!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!gene	SIRT1
!cell	Liver
!perturbation	SRT1720, SIRT1 Activator
!disease	High-fat diet - 30mg/kg 
!end_metadata
GADD45G	0.120864
RGS16	-0.101994
ESM1	-0.096547
SLC25A25	0.091381
CYP1A2	0.083840
CYP17A1	-0.083466
PHLDA1	0.075908
ERRFI1	0.071544
PLK3	0.070801
LYVE1	-0.069832
FOXQ1	0.069149
LCN2	-0.061739
S100A8	-0.060570
CISH	0.060431
ANXA2	-0.059654
THRSP	-0.057775
SLPI	-0.057662
SAA1	-0.053591
CIDEC	-0.052301
PF4	-0.051158
ELOVL6	-0.050271
DUSP1	0.049833
IGFBP2	0.049618
LY6D	-0.047544
LGALS1	-0.047444
SPINK1	-0.047422
CCDC80	-0.046995
SOX18	-0.046079
HAO2	-0.045430
PPP1R3C	0.044690
ACOT1	-0.044619
RBP1	-0.044603
CYP7B1	0.043909
S100A9	-0.043712
CD93	-0.043685
COL4A1	-0.042955
G6PC	0.042841
HK2	-0.042575
APOA4	-0.042438
ELOVL3	0.041722
IGFBP5	-0.041294
DBP	-0.041072
INHBB	-0.041033
GSTA5	-0.040585
HBB	-0.040441
SDPR	-0.040243
COL4A2	-0.039901
NT5E	-0.039675
TCEAL8	-0.039327
TXNIP	-0.039226
HHEX	0.038148
EMCN	-0.038029
GPR182	-0.037519
ATP6V1H	0.037023
S100A6	-0.036936
SUSD4	0.036881
ANGPT2	-0.036862
NENF	-0.036437
SPP1	-0.036264
FCER1G	-0.036157
UBD	-0.036093
GPX3	-0.035654
AACS	-0.035559
CCRN4L	0.035558
SPARC	-0.035546
MMRN2	-0.035544
HES1	-0.035467
ACER2	-0.035305
UGT2B17	0.035154
CHKA	0.035109
ESAM	-0.034925
DYNLL1	-0.034770
OAT	0.034694
C8B	0.034685
GSTP1	0.034509
MEST	-0.034384
AVPR1A	0.034223
ST3GAL5	-0.034145
ALDH1B1	-0.034021
PPIC	-0.033954
H19	-0.033951
RNASE4	0.033946
PKM	-0.033913
CSRNP1	0.033879
ANXA5	-0.033847
BMPER	-0.033816
GAS6	-0.033767
NRARP	-0.033712
CBR1	-0.033697
SDR9C7	0.033589
NPR2	0.033586
CLDN1	0.033470
CRELD2	-0.033381
HIST1H2AG	-0.033222
VIM	-0.033208
CAT	0.033029
ROBO1	-0.033002
NUDT7	0.032781
CD300LG	-0.032707
ICAM2	-0.032628
ID2	0.032380
NID1	-0.032246
TNFRSF11B	-0.032133
C1QC	-0.032016
PLTP	-0.031981
PLAC8	-0.031930
TTC39C	0.031901
IGFBP1	0.031749
CYBA	-0.031707
FHL1	-0.031598
MFGE8	-0.031592
EMP1	-0.031570
FGF21	-0.031510
WBP5	-0.031460
CYP4V2	0.031359
CSTB	-0.031172
RAMP2	-0.031097
LBH	-0.031052
GPX8	-0.031051
WFDC1	-0.030964
GPLD1	0.030886
IL1B	0.030869
C10orf10	-0.030759
RAPGEF5	-0.030727
GSTM1	-0.030723
MGST3	-0.030708
TOB1	0.030572
HSPH1	-0.030548
RPS15	-0.030516
VCAM1	-0.030515
TOMM7	-0.030337
LGALS3	-0.030133
ITPK1	0.030076
HEY1	-0.030070
ID1	-0.029773
CD9	-0.029681
STAB1	-0.029679
CDH1	-0.029657
SERPINA1	0.029620
HSPG2	-0.029609
HIST1H2AJ	-0.029589
ARNTL	0.029561
CLPX	0.029547
CD63	-0.029494
WSB1	0.029480
DMGDH	0.029468
MOGAT1	-0.029343
RAB31	-0.029166
FBXO21	0.029154
COL5A1	-0.028894
CYP2U1	0.028756
ANG	0.028743
TMEM45B	-0.028697
AKAP12	-0.028675
GCLC	0.028615
NTRK2	-0.028576
ANGPTL4	-0.028494
NDUFA3	-0.028464
ARMCX1	-0.028440
CYP8B1	0.028350
PAICS	0.028332
PRSS8	-0.028288
CMTM3	-0.028207
BHMT	0.028182
CCND1	-0.028154
MKNK2	-0.028150
DCTN1	-0.028125
RNF145	-0.028116
CA3	0.028052
CES3	0.028048
COX20	-0.028039
DPM3	-0.027999
DDX3X	0.027995
FSTL1	-0.027955
KCNJ8	-0.027944
CD207	-0.027942
CYP4A11	-0.027941
SLC35E3	0.027921
CFD	-0.027797
NDUFA12	-0.027789
HLA-DQB1	-0.027702
CYP4A22	0.027556
HIST1H2AM	-0.027414
GDF15	-0.027316
CELA1	0.027262
RGN	0.027215
LAMB3	-0.027123
MMP12	-0.027101
LPL	-0.027067
C12orf57	-0.027047
HMOX1	-0.027029
COTL1	-0.026855
FST	0.026847
PHPT1	-0.026836
IDI1	0.026760
DNAJB1	-0.026744
NDUFA2	-0.026685
SDCBP2	-0.026668
KLF9	0.026529
WFDC2	-0.026514
TYROBP	-0.026412
ADAMDEC1	-0.026382
CCDC120	-0.026339
PKIA	-0.026320
RGS10	-0.026279
VWF	-0.026250
G0S2	-0.026233
C1QA	-0.026226
ELL2	0.026161
AKR1C4	0.026111
GAL3ST1	-0.026043
SLC1A4	-0.025982
NOTUM	0.025945
TREH	-0.025805
MSRA	0.025792
GALK1	-0.025744
PON1	0.025738
LRIT2	0.025731
GRB10	-0.025719
CYSLTR1	-0.025709
CKB	-0.025703
ANAPC13	-0.025675
LRRC28	-0.025673
C5	0.025604
GADD45A	-0.025563
HSD3B7	0.025556
F11	0.025538
FHL2	-0.025429
RERG	-0.025424
NXN	-0.025398
F8	-0.025355
MRPS12	-0.025338
CDR2	-0.025337
MCAM	-0.025317
CRTAP	-0.025298
MRPL33	-0.025290
PCK1	0.025249
FAU	-0.025239
BHLHB9	-0.025226
PIGR	0.025160
FCGR2A	-0.025115
TIMP3	-0.025095
TMEM98	-0.025068
SERPINB6	-0.024957
SERF2	-0.024941
IL17RB	-0.024915
FKBP1A	-0.024860
HMGCS1	0.024847
TIMP2	-0.024831
PER2	-0.024814
CSRP1	-0.024772
C8A	0.024758
TAB2	0.024752
SNN	-0.024715
SYBU	-0.024675
COX17	-0.024656
LUM	-0.024606
TMEM86A	-0.024605
RGS5	-0.024588
SLC25A10	-0.024567
ACTB	0.024542
RPL38	-0.024523
FNDC3B	-0.024488
FAM180A	-0.024488
MLXIPL	0.024446
TSPAN7	-0.024442
PIGP	-0.024385
BLOC1S1	-0.024347
DAK	-0.024346
OLFML3	-0.024321
CD74	-0.024289
CASP1	-0.024255
SLC19A2	0.024241
SOCS3	0.024237
RPP21	-0.024163
GLTP	-0.024086
HINT3	-0.024062
SLIRP	-0.024060
PRC1	-0.023982
PGRMC1	0.023981
GMFG	-0.023949
MREG	0.023912
CYP4F12	0.023893
ABCB11	0.023873
C11orf24	-0.023848
IGFBP3	-0.023848
TBX3	0.023807
VEGFB	-0.023806
C19orf53	-0.023763
RPL12	-0.023685
LSM7	-0.023678
C1QB	-0.023644
PDPN	-0.023634
RPL30	-0.023611
CTSK	-0.023592
RPS10	-0.023569
FERMT2	0.023338
DNAJC4	-0.023304
CLEC6A	-0.023295
ARMCX2	-0.023273
TBCEL	0.023272
TIMP1	-0.023267
EVL	-0.023258
ACOT13	-0.023253
ARHGAP30	-0.023237
SNRPD1	-0.023157
HLA-DRB5	-0.023101
PRKCH	-0.023027
CXCL16	-0.022992
NCK2	-0.022974
FKBP7	-0.022940
TMEM178A	-0.022920
FITM1	-0.022871
CYR61	0.022861
ETNPPL	0.022856
RHOJ	-0.022803
PLVAP	-0.022790
PCGF3	0.022788
UAP1L1	-0.022785
NDUFC1	-0.022774
OSMR	-0.022772
TMEM204	-0.022745
UBL4A	-0.022733
ATF4	0.022669
LXN	-0.022663
SMDT1	-0.022655
KCTD12	-0.022645
ARAP3	-0.022580
NDUFS6	-0.022557
NDUFB3	-0.022550
NR1I3	0.022528
SLC44A3	-0.022524
NUDT18	-0.022496
GNAI2	-0.022451
TAT	0.022404
SEPW1	-0.022386
MAGED2	-0.022370
MARCO	0.022267
TTC39A	-0.022190
CDC42EP3	-0.022179
CHST2	-0.022125
RPS26	-0.022098
GRTP1	0.022062
HPS4	0.022044
SYT1	0.022040
MRPS21	-0.022031
RASIP1	-0.022008
RCAN2	-0.022004
TF	0.021986
HIST1H2AA	-0.021966
SEPT8	-0.021910
RPS19	-0.021887
HIST4H4	-0.021879
OR2A12	0.021866
KLHL2	0.021829
SMIM12	-0.021754
LGR5	0.021677
ENG	-0.021669
CDHR5	0.021668
APOH	0.021664
EVA1A	0.021651
LIMK1	-0.021636
PTPN18	-0.021632
FGG	0.021630
SPPL2B	0.021547
IFRD1	0.021524
LEP	0.021524
GUCA1A	-0.021500
UGT2B7	0.021481
CLIC1	-0.021460
CYP51A1	0.021408
NDUFB7	-0.021397
TGFBI	-0.021374
CCNL1	0.021343
ATPIF1	-0.021332
TGM2	-0.021312
HMGCS2	0.021303
BCAR3	0.021291
ANXA3	-0.021285
PPAP2B	0.021285
GPC3	-0.021276
PRMT2	-0.021255
FKBP9	-0.021164
ACSL1	0.021164
KLF7	-0.021157
SCAND1	-0.021140
TIMM8B	-0.021112
CIDEA	-0.021093
NCKAP1L	-0.021091
DRAP1	-0.021063
MRPS16	-0.021039
TMEM2	-0.021034
ELTD1	-0.021030
FGA	0.020973
NFIL3	0.020956
COL14A1	-0.020922
SH3BGRL3	-0.020910
EGFR	0.020893
KRTCAP2	-0.020892
COL6A1	-0.020887
PER3	-0.020877
SEPHS2	0.020871
COX7A2	-0.020870
PECAM1	-0.020866
MRPL34	-0.020855
SP5	0.020836
LTBP4	-0.020805
P2RY6	-0.020796
GNA12	0.020734
LRIT1	0.020727
CNIH4	-0.020716
ATP5L	-0.020652
ADRB2	-0.020610
SPATA24	-0.020598
LSM3	-0.020597
COL1A1	-0.020595
LAMC1	-0.020565
SNCA	-0.020544
CPS1	0.020513
ADH4	0.020504
OBP2B	0.020466
DCAF11	0.020456
THBS2	-0.020443
SNRPD2	-0.020436
SOD3	-0.020418
ZC2HC1A	-0.020403
ACSM1	0.020389
IL16	-0.020389
POLR2F	-0.020387
RPP38	-0.020376
GNG10	-0.020376
CDC42EP5	-0.020375
COX14	-0.020366
MAP4K4	-0.020345
ABCG8	0.020344
PROX1	0.020311
ALOX5AP	-0.020283
PLEKHA2	-0.020234
CYP7A1	0.020172
TREM2	-0.020167
SLC25A44	-0.020117
NPM3	-0.020114
TMEM141	-0.020089
SCAP	0.020045
ARHGAP26	-0.020042
TNFRSF21	-0.020029
TIMM10	-0.020015
FTH1	0.020002
SORD	0.019997
DCBLD1	-0.019989
WLS	-0.019988
OSGIN1	0.019966
TIMM10B	-0.019951
GALE	-0.019922
RBMS3	-0.019870
NAT8B	0.019839
EPB41L2	-0.019825
RRAS	-0.019817
SLCO1B3	0.019804
AQP9	0.019804
UBL5	-0.019795
TMEM30A	0.019786
CCL24	-0.019760
COLEC10	-0.019756
BOLA3	-0.019725
NOX4	0.019724
MSN	-0.019718
TARS	0.019713
ERMP1	-0.019692
LY86	-0.019684
SLC51B	-0.019675
FKBP5	-0.019660
SDC3	-0.019656
FAM149A	0.019644
MRPL52	-0.019641
ATP5G2	-0.019635
EDNRA	-0.019629
NMRK1	-0.019620
SEPN1	-0.019616
UQCC2	-0.019596
FCGRT	0.019582
APOA2	0.019579
C9	0.019575
C14orf2	-0.019565
CBR3	-0.019547
MYL7	-0.019530
ROMO1	-0.019523
NUPR1	-0.019508
UXT	-0.019491
APOE	0.019490
RPL35	-0.019488
GPR97	-0.019469
GIMAP6	-0.019467
DBT	0.019466
CHURC1	-0.019462
LAMTOR4	-0.019448
AQP4	0.019427
S100A1	-0.019421
GATA2	-0.019410
AXL	-0.019384