!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	VX
!smiles	CCOP(=O)(C)SCCN(C(C)C)C(C)C
!pubchem_cid	39793
!cell_type	hNHEPS Hepatocytes - 6 Hours after exposure with 0.1 μM
!organism	human
!end_metadata
TENM2	-0.070792
KIAA0907	0.068492
SERPINB2	0.059087
GPR34	-0.058700
CYP1B1	0.058537
ID1	-0.055601
CYP2A6	-0.055489
PTX3	-0.053258
ADAMDEC1	-0.050786
RNF148	0.048665
CCDC102B	-0.048472
CYP1A2	-0.047487
HMCN1	-0.047443
RNASE6	-0.046581
LXN	-0.043484
LOC149703	-0.042922
INSC	-0.042237
PTGFR	0.041985
LINC01093	-0.041965
LEAP2	-0.040449
MS4A4A	-0.040264
IL33	-0.040235
CYP4A22	-0.040017
DACT1	-0.039935
C1orf162	-0.039753
CHAC1	-0.039449
TGFB1I1	-0.039344
FBLN5	-0.039309
PTGS2	-0.038184
MYOT	-0.038015
PXDN	-0.037989
PRR16	-0.037826
PLAT	-0.037801
MS4A7	-0.037112
CYP2B7P	-0.037082
PTPRZ1	-0.036240
FICD	0.036190
ADORA3	-0.036032
PLA2G4A	-0.035570
SLC23A1	-0.035204
C3AR1	-0.035153
TFPI2	-0.034960
LOC101928505	-0.034697
FBXO16	0.034600
EVI2B	-0.034514
SKAP1	-0.034306
SPARCL1	-0.034087
KCTD12	-0.033683
AADACP1	-0.033601
ID3	-0.033581
CRYAB	-0.033527
VCAN	-0.033513
ALDH3A1	-0.033510
VEGFC	-0.033357
LY96	-0.033080
GLYAT	-0.033005
FOXF1	-0.032738
LYZ	-0.032674
COL4A1	-0.032582
MRAP	-0.032564
CYP2A7	-0.032444
COLEC11	-0.032386
ELMO1	-0.032361
PIK3C2G	-0.032125
IP6K3	-0.032068
FPR3	-0.032027
GBA3	-0.032001
TYROBP	-0.031929
C1QB	-0.031826
PLIN1	-0.031712
COL6A3	-0.031535
MMP12	0.031458
LECT2	-0.031413
NQO1	-0.031215
MIR22HG	0.031031
FGF14	-0.030965
THBS2	-0.030949
FGF21	-0.030813
CECR1	-0.030742
DDX43	0.030720
THAP5	0.030399
LOC154761	0.030284
IL13RA2	-0.030177
HTR2B	-0.030082
PRKAR2B	-0.030057
PMEPA1	-0.029998
HCLS1	-0.029803
COTL1	-0.029801
IGJ	-0.029660
CTHRC1	-0.029551
FKBP14	0.029471
HERPUD1	0.029449
DNAJB9	0.029378
CRP	0.029352
SLC7A7	-0.029320
RTP3	-0.029309
NEURL1B	-0.029126
GPM6B	-0.028917
AKR1D1	-0.028876
ASPN	-0.028675
EPB41L4A-AS1	0.028647
SLC10A1	-0.028589
COG3	0.028541
OLFML2B	-0.028501
ALMS1-IT1	0.028397
C9orf152	-0.028067
PTBP2	0.028014
ZMYND12	-0.027997
ACBD4	-0.027984
UPP2	-0.027972
LTBP2	-0.027807
C1orf109	0.027662
ELF3	-0.027588
FAM111B	-0.027519
NEXN	-0.027461
BASP1	-0.027428
DEPDC1	-0.027416
OLFML3	-0.027405
ACSL3	-0.027361
NCR3LG1	0.027293
MAB21L3	-0.027275
TYRP1	-0.027248
CYP2B6	-0.027202
OTC	-0.027172
LOC101928858	0.027071
IGFBP5	-0.027058
VSIG10L	-0.027031
LUM	-0.026982
C7	-0.026973
TSPYL5	-0.026920
ITGBL1	-0.026894
COL4A2	-0.026885
PLA2G7	-0.026855
KCTD11	0.026798
ZBED8	0.026715
LRRK2	-0.026658
CPED1	-0.026656
FCER1G	-0.026648
UTS2B	-0.026622
SRPX	-0.026496
NRXN2	-0.026297
KBTBD8	0.026272
SNHG1	0.026243
VSIG4	-0.026216
PLAU	-0.026163
RWDD2A	0.026159
LMNB1	-0.026024
LOC100507634	0.025979
ENTPD7	0.025951
SULT2A1	-0.025937
PIPOX	-0.025783
ANKRD1	-0.025723
HNF4A-AS1	-0.025665
ANGPTL4	-0.025662
HOGA1	-0.025630
MTA2	0.025629
C1QC	-0.025566
GPX8	-0.025548
ACTR3B	0.025482
BICC1	-0.025458
IL18	-0.025373
TTC39B	-0.025366
LONRF2	0.025357
CYP4X1	-0.025356
R3HDM2	-0.025313
COL5A2	-0.025260
RAB34	-0.025225
CYP26A1	-0.025213
EID3	0.025181
TIMP1	-0.025164
COL1A2	-0.025139
MAP1B	-0.025087
SLC16A4	-0.025083
CKAP2L	-0.025034
FOSB	-0.025015
SEMA3C	-0.025003
PTGS1	-0.025003
IYD	-0.024962
ROBO1	-0.024924
SLITRK3	0.024918
GNAL	-0.024883
FGL2	-0.024865
ZSCAN16	0.024794
GSTA3	-0.024703
TM6SF1	-0.024658
PSMD9	0.024653
TAT	-0.024629
TMEM163	0.024611
TM7SF2	-0.024583
LOC101927934	-0.024543
PIR	-0.024533
SLC4A4	-0.024513
MX1	0.024503
SNHG15	0.024481
TFF1	-0.024436
S100A4	-0.024419
RAB7B	0.024419
ARRDC4	0.024357
GPR37	0.024350
AKR1B1	-0.024331
FASTKD5	0.024322
MGP	-0.024290
LRRC19	-0.024281
FBXO8	-0.024233
CCR1	-0.024231
PRMT9	0.024040
SLC25A25-AS1	-0.023986
PP7080	0.023959
LOC101927851	-0.023945
CACNA2D1	-0.023898
H19	-0.023871
APOF	-0.023856
HAO2	-0.023827
LRRC8E	0.023786
NOV	-0.023773
WISP1	-0.023758
FKTN	-0.023731
PRTFDC1	-0.023698
FBN1	-0.023691
ZFPM2	-0.023674
IFI16	-0.023662
ACSM2A	-0.023652
RMI2	-0.023621
LOC101928565	-0.023551
N4BP2	0.023547
MOGAT2	-0.023544
LOC652993	-0.023473
TGIF2	0.023424
MAMDC2	-0.023415
CAMSAP3	0.023371
LGALS4	-0.023364
SLC38A6	-0.023360
SLC35G2	0.023357
HLA-DRA	-0.023356
ZNF385B	0.023338
C1QA	-0.023336
LYSMD3	0.023332
ITGA2	-0.023331
CEP55	-0.023316
TIMP3	-0.023280
SLC22A1	-0.023248
THBD	-0.023222
AXL	-0.023172
WRN	0.023127
JUNB	-0.023099
GSAP	-0.023066
DAO	-0.023058
BTBD3	0.023029
ANXA1	-0.023023
METTL12	0.023004
SCFD2	-0.023003
HSD3B1	-0.022994
RBP5	-0.022953
ZNF680	0.022908
EDNRA	-0.022897
CTSK	-0.022845
LINC00621	0.022827
RNF4	0.022818
TMEM255A	-0.022794
SERPINE1	-0.022765
LINC00886	-0.022725
PAPPA	-0.022707
ACP5	-0.022665
ZNF652	0.022655
WDR45B	0.022647
C19orf80	-0.022634
CDH19	-0.022631
TUBGCP5	0.022628
COLEC10	-0.022615
FLJ22763	-0.022605
TTR	-0.022593
NCKAP5	-0.022562
GPNMB	-0.022559
VCAM1	-0.022448
AOC2	0.022426
ACOX2	-0.022413
TMEM53	-0.022395
EXTL2	-0.022386
SURF6	0.022383
MPDZ	-0.022344
HSPA13	0.022339
TNFRSF21	-0.022306
DNAJB4	0.022293
KCNJ8	0.022273
ARSK	0.022271
TIMP2	-0.022255
LOC284242	0.022228
SLCO2B1	-0.022070
ATXN1L	0.022046
RBBP5	0.021993
TIGD1	0.021939
CNTLN	-0.021925
R3HCC1L	0.021902
SMG1P5	-0.021846
GNPDA2	0.021811
SPARC	-0.021809
ARL14	0.021809
CCL2	-0.021802
CD52	-0.021796
ICE1	0.021784
MED10	0.021727
DEDD2	0.021708
LOC157562	0.021704
LOC100132891	-0.021696
RNF113A	0.021689
FOLH1B	-0.021686
TMEM98	-0.021685
C10orf126	-0.021679
EPHX1	-0.021678
PAPD5	0.021645
SALL1	0.021626
SHROOM2	0.021624
LOC100506870	-0.021615
SLC16A14	0.021612
CYP4F3	-0.021574
E2F8	-0.021570
C17orf97	0.021567
TBCK	-0.021565
C6orf47	0.021548
TRIM27	0.021518
KIAA1107	-0.021488
PCED1B	-0.021488
UAP1	0.021468
FAM217B	0.021466
NETO2	-0.021461
BHMT	-0.021425
DFNA5	-0.021375
PPAPDC1A	-0.021354
NID2	-0.021351
MTHFD2	-0.021257
AMIGO2	-0.021239
ZNF165	0.021235
TRIM39	0.021232
RAB31	-0.021212
NAP1L3	-0.021210
NUP160	0.021187
VGLL3	-0.021174
NDN	-0.021170
TMEM139	-0.021119
MOGAT3	-0.021108
CCDC134	0.021067
LRRC58	0.021065
MGC32805	-0.021054
MAN1C1	-0.021046
GPER1	0.021021
SPC25	-0.021019
C2orf44	0.021016
GABARAPL1	0.021006
RSRP1	0.020989
DCN	-0.020953
WDR76	-0.020939
ZNF263	0.020924
TIMP4	-0.020909
ARHGAP6	-0.020892
PLP1	-0.020886
TLR1	0.020845
LINC00341	-0.020835
DENND2D	-0.020832
GPR137C	0.020783
GORASP2	0.020761
EVI2A	-0.020697
ZNF786	0.020638
EFCAB7	0.020616
HMGCS2	-0.020564
SNHG7	0.020562
PHF14	0.020561
TNFSF4	-0.020537
PWWP2A	0.020534
ZNF367	-0.020530
RORC	-0.020525
SLC16A10	-0.020490
DFFB	0.020434
ENY2	0.020426
SLC17A3	-0.020382
C1orf52	0.020373
TTC30B	0.020366
FMO1	-0.020344
WDR53	0.020337
LOC100134445	0.020337
BAG5	0.020315
SELE	-0.020303
CSF1R	-0.020301
EAF1	0.020271
CDC42	0.020257
LY86	-0.020207
SUGCT	-0.020201
LINC00238	-0.020185
SIGLEC10	-0.020167
AGTR1	-0.020119
S100P	-0.020109
GMFG	-0.020095
DET1	-0.020086
IGFBP7	-0.020086
TMEM170B	0.020073
C3orf52	0.020072
SLC13A5	0.020037
NFXL1	0.020035
SLC25A34	-0.020028
GNL3	0.020011
SEC22A	0.019992
CD163	-0.019981
PFKFB3	0.019975
C1orf168	-0.019969
FMO4	-0.019926
GNL2	0.019924
CHCHD7	0.019917
LRRC8A	0.019896
DUSP12	0.019894
NUP50-AS1	-0.019868
RBM25	0.019853
FMNL2	-0.019840
UBE2J1	0.019839
L3MBTL4	-0.019815
EDNRB	-0.019794
MPZ	-0.019786
LOC100505727	0.019783
MPV17	-0.019745
KIF15	-0.019736
AKAP17A	0.019726
BBS12	0.019719
DDC	-0.019715
MGC70870	-0.019704
OSGIN1	0.019697
MBL1P	0.019690
FOXA1	0.019671
KIAA1211	-0.019668
ZSCAN21	0.019661
ANKRD17	0.019660
PTGER2	-0.019638
ADIRF	-0.019638
TAF1A-AS1	-0.019636
CRIM1	-0.019636
ACOT13	-0.019611
CPVL	-0.019591
AGXT	-0.019560
ANK3	-0.019557
TVP23B	0.019522
STAM	0.019490
FAM117A	0.019478
KBTBD6	0.019469
SUDS3	-0.019459
TUBA1A	-0.019430
ASAP2	-0.019429
HAUS3	0.019411
TCEAL7	-0.019408
LTBP1	-0.019402
FAM172A	-0.019388
ZNF225	0.019363
HLA-DMB	-0.019358
LPP-AS2	-0.019350
C15orf48	0.019300
ALOX15B	-0.019280
MALT1	0.019273
PDRG1	0.019263
SCAPER	-0.019250
SPRY3	0.019228
EFNA4	0.019218
LRIF1	0.019218
HEATR5A	-0.019209
KANK4	-0.019204
LOC100996579	0.019197
SOX7	0.019192
MIR100HG	-0.019175
DGAT1	-0.019164
FAM222A	0.019135
DDIT4	-0.019129
GNG11	-0.019126
ACE2	-0.019121
LOC285835	0.019115
PSMD11	0.019109
MPEG1	-0.019097
DCUN1D2	0.019096
KIF11	-0.019089
IL6	-0.019085
MAMLD1	0.019008
ITGB8	-0.019004
HMOX1	-0.019002
AFMID	0.018990
KMO	-0.018967
MS4A6A	-0.018943
TOLLIP-AS1	0.018940
PPP2CA	0.018919
SLAMF8	-0.018914
CYP4A11	-0.018883
GPR160	-0.018828
OMA1	-0.018821
HIST1H3A	0.018818
ZFP37	0.018791
MIS12	0.018769
MFSD9	0.018747
GMNC	0.018721
OVOS2	-0.018708
GAN	0.018644
TRPM8	-0.018633
ELOVL6	-0.018608
AIF1	-0.018595
CHI3L1	0.018557
DDIT3	-0.018539
DNM3OS	-0.018523
GFPT2	-0.018517