872
FAM115C	-0.021837
CER1	-0.021813
TWISTNB	0.021792
ZEB1	-0.021755
OCSTAMP	-0.021669
CCDC9	0.021662
C16orf54	0.021626
CHMP5	-0.021603
SOX9	-0.021593
ACSS2	-0.021589
ACTB	0.021569
ANXA4	0.021519
SLC16A13	0.021483
APOH	0.021434
LRIT1	-0.021427
EBPL	0.021353
MTMR9	-0.021302
PRRC2A	0.021256
ABCC3	-0.021247
IRF9	-0.021216
FST	-0.021128
FABP5	-0.021117
NNMT	-0.021113
ALDH3A2	0.021105
WLS	-0.021077
RPL30	-0.021039
WDR83OS	-0.020979
MMRN2	-0.020955
MTFR1L	-0.020926
SRSF7	-0.020854
DIO1	0.020820
IFI35	-0.020804
CLDN2	0.020795
LPAR6	-0.020782
PDCL3	-0.020771
KDM4D	0.020767
INSIG2	0.020763
EDN1	-0.020750
RUSC2	-0.020738
MR1	-0.020702
RARRES2	0.020688
LEPROTL1	0.020659
RNASE4	0.020648
ZNF665	-0.020632
CDCA7	-0.020627
GGT6	-0.020619
MBNL2	-0.020615
SERINC2	0.020609
ECI2	0.020589
CWC22	0.020579
ST5	0.020549
LRG1	0.020546
SNW1	0.020509
CENPL	0.020496
RASL11B	-0.020479
RAF1	0.020398
G6PC	-0.020362
EEF1B2	-0.020353
PYCR2	0.020317
DUSP1	0.020311
SOX7	-0.020282
MARCO	-0.020263
SAA1	0.020238
GPC6	-0.020185
INHBE	0.020164
HP	0.020145
CD300LG	-0.020145
LSM3	-0.020135
NAT2	-0.020130
FAM171B	0.020086
IRGC	-0.020064
MANBAL	0.020051
ULK4	0.020018
DCAF15	0.020000
ICMT	0.019993
NEIL1	0.019993
OCLN	-0.019991
CYTIP	0.019971
UCHL3	-0.019964
ENTPD2	0.019950
TTLL9	-0.019910
HDAC8	-0.019907
FZD7	-0.019871
FDPS	-0.019870
C5	0.019856
TREH	0.019797
RGS16	-0.019788
EMC9	-0.019783
GMPPB	0.019781
GPC1	-0.019776
CYB561	0.019776
SDS	-0.019772
CCDC3	-0.019747
SPN	-0.019745
S100A1	-0.019725
SIRPB1	0.019707
HIST1H2BN	0.019696
SLCO2A1	-0.019660
TRPC6	0.019644
NHLRC1	-0.019624
AMBP	0.019531
GADD45A	-0.019530
B3GALT6	-0.019502
SYNDIG1L	0.019498
PDCD10	-0.019465
HEXIM1	0.019456
STAT1	-0.019450
DCUN1D1	-0.019439
FMO4	-0.019430
TM6SF2	0.019410
PAIP2	-0.019391
MTMR10	0.019387
MAS1	0.019386
THSD1	0.019385
HIST1H4L	0.019362
CTSV	-0.019351
NOSTRIN	-0.019349
HIST2H2AB	0.019318
PDE7B	-0.019318
RGS4	0.019298
OAS1	-0.019294
SPATA2L	-0.019269
SLC35E4	0.019240
UBE2D3	-0.019211
ROR1	-0.019193
FERMT1	0.019169
TNFSF18	0.019119
ZNF608	-0.019108
COASY	0.019103
CCBL1	0.019077
ALKBH5	0.019069
HIST4H4	0.019048
GDF15	0.019035
CMAS	0.019012
CHCHD7	-0.018965
PTPN1	0.018964
TADA1	-0.018951
SLC6A13	0.018905
DNTT	0.018887
HIGD1C	-0.018880
PUS3	-0.018878
S100A8	-0.018862
ACTN1	0.018857
TJP2	0.018854
MID1IP1	-0.018851
AK3	-0.018814
DHCR7	-0.018796
PPM1G	0.018781
IKBKE	0.018772
TMEM135	-0.018759
SLC39A11	-0.018724
SPATA24	-0.018703
HSPA4L	-0.018701
ORAOV1	0.018693
USP38	0.018690
NPM1	-0.018666
STK11	0.018663
SULT1C2	-0.018656
CRY2	-0.018654
FAM129B	-0.018639
CAMTA2	0.018630
ZMAT1	-0.018630
RMND5A	-0.018592
RAPGEF4	-0.018565
MEOX1	-0.018559
RASSF4	0.018555
FDXACB1	-0.018544
CLEC4C	0.018535
AGFG1	-0.018531
DYNC1H1	0.018521
NOX4	-0.018517
BCAP29	-0.018504
TMEM43	0.018489
FUBP3	-0.018486
NFE2L1	0.018477
CFB	0.018445
SLC38A7	-0.018443
SOX18	-0.018439
ERAS	0.018422
G0S2	0.018416
TNFAIP8	-0.018379
MTUS2	0.018364
DCP1B	-0.018364
C14orf169	-0.018361
SMARCC2	0.018351
ALKBH4	0.018342
DDX20	-0.018332
AGPAT4	-0.018326
LTBP2	-0.018302
ZNF775	-0.018301
PLTP	-0.018289
ETAA1	-0.018264
HACE1	-0.018262
HSPH1	0.018250
ZFHX2	0.018244
SLC15A2	0.018211
TMEM55A	-0.018198
ORMDL3	0.018184
ZBTB22	0.018163
MTF2	-0.018162
DNASE2	-0.018139
ARL6IP6	-0.018139
AMER2	-0.018088
PDE5A	-0.018067
PTGES3	-0.018061
CCDC97	-0.018041
TMEM39A	0.018038
PLA1A	-0.018032
MCM7	0.018030
JUN	0.018029
SPAG7	0.018027
SUB1	-0.018026
VWA5A	-0.018016
SOCS5	-0.018012
NFIL3	0.017990
SPRYD4	-0.017982
CPXCR1	0.017978
GALE	0.017966
LSS	-0.017960
CARD11	0.017874
PCID2	-0.017861
PDZD8	-0.017858
CCDC84	0.017849
HLA-DRB5	0.017844
FCHSD2	-0.017844
BRD2	0.017843
TPO	0.017838
SYVN1	0.017832
EIF4A2	-0.017818
C9orf142	0.017809
CRYM	-0.017805
KIF1C	0.017787
CDH5	-0.017769
VLDLR	0.017769
AHDC1	-0.017745
FGG	0.017739
WDR55	-0.017721
SLC25A45	0.017711
SLC30A1	-0.017701
BMP4	-0.017701
PLCG2	0.017689
THRSP	-0.017687
CHST2	-0.017687
RNF224	0.017676
ATP6V1D	-0.017674
CCDC28A	0.017662
SLC35A1	-0.017628
RAB13	-0.017619
GMPPA	0.017567
PSEN2	0.017566
IFIT3	-0.017566
ZNF175	-0.017533
PDPK1	0.017520
EDNRB	-0.017510
NME3	0.017496
DAP	0.017494
S1PR5	-0.017484
SERPIND1	-0.017476
SQLE	-0.017473
CABS1	0.017467
SPP1	-0.017444
LUM	-0.017444
GNA12	0.017440
PEX26	-0.017408
SLC51B	0.017400
ABCG2	-0.017398
DMBT1	0.017376
APOA1	0.017354
DECR2	0.017344
JUNB	-0.017341
PARP16	0.017337
GZF1	-0.017288
PMP2	0.017248
LGALS3BP	-0.017230
CCNL1	0.017193
MLH1	-0.017189
AMIGO2	-0.017179
LRRC59	0.017165
TPR	-0.017162
CCDC64B	-0.017154
TJP3	0.017134
CHMP7	0.017132
DEPTOR	-0.017125
RDH14	-0.017120
IRGM	-0.017098
PGM5	0.017098
FAM83A	-0.017086
ATP1B4	0.017057
AARD	-0.017042
RNF123	0.017042
CBFB	-0.017026
SLC17A5	0.017025
THAP3	-0.017014
LDHD	0.017005
RIBC1	-0.016986
DHX37	-0.016973
NR5A2	-0.016970