!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Doxycycline
!smiles	CC1C2C(C3C(C(=O)C(=C(N)O)C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)N(C)C)O
!drugbank_id	DB00254
!pubchem_cid	5281011
!cell_type	Embryoid bodies -  48 Hours
!organism	mouse
!end_metadata
TRH	-0.176886
PHLDA2	0.168216
HPRT1	0.166313
IGF2	0.158595
DNMT3B	-0.146949
SLC2A1	-0.133937
ID1	0.129054
PIM2	-0.127779
CDH1	-0.122465
OTX2	-0.118769
S100A10	0.113671
UPP1	-0.112799
ERAS	-0.111333
MTM1	-0.109614
SOX2	-0.109561
FN1	0.107486
IGFBP2	-0.105738
CHCHD10	-0.105050
G3BP2	-0.104550
VIM	0.103959
ASNS	0.098480
F2R	0.092935
PHC1	-0.086878
CDH11	0.086753
POU5F1	-0.082782
ASB4	0.080618
CTBP2	-0.080604
MESP1	0.080433
PSAT1	0.080093
PMP22	0.079443
CYP26A1	0.076868
SLC2A3	-0.071429
NME1	0.070474
FAM60A	-0.070367
RPL26	0.069189
SPP1	-0.069102
SMAD1	0.068767
RBPMS2	-0.068261
PKM	-0.067122
EMB	-0.065571
PPIC	0.064573
ACAT2	0.064488
RPL28	0.064463
LDHB	-0.064194
APLNR	0.063824
DPPA5	0.063266
SLC7A3	-0.060908
PPIB	0.059358
RPS5	0.058507
HSP90AA1	-0.058194
DPYSL2	0.056408
GPC3	0.056062
FOXA2	-0.055780
MKRN1	-0.055729
SET	-0.055609
ID3	0.055558
RPLP2	0.055487
PLS3	-0.054821
FSTL1	0.054319
RPL13	0.054160
BASP1	0.053328
FTL	-0.052711
CDH2	0.052626
RPS29	0.052504
KDR	0.050031
FAU	0.049848
FST	-0.049713
TCFL5	-0.049677
BNIP3	-0.049538
DLL3	0.049420
USMG5	0.048966
SYCP3	-0.048772
RPS24	0.048736
RPS23	0.048702
SYCE2	-0.048603
SLC25A4	0.048564
EPCAM	-0.048380
SLC38A4	0.048104
SLC7A5	0.047818
CLDN7	-0.047817
APOE	-0.047681
RBP1	0.047307
RPS2	0.047018
ZIC2	-0.046758
RPL13A	0.046723
ABCC4	-0.046571
AKAP12	-0.045720
RPLP0	0.045677
NDUFA1	0.045531
SPINT2	-0.045345
ZIC5	-0.045195
RBMS1	0.044873
FGF5	-0.044465
TUBA1B	0.043987
SLC27A2	-0.043568
FEM1B	-0.043411
NPM1	-0.043409
MSX1	0.043322
MSH6	-0.043280
PHLDA1	0.042321
MYADM	0.042232
TPI1	-0.042151
LAPTM4B	0.042096
PITX2	0.041974
CCNG1	0.041888
CA4	-0.041820
AHCY	-0.041735
RPS27A	0.041488
LBR	0.041389
PRTG	0.040351
NME2	0.040097
TCEAL8	0.040059
NANOG	-0.040057
RPL11	0.039785
MUM1L1	0.039679
RPS15	0.039476
EEF1B2	0.039264
KPNA2	-0.039132
PCNA	-0.039124
TUBA4A	-0.039109
PAICS	-0.038948
MIXL1	0.038947
TMEM88	0.038610
BMP4	0.038600
FTH1	0.038286
ATP5B	-0.038204
NAF1	-0.038158
IGFBP4	0.037922
PDCD4	-0.037918
KRT18	-0.037027
RNF145	-0.036979
SNRPB	-0.036951
RPL7	0.036796
PEG3	0.036691
UGDH	0.036532
CYB5A	0.036324
TAGLN	0.036229
GPI	-0.035942
RPS28	0.035900
TMEM185A	0.035736
RPS19	0.035625
PAIP2	-0.035352
AJUBA	-0.035205
RPS27L	0.035061
RPSA	0.034935
BSG	-0.034837
RPL23	0.034701
EIF4A1	-0.034560
RRM2	0.034316
ABRACL	0.034311
CITED2	0.034260
VBP1	-0.034178
TGIF1	-0.034056
BEX4	-0.033925
GARS	0.033766
ACKR3	0.033663
GLDC	-0.033181
HAX1	0.032788
BEND3	-0.032652
TDGF1	-0.031564
HEXA	-0.031493
PHGDH	0.031254
DDT	-0.031136
CLDN6	-0.031113
SLC16A1	-0.030826
RPL14	0.030701
GPX4	-0.030616
BMP2	0.030589
CNKSR3	-0.030521
ETV2	0.030493
MAGED1	0.030479
TRIM28	-0.030341
PTPLA	0.030217
SMAD6	0.029983
CSTB	-0.029950
ATP6V1F	-0.029724
RPL3	0.029514
KDELR2	0.029422
GJA1	-0.029385
RPS14	0.029369
HN1	-0.029288
EVX1	0.029238
DEGS1	-0.029229
SOCS2	-0.029145
SERPINH1	0.029137
ARL4C	-0.029124
CRABP1	0.029092
MRFAP1	0.029062
IARS	0.028878
CDKN1A	0.028647
UBE2C	-0.028489
MAGOH	0.028482
CRIP1	-0.028410
SFXN1	0.028389
NRP1	0.028243
RPL18A	0.028099
CTH	0.027677
EI24	0.027628
IGFBP3	0.027615
NHP2	-0.027573
CBR1	-0.027533
PGAM1	-0.027463
ATP6V0D1	-0.027374
RFTN1	0.027293
DHCR7	0.027084
LEFTY2	0.027050
H2AFY	0.026958
EIF4EBP1	0.026947
CA2	0.026888
ACTB	0.026719
DUSP9	0.026595
NARS	0.026547
RPL9	0.026387
SKP1	-0.026334
KCNK1	-0.026255
PDK1	-0.026189
TPD52	-0.026165
FSCN1	0.026078
RPL27A	0.026075
CXCR4	0.026024
STX7	-0.025908
GAPDH	-0.025893
PABPN1	-0.025800
JARID2	-0.025770
ESRP1	-0.025738
RPL38	0.025716
PRDM6	0.025665
INSIG1	0.025654
GNAI2	-0.025640
MEX3B	0.025469
HMGCS1	0.025444
PSMD8	-0.025401
PHLDB2	0.025345
LIN28A	-0.025332
SNRPF	-0.025238
ITGA6	-0.025219
CCND2	0.025203
MTHFD2	0.025127
POLR2H	-0.024883
HADH	-0.024839
SEPP1	-0.024743
SLC39A8	-0.024736
IFITM3	0.024727
DPY30	-0.024711
GLRX5	0.024695
GLUD1	-0.024575
TOX3	-0.024540
EIF5A	-0.024537
ARL6IP1	-0.024495
TCP1	0.024448
CD81	0.024381
RPS11	0.024303
NOP58	-0.024281
AP1M2	-0.024202
PPP1CA	-0.024088
TP53INP1	0.024075
TJP2	-0.024025
GAS1	0.023965
ZMYND8	-0.023943
HINT1	0.023883
FABP3	-0.023863
HSPE1	0.023860
PPHLN1	-0.023851
POLR2I	0.023777
CTNNB1	-0.023688
NUDCD2	0.023687
SAP30L	0.023433
RPS26	0.023417
YWHAE	-0.023379
RPS17	0.023324
CDCA8	-0.023200
CKS2	-0.023165
PSMB7	-0.023127
CYCS	0.023123
RPS7	0.023076
STX3	-0.023058
SCD	0.023009
IFI30	-0.022854
SPRY2	-0.022830
EMC2	0.022827
SKIL	-0.022826
DBI	0.022799
SNX17	0.022520
IQGAP1	-0.022405
H19	0.022209
GDI2	0.022208
T	0.022187
RPL19	0.022131
COX4I1	0.022092
PHC2	0.022086
COL4A1	0.022071
MCM7	-0.022036
ID2	0.022012
PSMA7	-0.021973
MAP1LC3B	-0.021950
ACTG1	0.021944
RPL10	0.021919
NCL	-0.021792
LGALS1	0.021739
ARMC10	-0.021724
RANBP1	-0.021699
RPS4Y1	0.021695
RPS6KA6	0.021455
DEK	-0.021413
FAT1	-0.021349
VLDLR	0.021310
SFR1	-0.021298
MRPS34	-0.021269
SLC3A2	0.021234
MYC	0.021165
LAMP1	-0.021164
SLC25A3	-0.021109
TUBB6	0.020935
PSPH	0.020909
RPL27	0.020873
TXN	0.020846
NDFIP1	-0.020813
PBK	0.020775
KIAA0196	-0.020736
STARD8	0.020692
ATP6V0C	-0.020656
P4HB	0.020531
MST4	-0.020457
NIPSNAP1	-0.020407
METTL9	0.020371
SNX3	-0.020344
HAS2	0.020317
SPARC	0.020261
EIF3A	-0.020249
EZR	-0.020183
LARS	0.020091
GRN	-0.020064
USP28	-0.020022
PFN1	-0.019941
FREM2	-0.019920
HDAC6	-0.019897
MSN	0.019897
KLF9	-0.019882
CLTC	-0.019877
UBE2T	-0.019844
COMMD3	0.019793
LSM5	0.019760
MYL12B	0.019717
PABPC1	0.019705
NSFL1C	0.019674
KDELC1	0.019665
MRPS33	0.019664
GLO1	-0.019589
LEFTY1	-0.019580
RAN	0.019550
RPL5	0.019544
SBK1	-0.019523
GREB1L	0.019495
MYB	-0.019434
CNIH1	0.019305
MREG	-0.019250
FCF1	-0.019222
EIF3I	0.019190
PROM1	-0.019146
DUSP6	-0.019142
MYL12A	-0.019098
AP3S1	0.019088
TCF7L1	-0.019062
LRRC58	0.019012
FNTA	-0.018960
MARS	0.018953
NAE1	-0.018897
PGD	0.018866
PLCG2	-0.018845
PHF5A	-0.018836
RPL37A	0.018809
MEST	0.018783
WBP5	0.018735
TPRG1L	-0.018725
RPL35	0.018654
GSTM3	0.018638
EIF2S3	0.018622
PRKD1	0.018610
NPC2	0.018595
ELL2	-0.018590
KIAA1551	-0.018589
PGK1	-0.018588
HOOK1	-0.018576
COX5A	-0.018562
RPS25	0.018556
ERH	-0.018542
CHCHD2	-0.018533
BLOC1S2	0.018520
PAM16	0.018508
NDUFA13	0.018447
PTPRF	-0.018442
PBX3	0.018442
SMC4	-0.018432
FAM169A	-0.018416
PPP2R1A	-0.018376
CDCA5	-0.018303
ATP5A1	-0.018237
H2AFV	-0.018189
DDX5	-0.018174
EIF3G	-0.018174
HNRNPF	-0.018165
RPL15	0.018163
ATF1	-0.018113
QDPR	-0.017985
TDG	-0.017929
PDLIM4	0.017861
CTCF	-0.017816
VEGFC	0.017796
SHFM1	0.017794
MKI67	-0.017763
RCN2	0.017751
MOGAT2	0.017726
ACSL4	-0.017685
HIRIP3	-0.017681
SLC6A6	0.017656
VDAC2	-0.017628
MCM2	-0.017562
PSMB4	-0.017536
LOC728392	0.017524
ALDH9A1	-0.017471
JUND	-0.017470
SNRNP25	0.017437
ITM2B	-0.017436
DOCK11	0.017412
HSPA5	0.017376
BAMBI	0.017355
ARL3	0.017327
RAP1A	0.017326
DSP	0.017314
CHAC1	0.017275
HARS	0.017263
PSIP1	-0.017249
RPS10	0.017232
CLIC4	0.017192
LPHN2	-0.017150
AMOT	0.017137
RDX	0.017114
CYP51A1	0.017113
RIF1	-0.017078
HEXB	-0.017048
ARID2	-0.017006
STMN1	-0.016973
ZNF462	-0.016951
CTSZ	-0.016936
KLHL6	0.016928
LRP11	-0.016873
MARCKSL1	0.016870
LIMD2	0.016757
PTK7	0.016736
SARS	0.016705
RPS8	0.016651
HSD17B11	-0.016600
PSME1	-0.016597
KRT8	0.016552
UTP3	-0.016535
EIF5	-0.016498
NDUFV2	-0.016482
LPAR4	-0.016425
FAM213A	-0.016410
CTSV	-0.016395
CER1	-0.016351
LHFP	0.016316
GRB7	-0.016302
FOXH1	0.016283
SOX17	-0.016203
SDC4	-0.016184
SUMO2	0.016170
PNP	-0.016140
NDUFB11	0.016122
GNPDA1	-0.016070
MYL7	0.016043
ZFP42	-0.016021
CTSC	0.015971
HSP90B1	-0.015963
PSME2	-0.015957
PSME4	-0.015951
CAPN2	0.015867
ISYNA1	-0.015827
SNRPA1	0.015809
PRDX6	0.015765
PENK	-0.015742
VDAC3	0.015695
MRPS6	0.015673
MAN1C1	0.015651
NUDC	-0.015648
DBF4	-0.015617
RPN1	0.015601
APCDD1	0.015600
GLUL	0.015561
EIF2S1	-0.015560
UBALD2	-0.015546
YTHDF1	-0.015544
PDCD5	0.015533
COX6B1	0.015488
MDK	-0.015446
PPIA	0.015442
TUBB2B	-0.015365
DLC1	0.015351
VDAC1	-0.015304
HNRNPR	0.015287