!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Doxycycline
!smiles	CC1C2C(C3C(C(=O)C(=C(N)O)C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)N(C)C)O
!drugbank_id	DB00254
!pubchem_cid	5281011
!cell_type	Embryoid bodies -  24 Hours
!organism	mouse
!end_metadata
F2R	0.186996
HPRT1	0.180780
TDGF1	0.162549
EOMES	0.134248
SLC7A3	-0.104496
ABCC4	-0.096710
DPYSL2	0.095889
RBBP7	0.094452
RPL10A	-0.093850
APOE	-0.092090
DLL3	0.091300
CHCHD10	-0.090627
PGK1	0.089109
FSTL1	0.087262
SOX2	-0.083421
ID1	0.082667
LEFTY2	0.081898
HSPE1	-0.078477
SRM	-0.078432
GSTP1	-0.075266
LDHB	-0.074298
PPIA	-0.073130
NSFL1C	-0.072345
IFITM3	-0.069281
NHP2	-0.069208
TUBA1A	0.067766
CBR3	-0.066850
SET	-0.066156
DPPA4	-0.064996
HSPD1	-0.064949
TPI1	0.063553
CDH11	0.063202
ERH	-0.062890
ATP6V0C	-0.062631
FN1	0.061650
TCEAL8	0.061439
RPS12	0.061015
RPS20	0.060838
HSP90AA1	-0.059676
LDHA	0.059117
HSPB1	-0.058729
RPL7	0.058648
SENP3	-0.058548
PHLDA2	0.058321
PNP	-0.058314
NOP58	-0.057759
G3BP2	-0.057709
DPY30	-0.057460
RPL8	-0.056863
RPL3	0.055947
ZFP42	-0.055908
SLC27A2	-0.055649
PROM1	0.055458
NR0B1	-0.055259
GPX4	-0.054752
CTBP2	-0.054735
POU5F1	-0.053720
SUMO2	0.053294
RPL18A	-0.052956
FNTA	-0.052758
TUBA4A	-0.052709
ABRACL	0.052698
DHX16	-0.052120
METTL9	0.052070
SGK1	-0.051708
LRRC58	0.051528
ASNS	0.051423
RBPMS2	-0.051376
DPPA2	-0.051255
SMAD1	0.050951
APLNR	0.050714
HINT1	-0.050338
PHC2	0.050014
RPS4Y1	0.049429
OTX2	-0.049111
LAMP1	-0.049037
GALK1	0.048758
NOP10	-0.048703
PYCR2	0.047941
TRIM28	-0.047579
PABPN1	-0.047159
FSCN1	0.047123
EIF4A1	-0.046782
SNX2	0.046140
FAM162A	0.045825
CYP26A1	0.045790
CYB5A	-0.045711
PRICKLE1	0.045701
MSH6	-0.045666
RAN	0.044782
SLC25A3	-0.044697
AP3S1	0.044184
PITX2	0.044008
SFXN1	0.043770
RPL22	0.043419
FABP7	0.043331
RPS13	0.043165
PTGES3	-0.043108
GLDC	-0.043060
TAGLN	0.042158
CDH1	-0.042125
MDK	0.042100
BNIP3	0.042087
RBP1	0.041945
AJUBA	-0.041717
PGAM1	0.041711
CYCS	0.041478
COX7A2	-0.041103
SRRT	-0.041095
NACA	0.040984
CNN3	0.040720
DUSP6	0.040488
AKAP12	-0.040421
MYADM	0.040345
APRT	-0.040345
CACHD1	0.040319
RPS11	-0.040297
CD9	0.040116
GCLM	-0.040090
MRPS24	-0.039975
MKRN1	-0.039907
BAX	-0.039605
MREG	-0.039495
DOCK11	0.039118
EEF1B2	0.039094
SLC25A4	0.038967
MCL1	-0.038814
CCT2	0.038676
PCNA	-0.038538
ERAS	-0.038366
SEC61G	-0.038300
DDIT4	0.038299
RPS8	-0.038278
HMGN1	0.038217
SNRPD2	0.037969
SNRPF	0.037654
TUBA1B	-0.037312
NANOG	0.037234
PCBP1	-0.037194
PSME2	-0.037139
CLDN7	-0.037096
NAF1	-0.036978
SH3BGRL	0.036951
RFC5	-0.036734
PRMT1	-0.036686
NDUFA12	0.036377
RPL7A	-0.036184
LIMD2	0.035939
SNX17	0.035794
PPIB	0.035793
DSTN	-0.035661
CSRP2	-0.035627
CFL1	-0.035551
RPL13A	0.035529
HNRNPA2B1	-0.035493
FABP5	0.035235
IGFBP2	-0.035201
RPS19	0.035134
KLF2	-0.034930
DACT1	0.034914
IFI30	-0.034742
S100A10	0.034679
PMM1	-0.034648
CA2	-0.034457
TIMM23	-0.034430
EIF3I	0.034372
C1QBP	-0.034355
FAU	0.034254
HNRNPF	-0.034253
AHCY	-0.034210
QDPR	-0.034160
ALDOA	0.033944
PHLDB2	0.033729
C11orf31	0.033629
FAM60A	-0.033568
CIRH1A	-0.033414
ATP6V0D1	-0.033304
KRT8	0.033265
RPS10	0.032978
PIM2	-0.032955
FTL	-0.032891
SALL4	0.032859
GRN	-0.032678
SOCS2	-0.032625
TWF2	-0.032566
FMNL2	0.032559
NUP37	-0.032495
CLIC4	0.032411
SHFM1	0.032293
CDC34	-0.032098
GJA1	-0.031936
EPCAM	-0.031812
EZH2	0.031708
RPS24	0.031544
TEAD2	0.031362
ACTN4	-0.031358
POLR2K	-0.031348
SLC25A5	-0.031098
T	0.030989
PSME1	-0.030807
LHX1	0.030805
LAMTOR5	0.030805
FABP3	-0.030520
YBX3	-0.030422
PKDCC	0.030353
ETV2	0.030222
PRTG	0.030133
RNPS1	0.030039
SMARCD2	0.030036
DDT	-0.030034
ATP6V1F	-0.029837
MCF2	-0.029808
TCFL5	-0.029808
TALDO1	-0.029685
AIMP1	-0.029612
IVNS1ABP	0.029592
NDUFC1	0.029577
HSPA4	-0.029572
DCTPP1	-0.029362
CDCA5	-0.029317
PXDC1	0.029303
HNRNPA0	0.029228
BCAT2	-0.029184
MKI67	0.029032
DNAJC7	-0.029032
HSP90B1	0.029029
UQCRC2	0.028995
RCN2	0.028960
KIF20A	0.028908
ZBTB8A	-0.028858
TCP1	0.028796
RPL35	0.028790
GNG10	0.028760
ATF1	-0.028719
BCCIP	-0.028611
APEX1	-0.028575
CDH2	0.028572
COTL1	0.028509
TMA7	-0.028378
RPL36AL	-0.028376
UBA2	-0.028335
HNRNPK	0.028263
STIP1	-0.028148
MORC1	-0.028091
ODC1	-0.027835
EIF3F	-0.027821
MRFAP1	0.027753
LBR	0.027742
KIAA0101	0.027729
HSP90AB1	0.027630
SNRNP40	0.027614
CPE	0.027484
IGFBP4	0.027478
AKR1B1	-0.027418
GCSH	-0.027384
CA4	0.027364
MRPL45	-0.027342
ENOPH1	-0.027250
CNIH1	0.027213
GLO1	-0.027182
VPS26A	-0.027096
MIXL1	0.026998
RRM2	0.026979
VBP1	0.026850
PSMC4	-0.026764
HES6	0.026758
RPS27L	-0.026751
KCTD6	0.026708
SDC4	-0.026668
RRN3	-0.026579
DUSP1	-0.026544
ID3	0.026525
SSSCA1	-0.026518
RBMS1	0.026464
RPL26	0.026376
RNF149	0.026334
RANBP1	-0.026285
ALPL	0.026244
ZBTB18	0.026237
SNRPD1	0.026234
DUSP9	0.026063
LEF1	0.026038
UTF1	-0.025984
UTP3	0.025938
CLPP	-0.025742
RDX	0.025739
DDX39A	-0.025721
PPP1CB	0.025698
HSPA5	0.025618
FNIP2	-0.025617
SQLE	-0.025608
RPL15	0.025603
ATP5O	0.025551
TFE3	-0.025542
MTHFD1	-0.025524
CCNB2	0.025514
MARCKSL1	0.025316
OOEP	-0.025295
SNX24	0.025184
ARL6IP6	0.025181
ATP6V1C1	-0.025154
ALDH9A1	-0.025089
BEND3	-0.025057
PAICS	0.025042
MTM1	0.024970
SRSF3	0.024918
MCM6	0.024913
SIRT1	-0.024834
AP1M2	-0.024689
PPIC	0.024501
HMGB2	0.024494
CCNB1IP1	-0.024483
HMGCS1	0.024474
TRH	-0.024425
C11orf73	-0.024423
TJP1	0.024419
CLDN6	-0.024335
ENAH	-0.024321
IGF2	0.024280
TMEM126A	-0.024258
CRMP1	0.024224
CCNG1	-0.024109
KDM1A	0.024105
PEG3	0.024063
CHCHD4	-0.024003
ZSCAN10	-0.023989
UBE2E3	0.023939
ARL3	0.023905
KIAA1551	-0.023792
ASNA1	-0.023790
SLC2A1	0.023747
PFN1	-0.023689
AURKAIP1	-0.023564
PDPN	-0.023541
PISD	-0.023540
KLHDC3	-0.023505
LGALS3	-0.023377
ATP5J	-0.023350
TES	0.023336
MAGOH	0.023291
ATOX1	-0.023280
GABARAP	-0.023245
ACTN1	0.023089
GNL3	-0.023049
RAPGEF2	0.023033
PA2G4	-0.022960
UPP1	0.022926
GPI	0.022917
ATP6V1D	-0.022880
MOGAT2	0.022767
KCNK1	-0.022761
RAB1A	-0.022737
RPS27A	0.022719
ASAH1	-0.022702
MCM4	0.022680
NDUFS2	-0.022657
C4orf27	-0.022641
KHDRBS1	0.022603
CSTB	-0.022592
DCAF4	-0.022588
SMAD4	0.022571
H2AFV	0.022562
ST13	-0.022540
MRPS18B	-0.022458
RPS28	0.022430
UBE2E1	0.022406
VDAC3	0.022385
SLC7A5	0.022365
SNRNP25	0.022336
SCPEP1	-0.022253
RHPN2	0.022229
TIPIN	-0.022185
CLK1	-0.022175
TMX1	0.022162
NOP2	-0.022121
WDR6	0.022029
AMOT	0.022005
FDPS	0.021997
STX3	-0.021989
DPPA5	0.021964
REST	-0.021920
GLUL	0.021881
MAT2A	-0.021875
SLC38A2	-0.021862
DTYMK	-0.021824
MID1IP1	-0.021695
NCL	-0.021636
SLC20A1	-0.021614
CCT3	-0.021612
LPHN2	0.021576
CDC42EP4	0.021534
PXDN	0.021406
MYBBP1A	-0.021370
BNIP3L	0.021328
ATP5G1	-0.021319
PSAT1	0.021302
ZNF281	-0.021298
PSMB10	-0.021289
ACSL4	-0.021234
AHSA1	-0.021209
PEX7	-0.021176
PAM16	0.021029
GREB1L	0.021019
JADE3	-0.021004
EEF2	0.020876
KIAA0196	-0.020838
ISYNA1	-0.020836
TEX10	-0.020813
MPHOSPH8	-0.020776
PHGDH	0.020773
COX7A2L	0.020768
DNMT3L	-0.020760
PSMC3	-0.020743
SLC6A15	-0.020651
RPS26	-0.020597
EMG1	-0.020597
ATP5B	0.020589
PSMD1	-0.020532
WDR45B	0.020529
AASS	-0.020518
MYL12B	0.020506
UQCRC1	-0.020504
OAZ1	0.020468
VPS35	-0.020427
GSTM1	-0.020405
PSMB5	-0.020388
JARID2	-0.020372
GTF2E2	0.020338
NUAK1	0.020254
FHL1	0.020254
FH	0.020242
HNRNPDL	-0.020185
PIK3CD	0.020176
CD81	-0.020126
SLC9A3R1	0.020121
ARPC3	-0.020038
LYPLA1	-0.019967
SUB1	-0.019953
PCBP4	0.019900
CNPY2	0.019891
LGALS1	-0.019872
SP5	0.019862
GDI2	0.019829
SPNS1	-0.019806
TUBB6	0.019787
CBX3	-0.019761
DDX39B	-0.019758
MEX3B	0.019682
MDH1	0.019625
H2AFZ	0.019610
MRPS33	0.019543
TIMM8A	-0.019534
MTCL1	-0.019527
ATP5D	-0.019514
CCT6A	-0.019470
NOTCH3	0.019460
SLC35D3	-0.019457
GID8	-0.019437
FAM169A	-0.019399
TSPAN3	0.019397
COQ7	0.019390
RCC2	-0.019368
MAPKAPK3	-0.019338
FGF5	-0.019334
C9orf41	-0.019328
MRPS18C	-0.019294
CST3	0.019282
RPS21	0.019240
NODAL	-0.019236
PNO1	-0.019225
IRF1	-0.019175
MRPL42	-0.019172
PLP2	0.019164
H2AFY	0.019120
SSR2	-0.019114
KRAS	-0.019103
KLF9	-0.019087
H1F0	0.019030
GNPDA1	-0.019018
MYRF	-0.019009
PFAS	-0.018986
DNMT3B	-0.018975
NUDT21	0.018958
COX6B1	0.018937
TMEM261	-0.018887
PHLDA1	0.018829
MCM3AP	-0.018817
UTP14A	-0.018808
RPL18	0.018773
REXO2	-0.018745
TOMM20	0.018743
RAP1A	0.018734
MARS	0.018713
KCTD3	-0.018698
SAR1B	0.018688
SALL2	-0.018685
SERPINH1	0.018656
CTU2	-0.018608
PRDX1	0.018585
CTH	-0.018573