!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!old	72-79
!young	61-67
!cell_type	CD4+Tlyphocytes
!age_unit	year
!organism	human
!end_metadata
NKG7	0.074704
GZMH	0.073102
HLA-DRB5	0.069507
GNLY	0.059474
EOMES	0.057598
MYOM2	0.057103
FAM13A	-0.056109
GNLY	0.055861
TARP	0.055854
FGFBP2	0.054224
FAM13A	-0.050974
THBS1	-0.049954
HES4	-0.049284
S1PR5	0.049171
SPATA13	-0.047721
GPR56	0.046635
GZMA	0.046406
IL18RAP	0.046245
KRT72	0.046024
CX3CR1	0.045814
VAV3	0.045533
SLC7A5	-0.045373
IER3	-0.044755
CRIP2	-0.042606
SIK1	-0.042429
GPR56	0.041121
PRF1	0.039015
CLK1	-0.038014
PLAUR	-0.037849
CDKN1A	-0.037679
PTPRC	-0.037321
GZMB	0.037011
SLC39A8	-0.036799
DDIT3	-0.036470
KLRD1	0.036399
CST7	0.035361
BCLAF1	-0.035121
CCL5	0.035020
GZMK	0.034824
GSTM1	0.034695
IL1B	-0.034659
ZNF331	-0.033850
ZNF331	-0.033743
PTPRC	-0.033719
FOXP1	-0.033656
NCAPG2	-0.033575
CTAG2	0.033507
KLRD1	0.033188
FAM118A	-0.033089
RORA	-0.033050
FBXW7	-0.032851
PROK2	0.032786
CMTM8	-0.032716
CCL5	0.032456
CREBBP	-0.032209
SLC2A14	-0.032069
NEU4	-0.031712
ATF3	-0.031598
IDI1	-0.031102
MAFB	-0.030933
SRI	-0.030693
SDHAP1	-0.030421
CHN1	0.029989
NR4A2	-0.029559
SRI	-0.029474
KRT73	0.029415
SNHG15	-0.029281
NR4A3	-0.029028
RRAGD	-0.028986
SLC40A1	-0.028931
TTC38	0.028927
CCL3L3	-0.028862
PPFIBP2	-0.028760
CLEC7A	-0.028751
AAK1	-0.028735
OSBPL8	-0.028667
WDR33	-0.028624
NFS1	0.028531
CXCL2	-0.028208
ZNF791	-0.028174
RORA	-0.028122
FAM43A	-0.028090
GABARAPL1	-0.027969
SMAD7	-0.027965
RPS26	0.027936
XAF1	0.027806
GADD45B	-0.027622
MAP1LC3A	-0.027529
NAPSB	-0.027261
MYADM	-0.027226
RNF125	-0.027214
BIRC3	-0.027058
MDGA1	0.026981
MYADM	-0.026922
SC5D	-0.026805
RPS4Y1	0.026693
ARRDC2	-0.026673
CXorf38	-0.026511
FAM170B	0.026506
AVPI1	-0.026444
PASK	-0.026389
TSPAN18	-0.026361
PRSS23	0.026359
DBH	-0.026226
PRMT2	-0.026219
RPS26P11	0.026064
GPCPD1	-0.026039
LGALS2	-0.026036
GRASP	-0.025835
NELL2	-0.025827
HIST1H2BK	-0.025757
HOPX	0.025716
COL4A3BP	-0.025702
NR4A2	-0.025693
NAAA	-0.025672
SLC15A4	0.025618
ZNF815P	-0.025600
ETV3	-0.025586
SF1	-0.025573
INSIG1	-0.025551
IL16	-0.025541
CCL3L1	-0.025488
KLRG1	0.025413
GRB2	-0.025315
CCL3L1	-0.025279
PAG1	-0.025199
MAFF	-0.025053
FAM13A	-0.024885
PTS	-0.024820
CXCL8	-0.024796
NAAA	-0.024796
RAB30	-0.024793
PRKAR1A	0.024772
MIDN	-0.024685
SGK1	-0.024624
PLK3	-0.024541
RGCC	-0.024518
CCL3L1	-0.024509
YTHDC1	-0.024489
JOSD1	-0.024389
FAM105A	-0.024361
TMEM176A	-0.024330
TIMM10	0.024306
RYBP	-0.024279
CENPK	0.024258
SERPINE2	0.024141
NAAA	-0.024095
ADAM7	0.024060
ATP13A1	0.023934
D2HGDH	0.023930
ARID4B	-0.023880
KDM5D	0.023858
DGCR8	0.023761
PASK	-0.023633
EMP1	-0.023613
LAIR2	0.023552
MCEMP1	-0.023282
OLR1	-0.023246
IRS2	-0.023225
HLA-DQB1	-0.023207
SESN3	-0.023194
SH3KBP1	-0.023160
DUSP6	-0.023149
PFKFB3	-0.023098
TSPAN32	0.023073
LMNA	-0.023034
COL18A1	0.023030
GBP5	0.022891
ARL4A	-0.022839
RPS4Y2	0.022839
ADM	-0.022823
TOB1	-0.022801
GSTM4	0.022633
G0S2	-0.022617
CD93	-0.022593
FBXO32	0.022558
PLEK	0.022534
SELK	-0.022517
IPO8	-0.022452
ELF2	-0.022349
BCOR	-0.022346
CXCL16	-0.022327
NHP2L1	-0.022316
SAMD3	0.022302
KAT2B	-0.022260
AZIN1	-0.022239
ICA1	0.022202
RRP12	-0.022198
ZNF502	-0.022135
BTG2	-0.022081
SBDSP1	-0.022069
PVRL3	-0.022065
FCGBP	-0.022018
MATR3	-0.022017
SBDSP1	-0.021964
SNN	-0.021916
CD83	-0.021895
TMEM176B	-0.021868
WDR33	-0.021840
RPL22L1	-0.021819
LAPTM4B	-0.021816
NRIP3	-0.021703
HIF1A	-0.021518
DUSP8	-0.021489
QPCT	-0.021468
GSTM3	-0.021455
N4BP2L2	0.021423
ENC1	0.021402
NBPF14	-0.021381
SEC14L2	-0.021338
GRINA	-0.021208
RAB33A	-0.021207
PLEKHG3	0.021189
KANK1	-0.021055
WHAMM	-0.021052
XIST	-0.021013
HIST1H1C	-0.020984
CCR1	-0.020927
GPATCH4	0.020924
MRPL52	0.020887
PNP	-0.020858
HKDC1	0.020850
RBM38	-0.020839
SGK223	0.020833
SPI1	-0.020827
SDHAP1	-0.020782
CHD2	-0.020766
HAVCR2	-0.020741
TSGA10	-0.020663
GPR114	0.020649
MKKS	0.020641
ANKRD9	-0.020597
RPS23	0.020540
STOM	0.020503
RHOC	0.020420
RBM38	-0.020382
TAGAP	-0.020365
IL32	0.020297
HIF1A	-0.020275
OR1N1	-0.020264
GAB2	-0.020231
GADD45A	-0.020184
ELK4	-0.020144
CWC25	-0.020129
GADD45A	-0.020128
HBEGF	-0.020116
KAT6B	-0.020106
GLRX	0.020092
BSG	0.020090
BIRC2	-0.020089
NAMPT	-0.020084
SPTY2D1	-0.020068
BIRC2	-0.020055
SEPT5	0.020051
HLA-DRB4	-0.020045
HLA-A	-0.020011
COL5A3	0.019937
DDX11	-0.019932
EFHD2	0.019913
PIK3R1	-0.019904
WDR33	-0.019862
SMAD7	-0.019850
ELL2	-0.019838
CTH	-0.019828
LOC100419583	0.019793
RBM39	-0.019759
ZRANB1	-0.019742
TMEM158	-0.019643
IFI44L	-0.019643
HIST1H4B	0.019617
SAMD3	0.019604
TTC38	0.019528
APOBEC3F	0.019519
TPM2	-0.019511
SGK3	-0.019502
LYAR	0.019493
PCMT1	0.019490
DBNDD1	0.019459
PRDM1	0.019458
GPR132	-0.019364
SYNE2	0.019360
CD83	-0.019354
BEND4	0.019339
N4BP2	-0.019328
STAT1	0.019286
LEPROT	-0.019268
OSBPL5	0.019262
PAPD5	-0.019260
VPS37B	-0.019211
NAMPT	-0.019120
CTSG	0.019058
ARL4A	-0.019047
UNC45A	0.019009
PEX11B	0.018978
VAV1	0.018977
WTAP	-0.018975
RGS16	-0.018941
MMP9	-0.018939
CXCR5	-0.018935
PCSK1N	-0.018867
CXCR5	-0.018862
USP3	-0.018846
BATF	0.018844
TGFBRAP1	-0.018837
MEGF9	0.018832
MCOLN2	0.018813
CCL3	-0.018786
IL6ST	-0.018734
SPATA20	0.018704
FHOD1	0.018661
SP100	-0.018650
CSNK1D	-0.018626
JMY	-0.018610
C9orf72	-0.018590
CD55	-0.018588
KCNRG	-0.018566
DACT1	-0.018565
ZHX2	0.018546
TNPO1	-0.018537
GIMAP4	0.018517
SLC11A1	-0.018399
SNORD14C	-0.018364
ID3	-0.018340
ST3GAL5	-0.018309
ARL4A	-0.018302
ZNF181	0.018274
SPATA2L	-0.018263
SP6	-0.018251
EXOC3L1	-0.018232
LAPTM4B	-0.018207
SOCS3	-0.018195
DHRS3	-0.018145
FAM49A	-0.018123
YPEL5	-0.018113
VPS13C	-0.018082
RARA	-0.018063
DUSP4	-0.018042
CLEC12A	0.018023
GOLGA8A	-0.018020
EEF1G	0.018008
ORAI1	0.018007
NFIL3	-0.017965
GPR183	-0.017961
LILRA3	-0.017940
CNTNAP1	-0.017896
FOSB	-0.017891
SEC14L1	-0.017888
PLAUR	-0.017886
NUPL2	0.017882
HCP5	0.017837
LAIR2	0.017814
LYPD3	-0.017800
SLC2A3	-0.017798
E2F2	0.017791
CEP85L	-0.017732
SPAG1	0.017715
TNFSF10	0.017715
STOM	0.017658
MATK	0.017641
TXNIP	0.017618
DCUN1D1	-0.017589
STAT1	0.017586
AUTS2	-0.017584
ZNF185	-0.017563
FAM207A	-0.017535
SAP30	0.017527
KDM6A	-0.017499
MNT	-0.017466
ZFP91	-0.017465
DHX32	0.017453
UBQLN1	-0.017451
USP10	-0.017404
DPYSL4	0.017395
ARPC5	0.017391
CHI3L2	0.017390
ALG13	-0.017376
GALR2	-0.017368
COTL1	-0.017360
GPRIN3	-0.017360
ILDR1	-0.017346
ID1	-0.017326
PPP1R15A	-0.017311
OSM	-0.017296
LMNA	-0.017289
UGGT1	-0.017248
MTFP1	-0.017246
TBC1D15	-0.017246
SOCS3	-0.017204
FBLN7	-0.017167
CCNH	-0.017142
PPP2R2B	0.017138
OCIAD2	-0.017131
RNF19A	-0.017119
PGS1	0.017114
MTURN	-0.017102
SMIM7	0.017087
AHCTF1	-0.017063
MBNL3	-0.017048
NFAT5	-0.017047
KCNT1	0.017045
NAPSA	-0.017037
PEX6	-0.017031
ATP2C1	-0.017019
DCAF4	-0.017012
NPSR1	0.016993
FAM174A	-0.016991
UBXN2A	-0.016990
INSIG1	-0.016964
RNF31	0.016940
GSTM1	0.016913
DNAJB6	-0.016912
LOC93622	0.016890
MTFP1	-0.016886
OPN1SW	-0.016854
SIAH1	-0.016841
TAOK1	-0.016825
DPY30	0.016818
HPS6	0.016815
DACT1	-0.016811
HK2	-0.016795
SDCBP	-0.016780
GBP1	0.016746
TRIB1	-0.016720
OR2A5	-0.016717
FOSL2	-0.016717
RAB10	0.016712
ITPRIP	-0.016657
PIK3CA	-0.016654
SH2D3C	0.016633
MTMR6	-0.016610
CLDN18	-0.016600
LOC101928370	-0.016596
PYHIN1	0.016535
IRF2BP2	-0.016516
KIR2DL1	0.016483
METTL21B	0.016476
DPYSL2	0.016459
IL6R	-0.016445
UBAP2L	0.016443
ARG1	-0.016438
BCL6B	-0.016417
GTF2I	0.016403
RORA	-0.016394
FZD6	0.016386
ABCA1	-0.016377
FTH1	-0.016376
HIST1H4A	-0.016367
P2RY8	-0.016354
AQP9	-0.016346
IRF2BPL	-0.016314
PTPN12	0.016305
DNAJB6	0.016281
ARID5A	-0.016275
PLAUR	-0.016268
PSMG1	0.016264
CROCCP3	-0.016264
PTGS2	-0.016262
HMOX1	-0.016259
UBE2E2	-0.016248
LDLRAP1	0.016245
ADRB2	0.016232
APOBEC3F	0.016177
UBE2D2	-0.016175
CCNH	-0.016169
CD300A	0.016155
S100P	-0.016150
NAA16	0.016144
LACTB2	0.016131
UBASH3A	0.016126
QKI	-0.016123
TMEM2	-0.016108
ZFP1	0.016107
MCPH1	0.016102
PIK3R6	-0.016084
UBE2H	-0.016076
PRKACB	-0.016048
MUC1	0.016042
AKAP7	-0.016041
RCL1	-0.016036
TRAF3IP3	0.016035
MAN1C1	-0.016009
TMEM107	0.015996
CCDC167	0.015986
SOCS1	-0.015984
ICA1	0.015977
ARHGEF10	0.015973
CUL5	0.015914
SARS	0.015907
WDR86	0.015903
SLC43A2	-0.015901
SNX24	0.015892
RAB38	0.015890
RGS1	-0.015889
RFC4	0.015880
CD58	0.015874
WDSUB1	0.015867
MRPS31	0.015858
GFI1	0.015846
RGPD5	-0.015844
VEGFA	-0.015841