!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Bexarotene
!smiles	CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
!drugbank_id	DB00307
!pubchem_cid	82146
!cell_type	LIVER from Sprague Dawleys
!organism	rat
!end_metadata
SCD	0.283430
FASN	0.252969
PLIN2	0.191273
TDO2	-0.171164
KCTD13	0.164833
BHMT	0.163655
GC	-0.159662
ACAA2	0.147505
CDO1	-0.144179
HSPA8	-0.143483
ABCD3	0.142433
APOA2	0.138976
INSIG1	0.137413
CYP2E1	-0.122559
PAH	-0.115498
COMT	-0.114308
AHSG	-0.110442
EHHADH	0.109499
METTL7B	0.107106
CYP1A2	-0.104795
PON1	-0.101829
DBI	0.098582
ACOX1	0.098228
HSD17B2	-0.097266
HP	0.093425
SRD5A1	-0.089618
FBP1	0.087482
RNASE4	0.084515
SPP2	-0.083581
FABP1	0.083367
MPC1	-0.082352
COX1	0.082175
AGT	0.080970
PABPC4	0.080755
EPHX1	0.080581
KYNU	0.080217
HSP90AB1	-0.078876
RPS26	-0.075910
SORD	-0.075457
APOH	-0.073983
CPT2	0.073478
ABCB11	0.071943
CTH	0.071160
RPL8	-0.070192
SLC41A2	-0.069282
VTN	-0.068997
TTR	-0.068699
AMBP	-0.068340
ACTB	-0.067267
TAT	-0.066969
PDK2	0.066488
KNG1	0.066457
IGFBP2	0.064423
FTL	-0.063917
ACADM	0.063745
SULT2A1	-0.063205
COX2	0.061337
MSMO1	-0.060903
HMGCS1	-0.059429
AMACR	0.059326
ECI1	0.058814
RPLP0	-0.058342
TMBIM6	0.057925
GSTM5	-0.057899
HSP90B1	-0.057847
LIPA	-0.056411
UPB1	0.055051
ACSL1	0.054438
ALDOB	-0.054268
HMGCS2	0.054041
ATP5B	0.053197
HSP90AA1	-0.052723
HRSP12	-0.051123
ARG1	-0.051113
ALDH1A1	0.050906
ID2	-0.050538
FABP5	0.050245
RPS21	0.049931
IGFBP1	0.048945
RPL17	-0.048944
TTPA	-0.048810
RPS27A	-0.048573
APOA1	-0.048330
NR0B2	0.048195
RPL37	-0.047664
PDK4	0.046963
ASL	-0.046407
ST6GAL1	-0.046338
ALB	0.045245
AQP9	-0.044462
PIGR	-0.044180
SDS	-0.043971
BSG	0.043779
CPS1	-0.042879
OAT	0.042433
RGN	-0.042020
B2M	-0.041432
SERPINA3	-0.040545
RPS17	-0.040484
GPD1	0.040463
SERPING1	-0.039853
AFM	-0.039536
ITM2B	-0.039502
DNAJA1	-0.039346
ACSL5	0.039064
APCS	-0.038824
ATP6	0.038592
COX3	0.038258
HADHA	0.038257
PXMP2	0.038200
ECH1	0.038148
HACL1	0.037838
RPS13	-0.037472
ACLY	0.037347
GHR	-0.036866
RPL12	-0.036668
COX4I1	0.036416
RPS6	-0.036334
C9	0.035654
MDH1	0.035312
RPS27L	-0.034832
POR	0.034616
CD81	-0.034574
GJB1	-0.034443
DECR2	0.034419
ABCC2	-0.033981
SERPIND1	-0.033065
DPYS	-0.033013
PDLIM1	0.032683
THRSP	0.032394
TPI1	-0.032331
CPT1A	0.032322
RPL6	-0.032230
ALPL	0.032178
PDIA6	-0.032140
F9	-0.031665
HPD	0.031478
TST	-0.031450
ITIH3	-0.031312
COPZ1	0.031240
FDX1	0.031164
RPS4Y1	-0.030504
SLC27A2	0.030472
RPL39	-0.030452
RPL31	-0.030329
DECR1	0.030257
GAPDH	0.030090
MGST1	0.030085
IDH1	-0.029854
RBP4	-0.029667
CYTB	0.029535
SREBF1	0.029402
PGRMC1	-0.029366
RPL10	-0.028848
CYB5A	-0.028571
TMED2	-0.028499
PAPSS2	-0.028485
SEPP1	-0.028457
KLKB1	-0.028406
RPL7A	-0.028368
CYP17A1	0.028314
MAOB	-0.028191
C8B	-0.028073
RPL11	-0.027998
ACAT1	0.027804
ATP5A1	-0.027626
IFITM3	-0.027412
ME1	0.027244
ALDH1L1	0.027238
RPL4	-0.027145
PEX11A	0.027102
ITIH4	-0.027092
SDC2	-0.027072
APOM	-0.026968
RPS14	-0.026491
CLU	-0.026108
LDHA	0.026038
AVPR1A	0.025694
CTSC	-0.025521
FABP6	0.025478
P2RY2	0.024983
CYCS	-0.024937
CYC1	0.024708
MGST2	0.024633
FN1	-0.024602
DDT	-0.024535
GSTO1	-0.023853
RPS8	-0.023557
PSMD11	0.023512
RPL13A	-0.023496
PLG	0.023329
TPST2	0.023325
HADHB	0.023273
RPS16	-0.023214
ALDH6A1	-0.023144
TKT	0.022967
TCN2	-0.022935
XDH	-0.022875
GLUD1	-0.022840
SLC37A4	-0.022611
ERRFI1	-0.022549
RPS23	-0.022455
UGDH	-0.022451
PDIA3	-0.022326
ND5	0.022198
RPL28	-0.022159
PEBP1	-0.022157
DAK	0.022148
MAT1A	0.022078
G0S2	-0.022052
RPL22	0.021949
HPX	0.021931
PDIA4	-0.021859
ACO1	0.021851
RPL15	-0.021662
RBPMS	0.021628
CST3	-0.021556
ALDH7A1	-0.021555
ACAT2	0.021532
CTSB	0.021362
UBC	0.021345
IL33	-0.021143
APOB	-0.021088
FMO1	-0.021015
CLTC	-0.020869
HMGCL	0.020691
SLC40A1	-0.020577
MORF4L2	-0.020446
BTG1	-0.020413
CTSV	-0.020393
NDRG2	-0.020324
FTH1	-0.020162
HSPA5	-0.019970
GCKR	0.019964
FAU	0.019947
SERPINA10	-0.019858
AKR1A1	-0.019858
MBL2	-0.019800
F2	0.019766
GPX1	0.019719
LITAF	0.019696
SLC2A2	-0.019582
CD74	-0.019364
SERPINA6	0.019243
RPL24	-0.019102
COX6A1	0.018965
TUBA1C	-0.018915
RPS5	-0.018914
CNN3	-0.018908
RPS3	-0.018883
UBE2J2	0.018851
HAGH	-0.018790
TECR	0.018749
CANX	-0.018370
RPL26	0.018360
HNRNPK	-0.018226
HAAO	0.018137
GNMT	-0.018126
HSPE1	-0.017844
DYNLL1	-0.017815
ACTG1	-0.017798
RPL18	-0.017644
SEC61B	-0.017603
ETNK2	-0.017363
IGFALS	-0.017335
RBP1	-0.017318
DPYD	-0.017315
ADK	-0.017185
ALDH2	-0.017093
ATP5G2	-0.017058
TTC36	0.017030
B4GALNT1	0.017024
ATP6V0C	-0.016865
ZFAND6	-0.016716
FAH	0.016671
MTHFD1	0.016654
RPL36AL	0.016511
RPL21	0.016371
FDFT1	0.016366
CCND1	0.016322
PRLR	-0.016203
RPS11	-0.016183
AUH	-0.016162
TSC22D1	-0.016071
PTP4A1	-0.016022
SEPHS2	-0.015864
NDUFB2	0.015854
EEF1G	-0.015604
RPP21	-0.015468
AK4	0.015465
RPL23	-0.015430
MTCH2	-0.015408
DBP	-0.015394
TMEM53	0.015304
PRDX1	-0.015291
GRINA	0.015231
PPIA	0.015220
POMP	0.015208
ADH1C	0.015182
YBX3	-0.015084
ATP1B1	0.015012
FGB	0.014909
NACA	-0.014791
G6PC	0.014724
MARC2	-0.014612
HSD17B10	0.014575
PHB2	-0.014564
GSTM2	0.014485
PPIB	-0.014479
SLC28A2	-0.014467
KRT8	0.014458
BNIP3L	0.014300
AZGP1	-0.014272
PSMA2	-0.014239
SLC22A7	0.014196
PRODH2	-0.014127
H2AFZ	-0.014104
CROT	0.014103
GAA	0.014023
PTPRF	-0.013950
GNAI3	-0.013809
HMGCR	-0.013758
SLC6A6	0.013620
RPL3	-0.013598
RPL18A	-0.013551
LIPC	-0.013547
ADRA1B	-0.013530
FKBP4	-0.013496
SEC61A1	-0.013414
DYNLRB1	0.013381
RPL19	-0.013329
NDUFA6	-0.013162
DACT2	0.012961
ACOT2	0.012835
SSR3	-0.012772
GSTK1	0.012754
GOT1	-0.012720
CCBL1	0.012585
HSPD1	-0.012556
TXNRD1	-0.012519
GTF2B	0.012427
RPL30	-0.012426
CALR	0.012410
FUCA1	0.012374
COX8A	0.012369
FGG	0.012288
ABHD14B	-0.012266
CFB	-0.012243
EEF1A1	0.012240
PFN1	-0.012021
ND2	-0.011978
NME2	0.011934
PTPLAD1	-0.011923
ATP5H	0.011912
TUFM	0.011887
GPX4	0.011831
COX7B	-0.011820
NDUFS7	0.011808
PPP2R5A	-0.011697
MRFAP1	0.011679
CTSS	-0.011604
HSD17B4	0.011590
CES1	-0.011579
DDX3X	-0.011551
FDPS	-0.011551
RAP1B	-0.011545
GCLC	-0.011525
OTC	-0.011518
RABAC1	-0.011517
C11orf73	-0.011516
CD36	0.011505
AMY2B	-0.011416
LGR4	-0.011411
MGST3	0.011342
CA5A	-0.011335
GNE	0.011308
GCGR	0.011249
BAAT	-0.011228
FGA	0.011221
RPSA	-0.011219
ATP6AP1	-0.011176
ACY1	-0.011139
GNAS	-0.011135
ATP5O	0.011051
GNB2L1	-0.011045
GABARAP	-0.010927
SLC25A20	0.010917
ARF4	-0.010859
ATP1B3	-0.010813
ALAD	-0.010787
SDCBP	-0.010745
PCYT2	0.010731
APOE	0.010666
TSPO	0.010634
ACACB	0.010584
TOR1AIP2	-0.010496
HPN	0.010352
STK39	0.010290
AP2M1	0.010233
AADAT	-0.010179
CLDN3	-0.010173
GNAI2	0.010147
CEBPB	0.010139
ITGB1	0.010130
CTSH	-0.010129
CXXC5	0.010116
CPQ	-0.010105
SLC10A1	0.010101
ACOX2	0.010031
AGXT	-0.010016
HNRNPA2B1	-0.010002
ONECUT1	-0.009961
RPS9	0.009959
NPHP1	-0.009956
TALDO1	0.009878
HSD3B7	0.009859
PCBD1	-0.009858
PSME1	-0.009835
SLC26A1	-0.009834
QDPR	-0.009823
DLAT	0.009809
IVD	0.009805
LIMK2	0.009793
PRDX6	-0.009792
COLQ	0.009752
CHKB	0.009652
NDUFA9	0.009594
RAF1	-0.009570
ECHS1	-0.009447
NCOA4	-0.009391
HES1	0.009364
SARDH	0.009299
PTTG1IP	-0.009297
PIM3	-0.009275
INF2	0.009262
GPT	0.009188
NUTF2	-0.009176
SIGMAR1	0.009176
HSPH1	-0.009173
SFXN1	-0.009142
SQSTM1	-0.009107
RPS15A	-0.009096
BECN1	-0.009081
IMPA1	-0.009047
NFE2L2	-0.009044
ALAS1	-0.009037
MAPK3	0.009010
RPL14	-0.009007
CHORDC1	-0.009003
SOD1	-0.008966
KRT18	0.008951
ASS1	0.008918
DIO1	-0.008852
RPN2	0.008802
MPST	-0.008797
PSMB5	0.008790
HNRNPF	-0.008750
RPL5	-0.008734
KHK	0.008732
ASPG	0.008673
SPINT2	0.008659
SLC22A18	-0.008655
AGTR1	-0.008648
ND4	-0.008618
LCAT	-0.008614
SQLE	-0.008521
NDUFV3	-0.008493
ASGR2	-0.008482
SULT1B1	0.008475
ALDH3A2	-0.008462
CLEC4F	0.008449
C1QB	-0.008446
SLC25A5	-0.008421
SLC22A1	-0.008393
GCLM	-0.008373
RXRG	0.008371
CAPNS1	0.008345
RPS6KA1	0.008322
PSMA6	-0.008292
TRAP1	0.008280
ACADL	0.008249
TMEM59	-0.008222
ACADS	0.008210
RPN1	-0.008192
ORMDL2	-0.008181
CCNL1	-0.008140
DDC	-0.008138
AKR1D1	-0.008075
NDUFB9	0.008072
ACSL4	-0.008072
SEC62	-0.008060
HYOU1	-0.008060
SLCO2A1	0.008030
CAPZA2	-0.007999
PROC	-0.007980
RPL27A	-0.007954
AK2	-0.007934
CDIPT	-0.007919
PEX14	0.007918
C3	0.007875