!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Tretinoin
!smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
!drugbank_id	DB00755
!pubchem_cid	444795
!cell_type	NB4 APL 9 acute promyelocytic leukemia cells - 72 Hours
!organism	human
!end_metadata
TGM2	0.063098
BPI	0.059735
CYTL1	-0.054168
SELL	0.053448
ALOX5AP	0.049184
CCL24	0.049143
FGR	0.045266
SNORD14E	-0.044601
PADI2	0.041793
DHRS3	0.041062
SNORD41	-0.040974
LYZ	-0.039981
MS4A3	-0.038984
GNG2	0.038529
EBF3	-0.038494
PRG2	-0.037677
HDC	-0.037467
MMP9	-0.037073
C1orf186	-0.036863
GPR97	0.036511
FFAR2	0.036326
S100A8	0.036037
LAMB3	0.035887
LHFP	-0.035390
FBP1	0.034945
PSMB9	0.034928
ICAM1	0.034677
PRAM1	0.034420
VIM	-0.033818
MAP7D3	-0.033732
PSMB8	0.033608
E2F5	-0.033305
ASB2	0.032747
OCR1	-0.032703
SNORA38B	-0.032697
SNORD4A	-0.032636
AMICA1	0.032632
KCNH4	0.032532
SNORA23	-0.032514
SLC2A5	0.032058
NCF2	0.032023
DCUN1D4	-0.031841
ECRP	-0.031745
NQO1	-0.031678
RAB27B	-0.031325
EMR3	0.031244
IFITM10	0.031197
PADI4	0.030959
SACS	-0.030936
DEFA4	0.030936
SNORD14C	-0.030746
CD52	0.030675
RCSD1	0.030114
CCDC66	-0.029914
RNU5D-1	0.029885
SERPINB1	0.029864
HK3	0.029790
CDC42EP3	-0.029688
CD300A	0.029655
CHAC2	-0.029385
RPP40	-0.029340
ITGB7	0.029187
PARGP1	-0.029096
CYP1B1	-0.029015
TNFAIP2	0.029010
HOMER1	-0.028965
RNF125	-0.028962
MORN2	-0.028931
PEA15	-0.028602
LRG1	0.028584
NARS2	-0.028556
CA8	-0.028510
OAS3	0.028490
SNORA71D	-0.028408
DTD2	-0.028360
IRF1	0.028207
MIR142	-0.028171
PKN1	0.027916
ATP5G1	-0.027854
FAM20C	0.027810
PAPD5	-0.027796
PLCB2	0.027733
USP17L6P	0.027725
PCGF6	-0.027720
SPP1	0.027592
MCEMP1	0.027588
FLJ36840	-0.027562
GEMIN5	-0.027468
ZNF146	-0.027442
TAF4B	-0.027169
CMSS1	-0.027117
SNORD4B	-0.027052
SDC2	-0.026954
NAF1	-0.026942
SLC7A11	-0.026868
CES1	0.026555
PARP14	0.026423
SNORA45A	-0.026406
RPGRIP1L	-0.026397
BCL11A	-0.026372
AHNAK	-0.026353
ASS1	-0.026223
NLRC4	0.026183
GINS2	-0.026021
SASS6	-0.025953
C1RL	0.025842
ARAP1	0.025793
SLA	0.025732
TMEM173	0.025653
ROPN1L	-0.025488
UBR3	-0.025476
RSU1	-0.025419
CTSG	-0.025318
TBL1X	-0.025298
SNORD115-24	0.025061
TAS2R14	-0.025013
DDIAS	-0.024957
GNG4	-0.024937
DAAM2	0.024825
ELOVL3	-0.024735
NT5DC2	-0.024642
SLC39A14	-0.024614
CCNE2	-0.024505
MIR600HG	-0.024481
FAM46C	-0.024453
LRRK2	0.024429
IFIT5	0.024407
UBXN8	-0.024404
MERTK	0.024381
PDE3B	-0.024308
PTPLB	-0.024266
SNORA20	-0.024232
RARRES3	0.024214
KIAA1147	-0.024185
TAS2R4	-0.024155
IL17RA	-0.024111
SEMA6B	0.024034
CSF3R	0.023938
CA2	-0.023905
POLE2	-0.023889
CST7	-0.023840
STK17B	-0.023782
RBP4	-0.023735
CHST11	-0.023721
LFNG	0.023643
STRADB	-0.023618
MYO9A	-0.023570
SRRD	-0.023488
ZNF675	-0.023486
MOK	-0.023480
ZRANB3	-0.023434
SLC44A1	0.023415
RGS1	0.023407
SMOX	0.023339
FLOT1	0.023232
MT1F	-0.023182
NCS1	-0.023145
MNAT1	-0.023126
SNORA24	-0.023101
PGAP1	-0.023060
CD101	0.023055
ITGAM	0.023034
C10orf54	0.023012
RPAP2	-0.022994
FCHSD2	-0.022987
MDK	0.022983
CEP83	-0.022977
HSPA4L	-0.022969
DCAF17	-0.022886
COX16	-0.022757
PIK3C2A	-0.022748
ESCO2	-0.022705
PSG8	0.022671
TMEM254	-0.022621
SELP	0.022609
TMEM261	-0.022595
DDHD1	-0.022562
RBMY2EP	0.022561
CXCR2	0.022531
TAF9B	-0.022474
PTGES	0.022449
LGALS3BP	0.022429
LSP1	0.022419
INPP5A	-0.022416
MIR15A	-0.022362
GCA	0.022354
ALMS1	-0.022342
EPAS1	0.022332
NOC3L	-0.022316
MRPS11	-0.022277
RPPH1	0.022210
ADA	0.022210
SPICE1	-0.022209
CFP	0.022206
MGST1	-0.022193
GM2A	0.022148
AAED1	-0.022145
CD38	0.022144
CTSH	-0.022139
ZNF597	-0.022132
SLC7A2	-0.022122
CCNT1	-0.022119
NUDT7	-0.022041
FAM210A	-0.022008
KIAA2026	-0.021984
ITGAX	0.021979
SNORD115-25	0.021979
RNF130	-0.021976
SNORD74	-0.021975
ZEB2	-0.021947
MT2A	-0.021914
ZBTB11	-0.021881
SPARC	-0.021878
SNORD116-14	0.021853
FASTKD3	-0.021849
MMP8	0.021812
HLA-G	0.021802
FNTB	-0.021728
IKZF5	-0.021716
SLC7A5	-0.021706
CLEC5A	-0.021599
CRTC3	-0.021584
SNORD36B	-0.021573
HLA-B	0.021539
CDK6	-0.021496
ALAS1	0.021476
ROR2	0.021463
RASAL2	-0.021449
SNORD115-44	0.021437
MRPL40	-0.021433
P2RY2	-0.021427
DOCK10	-0.021427
GTPBP10	-0.021424
DAPP1	0.021406
UTP20	-0.021403
HLA-A	0.021393
FDXACB1	-0.021392
SLC1A4	-0.021383
TAS2R50	-0.021371
OGFR	0.021357
LRRC8C	-0.021345
KPNA3	-0.021329
SNORD79	-0.021314
LRRC37B	-0.021269
RARB	0.021233
CTSW	-0.021225
STAMBPL1	-0.021201
NLN	-0.021197
FAM118B	-0.021172
SNORD58A	-0.021167
ZNF480	-0.021162
DUSP6	0.021136
ASRGL1	0.021106
IFI35	0.021104
APOO	-0.021100
ERAP2	0.021098
PACRGL	-0.021086
SNORD45A	-0.021086
C15orf61	-0.021078
ANPEP	-0.021052
POLR1B	-0.021040
ICAM4	0.021004
SNORD13	-0.021000
TAS2R31	-0.020990
CCDC26	-0.020981
EBAG9	-0.020959
CBLL1	-0.020912
HLA-C	0.020899
SNORD51	-0.020890
PAK1IP1	-0.020850
CHORDC1	-0.020844
VTRNA1-1	-0.020840
SLC20A1	-0.020820
GPAM	-0.020790
IFT57	-0.020783
FFAR3	0.020780
C12orf75	-0.020776
SERPINB2	0.020769
NPM3	-0.020750
CCR1	0.020723
SNORA76A	-0.020719
BCL2	-0.020705
SLFN5	0.020669
GTF2H1	-0.020632
LRRC8B	-0.020608
CSPP1	-0.020599
PTGS1	0.020591
CYP2R1	-0.020581
FBN2	-0.020573
PPP1R12B	-0.020552
ZNF138	-0.020545
DDX60L	0.020541
NUFIP1	-0.020490
ALCAM	-0.020486
POLR3G	-0.020481
CYP4F3	0.020471
NOL7	-0.020461
KIF15	-0.020455
SCAMP1	-0.020397
HVCN1	-0.020390
RALGAPA1	-0.020386
PDXDC2P	-0.020385
TAF2	-0.020366
CTSD	0.020356
IQGAP2	-0.020353
CHIC2	-0.020327
OTUD6B	-0.020307
RDH10	-0.020306
ASGR2	-0.020275
GPR85	-0.020260
SNORD78	-0.020250
CHRNA5	-0.020243
ANXA1	-0.020217
CHML	-0.020171
ZBTB8OS	-0.020154
SLC25A19	-0.020125
TOMM22	-0.020119
AFF2	-0.020111
ATMIN	-0.020095
PFKFB4	0.020093
ERGIC2	-0.020074
MRPL35	-0.020073
PTPRE	-0.020039
SPATA5	-0.020005
COTL1	0.019999
PIK3R4	-0.019977
CTSS	0.019967
ZNF280C	-0.019957
C6orf99	-0.019950
UTP15	-0.019948
DUSP10	-0.019917
MPP6	-0.019869
WDR75	-0.019852
SCFD2	-0.019838
LRRC25	0.019835
PHACTR4	-0.019831
ZNF473	-0.019816
ZC3HAV1L	-0.019815
OAS1	0.019808
LSM5	-0.019805
RPP38	-0.019794
ADI1	-0.019790
MINA	-0.019786
MARC1	-0.019778
PCMT1	-0.019775
MCM8	-0.019763
HRSP12	-0.019731
ZNF271	-0.019729
APBB1IP	0.019721
RWDD4	-0.019713
ZNF737	-0.019701
IRAK3	-0.019694
SNORD115-33	0.019688
CYB5D1	-0.019675
PTAR1	-0.019665
HOOK3	-0.019645
P2RY13	0.019641
ZNF566	-0.019617
IPO11	-0.019584
SGOL1	-0.019559
LILRA5	0.019553
ZNF398	-0.019549
BBS10	-0.019539
FARS2	-0.019534
ATG2B	-0.019533
TULP3	-0.019517
MRPL13	-0.019517
MRC2	-0.019495
GLMN	-0.019488
SLC30A6	-0.019479
PARP9	0.019465
PALLD	0.019463
CCDC34	-0.019440
CEBPB	0.019437
SNORD115-21	0.019422
KIF20B	-0.019422
CENPH	-0.019415
USP14	-0.019411
TNF	-0.019382
GTF2A2	-0.019381
FLJ45950	0.019351
TCF12	-0.019351
NUP88	-0.019332
CEACAM1	0.019330
PDCD4	0.019317
ATXN7L1	-0.019273
MINOS1	0.019271
CISD1	-0.019251
SNORD115-35	0.019236
NETO2	-0.019233
HEXB	-0.019231
C1orf112	-0.019219
SERPINB8	-0.019218
FOPNL	-0.019212
TMEM184C	-0.019204
ATF7IP2	-0.019201
METTL1	-0.019160
SPDL1	-0.019147
UBA7	0.019144
MIR125B1	0.019141
TXNL4A	-0.019125
SSBP2	-0.019120
USP13	-0.019116
KIAA0586	-0.019114
KCNQ5	-0.019092
IRX3	-0.019092
POP4	-0.019085
PSMB6	-0.019077
MIR98	0.019062
RAB3C	-0.019044
GPR34	0.019038
SLC31A1	-0.019031
ITGA6	0.019004
ANKRD12	-0.018998
MND1	-0.018949
DSCC1	-0.018947
EPX	-0.018920
SETMAR	-0.018898
INTS4	-0.018877
LGALS1	-0.018876
OXNAD1	-0.018876
ZNF385A	0.018858
SNORA4	-0.018850
CENPU	-0.018842
CEBPE	0.018839
MCAM	-0.018836
MANEA	-0.018835
C5orf30	-0.018811
SNAPC3	-0.018798
IFI6	0.018796
TMEM116	-0.018758
MT1X	-0.018756
CCDC86	-0.018739
RAB38	-0.018726
REEP5	-0.018709
MLH3	-0.018673
PRDX5	0.018673
AKR1B1	-0.018657
COX5B	-0.018621
TMEM156	0.018604
REPS1	-0.018595
UFSP2	-0.018591
BRCA2	-0.018587
WT1	-0.018581
DCP1A	-0.018571
MLLT10	-0.018568
CENPE	-0.018558
WDR3	-0.018543
TRAK2	-0.018536
TRAM2	-0.018535
QSER1	-0.018532
CCDC88B	0.018508
MGST2	0.018493
SLC27A2	-0.018492
MRTO4	-0.018480
SNORA75	-0.018473
PUS7	-0.018467
MMP2	-0.018459
MINPP1	-0.018450
ACSS2	0.018436
DIMT1	-0.018426
SNORD15A	-0.018426
LRRC58	-0.018414
ST3GAL6	-0.018410
PIGW	-0.018391
HIP1	-0.018383
SNORD115-31	0.018366
ERI1	-0.018352
GPR160	0.018350
SPANXN3	0.018348
CCDC59	-0.018347
ATP6V0A2	-0.018318
IVNS1ABP	0.018318
RTKN2	-0.018315
TMTC3	-0.018306
ECD	-0.018298
JAG1	-0.018291
STARD4	0.018286
OLA1	-0.018284
CHPT1	-0.018281
CTNNAL1	-0.018271
SND1-IT1	-0.018271
HAUS1	-0.018268
FAM101B	-0.018260
XRCC2	-0.018253
ARSK	-0.018252
MARCH3	-0.018243
ANAPC10	-0.018237
SLCO4C1	0.018223
HMBS	-0.018222
NT5DC3	-0.018219
FARSB	-0.018208
LGALS9	0.018182
CEP170	-0.018181
WT1-AS	-0.018166
LCLAT1	-0.018165
PRUNE	-0.018164
ZNF43	-0.018161
XRCC6BP1	-0.018149
SMAD2	-0.018117