!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Cobalt dichloride hexahydrate
!smiles	O.O.O.O.O.O.[Cl-].[Cl-].[Co+2]
!pubchem_cid	24643
!cell_type	MH1C1 liver cell line - 310 uM
!organism	rat
!end_metadata
ABCG8	-0.069307
CYP1A2	-0.068059
COL9A1	-0.066250
C5	-0.066217
HMOX1	0.064568
TFF3	-0.063647
ZFAND2A	0.063479
MAFF	0.061875
HMGCS2	-0.061673
AQP8	-0.061078
PIK3C2G	-0.059556
FAM102B	-0.059239
HPD	-0.058060
SERPINA10	-0.057259
SLC38A4	-0.056934
DYNC2LI1	-0.056609
MIA	-0.056179
SLC2A2	-0.055932
CALML4	-0.055640
FGA	-0.055563
CYP1A1	-0.053537
IGFBP6	0.053522
PTPRM	-0.053116
PAH	-0.052260
DDIT3	0.050637
FILIP1L	-0.050338
RGN	-0.049325
GPR88	-0.048246
TENM3	-0.047948
NRP1	-0.047910
LMCD1	-0.047619
SNX10	0.047594
DMRT1	-0.047206
HP	-0.046955
SLC7A11	0.046882
HACL1	-0.046442
SLC2A1	0.045675
PROC	-0.045158
DEDD2	0.045106
MYLK	-0.045037
CXCL10	0.044552
KRT36	-0.044490
KCNE4	0.044125
ATF3	0.043968
CREG1	0.043885
VTN	-0.043814
C9	-0.043580
PLG	-0.043172
GDF15	0.043094
GAMT	-0.042326
MAN2A1	0.041638
ALDOB	-0.041494
ERO1L	0.041317
B4GALNT1	-0.041305
GCLC	0.040535
KNG1	-0.040182
APCS	-0.040125
ADAMTS1	0.040017
CPEB1	0.039973
DDC	-0.039960
TRIB3	0.039833
FMO3	-0.039713
ADAMTS4	-0.039607
UBE2O	0.039582
TGM2	-0.039410
PRELP	-0.039307
ELOVL6	-0.039244
CELSR1	-0.038950
CDH17	-0.038670
GADD45A	0.038550
PRR15L	-0.038518
HIGD1A	0.038508
DAPL1	-0.038480
CDKN3	-0.038267
RUSC2	0.038157
DIXDC1	-0.038086
RNASE1	-0.037772
IFRD1	0.037535
C8A	-0.037485
SERPINB9	-0.037287
CTDP1	0.037048
RHPN1	-0.036902
CRP	-0.036883
CCNB2	-0.036794
ITIH3	-0.036731
ANKS4B	-0.036620
TRPM3	-0.035834
MOCOS	0.035651
CCNB1	-0.035478
AHSG	-0.035234
GCKR	-0.035085
CIDEC	-0.035008
ITIH4	-0.034882
ALDH1A1	0.034850
CHPF2	0.034812
CLDN2	-0.034753
FXYD3	-0.034665
P4HA1	0.034551
AFMID	-0.034428
CASP4	0.034408
TGFB3	-0.034405
SPP2	-0.034264
EPB41	0.033940
SLC7A7	-0.033811
ANGPTL4	-0.033720
FUT4	-0.033602
EHF	-0.033580
PPP1R15A	0.033561
HSPB8	0.033516
DYNC1I1	-0.033508
SLC25A21	-0.033407
ZBTB7B	0.033399
ABHD2	0.033181
LRP2	-0.033098
BNIP3	0.033056
PHYHD1	-0.032903
SEMA6A	0.032902
WDR5B	-0.032769
RASL11B	-0.032609
ALDH3A1	0.032553
INHBB	-0.032523
ATP1A2	-0.032456
PON3	-0.032254
CSPG5	-0.032192
SPTA1	0.032153
NFE2	-0.031901
MYZAP	-0.031863
NEDD9	-0.031764
NAT8	-0.031760
RASSF4	-0.031603
TRIM2	-0.031601
OSER1	0.031573
SH3TC1	0.031564
PTGR1	0.031548
PTTG1	-0.031495
CPPED1	-0.031274
FBXO30	0.031256
BARD1	0.031064
TNFRSF9	-0.031037
VCAN	-0.031028
CHDH	-0.030994
LPCAT1	-0.030950
PDZK1IP1	-0.030946
HRSP12	-0.030879
ITIH1	-0.030825
WIF1	-0.030805
AK4	0.030791
GNAT3	0.030614
DNASE1L3	-0.030610
MLLT11	0.030537
ZNF416	0.030532
CDC42EP5	-0.030506
PYGL	0.030414
RAP1GAP	-0.030406
CNDP1	-0.030371
ABCA4	0.030273
PBX3	-0.030252
SLC13A4	-0.030218
PSMB3	0.030188
ENTPD5	0.030163
CPB2	-0.030096
PDE11A	-0.030065
CROT	-0.030039
FAM129A	-0.029921
AQP5	-0.029919
GSR	0.029873
PIR	0.029867
NAPB	0.029847
AIM1L	-0.029835
KDM3A	0.029834
TRPS1	-0.029814
LTBP1	-0.029772
MAP2K3	0.029650
MARCH3	0.029607
HGFAC	-0.029514
BHLHE40	0.029387
SLC6A9	0.029376
TACC2	0.029362
DNAJB1	0.029122
TCP11L2	0.029121
AGXT2	-0.029116
AZGP1	-0.029033
LECT2	-0.029019
PPP1R1B	-0.028962
POSTN	-0.028827
PELO	0.028814
SLC17A3	0.028756
GCLM	0.028588
BACH1	0.028556
SUOX	-0.028547
MBOAT1	-0.028496
ARL11	0.028308
HSD17B7	-0.028269
HTRA1	-0.028227
GRB14	-0.028208
SLC30A1	0.028203
ABCG5	-0.028171
PLCL1	-0.028041
NAMPT	0.028018
KLF5	0.027946
P2RY2	0.027865
SCCPDH	0.027789
FGGY	-0.027773
TCEAL5	-0.027706
ZNF773	0.027665
GCH1	0.027664
ANKRD37	0.027637
RTN1	0.027605
PCCA	-0.027596
CFB	-0.027583
THADA	-0.027530
CTSD	0.027491
OLFML3	-0.027471
MYCN	-0.027430
DACT1	-0.027386
MATN3	-0.027356
PHYH	-0.027220
MYH14	-0.027218
OSTF1	0.027156
GPX1	-0.027107
ABHD5	0.027040
TRIM16	0.026961
ASPRV1	-0.026794
RASSF3	-0.026784
ANXA4	-0.026650
ILDR2	-0.026604
IRAK2	-0.026523
SLC25A33	0.026309
ACVR2A	0.026250
MSI2	-0.026218
FAM89A	-0.026199
MBIP	-0.026079
PSCA	-0.026066
ATG14	0.026059
SLC17A1	0.026045
TLE6	-0.025898
LRP4	-0.025880
SLC22A17	-0.025767
UBE2C	-0.025752
CHN2	-0.025718
TXNRD1	0.025709
SLC50A1	-0.025707
RWDD2A	-0.025695
PDK1	0.025485
CELA1	-0.025479
BPHL	-0.025396
SLC48A1	0.025225
NOTCH1	-0.025225
MAFK	0.025179
ZXDC	0.025167
MYRF	-0.025120
AFG3L2	0.025105
FMO2	-0.025102
F5	-0.025049
LIN54	0.025038
OSBPL2	0.025019
SLC3A2	0.024993
SBSN	-0.024980
ZNF367	0.024971
CAPN6	-0.024959
GSTA3	0.024891
LIPC	-0.024889
CHKA	0.024879
SRXN1	0.024852
SMIM22	-0.024849
CREB3	0.024717
ARHGEF2	0.024676
PDGFA	-0.024673
TTR	-0.024646
PRND	-0.024613
DNAJB9	0.024583
IQUB	0.024554
GALNT4	-0.024548
FNIP1	0.024491
UCP2	-0.024465
PORCN	-0.024459
CENPW	-0.024450
NIT2	-0.024450
DUSP5	0.024419
SLC28A2	-0.024378
TEX10	0.024376
KIF12	-0.024374
NPLOC4	0.024365
IFITM3	-0.024337
APOA5	-0.024317
KIAA1217	-0.024299
RNASEL	-0.024219
ONECUT2	-0.024144
LY96	0.024131
CHORDC1	0.024129
GNG3	-0.024123
STK40	0.024116
NEIL1	-0.024107
TATDN2	0.024089
AP1S2	0.024089
LYRM5	-0.024073
GJB1	-0.024068
DDIT4	0.024043
HAP1	0.024035
CASQ1	-0.024019
CCDC125	-0.023967
ABCB6	0.023952
OTUD4	0.023919
SIAH2	0.023907
GPSM2	-0.023854
RTP4	-0.023853
USP14	0.023849
PPAP2B	-0.023838
C2CD5	-0.023809
UBXN2A	0.023807
POLD4	-0.023769
ABCC4	0.023764
PSMD3	0.023758
TCF4	-0.023750
RCAN2	0.023748
ELL	0.023582
CRYBA4	-0.023578
PLCE1	-0.023576
RSPH1	-0.023574
MORN5	-0.023477
CBR4	-0.023450
KIFAP3	-0.023441
DYNC1H1	0.023392
RLF	0.023389
GPR107	0.023286
ANPEP	-0.023264
WHAMM	0.023263
CDR2	0.023218
HPSE	0.023211
UNC5CL	-0.023181
FAM107A	-0.023114
BTD	-0.023104
NUDT14	-0.023080
PLCB1	-0.023072
GYS1	0.023065
CAV2	-0.023056
BAG2	0.023047
PALMD	-0.022999
CITED1	0.022990
PKDCC	-0.022935
H1F0	-0.022913
FAM110B	0.022886
ITGB6	-0.022856
OSGIN1	0.022802
PAPSS1	-0.022799
DGKA	-0.022799
PTS	-0.022778
SLC6A6	-0.022746
PKMYT1	0.022734
COL13A1	-0.022675
BSCL2	-0.022670
TMEM57	0.022647
ABHD10	0.022600
PAK1	-0.022596
EDRF1	0.022584
GOLT1A	-0.022575
TMCC3	-0.022573
INSIG2	0.022557
AKR1B10	0.022551
WFDC2	-0.022541
TPMT	-0.022526
INMT	-0.022509
VWC2	-0.022483
SRBD1	-0.022476
MMP7	-0.022476
CEP152	0.022469
PFKL	0.022459
UFD1L	0.022457
BCKDK	-0.022456
SH3BP2	0.022432
PPP1R36	-0.022414
GBE1	0.022399
CA9	0.022369
GAL3ST1	-0.022359
RAB40B	0.022328
SERPINA6	-0.022260
PDLIM2	-0.022254
LPAR6	-0.022219
EDEM2	-0.022219
VEGFA	0.022206
HIST2H3A	0.022205
PSMD5	0.022195
STEAP1	0.022179
RSAD2	0.022153
TRAK2	-0.022152
B4GALT6	-0.022127
MAPK15	-0.022075
PGM2	0.022052
CGRRF1	0.021959
SLC22A4	0.021923
TIFA	-0.021903
ABLIM3	-0.021897
ADTRP	-0.021877
SLC22A1	-0.021815
RAB11FIP5	0.021810
ONECUT1	-0.021791
CENPE	-0.021775
ADRM1	0.021737
SHPK	0.021728
STBD1	0.021683
NABP1	0.021645
CDC14A	-0.021600
PCOLCE2	-0.021594
ATMIN	0.021589
CLIC5	-0.021567
DECR1	-0.021549
FASN	-0.021526
MYOF	-0.021494
TGFB2	-0.021492
SPA17	-0.021472
FURIN	-0.021464
CHD3	-0.021446
SH3BP5	-0.021435
SLC15A4	0.021433
DDAH1	-0.021415
SLC29A1	-0.021404
BRD7	-0.021393
LRRK1	-0.021381
CNKSR1	0.021381
WBP1	-0.021375
TSPAN17	0.021348
FGF1	-0.021307
FJX1	-0.021288
KDSR	-0.021277
UCMA	-0.021260
INHBE	0.021242
PSMD12	0.021231
SLC1A2	-0.021230
GYS2	-0.021221
FMO5	-0.021183
PSMD1	0.021180
RIOK3	0.021175
ACYP2	0.021174
KRT19	-0.021159
ZFYVE1	0.021149
SDR39U1	-0.021128
N4BP2L1	0.021124
SLC35D2	-0.021116
ACO1	-0.021112
TGFBI	-0.021111
NGEF	-0.021091
KNSTRN	-0.021089
SCPEP1	0.021080
HCFC2	0.020965
GNB1L	0.020932
CP	-0.020854
RTN4R	0.020813
STC1	0.020807
MYBL2	0.020763
PGC	-0.020756
NOL3	0.020737
MAGIX	-0.020733
NAT2	-0.020698
IRX2	0.020691
EEPD1	0.020675
ETFB	-0.020667
SOD3	-0.020665
PLS1	-0.020661
L3MBTL3	-0.020648
ARMC10	-0.020634
CDS1	-0.020605
RAD51AP1	0.020593
FMN1	0.020593
PSMD4	0.020551
DUSP23	-0.020538
NFKBIA	0.020535
P2RX4	-0.020510
SYNE4	-0.020505
PARPBP	-0.020503
IL18	-0.020466
CRYZ	-0.020465
SNX7	0.020462
EML4	-0.020458
SLC15A2	-0.020458
TLR4	0.020443
TNFRSF19	-0.020442
ZNF354A	0.020438
FDXACB1	-0.020437
PRELID2	0.020410
CELF5	-0.020408
APLN	0.020406
AGMAT	-0.020401
ME1	0.020385
USP33	0.020371
RHOBTB3	-0.020359
ARG1	-0.020356
HINFP	0.020353
CFH	-0.020338
PDE8A	-0.020277
TIMM17B	-0.020263
ANGPTL3	-0.020243
ZNF629	0.020243
MMACHC	-0.020239
KIAA1715	0.020238
RUFY1	-0.020235
ALDOA	0.020226
LIMD2	-0.020199
CDT1	0.020172
STARD13	-0.020164
MPND	-0.020145