!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	BPDE
!smiles	C1=CC2=C3C(=C1)C=CC4=C3C(=CC5=C4C6C(O6)C(C5O)O)C=C2
!pubchem_cid	41322
!cell_type	WI-38  Lung fibroblasts - 1uM
!organism	human
!end_metadata
TUBA1C	-0.250719
TUBA1B	-0.231149
COX1	-0.210548
TUBB	-0.164991
LDHA	-0.145440
COL1A2	-0.140320
TUBB4B	-0.125766
ACTG1	-0.125192
RPL32	0.124544
TUBB6	-0.114242
GADD45A	0.113648
COL1A1	-0.100615
ACTB	-0.097889
TUBB3	-0.096023
TUBA1A	-0.095578
COL6A3	-0.093179
GARS	-0.090405
KPNA2	-0.088693
FTL	0.087421
HIST1H2BK	0.086726
SERPINH1	-0.086346
SERPINB2	0.084902
SAT1	0.084802
EEF2	-0.084424
HSPA8	-0.081808
SRP14	0.080019
RPS5	0.079164
TFPI2	0.078568
RPS17	0.077260
RPL12	0.073949
RPL23A	0.073757
RPL24	0.073257
PFN1	-0.072642
RPL21	0.072030
UBA52	0.069016
PTGES3	-0.068628
RPL36A	0.068553
RPS14P3	0.067532
PMAIP1	0.066562
RPS10	0.066157
TM4SF1	0.065684
COL3A1	-0.065090
RPS18	0.064183
RPSA	0.063070
H2AFZ	-0.062778
IGFBP3	0.062643
MMP1	0.062525
RPL30	0.062439
ISCU	0.062129
VIM	-0.061875
GPRC5A	0.060672
SLC38A2	-0.060550
COX2	-0.060046
MT1HL1	0.059898
NDUFA4	0.059706
HMGN2	-0.059271
RPL41	0.058779
RPS20	0.058435
GAPDH	0.057847
SNRPD2	0.057231
TMSB10	0.057138
SGK1	0.056871
RPL9	0.056129
UAP1	-0.055574
CKS2	-0.055295
CDKN1A	0.054874
USMG5	0.054470
EEF1B2	0.053029
SOD1	0.052395
MTCH1	0.052361
RPLP0	0.051902
UQCRH	0.051805
LAPTM4A	0.051658
RPL34	0.051381
RPS19	0.051373
RPL35	0.050756
ID3	0.050583
COX7A2	0.050473
RPS29	0.049966
RPS27	0.049316
SLC25A5	-0.049178
ANP32B	-0.049113
RPL39	0.048625
COX6C	0.048136
SERINC1	0.047648
PTX3	-0.047498
RPS15	0.046322
CAV1	-0.046161
PSAT1	-0.046060
TMEM158	-0.045326
NCOA4	0.044896
GAS6	-0.044854
TMA7	0.044528
RPS25	0.044428
STOM	0.043381
NGFRAP1	0.043127
RPS21	0.043024
RPL29	0.042618
CORO1C	-0.042581
ATP6	-0.042437
RPS3	0.042276
LOXL1	-0.042247
TNFRSF10D	0.042001
PTTG1	-0.040920
RPL11	0.040194
RPL31	0.039729
RPL19	0.039516
FAU	0.039394
PPIB	-0.039120
RPLP1	0.039025
RRM2	-0.038729
ANLN	-0.038562
SERF2	0.038483
RPL22L1	-0.038341
ERH	-0.038334
FTH1	0.038031
RPL22	0.037771
RPS3A	0.037486
EIF4A1	-0.037318
IER2	0.037224
COX8A	0.037210
TRIAP1	0.037026
RPS12	0.036820
VDAC2	0.036782
CALM2	-0.036664
IRF2BPL	0.036140
PTTG1IP	0.036087
RPL17	0.035977
DDIT4	-0.035867
YBX1	0.035748
MT2A	0.035734
HMGB1	-0.035640
S100A13	0.035410
COX6B1	0.035102
CD63	0.034863
ID1	0.034576
ATP6V0E1	0.034149
IER3	0.034002
PFDN5	0.033943
PRC1	-0.033794
RPS11	0.033767
EIF3E	-0.033476
ATP5L	0.033079
RPL6	0.032903
RPS2	0.032831
MAP1LC3B	0.032562
RPS24	0.032560
RPS26	0.032515
HIST1H2BD	0.032414
MIF	0.032382
MRPL3	-0.032340
PRDX4	0.032265
FTH1P5	0.032252
COL6A2	-0.032184
ITM2B	0.032134
HSPA5	-0.032007
MAFF	0.031929
UBL5	0.031842
NDUFA13	0.031809
TMBIM6	0.031770
GNG5	-0.031552
CHCHD2	0.031468
OST4	0.031386
SEP15	0.031369
H2BFS	0.031287
APEX1	-0.031072
CCNB1	-0.030976
ID2	0.030914
HEXB	0.030511
TXNDC17	0.030311
TWSG1	0.030256
UQCRQ	0.030020
GDI2	-0.029963
NEDD8	0.029959
RPL27	0.029884
AK3	0.029773
GJA1	-0.029729
CDC20	-0.029665
TUBB2A	-0.029609
PTMA	-0.029258
ARPC1A	-0.029122
B2M	0.029101
HMGA1	-0.028880
MGST1	0.028735
EEF1G	0.028715
HIST1H2AC	0.028616
ATP5J	0.028587
CYR61	-0.028445
VAMP3	0.028410
GABARAPL2	0.028385
TPX2	-0.028353
CLIC1	-0.028262
CXCL8	0.028250
ATP5A1	-0.028209
POSTN	-0.028156
RPL13A	0.028126
C4orf3	0.028111
SNHG6	0.028029
NID2	0.027938
RPL37A	0.027887
KRTAP1-5	0.027857
COL5A2	-0.027699
GNG11	0.027501
RAP1B	-0.027470
RPL28	0.027461
VCAM1	-0.027454
TOB1	0.027429
RPS16	0.027263
TCEB2	0.027254
MSN	-0.027151
HMGB2	-0.027137
MYL12B	0.027014
ATF4	-0.027005
HINT1	0.026738
RPS15A	0.026645
HNRNPAB	-0.026630
UBE2S	-0.026542
RGMB	-0.026481
NPM1	-0.026475
RASA1	-0.026329
UQCRB	0.026122
ATP5E	0.026070
MARCKSL1	-0.026057
COX4I1	0.026032
CD164	0.026007
NEAT1	0.026003
NDUFA1	0.025980
RPL7A	-0.025964
PDLIM1	-0.025785
SMS	-0.025769
LGALS1	0.025745
SAP18	0.025708
ARL6IP5	0.025702
RPL26	0.025671
IARS	-0.025666
RPS27L	0.025511
COL4A2	-0.025339
RPLP2	0.025183
SERPINE1	-0.025176
TNC	-0.025171
LAMTOR5	0.025069
FAS	0.025066
COX7C	0.025033
ASNS	-0.024973
CHMP5	0.024921
MRFAP1	-0.024807
CAPN2	-0.024695
UBE2C	-0.024677
TRAM1	0.024654
DPYSL2	-0.024622
BNIP3L	0.024545
RPS8	0.024445
MT1E	0.024270
PTP4A2	-0.024046
MTHFD2	-0.023929
GSTO1	0.023848
S100A11	0.023831
TMEM50A	0.023739
SNHG8	0.023720
TXN	0.023543
RNASEK	0.023491
COX6A1	0.023476
SSR4	0.023428
GPX1	0.023348
TP53I3	0.023308
H3F3B	-0.023056
DHX15	-0.023018
UHRF1	-0.023007
HNRNPA1	-0.022865
VKORC1	0.022815
SNHG1	0.022635
HIST1H2BG	0.022618
BCAT1	-0.022614
TMEM59	0.022425
DYNLRB1	0.022419
GTF3C6	0.022382
ACTG2	-0.022312
PGAM1	0.022274
FLNA	-0.022206
S100A10	0.022171
YWHAQ	-0.022157
SNRPB	-0.022135
ACTR3	-0.022100
RAN	-0.021942
TIMP1	0.021902
CHAC1	-0.021894
ATP6V1F	0.021834
TCF21	0.021742
ATP6V1E1	0.021707
ATP5H	0.021698
PBK	-0.021663
RPL37	0.021632
EEF1A1	-0.021570
BTF3	0.021535
PHB2	-0.021482
TMEM47	0.021391
HIST1H1C	0.021332
C14orf2	0.021285
FAM96B	0.021270
CDIPT	0.021094
CTSC	-0.021072
FOSL1	-0.021049
SH3BGRL	0.021042
RPL27A	0.021003
RPL14	0.020950
RPL38	0.020891
DUSP1	0.020766
ANXA4	0.020633
HSPD1	-0.020581
FOXD1	-0.020544
PAM	0.020537
PRDX1	0.020480
RPN1	-0.020427
EIF4A2	0.020269
HERPUD1	-0.020263
HMMR	-0.020240
DLGAP5	-0.020220
IGFBP7	0.020204
PKM	-0.020191
FBL	-0.020147
NPTN	0.020108
RACGAP1	-0.020103
DYNLT3	0.020089
EIF2S2	-0.020081
ODC1	-0.020055
RPL36	0.019991
ZFAS1	0.019969
SEC13	-0.019955
NDUFA12	0.019879
RPL15	0.019844
RPL8	0.019797
ATP6AP2	0.019770
MELK	-0.019758
DCTN3	0.019757
HNRNPK	-0.019564
RAB8A	-0.019563
NDUFS6	0.019536
SNRPG	-0.019497
PGRMC1	0.019433
DSTN	0.019427
PARK7	0.019372
KIF20A	-0.019298
IER5	0.019241
MORF4L2	-0.019222
SEPW1	0.019218
RFK	0.019186
CS	-0.019177
SLC25A6	-0.019093
UQCR11	0.019016
CEMIP	-0.018930
IL11	0.018902
RPL18	0.018873
ACTN1	-0.018846
EIF4EBP1	-0.018841
RPN2	0.018819
UFC1	0.018757
ATP5I	0.018752
HIGD1A	0.018737
ITGAE	0.018722
PCBP1	-0.018641
SKP1	0.018627
UQCR10	0.018622
TNFRSF11B	-0.018611
SERPINB7	0.018603
SDCBP	0.018600
PLOD2	0.018587
KDELR2	-0.018583
QSOX1	-0.018480
FSTL1	0.018443
RPS7	-0.018396
RPL23	0.018390
KIAA0101	-0.018375
CEP55	-0.018358
WARS	-0.018297
YWHAG	-0.018288
PXDN	-0.018281
PCNA	0.018245
GLIPR1	0.018237
FST	-0.018195
TBCA	0.018186
HLA-A	0.018163
SRSF2	-0.018139
CHN1	0.018070
MIR100HG	-0.018060
FAM162A	0.018018
LRRC17	-0.018000
HSBP1	0.017985
OAZ1	0.017923
CDKN3	-0.017883
S100A16	-0.017831
UBE2E3	-0.017814
RPS28	0.017800
RSRP1	0.017784
WDR83OS	0.017739
ANXA6	-0.017736
XPOT	-0.017649
MRPL33	0.017647
GABARAP	0.017631
ITGA5	-0.017611
YWHAZ	-0.017454
ATP6V0C	0.017433
COX5B	0.017330
PABPC1	-0.017317
RPS23	0.017316
NONO	-0.017268
HBEGF	0.017228
TMEM30A	0.017166
TIMP2	0.017128
SLC7A5	-0.017108
PET100	0.017097
ATP6V1G1	0.017077
OXTR	-0.017014
MT1F	0.016998
AARS	-0.016971
BCAP31	0.016937
SLC16A4	0.016915
SMURF2	-0.016910
EGR1	0.016850
PSMA6	0.016728
SSR2	-0.016670
ADAMTS1	-0.016661
KPNB1	-0.016644
BRK1	0.016601
PLIN3	-0.016595
HSPE1	-0.016484
RPS27A	0.016483
GDF15	0.016463
NARS	-0.016452
FAM83D	-0.016424
WNT5A	0.016406
RNF11	0.016384
SRSF3	-0.016315
PFN2	-0.016291
TRIM22	0.016289
TMEM14C	0.016251
SLC30A1	0.016234
POLR2L	0.016189
LPAR1	-0.016185
DCTN6	0.016178
C19orf10	0.016110
PGK1	0.016020
BUB3	-0.016005
SMC4	-0.015976
ZWINT	-0.015964
ATRAID	0.015915
WRB	0.015841
SNHG16	-0.015809
NDUFAB1	0.015792
CCT2	-0.015780
CENPW	-0.015759
ATF3	0.015732
ATP5J2	0.015716
PSMC1	0.015682
TAF7	0.015660
SACS	-0.015652
CLDN11	-0.015644
ANXA5	-0.015608
ILK	-0.015584
MT1X	0.015554
RNF181	0.015550
CD99	0.015504
NACA	0.015491
DEK	-0.015479
BUB1B	-0.015477
SUMO2	-0.015403
NUSAP1	-0.015343
EMC4	0.015323
C12orf57	0.015322
BLOC1S2	0.015307
NDUFB4	0.015284
MAD2L1	-0.015245
CLTC	-0.015242
HLA-B	0.015229
CD59	0.015207
SNX3	0.015145
CDCA3	-0.015117
DNAJA1	0.015064
PPA1	-0.015048
ARRDC4	0.014989
CEP170	-0.014965
IFITM2	0.014906
CTNNAL1	-0.014861
PSMB4	0.014831
AMZ2	0.014827
ARL6IP1	-0.014817
CCT5	-0.014798
GPX4	0.014797
MGST3	0.014760
SNHG19	0.014749
SDC4	0.014739
CTHRC1	-0.014690
SNHG5	0.014653
SLC25A3	-0.014617
PTRF	-0.014541
ST13	0.014488
HIST1H2BE	0.014472
SARAF	0.014441
NDUFA6	0.014412
CCNDBP1	0.014386
NNMT	-0.014350