!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!old	61-67
!young	52-56
!cell_type	CD4+lyphocytes
!age_unit	year
!organism	human
!end_metadata
HLA-DRB1	0.053635
BIRC3	-0.051807
HLA-A	-0.050888
SLC39A8	0.048839
GNLY	0.046824
GNLY	0.043308
MT1E	0.041445
PTPRC	-0.039443
PTPRC	-0.037975
MFF	0.037532
SPTBN1	-0.037038
S1PR5	0.036896
PRF1	0.035749
GZMM	0.035438
RPL14	0.034788
CD8A	0.034383
DKK3	0.034120
SPATA13	-0.033916
ZNF683	0.033370
C17orf97	0.033062
PHACTR2	-0.032893
IL36G	0.031954
MS4A6A	0.031906
MS4A6A	0.031650
IL1RN	0.031530
BASP1	0.030390
IDO1	0.030349
VRK3	-0.030302
ISG15	0.030207
FBXW7	-0.030086
LYZ	0.029970
CDK5RAP2	-0.028730
MCMBP	-0.028506
AIM2	-0.028289
NME4	0.028219
IFITM3	0.027854
MXRA7	0.027785
RNF19A	-0.027649
CYSLTR1	-0.027592
SIPA1L3	-0.027573
IFI6	0.027245
PPFIBP2	0.026898
GZMK	-0.026572
FOSB	-0.025702
LINC00339	0.025625
TSHZ2	0.025504
SDHAP1	0.025482
HLA-DRB3	0.025453
RPS23	-0.025438
ARID4B	-0.025421
KAT2B	0.025400
SPIN1	-0.025330
NKG7	0.025283
NBPF9	-0.025260
PCSK1N	0.025238
GRINA	0.025144
OR2A9P	0.025129
ADRA1D	-0.025084
SERPINB2	0.025039
YBX3	0.024997
DDX17	-0.024971
ITM2A	-0.024919
CD8A	0.024848
TSPAN18	-0.024627
RORA	-0.024452
LAMP3	0.024281
LOC729950	-0.024265
TBC1D2B	0.024256
MLH3	-0.024229
CD37	0.024130
MUC6	-0.024080
ZC2HC1A	-0.024074
GPR56	0.023984
CACTIN	0.023966
CXCR6	0.023957
MGRN1	0.023907
CEACAM22P	-0.023849
CLECL1	-0.023587
C6orf203	0.023473
CFB	0.023473
OSBPL8	-0.023468
XRN2	-0.023447
IRF7	0.023426
RGMA	-0.023399
IFI44L	0.023358
DCAF4	0.023287
PRAMEF5	-0.023281
CD3E	0.023141
LYZ	0.023023
GZMH	0.022996
OAS3	0.022957
SLA2	0.022934
TGFBRAP1	-0.022930
MRE11A	-0.022906
SLFN5	-0.022885
EBI3	0.022778
L1CAM	-0.022733
BCAS2	0.022683
SESTD1	-0.022680
UHMK1	-0.022669
S100A1	-0.022643
SLC7A11	0.022564
FCER1G	0.022507
GSTM3	0.022474
VAX2	-0.022396
CSF1R	-0.022380
AGFG1	-0.022331
XAF1	0.022309
DFNA5	0.022210
RPS26	0.022080
NDRG3	0.021969
SERPINB9	0.021956
GREB1	-0.021949
YWHAE	0.021928
GOLGB1	0.021898
GRINA	0.021878
LMNA	-0.021850
YWHAH	-0.021845
FEV	-0.021669
SERPINE2	-0.021656
ANTXR1	-0.021650
SLC5A3	-0.021631
IKZF3	-0.021614
RABEP1	-0.021607
CCDC86	0.021558
GPR119	-0.021556
RBAK	-0.021522
MS4A6A	0.021478
TNFSF14	0.021462
SGK3	-0.021444
DTNBP1	0.021432
CREBBP	-0.021422
NSUN6	-0.021353
DSTYK	0.021260
SNRNP25	0.021229
C17orf97	0.021188
RND2	-0.021166
FAM53B	0.021134
LACTB	0.021107
CNOT3	0.021095
BTN3A2	0.021075
SLC7A5	-0.020985
CLSPN	-0.020975
MAS1	-0.020875
FGFBP3	-0.020762
ARHGEF35	0.020727
SLC25A36	-0.020681
PMAIP1	-0.020660
TMPRSS3	0.020652
NUPL1	-0.020626
GTSF1	0.020599
CEBPA	0.020583
SERPINB2	0.020559
CCDC94	-0.020550
FAM65C	-0.020549
TAOK1	-0.020535
CYP1B1	0.020528
BZRAP1	0.020516
NDUFS1	-0.020490
SPI1	0.020486
RPSA	0.020486
HLA-DPB1	0.020484
KCTD13	0.020481
VAV1	0.020429
ACTN1	-0.020424
PRMT2	0.020408
NFKB2	0.020378
EED	0.020340
CCR2	-0.020339
CRACR2B	-0.020292
TSPYL2	0.020272
TMEM63B	0.020234
ANXA7	-0.020221
CDC34	0.020200
CD151	-0.020166
ZNF512B	-0.020138
ZRANB1	-0.019939
CRYBB2	0.019901
SLC28A1	-0.019872
RAD21	-0.019849
SERINC3	-0.019836
DYNLL1	0.019827
ABCA1	0.019808
TNS3	0.019790
INTS8	0.019784
FAM86A	0.019779
IL32	0.019770
RPS26P11	0.019757
MYBPC1	-0.019754
NFIC	-0.019743
FGFBP2	0.019727
MX2	0.019691
IL1A	-0.019675
REL	0.019616
RENBP	0.019607
EPHX2	0.019603
CPSF1	-0.019585
HOXA6	-0.019566
UBAP2	0.019537
ZHX2	-0.019529
TRAT1	-0.019515
RBM12B	-0.019427
IFNL2	-0.019413
RSAD2	0.019409
SPRYD3	-0.019393
NME1	0.019333
CX3CR1	0.019331
TRAF1	0.019319
ARID4B	-0.019313
DKK3	0.019310
MAPK4	-0.019284
POU2F2	0.019107
SWI5	0.019104
FGF9	0.019100
CCDC102A	0.019085
TMUB2	-0.019069
MLX	0.019065
CXCR4	-0.019050
SASH1	0.019039
CA11	0.019036
DHX58	0.019005
ERGIC1	0.018970
DOK2	0.018953
GSKIP	-0.018939
IL27RA	0.018870
CTSZ	0.018850
EVI2A	-0.018815
SRM	0.018790
OR1Q1	-0.018759
VPS13C	-0.018753
BTN3A3	0.018736
CXCR5	0.018722
PLA2G4C	0.018714
CCL5	0.018705
TSNAX	0.018699
CD1C	-0.018662
RFX1	0.018639
PRPF31	0.018607
CELA3B	-0.018604
SH3KBP1	-0.018581
PFDN6	0.018567
SPATA7	-0.018555
SOS1	0.018535
CTNNAL1	-0.018529
ARHGAP11A	-0.018501
CDK5R1	-0.018466
TNIP3	0.018418
NTPCR	0.018338
NME7	0.018335
FGL2	-0.018330
GPR56	0.018289
MORC2	0.018286
JARID2	0.018267
GRHPR	0.018256
GADD45B	0.018242
RNF126P1	-0.018232
EXOSC4	0.018222
PHF1	0.018219
OR7D2	0.018208
TMEM128	0.018194
SERPINB7	-0.018193
POLR2M	-0.018165
CD3G	-0.018145
PRCP	0.018118
PELP1	0.018093
HSD17B12	-0.018081
HDGFRP3	0.018058
CHURC1	0.018051
HLA-DRB5	0.018032
CCDC120	0.018025
PWWP2B	0.018019
WIPI1	0.018005
MYOF	0.017983
TNFRSF18	0.017971
OR52D1	-0.017956
MVB12B	0.017951
PTPRA	-0.017943
GABARAPL2	0.017931
KRT23	-0.017922
HMOX1	0.017897
SASH1	0.017861
CPM	-0.017857
PTK2B	0.017846
ATXN2L	0.017836
PHGDH	-0.017832
ERAP2	0.017829
BSG	0.017824
NSRP1	0.017816
ESM1	-0.017808
RTN1	0.017801
H2AFX	0.017800
LSP1	0.017798
BCR	0.017795
GNL3L	-0.017791
PLD3	-0.017788
KCNC4	-0.017779
FUNDC1	0.017773
SLC43A2	-0.017767
FBXW8	-0.017764
DCAF15	0.017747
PHF20L1	-0.017732
CLIC5	-0.017726
S100A12	0.017701
ZNF618	-0.017669
FAM20C	0.017656
MATK	0.017651
SLC22A5	0.017637
RP1L1	-0.017622
TOP1MT	0.017614
OR1L8	-0.017600
ADARB2	-0.017600
TAGLN	-0.017596
DNAJB14	-0.017595
CNST	-0.017589
SOX30	-0.017589
TOX4	0.017453
PURG	-0.017431
CDK5RAP2	0.017410
ATP6V0B	0.017388
AAK1	-0.017387
HIVEP1	0.017378
USH1G	-0.017343
PIGF	0.017340
CD74	0.017335
APOC3	-0.017317
STARD3	0.017307
TXLNG	-0.017284
BCLAF1	-0.017269
HOXB1	-0.017265
TSC22D4	0.017225
RCE1	0.017193
RTN2	-0.017164
GHDC	0.017160
GPR68	0.017155
PFN1	0.017155
PSORS1C1	-0.017143
TMEM151A	-0.017137
ABCF2	0.017090
PLCL1	0.017077
SCGB3A1	0.017077
ARL14EP	-0.017074
KIAA0907	0.017064
CXCL1	-0.017053
INPP5E	0.017026
SF3B6	0.017010
CBX4	0.017005
LTV1	0.017001
SF3B1	-0.016973
IKZF1	-0.016969
RLN2	0.016969
TARP	-0.016958
SNORA64	-0.016958
SRSF6	-0.016943
AGAP7P	-0.016943
CFAP44	-0.016914
PCDHGB6	-0.016904
SPINK1	0.016896
ASUN	0.016896
TUBA1A	-0.016894
FAM107B	-0.016877
GNLY	0.016842
PPP2R5C	-0.016837
MED12	0.016833
SRI	0.016824
VRK3	-0.016817
CBX3	-0.016814
PLCG1	0.016806
ACOT9	0.016800
CAPN10	-0.016794
HCN4	-0.016777
NDUFS2	0.016767
GRN	0.016763
ARFIP1	-0.016757
DGKA	0.016750
KCNK10	0.016747
PCED1A	0.016745
ABCA12	-0.016735
STIM1	0.016718
PAK4	-0.016686
DNASE1L1	0.016685
OR4F21	-0.016679
HYPK	0.016673
TNFAIP8L1	-0.016672
LOC100506136	-0.016671
FBRSL1	0.016671
PRKAR1A	-0.016662
HERC6	0.016662
KLHL5	0.016654
BMP2K	0.016631
SMG9	0.016589
BCL3	0.016581
NAAA	0.016580
MTX2	0.016576
BMI1	-0.016572
CBX7	0.016565
CBWD5	0.016560
CECR1	0.016541
KXD1	0.016540
SULT1A2	0.016520
HSBP1	-0.016516
TP53	0.016508
LPPR1	-0.016506
MLKL	0.016506
GGA1	0.016495
TUBA1C	-0.016473
DTNBP1	0.016461
ZNF557	0.016446
SOX13	-0.016438
DCTN1	-0.016434
ATXN2L	0.016429
GUCA1B	0.016427
CEP85L	-0.016425
ZYX	0.016422
PHLDB1	-0.016420
LAGE3	0.016401
REL	0.016397
RECQL	-0.016362
RUNX1T1	-0.016353
CENPT	0.016322
PKD1	0.016316
JSRP1	0.016315
FAHD1	0.016314
YEATS4	0.016290
MATR3	-0.016285
ZNF586	-0.016271
DDX43	-0.016268
ST6GALNAC1	-0.016223
PLCH2	-0.016214
NFKBIB	0.016212
H1F0	0.016203
SPTBN1	-0.016196
KRT9	-0.016175
FEZ1	0.016171
TAF15	0.016162
TOMM5	0.016153
SOX8	-0.016150
ADAM7	-0.016146
SELT	-0.016138
NCF2	0.016134
TMEM120A	0.016133
PREX1	0.016128
AGAP1	0.016123
GALE	-0.016080
INSIG1	-0.016074
REG3G	-0.016071
FAM96A	0.016068
TMEM86B	0.016064
STAG2	-0.016038
CAPZB	0.016033
PCYT2	-0.016033
CNGB1	-0.016019
EZR	-0.016014
SIAH1	-0.016013
CORO1C	0.016013
RAB6A	0.016002
OSBPL7	0.016002
DPM3	0.015996
STRN3	-0.015994
ANXA11	-0.015979
PRR16	-0.015977
DIXDC1	-0.015966
HOXC6	-0.015963
PHACTR1	0.015962
GOLGA8B	0.015961
LTBP4	0.015949
NUFIP2	-0.015942
GAK	-0.015936
IQCG	0.015931
LY6E	0.015921
LILRA4	-0.015920
SLC4A2	0.015900
LRRN3	-0.015891
APOM	0.015880
AHI1	0.015855
BFAR	0.015847
VASH1	-0.015846
EZH2	0.015843
FHL3	-0.015835
SNX16	-0.015809
KHNYN	0.015799
IKZF3	-0.015788
MAPK15	-0.015779
ELMO1	0.015778
LRRC32	-0.015758
VSX2	-0.015753
DDX26B	0.015753
CAPZA2	-0.015730
TTC31	0.015728
DBNL	-0.015724
C2orf74	0.015722
IFIH1	0.015720
YTHDF1	0.015719
VWA7	-0.015718
R3HCC1	-0.015718
C19orf43	0.015700
VPS51	-0.015700
AARS	-0.015673
CLCA4	-0.015666
ZNF702P	-0.015665
KLRF1	0.015659