!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!gene	LRRK2
!cell	ESC/iPSC
!perturbation	Parkinson's disease  homozygous LRRK2 mutation
!disease	Parkinson's disease
!end_metadata
NLRP2	0.111238
PEG3	0.102278
DACT1	-0.080520
SPP1	-0.072767
ANXA1	-0.072560
TIMP4	-0.072443
LEFTY1	-0.070537
SMAD7	-0.067402
GREM1	-0.066446
GABRA1	-0.064393
TNFAIP6	-0.064299
CHCHD2	-0.064194
POMZP3	0.062808
DDIT4	0.060361
LHFP	-0.060141
MYH2	-0.058898
CYP26A1	0.057430
CLC	-0.056099
DAZL	0.054041
GDF3	-0.053146
H1F0	0.051970
TXNIP	0.051208
GTF2H2B	0.051138
TAC1	-0.050003
RWDD2B	0.049744
NPTX1	0.048731
AFP	-0.048594
NEDD9	-0.048278
PVALB	0.045441
SLC7A5	-0.044937
PPP1R17	-0.044581
CAV1	-0.044576
RPRM	-0.044523
ZNF562	0.044022
AOC3	0.043834
WIF1	-0.043272
ANXA3	-0.042818
ABCG2	-0.042610
RLN2	0.042331
SLC12A1	-0.042255
CDKN1A	0.042224
AMIGO2	-0.042205
BST2	0.042166
STON1	0.041928
BCHE	0.041454
TUBBP5	0.041314
NR5A2	-0.041298
MIR22HG	-0.041137
CAMTA1	0.041048
QPCT	0.040645
HMOX1	-0.040499
ZNF516	0.040338
TEX14	-0.040057
MLLT4-AS1	0.039911
CCDC177	0.039229
LMO1	0.039072
PCDH8	-0.038674
NAALAD2	0.038518
TRPV1	0.038517
HAPLN1	-0.038261
SCG2	0.038150
LRAT	-0.037958
PLCL2	0.037843
GPM6A	0.037765
RFPL3S	0.037744
TSPYL5	0.037457
ZBED8	0.037193
MAGEL2	0.036901
DDX60	0.036846
NQO1	-0.036795
AGBL2	0.036782
IFIT1	0.036601
HIST1H2AC	-0.036572
BNIP3	0.036485
DNM3	-0.036090
RASA4	0.036017
MYC	-0.035930
ELAVL4	0.035467
DUSP5	-0.035203
ZFP2	0.034795
ZFR2	0.034672
FOXL2	-0.034645
AMOTL2	-0.034636
TCEA2	0.034366
CHP2	0.034295
SIX3	0.034239
GSAP	0.034083
SNAI2	-0.033927
SST	-0.033680
GLTP	-0.033185
ENPP2	-0.032916
TTN	-0.032791
TNFRSF11B	-0.032529
SEC14L5	0.032481
GSTT1	0.032418
SPATA7	0.032402
THNSL1	0.032394
ZMAT3	0.032348
PROS1	0.032227
CHML	-0.032188
EIF1AY	-0.032095
GUCA1A	0.032088
OPCML	0.032032
CACNA2D2	0.031897
ACTN3	0.031838
PCYOX1L	0.031817
ZNF248	0.031781
NEFL	0.031664
TTYH1	0.031600
ENO2	0.031424
ZNF280D	0.031357
ISG20	0.031330
DDB2	0.031273
SERPINE1	-0.031116
ECHDC3	0.031083
GARS	-0.031028
NUDT6	0.031013
DRAM1	0.030972
MST1L	0.030957
ADI1	-0.030635
FYCO1	0.030519
TTLL1	0.030505
ADM	-0.030504
DHCR24	-0.030450
EGR1	0.030411
FAM129A	-0.030379
LIPG	-0.030337
YPEL1	0.030149
SESN1	0.030145
CHORDC1	-0.030031
HHLA3	0.030000
FZD10	-0.029788
PBLD	0.029761
SPINK1	0.029602
AHNAK2	0.029589
ZNF37BP	0.029538
DNASE1L1	0.029517
SUSD5	-0.029393
C2orf68	0.029267
PLA2G3	-0.029250
FRZB	0.029219
POSTN	-0.029064
PPP1R3C	0.029039
TCFL5	0.028997
KRCC1	0.028874
RTN1	0.028708
TRAF5	0.028686
ANKRD36	0.028662
NID2	0.028638
CCT6B	0.028617
CALML4	0.028589
TUBG2	0.028561
CROCCP2	0.028477
LY75	0.028389
LOC202181	0.028370
LPAR6	-0.028356
S100A10	-0.028313
PEA15	-0.028293
MPP6	-0.028253
PAMR1	0.028252
ZBTB3	-0.028226
GOLGA8H	0.028226
AHNAK	0.028209
GPR137B	0.028182
ZNF137P	0.028151
ACSM3	0.028143
TDRD7	0.027948
ST8SIA3	-0.027936
CAV2	-0.027897
PTX3	-0.027842
PPFIA4	0.027799
LAMA3	-0.027791
SLC7A11	-0.027782
PLAT	-0.027755
TFCP2	0.027642
RAB3B	-0.027622
SLC2A10	0.027582
SS18L1	0.027558
LEFTY2	-0.027549
ACOX2	-0.027526
PLA2G4C	-0.027496
FOXD3	-0.027483
NEDD4	-0.027481
ECHDC2	0.027437
MYO6	0.027416
SKIL	-0.027397
TDRD12	0.027340
COL9A3	0.027336
BAMBI	-0.027290
CCNE2	-0.027231
FDXR	0.027227
LUM	-0.027225
BZRAP1	0.027145
CYP51A1	-0.027131
OXSM	0.027088
CCR10	0.027068
TP53TG1	0.027010
PPP1R16B	-0.026976
UPK1A	0.026926
PVRL3	-0.026918
PHYH	0.026914
LINC00339	0.026823
LOC100129973	0.026810
GCLM	-0.026763
PDCD4	0.026737
RNASE4	0.026707
HIST1H4H	-0.026654
SEMA3A	-0.026604
PSPH	-0.026502
ISL1	-0.026497
MOXD1	0.026488
LAMA5	0.026422
DUSP6	-0.026343
PIGB	0.026309
RALGPS1	0.026247
EFS	0.026238
DDX58	-0.026152
GNAZ	0.026139
GABRB3	-0.026115
CH25H	-0.026047
CYBRD1	-0.026031
C1RL	0.026014
GABRP	0.026010
SCG5	0.025984
STEAP1	-0.025954
TRHDE	-0.025941
TNNI3	0.025916
LPL	0.025892
NPY	-0.025858
MXRA5	0.025836
TXNRD3	0.025720
CD72	0.025698
CLDN3	0.025685
MVP	0.025680
H1FX	0.025624
ARID5B	-0.025598
USP36	0.025585
GAA	0.025518
ZNF83	0.025500
CTGF	-0.025465
HIST1H1C	-0.025421
ASGR1	0.025363
ALCAM	0.025355
INPP5E	0.025344
TCL1A	0.025222
ZNRD1-AS1	0.025216
C9orf40	0.025195
IPP	0.025138
CEMIP	-0.025136
LOC441204	0.025118
HPN	0.025102
BMP2	-0.025046
ST20	0.025037
BTN3A3	0.025033
TRAPPC6A	0.025021
MX1	0.024948
GALNT12	0.024894
PCDHA6	-0.024870
PRODH	0.024737
MATN3	-0.024658
LSM14B	0.024651
PARM1	-0.024630
CTSB	0.024627
SPIB	-0.024612
WNT5A	-0.024589
ODC1	-0.024557
SQLE	-0.024524
KDM4D	0.024497
HMGCR	-0.024483
PDE4B	-0.024408
SLMO2	0.024405
SEMA3G	0.024383
KLKB1	-0.024328
C20orf195	0.024296
CECR1	0.024239
SPATA20	0.024236
NLRX1	0.024234
USP9X	0.024182
CRYBB2P1	-0.024149
GLS2	0.024130
ZMYM2	0.024063
HIST1H2BD	-0.024046
MCMBP	-0.024021
SYT11	-0.023955
NUAK1	-0.023942
GLRX2	-0.023933
COL11A1	-0.023907
IDI1	-0.023905
CLGN	0.023872
METTL7A	-0.023856
TNFRSF10C	0.023832
CD99	0.023741
PTER	0.023700
WSB1	0.023693
LSS	-0.023691
IFI16	0.023672
P4HA2	0.023652
GCAT	0.023646
B3GALT1	-0.023641
INSIG1	-0.023615
GPC3	0.023593
LHX2	-0.023578
PF4	-0.023571
CYB5B	-0.023562
COL5A2	-0.023525
BMP4	-0.023508
NOD1	0.023502
COL3A1	-0.023386
BCL6	0.023384
INSM1	-0.023372
PRR7	0.023369
MSRB2	0.023359
TNFRSF8	-0.023335
ZNF512B	0.023275
PGM1	0.023243
CARF	0.023226
RBKS	0.023136
NAT9	0.023119
MACROD1	0.023118
RHOBTB3	0.023105
FEZ1	0.023047
R3HDM2	0.023037
SLC16A10	-0.023007
RRAS	0.022996
SLC39A14	-0.022980
P4HTM	0.022960
OPTN	0.022925
MYH3	0.022901
ANKRA2	0.022863
ZNF767P	0.022861
ST3GAL6	0.022851
AASS	0.022850
GAL	-0.022821
CSRP1	-0.022809
MEIS3P1	0.022797
CLIP3	0.022786
GALT	0.022770
MXRA7	0.022770
VSNL1	-0.022768
CBR3	-0.022739
GNAL	0.022717
OGDHL	0.022679
TMEM57	-0.022670
AMH	-0.022666
LRRTM4	-0.022622
SOCS2	-0.022560
SFRP1	0.022539
NR3C1	-0.022535
PSMB9	0.022533
CA2	-0.022482
FAM131A	0.022433
SEMG1	-0.022402
ZNF226	0.022391
CTNND2	0.022352
GSDMB	0.022339
HMGCS1	-0.022336
TFPI2	-0.022316
PGPEP1	-0.022264
CLCN2	0.022255
CBR4	0.022180
TK2	0.022138
DDHD2	0.022127
HMGCL	0.022123
LMF1	0.022113
SCD	-0.022105
GJA4	-0.022104
NDUFAF3	0.022085
MMP10	-0.022078
BAG2	-0.022072
EPHA4	0.022069
DOCK4	-0.022051
RBM14	-0.022042
FABP5	-0.022037
RNASET2	0.022016
SLC2A4RG	0.022012
RAB6B	0.022002
HGSNAT	0.021994
LYN	-0.021970
CALB1	-0.021963
C1orf115	0.021962
PLA2G7	0.021953
TARBP1	0.021948
FGF4	-0.021937
ABCA5	-0.021893
CCNA1	-0.021870
BCL11B	-0.021849
BNIP3L	0.021825
RIT2	-0.021815
ALDH5A1	0.021803
PNP	-0.021802
UBXN8	-0.021795
PDZK1	0.021773
GATM	0.021768
SRRD	-0.021743
FERMT1	-0.021718
AJAP1	-0.021709
KBTBD11	0.021688
KLF7	-0.021641
PCMTD2	0.021615
ACAT2	-0.021586
PCYT1B	-0.021578
TFPI	-0.021566
MXI1	0.021491
C3	0.021481
PHC2	0.021453
KLF11	0.021448
ATP1A2	0.021441
BCL2L2	0.021411
MTL5	0.021408
DOCK3	0.021400
SSPN	0.021367
NOTCH2NL	0.021356
ZSCAN18	0.021315
ZNF529	0.021302
IFT140	0.021263
CHIC2	-0.021262
PWAR5	0.021251
ADAMTS1	-0.021216
SPINK2	0.021193
PSTPIP2	0.021150
ATP1B2	0.021129
PLCG2	0.021117
RNF128	-0.021101
FCHSD2	0.021099
RPL39L	0.021094
CTNNA2	0.021061
UCKL1	0.021060
MT1E	0.021046
PDGFD	-0.021030
ZEB2	0.020991
WDR19	0.020983
CCNG2	0.020953
GLCE	0.020935
TP53I3	-0.020907
TRBC1	-0.020903
PNMAL1	0.020894
ZBTB44	-0.020874
ANGPT1	-0.020854
SFN	-0.020835
MYOZ1	0.020800
USP3	0.020796
CYP2R1	0.020778
ERVMER34-1	-0.020770
LYRM9	0.020760
RND3	-0.020750
C17orf85	-0.020749
ADCY7	0.020738
C5orf45	0.020723
RRM2	-0.020714
PIDD1	0.020699
FOXO4	-0.020695
TMEM158	0.020626
CREB5	-0.020614
VCAN	-0.020602
ZNF133	0.020564
BBS10	0.020563
GPX3	-0.020562
PTPN20B	0.020546
KIAA1107	0.020542
METTL21B	0.020538
ALDOC	0.020500
SYT1	-0.020500
UBIAD1	-0.020461
HLTF	0.020460
HDHD1	-0.020447
ZNF354A	0.020445
ACYP1	0.020443
FBXO22	0.020433
OSGEP	-0.020433
SUV420H1	-0.020382
STAG3L1	0.020352
DHCR7	-0.020340
ADAMTS5	-0.020338
BEND5	0.020338
SCAI	0.020332
LOC81691	0.020302
PEX11A	0.020289
EFHD1	0.020271
NDNF	0.020205
MLLT11	-0.020205
ZNF702P	0.020184
EFR3A	-0.020183
MGMT	0.020172
HIST1H2BK	-0.020160
DLGAP1	0.020151
BRINP1	-0.020146
COL4A5	0.020128
ID2	0.020114
MTRF1	0.020105
BAX	0.020088
UNC119	0.020066
GRPR	-0.020017
GATA3	-0.019996
TJP3	0.019936
RGN	-0.019931
HS1BP3	0.019922
DAB2	-0.019919
PRKCB	0.019886
WDR33	0.019866
ATP10D	-0.019857